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high INtensity Interval Training In pATiEnts with intermittent claudication (INITIATE): protocol for a multi-centre, proof-of-concept, prospective interventional study (2020)
Journal Article
Pymer, S., Harwood, A., Ibeggazene, S., McGregor, G., Huang, C., Twiddy, M., …Chetter, I. C. (2020). high INtensity Interval Training In pATiEnts with intermittent claudication (INITIATE): protocol for a multi-centre, proof-of-concept, prospective interventional study. BMJ open, 10(7), https://doi.org/10.1136/bmjopen-2020-038825

Introduction: The first-line recommended treatment for patients with intermittent claudication (IC), is a supervised exercise programme (SEP), which includes a minimum of 2 hours exercise per week over a 12-week period. However, provision, uptake, an... Read More about high INtensity Interval Training In pATiEnts with intermittent claudication (INITIATE): protocol for a multi-centre, proof-of-concept, prospective interventional study.

Opioids for breathlessness: a narrative review (2020)
Journal Article
Currow, D. C., Johnson, M. J., Pollack, A., Ferreira, D. H., Kochovska, S., Ekström, M., & Harrison, C. (2020). Opioids for breathlessness: a narrative review. BMJ supportive & palliative care, https://doi.org/10.1136/bmjspcare-2020-002314

ABSTRACT Chronic breathlessness is a disabling and distressing condition for which there is a growing evidence base for a range of interventions. Non-pharmacological interventions are the mainstay of management and should be optimised prior to use... Read More about Opioids for breathlessness: a narrative review.

Laparoscopic versus Open Colorectal Surgery in the Acute Setting (LaCeS Trial): A multicentre, randomised controlled feasibility trial. (2020)
Journal Article
Harji, D., Marshall, H., Gordon, K., Twiddy, M., Pullan, A., Meads, D., …Brown, J. (in press). Laparoscopic versus Open Colorectal Surgery in the Acute Setting (LaCeS Trial): A multicentre, randomised controlled feasibility trial. British journal of surgery, https://doi.org/10.1002/bjs.11703

Abstract Background Approximately 30,000 people per annum undergo major, emergency abdominal, gastrointestinal surgery, of which 36% (~10,800) are carried out for emergency colorectal pathology. Approximately 14% of all patients requiring emergency... Read More about Laparoscopic versus Open Colorectal Surgery in the Acute Setting (LaCeS Trial): A multicentre, randomised controlled feasibility trial..

The Effects of the iPlayClean Education Programme on Doping Attitudes and Susceptibility to use Banned Substances among High-Level Adolescent Athletes from the UK: A Cluster-Randomised Control Trial (2020)
Journal Article
Huang, C. (2020). The Effects of the iPlayClean Education Programme on Doping Attitudes and Susceptibility to use Banned Substances among High-Level Adolescent Athletes from the UK: A Cluster-Randomised Control Trial. International Journal of Drug Policy, 82, https://doi.org/10.1016/j.drugpo.2020.102820

Background: This study examined the effects of the iPlayClean anti-doping intervention on attitudes towards doping and susceptibility, and whether delivery mode affected the results. Methods: A total of 1,081 high-level UK athletes (14-18 years old... Read More about The Effects of the iPlayClean Education Programme on Doping Attitudes and Susceptibility to use Banned Substances among High-Level Adolescent Athletes from the UK: A Cluster-Randomised Control Trial.

Identification of patients with potential palliative care needs: a systematic review of screening tools in primary care (2020)
Journal Article
ElMokhallalati, Y., Bradley, S. H., Chapman, E., Ziegler, L., Murtagh, F. E., Johnson, M. J., & Bennett, M. I. (in press). Identification of patients with potential palliative care needs: a systematic review of screening tools in primary care. Palliative medicine, https://doi.org/10.1177/0269216320929552

Background Despite increasing evidence of the benefits of early access to palliative care, many patients do not receive palliative care in a timely manner. A systematic approach in primary care can facilitate earlier identification of patients with... Read More about Identification of patients with potential palliative care needs: a systematic review of screening tools in primary care.

