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All Outputs (18)

Prevalence of chronic obstructive pulmonary disease (COPD) in China in 1990 and 2010 (2017)
Journal Article
Chan, K. Y., Li, X., Chen, W., Song, P., Wong, N. W. K., Poon, A. N., …Rudan, I. (2017). Prevalence of chronic obstructive pulmonary disease (COPD) in China in 1990 and 2010. Journal of Global Health, 7(2), Article 020704. https://doi.org/10.7189/jogh.07.020704

BACKGROUND: Chronic obstructive pulmonary disease (COPD) is set to become the third most frequent cause of death and also the third largest cause of global morbidity by 2020. In China, where the population is aging rapidly, COPD has become one of the... Read More about Prevalence of chronic obstructive pulmonary disease (COPD) in China in 1990 and 2010.

Does FeNO Predict Clinical Characteristics in Chronic Cough? (2017)
Journal Article
Sadeghi, M. H., Wright, C. E., Hart, S., Crooks, M., & Morice, A. H. (2018). Does FeNO Predict Clinical Characteristics in Chronic Cough?. Lung, 196(1), 59-64. https://doi.org/10.1007/s00408-017-0074-6

© 2017, The Author(s). Purpose: To evaluate whether exhaled nitric oxide measurement can facilitate in the assessment of chronic cough patients based on their airway inflammatory phenotype. Methods: We have studied consecutive patients attending a sp... Read More about Does FeNO Predict Clinical Characteristics in Chronic Cough?.

Smoke-free legislation and paediatric hospitalisations for acute respiratory tract infections: national quasi-experimental study with unexpected findings and important methodological implications (2017)
Journal Article
Been, J. V., Mackay, D. F., Millett, C., Soyiri, I., van Schayck, C. P., Pell, J. P., & Sheikh, A. (2018). Smoke-free legislation and paediatric hospitalisations for acute respiratory tract infections: national quasi-experimental study with unexpected findings and important methodological implications. Tobacco Control, 27(e2), e160-e166. https://doi.org/10.1136/tobaccocontrol-2017-053801

Objectives We investigated whether Scottish implementation of smoke-free legislation was associated with a reduction in unplanned hospitalisations or deaths (‘events’) due to respiratory tract infections (RTIs) among children. Design Interrupted tim... Read More about Smoke-free legislation and paediatric hospitalisations for acute respiratory tract infections: national quasi-experimental study with unexpected findings and important methodological implications.

Land cover and air pollution are associated with asthma hospitalisations: a cross-sectional study (2017)
Journal Article
Alcock, I., White, M., Cherrie, M., Wheeler, B., Taylor, J., McInnes, R., …Fleming, L. (2017). Land cover and air pollution are associated with asthma hospitalisations: a cross-sectional study. Environment International, 109, 29-41. https://doi.org/10.1016/j.envint.2017.08.009

Background There is increasing policy interest in the potential for vegetation in urban areas to mitigate harmful effects of air pollution on respiratory health. We aimed to quantify relationships between tree and green space density and asthma-relat... Read More about Land cover and air pollution are associated with asthma hospitalisations: a cross-sectional study.

TIGA-CUB – manualised psychoanalytic child psychotherapy versus treatment as usual for children aged 5–11 years with treatment-resistant conduct disorders and their primary carers: study protocol for a randomised controlled feasibility trial (2017)
Journal Article
Edginton, E., Walwyn, R., Burton, K., Cicero, R., Graham, L., Reed, S., …Cottrell, D. (2017). TIGA-CUB – manualised psychoanalytic child psychotherapy versus treatment as usual for children aged 5–11 years with treatment-resistant conduct disorders and their primary carers: study protocol for a randomised controlled feasibility trial. Trials, 18(1), Article 431. https://doi.org/10.1186/s13063-017-2166-2

Background: The National Institute for Health and Care Excellence (NICE) recommends evidence-based parenting programmes as a first-line intervention for conduct disorders (CD) in children aged 5–11 years. As these are not effective in 25–33% of cases... Read More about TIGA-CUB – manualised psychoanalytic child psychotherapy versus treatment as usual for children aged 5–11 years with treatment-resistant conduct disorders and their primary carers: study protocol for a randomised controlled feasibility trial.

