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Laparoscopic versus open colorectal surgery in the acute setting (LaCeS trial): a multicentre randomized feasibility trial (2020)
Journal Article
Cardozo, W., Baker, R., Berger, C., Chapman, S., Codd, R., Coyne, P., …Brown, J. (in press). Laparoscopic versus open colorectal surgery in the acute setting (LaCeS trial): a multicentre randomized feasibility trial. British journal of surgery, https://doi.org/10.1002/bjs.11703

Abstract Background Approximately 30,000 people per annum undergo major, emergency abdominal, gastrointestinal surgery, of which 36% (~10,800) are carried out for emergency colorectal pathology. Approximately 14% of all patients requiring emergency... Read More about Laparoscopic versus open colorectal surgery in the acute setting (LaCeS trial): a multicentre randomized feasibility trial.

The effects of the iPlayClean education programme on doping attitudes and susceptibility to use banned substances among high-level adolescent athletes from the UK: A cluster-randomised controlled trial (2020)
Journal Article
Nicholls, A. R., Morley, D., Thompson, M. A., Huang, C., Abt, G., Rothwell, M., …Ntoumanis, N. (2020). The effects of the iPlayClean education programme on doping attitudes and susceptibility to use banned substances among high-level adolescent athletes from the UK: A cluster-randomised controlled trial. International Journal of Drug Policy, 82, Article 102820. https://doi.org/10.1016/j.drugpo.2020.102820

Background: This study examined the effects of the iPlayClean anti-doping intervention on attitudes towards doping and susceptibility, and whether delivery mode affected the results. Methods: A total of 1,081 high-level UK athletes (14-18 years old... Read More about The effects of the iPlayClean education programme on doping attitudes and susceptibility to use banned substances among high-level adolescent athletes from the UK: A cluster-randomised controlled trial.

Mapping geographical inequalities in childhood diarrhoeal morbidity and mortality in low-income and middle-income countries, 2000-17: analysis for the Global Burden of Disease Study 2017 Local Burden of Disease Diarrhoea Collaborators* (2020)
Journal Article
Soyiri, I., & Local Burden of Disease Diarrhoea Collaborators. (2020). Mapping geographical inequalities in childhood diarrhoeal morbidity and mortality in low-income and middle-income countries, 2000-17: analysis for the Global Burden of Disease Study 2017 Local Burden of Disease Diarrhoea Collaborators*. Lancet, 395(10239), 1779-1801. https://doi.org/10.1016/S0140-6736%2820%2930114-8

Background Across low-income and middle-income countries (LMICs), one in ten deaths in children younger than 5 years is attributable to diarrhoea. The substantial between-country variation in both diarrhoea incidence and mortality is attributable t... Read More about Mapping geographical inequalities in childhood diarrhoeal morbidity and mortality in low-income and middle-income countries, 2000-17: analysis for the Global Burden of Disease Study 2017 Local Burden of Disease Diarrhoea Collaborators*.

The Effects of the iPlayClean Education Programme on Doping Attitudes and Susceptibility to use Banned Substances among High-Level Adolescent Athletes from the UK: A Cluster-Randomised Control Trial (2020)
Journal Article
Nicholls, A., Morley, D., Thompson, M. A., Huang, C., Abt, G., Rothwell, M., …Ntoumanis, N. (in press). The Effects of the iPlayClean Education Programme on Doping Attitudes and Susceptibility to use Banned Substances among High-Level Adolescent Athletes from the UK: A Cluster-Randomised Control Trial. International Journal of Drug Policy,

Background: This study examined the effects of the iPlayClean anti-doping intervention on attitudes towards doping and susceptibility, and whether delivery mode affected the results. Methods: A total of 1,081 high-level UK athletes (14-18 years old... Read More about The Effects of the iPlayClean Education Programme on Doping Attitudes and Susceptibility to use Banned Substances among High-Level Adolescent Athletes from the UK: A Cluster-Randomised Control Trial.

Prevalence and attributable health burden of chronic respiratory diseases, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017 (2020)
Journal Article
Soriano, J. B., Kendrick, P., Paulson, K., Gupta, V., Vos, T., GBD Chronic Respiratory Disease Collaborators, & Soyiri, I. (2020). Prevalence and attributable health burden of chronic respiratory diseases, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017. The lancet. Respiratory medicine, 8(6), 585-596. https://doi.org/10.1016/S2213-2600%2820%2930105-3

Background Previous attempts to characterise the burden of chronic respiratory diseases have focused only on specific disease conditions, such as chronic obstructive pulmonary disease (COPD) or asthma. In this study, we aimed to characterise the bur... Read More about Prevalence and attributable health burden of chronic respiratory diseases, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017.