The Effects of the iPlayClean Education Programme on Doping Attitudes and Susceptibility to use Banned Substances among High-Level Adolescent Athletes from the UK: A Cluster-Randomised Control Trial (2020)
Journal Article
Nicholls, A., Morley, D., Thompson, M. A., Huang, C., Abt, G., Rothwell, M., …Ntoumanis, N. (in press). The Effects of the iPlayClean Education Programme on Doping Attitudes and Susceptibility to use Banned Substances among High-Level Adolescent Athletes from the UK: A Cluster-Randomised Control Trial. International Journal of Drug Policy,

Background: This study examined the effects of the iPlayClean anti-doping intervention on attitudes towards doping and susceptibility, and whether delivery mode affected the results. Methods: A total of 1,081 high-level UK athletes (14-18 years old... Read More about The Effects of the iPlayClean Education Programme on Doping Attitudes and Susceptibility to use Banned Substances among High-Level Adolescent Athletes from the UK: A Cluster-Randomised Control Trial.

Development of a Core Outcome Set to use in the Research and Assessment of Malignant Bowel Obstruction: protocol for the RAMBO study (2020)
Journal Article
Baddeley, E., Bravington, A., Johnson, M., Currow, D., Murtagh, F., Boland, E., …Boland, J. (2020). Development of a Core Outcome Set to use in the Research and Assessment of Malignant Bowel Obstruction: protocol for the RAMBO study. BMJ open, 10(6), https://doi.org/10.1136/bmjopen-2020-039154

Introduction: Studies regarding the management of malignant bowel obstruction (MBO) report conflicting findings. This is partly due to different outcome measures being used to evaluate severity of MBO and the response to treatments. Furthermore, curr... Read More about Development of a Core Outcome Set to use in the Research and Assessment of Malignant Bowel Obstruction: protocol for the RAMBO study.

Quality of life changes with duration of chronic breathlessness: a random sample of community-dwelling people. (2020)
Journal Article
Currow, D. C., Chang, S., Dal Grande, E., Ferreira, D. H., Kochovska, S., Kinchin PhD, I., …Ekstrom, M. (in press). Quality of life changes with duration of chronic breathlessness: a random sample of community-dwelling people. Journal of pain and symptom management, https://doi.org/10.1016/j.jpainsymman.2020.05.015

Introduction Chronic breathlessness is associated with poorer quality of life. This population study aimed to define dimensions of quality of life (QoL), and duration and dominant causes of breathlessness that most diminished QoL. Methods This... Read More about Quality of life changes with duration of chronic breathlessness: a random sample of community-dwelling people..

A randomised Phase II trial of carboplatin and gemcitabine ± vandetanib in first-line treatment of patients with advanced urothelial cell cancer not suitable to receive cisplatin: TOUCAN Phase II trial final (2020)
Journal Article
Jones, R., Crabb, S., Chester, J., Elliott, T., Huddart, R., Birtle, A., …Griffiths, G. (in press). A randomised Phase II trial of carboplatin and gemcitabine ± vandetanib in first-line treatment of patients with advanced urothelial cell cancer not suitable to receive cisplatin: TOUCAN Phase II trial final. BJU international, https://doi.org/10.1111/bju.15096

Objectives To assess the efficacy and tolerability of the dual epidermal growth factor receptor/vascular endothelial growth factor receptor inhibitor, vandetanib, in combination with carboplatin and gemcitabine in the first‐line treatment of patient... Read More about A randomised Phase II trial of carboplatin and gemcitabine ± vandetanib in first-line treatment of patients with advanced urothelial cell cancer not suitable to receive cisplatin: TOUCAN Phase II trial final.