Radical cystectomy (bladder removal) against intravesical BCG immunotherapy for high-risk non-muscle invasive bladder cancer (BRAVO): a protocol for a randomised controlled feasibility study (2017)
Journal Article
Noon, A. P., Chahal, R., Dooldeniya, M., Koenig, P., Catto, J. W. F., Oughton, J. B., …Catto, J. (2017). Radical cystectomy (bladder removal) against intravesical BCG immunotherapy for high-risk non-muscle invasive bladder cancer (BRAVO): a protocol for a randomised controlled feasibility study. BMJ open, 7(8), e017913. https://doi.org/10.1136/bmjopen-2017-017913

Introduction High-risk non-muscle invasive bladder cancer (HRNMIBC) is a heterogeneous disease that can be difficult to predict. While around 25% of cancers progress to invasion and metastases, the remaining majority of tumours remain within the blad... Read More about Radical cystectomy (bladder removal) against intravesical BCG immunotherapy for high-risk non-muscle invasive bladder cancer (BRAVO): a protocol for a randomised controlled feasibility study.

The effectiveness of an intervention to reduce alcohol-related violence in premises licensed for the sale and on-site consumption of alcohol: a randomized controlled trial (2017)
Journal Article
Moore, S. C., Alam, M. F., Heikkinen, M., Hood, K., Huang, C., Moore, L., …Williams, A. (2017). The effectiveness of an intervention to reduce alcohol-related violence in premises licensed for the sale and on-site consumption of alcohol: a randomized controlled trial. Addiction, 112(11), 1898-1906. https://doi.org/10.1111/add.13878

Background and Aims: Premises licensed for the sale and consumption of alcohol can contribute to levels of assault-related injury through poor operational practices that, if addressed, could reduce violence. We tested the real-world effectiveness of... Read More about The effectiveness of an intervention to reduce alcohol-related violence in premises licensed for the sale and on-site consumption of alcohol: a randomized controlled trial.

Cost-effectiveness of outpatient parenteral antibiotic therapy: a simulation modelling approach (2017)
Journal Article
Vargas-Palacios, A., Meads, D. M., Twiddy, M., Murray, C. C., Hulme, C., Mitchell, E. D., …Minton, J. (2017). Cost-effectiveness of outpatient parenteral antibiotic therapy: a simulation modelling approach. The journal of antimicrobial chemotherapy, 72(8), 2392-2400. https://doi.org/10.1093/jac/dkx123

© The Author 2017. Published by Oxford University Press on behalf of the British Society for Antimicrobial Chemotherapy. All rights reserved. Objectives: In the UK, patients who require intravenous antimicrobial (IVA) treatment may receive this in th... Read More about Cost-effectiveness of outpatient parenteral antibiotic therapy: a simulation modelling approach.

Ignorability for general longitudinal data (2017)
Journal Article
Farewell, D. M., Huang, C., & Didelez, V. (2017). Ignorability for general longitudinal data. Biometrika, 104(2), 317-326. https://doi.org/10.1093/biomet/asx020

Likelihood factors that can be disregarded for inference are termed ignorable. We demonstrate that close ties exist between ignorability and identification of causal effects by covariate adjustment. A graphical condition, stability, plays a role anal... Read More about Ignorability for general longitudinal data.

Quality of life in patients with intermittent claudication (2017)
Journal Article
Harwood, A. E., Totty, J. P., Broadbent, E., Smith, G. E., & Chetter, I. C. (2017). Quality of life in patients with intermittent claudication. Gefässchirurgie, 22(3), 159-164. https://doi.org/10.1007/s00772-017-0269-4

© 2017, The Author(s). Background: Intermittent claudication (IC) is a common condition that causes pain in the lower limbs when walking and has been shown to severely impact the quality of life (QoL) of patients. The QoL is therefore often regarded... Read More about Quality of life in patients with intermittent claudication.

Clinical and cost-effectiveness, safety and acceptability of community intravenous antibiotic service models: CIVAS systematic review (2017)
Journal Article
Murray, C. C., Mitchell, E. D., Czoski Murray, C., Meads, D., Minton, J., Wright, J., & Twiddy, M. (2017). Clinical and cost-effectiveness, safety and acceptability of community intravenous antibiotic service models: CIVAS systematic review. BMJ open, 7(4), Article e013560. https://doi.org/10.1136/bmjopen-2016-013560

OBJECTIVE: Evaluate evidence of the efficacy, safety, acceptability and cost-effectiveness of outpatient parenteral antimicrobial therapy (OPAT) models. DESIGN: A systematic review. DATA SOURCES: MEDLINE, EMBASE, CINAHL, Cochrane Library, National He... Read More about Clinical and cost-effectiveness, safety and acceptability of community intravenous antibiotic service models: CIVAS systematic review.