A randomised Phase II trial of carboplatin and gemcitabine ± vandetanib in first-line treatment of patients with advanced urothelial cell cancer not suitable to receive cisplatin (2020)
Journal Article
Jones, R., Crabb, S., Chester, J., Elliott, T., Huddart, R., Birtle, A., …Griffiths, G. (2020). A randomised Phase II trial of carboplatin and gemcitabine ± vandetanib in first-line treatment of patients with advanced urothelial cell cancer not suitable to receive cisplatin. BJU international, 126(2), 292-299. https://doi.org/10.1111/bju.15096

Objectives To assess the efficacy and tolerability of the dual epidermal growth factor receptor/vascular endothelial growth factor receptor inhibitor, vandetanib, in combination with carboplatin and gemcitabine in the first‐line treatment of patient... Read More about A randomised Phase II trial of carboplatin and gemcitabine ± vandetanib in first-line treatment of patients with advanced urothelial cell cancer not suitable to receive cisplatin.

Considerations on equity in management of end-stage kidney disease in low- and middle-income countries (2020)
Journal Article
Van Biesen, W., Jha, V., Abu-Alfa, A. K., Andreoli, S. P., Ashuntantang, G., Bernieh, B., …Garcia Garcia, G. (2020). Considerations on equity in management of end-stage kidney disease in low- and middle-income countries. Kidney International Supplements, 10(1), e63-e71. https://doi.org/10.1016/j.kisu.2019.11.004

Achievement of equity in health requires development of a health system in which everyone has a fair opportunity to attain their full health potential. The current, large country-level variation in the reported incidence and prevalence of treated end... Read More about Considerations on equity in management of end-stage kidney disease in low- and middle-income countries.

Development and evaluation of a screening tool to aid the diagnosis of a cluster headache (2020)
Journal Article
Buture, A., Boland, J. W., Dikomitis, L., Huang, C., & Ahmed, F. (2020). Development and evaluation of a screening tool to aid the diagnosis of a cluster headache. Brain Sciences, 10(2), Article 77. https://doi.org/10.3390/brainsci10020077

Cluster headache (CH), a severe primary headache, is often misdiagnosed and mismanaged. The aim of this study was to develop and evaluate a screening tool to aid the diagnosis of CH. We developed a novel 12-item screening tool. This was comprised of... Read More about Development and evaluation of a screening tool to aid the diagnosis of a cluster headache.

Liver resection surgery compared with thermal ablation in high surgical risk patients with colorectal liver metastases: the LAVA international RCT (2020)
Journal Article
Davidson, B., Gurusamy, K., Corrigan, N., Croft, J., Ruddock, S., Pullan, A., …de Wilt, J. H. (2020). Liver resection surgery compared with thermal ablation in high surgical risk patients with colorectal liver metastases: the LAVA international RCT. Health Technology Assessment, 24(21), 1-66. https://doi.org/10.3310/hta24210

Background: Although surgical resection has been considered the only curative option for colorectal liver metastases, thermal ablation has recently been suggested as an alternative curative treatment. There have been no adequately powered trials comp... Read More about Liver resection surgery compared with thermal ablation in high surgical risk patients with colorectal liver metastases: the LAVA international RCT.

Measuring universal health coverage based on an index of effective coverage of health services in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019 (2020)
Journal Article
Bakhtiari, A., Balachandran, A., Banach, M., Balassyano, S., Baig, A. A., Bakhshaei, M. H., …Murray, C. J. L. (2020). Measuring universal health coverage based on an index of effective coverage of health services in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019. Lancet, https://doi.org/10.1016/S0140-6736%2820%2930750-9

© 2020 Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license Background: Achieving universal health coverage (UHC) involves all people receiving the health services they need, of high quality, without experi... Read More about Measuring universal health coverage based on an index of effective coverage of health services in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019.

Information design for bowel cancer detection: The impact of using information visualisation to help patients prepare for colonoscopy screening (2019)
Journal Article
dos Santos Lonsdale, M., Ni, L. C., Gu, C., & Twiddy, M. (2019). Information design for bowel cancer detection: The impact of using information visualisation to help patients prepare for colonoscopy screening. Information Design Journal, 25(2), 125-156. https://doi.org/10.1075/idj.25.2.01lon

© 2019 John Benjamins Publishing Company. All rights reserved. Colorectal cancer is one of the most commonly occurring cancers in the world, and colonoscopy is the most sensitive procedure to detect it. Colonoscopy success depends on the quality of b... Read More about Information design for bowel cancer detection: The impact of using information visualisation to help patients prepare for colonoscopy screening.