A dyadic growth modeling approach to examine associations between weight gain and lung function decline: The NHLBI Pooled Cohorts Study (2020)
Journal Article
Cornelius, T., Schwartz, J. E., Balte, P., Bhatt, S. P., Cassano, P. A., Currow, D., …Oelsner, E. C. (in press). A dyadic growth modeling approach to examine associations between weight gain and lung function decline: The NHLBI Pooled Cohorts Study. American Journal of Epidemiology, https://doi.org/10.1093/aje/kwaa059

The relationship between body weight and lung function is complex. Using a dyadic multilevel linear modeling approach, treating body mass index (BMI) and lung function as paired, within-person outcomes, we test the hypothesis that individuals with mo... Read More about A dyadic growth modeling approach to examine associations between weight gain and lung function decline: The NHLBI Pooled Cohorts Study.

Understanding usual care in randomised controlled trials of complex interventions: A multi-method approach (2020)
Journal Article
Evans, C. J., Yorganci, E., Evans, C. J., Johnson, H., Barclay, S., Murtagh, F. E., …Koffman, J. (2020). Understanding usual care in randomised controlled trials of complex interventions: A multi-method approach. Palliative medicine, https://doi.org/10.1177/0269216320905064

Background Evaluations of complex interventions compared to usual care provided in palliative care are increasing. Not describing usual care may affect the interpretation of an intervention’s effectiveness, yet how it can be described remains unclear... Read More about Understanding usual care in randomised controlled trials of complex interventions: A multi-method approach.

Considerations on equity in management of end-stage kidney disease in low- and middle-income countries (2020)
Journal Article
Van Biesen, W., Jha, V., Abu-Alfa, A. K., Andreoli, S. P., Ashuntantang, G., Bernieh, B., …Garcia Garcia, G. (2020). Considerations on equity in management of end-stage kidney disease in low- and middle-income countries. Kidney International Supplements, 10(1), e63-e71. https://doi.org/10.1016/j.kisu.2019.11.004

Achievement of equity in health requires development of a health system in which everyone has a fair opportunity to attain their full health potential. The current, large country-level variation in the reported incidence and prevalence of treated end... Read More about Considerations on equity in management of end-stage kidney disease in low- and middle-income countries.

Minimal clinically important differences in average, best, worst and current intensity and unpleasantness of chronic breathlessness (2020)
Journal Article
Ekström, M., Johnson, M. J., Huang, C., & Currow, D. C. (2020). Minimal clinically important differences in average, best, worst and current intensity and unpleasantness of chronic breathlessness. European respiratory journal, 55(5), https://doi.org/10.1183/13993003.02202-2019

Background: Chronic breathlessness has devastating consequences. The minimal clinically important difference (MCID) for current intensity has been estimated as 9mm on a 100mm visual analogue scale (VAS). We aimed to determine MCIDs for commonly used... Read More about Minimal clinically important differences in average, best, worst and current intensity and unpleasantness of chronic breathlessness.

Information design for bowel cancer detection. The impact of using information visualization to help patients prepare for colonoscopy screening, using a booklet, a motion graphics and an App. (2019)
Journal Article
dos Santos Lonsdale, M., Ni, L., Gu, C., & Twiddy, M. (2019). Information design for bowel cancer detection. The impact of using information visualization to help patients prepare for colonoscopy screening, using a booklet, a motion graphics and an App. Information Design Journal, 25(2), 125-156. https://doi.org/10.1075/idj.25.2.01lon

Colorectal cancer is one of the most commonly occurring cancers in the world, and colonoscopy is the most sensitive procedure to detect it. Colonoscopy success depends on the quality of bowel preparation, but the way information is designed and commu... Read More about Information design for bowel cancer detection. The impact of using information visualization to help patients prepare for colonoscopy screening, using a booklet, a motion graphics and an App..