Continuous cough monitoring using ambient sound recording during convalescence from a COPD exacerbation (2017)
Journal Article
Crooks, M. G., den Brinker, A., Hayman, Y., Williamson, J. D., Innes, A., Wright, C. E., …Morice, A. H. (2017). Continuous cough monitoring using ambient sound recording during convalescence from a COPD exacerbation. Lung, 195(3), 289-294. https://doi.org/10.1007/s00408-017-9996-2

Purpose Cough is common in chronic obstructive pulmonary disease (COPD) and is associated with frequent exacerbations and increased mortality. Cough increases during acute exacerbations (AE-COPD), representing a possible metric of clinical deteriorat... Read More about Continuous cough monitoring using ambient sound recording during convalescence from a COPD exacerbation.

Oral and topical antibiotics for clinically infected eczema in children: A pragmatic randomized controlled trial in ambulatory care (2017)
Journal Article
Francis, N. A., Ridd, M. J., Thomas-Jones, E., Butler, C. C., Hood, K., Shepherd, V., …Sullivan, F. (2017). Oral and topical antibiotics for clinically infected eczema in children: A pragmatic randomized controlled trial in ambulatory care. Annals of Family Medicine, 15(2), 124-130. https://doi.org/10.1370/afm.2038

PURPOSE Eczema may flare because of bacterial infection, but evidence supporting antibiotic treatment is of low quality. We aimed to determine the effect of oral and topical antibiotics in addition to topical emollient and corticosteroids in children... Read More about Oral and topical antibiotics for clinically infected eczema in children: A pragmatic randomized controlled trial in ambulatory care.

A calibration method for non-positive definite covariance matrix in multivariate data analysis (2017)
Journal Article
Huang, C., Farewell, D., & Pan, J. (2017). A calibration method for non-positive definite covariance matrix in multivariate data analysis. Journal of Multivariate Analysis, 157, 45-52. https://doi.org/10.1016/j.jmva.2017.03.001

Covariance matrices that fail to be positive definite arise often in covariance estimation. Approaches addressing this problem exist, but are not well supported theoretically. In this paper, we propose a unified statistical and numerical matrix calib... Read More about A calibration method for non-positive definite covariance matrix in multivariate data analysis.

Extracorporeal shockwave therapy for the treatment of lower limb intermittent claudication: Study protocol for a randomised controlled trial (the SHOCKWAVE 1 trial) (2017)
Journal Article
Harwood, A. E., Smith, G. E., Totty, J. P., Carradice, D., Chetter, I. C., Harwood, A., …Smith, G. (2017). Extracorporeal shockwave therapy for the treatment of lower limb intermittent claudication: Study protocol for a randomised controlled trial (the SHOCKWAVE 1 trial). Trials, 18(1), https://doi.org/10.1186/s13063-017-1844-4

© 2017 The Author(s). Background: Peripheral arterial disease (PAD) has a population prevalence of 4.6% with intermittent claudication (IC) presenting as one of the earliest and most common symptoms. PAD has detrimental effects on patients' walking a... Read More about Extracorporeal shockwave therapy for the treatment of lower limb intermittent claudication: Study protocol for a randomised controlled trial (the SHOCKWAVE 1 trial).

Dialkylcarbamoyl chloride (DACC)-coated dressings in the management and prevention of wound infection: A systematic review (2017)
Journal Article
Totty, J., Bua, N., Smith, G., Harwood, A., Carradice, D., Wallace, T., & Chetter, I. (2017). Dialkylcarbamoyl chloride (DACC)-coated dressings in the management and prevention of wound infection: A systematic review. Journal of Wound Care, 26(3), 107-114. https://doi.org/10.12968/jowc.2017.26.3.107

Objective: Dialkylcarbomoyl chloride (DACC)-coated dressings (Leukomed Sorbact and Cutimed Sorbact) irreversibly bind bacteria at the wound surface that are then removed when the dressing is changed. They are a recent addition to the wound care profe... Read More about Dialkylcarbamoyl chloride (DACC)-coated dressings in the management and prevention of wound infection: A systematic review.

Predicting probable Alzheimer's disease using linguistic deficits and biomarkers (2017)
Journal Article
Orimaye, S. O., Wong, J. S., Golden, K. J., Wong, C. P., & Soyiri, I. N. (2017). Predicting probable Alzheimer's disease using linguistic deficits and biomarkers. BMC Bioinformatics, 18(1), Article 34. https://doi.org/10.1186/s12859-016-1456-0

Background The manual diagnosis of neurodegenerative disorders such as Alzheimer’s disease (AD) and related Dementias has been a challenge. Currently, these disorders are diagnosed using specific clinical diagnostic criteria and neuropsychological ex... Read More about Predicting probable Alzheimer's disease using linguistic deficits and biomarkers.