Midwives’ views of changing to a Continuity of Midwifery Care (CMC) model in Scotland: a baseline survey (2019)
Journal Article
Hollins-Martin, C. J., MacArthur, J., Martin, C. R., & McInnes, R. J. (in press). Midwives’ views of changing to a Continuity of Midwifery Care (CMC) model in Scotland: a baseline survey. Women and Birth, https://doi.org/10.1016/j.wombi.2019.08.005

Background: There is good evidence that Continuity of Midwifery Care (CMC) is associated with improved clinical outcomes, greater maternal satisfaction, and improved work experiences for midwives. Changes made to the organisation require careful impl... Read More about Midwives’ views of changing to a Continuity of Midwifery Care (CMC) model in Scotland: a baseline survey.

A feasibility, randomised controlled trial of a complex breathlessness intervention in idiopathic pulmonary fibrosis (BREEZE-IPF): study protocol (2019)
Journal Article
Crooks, M. G., Wright, C., Hart, S. P., Allgar, V., English, A., Swan, F., …Crooks, M. G. (2019). A feasibility, randomised controlled trial of a complex breathlessness intervention in idiopathic pulmonary fibrosis (BREEZE-IPF): study protocol. ERJ Open Research, 5(4), https://doi.org/10.1183/23120541.00186-2019

Introduction: Idiopathic pulmonary fibrosis (IPF) is a chronic and progressive lung disease that causes breathlessness and cough that worsen over time, limiting daily activities and negatively impacting quality of life. Although treatments are now av... Read More about A feasibility, randomised controlled trial of a complex breathlessness intervention in idiopathic pulmonary fibrosis (BREEZE-IPF): study protocol.

Presurgery conditioning interventions (prehabilitation) in adults undergoing lower limb surgery for peripheral arterial disease (2019)
Journal Article
Smith, G. E., Palmer, J., Pymer, S., Smith, G. E., Harwood, A. E., Ingle, L., …Chetter, I. C. (2019). Presurgery conditioning interventions (prehabilitation) in adults undergoing lower limb surgery for peripheral arterial disease. The Cochrane database of systematic reviews, 2019(9), https://doi.org/10.1002/14651858.cd013407

This is a protocol for a Cochrane Review (Intervention). The objectives are as follows: To assess the effectiveness of prehabilitation (preoperative exercise, either alone or in combination with nutritional or psychological interventions or both)... Read More about Presurgery conditioning interventions (prehabilitation) in adults undergoing lower limb surgery for peripheral arterial disease.

Establishing key criteria to define and compare models of specialist palliative care: a mixed-methods study using qualitative interviews and Delphi survey (2019)
Journal Article
Firth, A. M., O’Brien, S. M., Guo, P., Seymour, J., Richardson, H., Bridges, C., …Murtagh, F. E. (2019). Establishing key criteria to define and compare models of specialist palliative care: a mixed-methods study using qualitative interviews and Delphi survey. Palliative medicine, https://doi.org/10.1177/0269216319858237

Background: Specialist palliative care services have various configurations of staff, processes and interventions, which determine how care is delivered. Currently, there is no consistent way to define and distinguish these different models of care.... Read More about Establishing key criteria to define and compare models of specialist palliative care: a mixed-methods study using qualitative interviews and Delphi survey.

Health-related quality of life and well-being in people over 75 years of age with end-stage kidney disease managed with dialysis or comprehensive conservative care: A cross-sectional study in the UK and Australia (2019)
Journal Article
Shah, K. K., Murtagh, F. E., McGeechan, K., Crail, S., Burns, A., Tran, A. D., & Morton, R. L. (2019). Health-related quality of life and well-being in people over 75 years of age with end-stage kidney disease managed with dialysis or comprehensive conservative care: A cross-sectional study in the UK and Australia. BMJ open, 9(5), https://doi.org/10.1136/bmjopen-2018-027776

© Author(s) (or their employer(s)) 2018. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. Objective To measure health-related quality of life (HRQoL) and well-being in older people with end-stage ki... Read More about Health-related quality of life and well-being in people over 75 years of age with end-stage kidney disease managed with dialysis or comprehensive conservative care: A cross-sectional study in the UK and Australia.


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