Mapping disparities in education across low- and middle-income countries (2019)
Journal Article
Graetz, N., Woyczynski, L., Wilson, K. F., Hall, J. B., Hassen Abate, K., Abd-Allah, F., …Hay, S. I. (2020). Mapping disparities in education across low- and middle-income countries. Nature, 577(7789), 235-238. https://doi.org/10.1038/s41586-019-1872-1

Educational attainment is an important social determinant of maternal, newborn, and child health. As a tool for promoting gender equity, it has gained increasing traction in popular media, international aid strategies, and global agenda-setting. The... Read More about Mapping disparities in education across low- and middle-income countries.

Intention-to-treat analyses for randomised controlled trials in hospice/palliative care: the case for analyses to be of people exposed to the intervention. (2019)
Journal Article
Kochovska, S., Huang, C., Johnson, M. J., Agar, M. R., Fallon, M. T., Kaasa, S., …Currow, D. C. (2020). Intention-to-treat analyses for randomised controlled trials in hospice/palliative care: the case for analyses to be of people exposed to the intervention. Journal of pain and symptom management, 59(3), 637-645. https://doi.org/10.1016/j.jpainsymman.2019.10.026

© 2019 American Academy of Hospice and Palliative Medicine Context: Minimizing bias in randomized controlled trials (RCTs) includes intention-to-treat analyses. Hospice/palliative care RCTs are constrained by high attrition unpredictable when consent... Read More about Intention-to-treat analyses for randomised controlled trials in hospice/palliative care: the case for analyses to be of people exposed to the intervention..

A feasibility, randomised controlled trial of a complex breathlessness intervention in idiopathic pulmonary fibrosis (BREEZE-IPF): study protocol (2019)
Journal Article
Wright, C., Hart, S. P., Allgar, V., English, A., Swan, F., Dyson, J., …Crooks, M. G. (2019). A feasibility, randomised controlled trial of a complex breathlessness intervention in idiopathic pulmonary fibrosis (BREEZE-IPF): study protocol. ERJ Open Research, 5(4), Article 0186. https://doi.org/10.1183/23120541.00186-2019

Introduction: Idiopathic pulmonary fibrosis (IPF) is a chronic and progressive lung disease that causes breathlessness and cough that worsen over time, limiting daily activities and negatively impacting quality of life. Although treatments are now av... Read More about A feasibility, randomised controlled trial of a complex breathlessness intervention in idiopathic pulmonary fibrosis (BREEZE-IPF): study protocol.

Presurgery conditioning interventions (prehabilitation) in adults undergoing lower limb surgery for peripheral arterial disease (2019)
Journal Article
Palmer, J., Pymer, S., Smith, G. E., Harwood, A. E., Ingle, L., Huang, C., & Chetter, I. C. (2019). Presurgery conditioning interventions (prehabilitation) in adults undergoing lower limb surgery for peripheral arterial disease. The Cochrane database of systematic reviews, 2019(9), Article CD013407. https://doi.org/10.1002/14651858.cd013407

This is a protocol for a Cochrane Review (Intervention). The objectives are as follows: To assess the effectiveness of prehabilitation (preoperative exercise, either alone or in combination with nutritional or psychological interventions or both)... Read More about Presurgery conditioning interventions (prehabilitation) in adults undergoing lower limb surgery for peripheral arterial disease.

Participant engagement with a UK community-based preschool childhood obesity prevention programme: a focused ethnography study (2019)
Journal Article
Burton, W., Twiddy, M., Sahota, P., Brown, J., & Bryant, M. (2019). Participant engagement with a UK community-based preschool childhood obesity prevention programme: a focused ethnography study. BMC public health, 19(1), Article 1074. https://doi.org/10.1186/s12889-019-7410-0

© 2019 The Author(s). Background: Children's centres in the UK provide a setting for public health programmes; offering support to families living in the most disadvantaged areas where obesity prevalence is at its highest. Health, Exercise and Nutrit... Read More about Participant engagement with a UK community-based preschool childhood obesity prevention programme: a focused ethnography study.

A pilot feasibility randomised clinical trial comparing dialkylcarbamoylchloride-coated dressings versus standard care for the primary prevention of surgical site infection (2019)
Journal Article
Totty, J. P., Hitchman, L. H., Cai, P. L., Wallace, T., Harwood, A. E., Carradice, D., …Chetter, I. C. (2019). A pilot feasibility randomised clinical trial comparing dialkylcarbamoylchloride-coated dressings versus standard care for the primary prevention of surgical site infection. International wound journal, 16(4), 883-890. https://doi.org/10.1111/iwj.13113

A surgical site infection (SSI) may occur in up to 30% of procedures and results in significant morbidity and mortality. We aimed to assess the feasibility of conducting a randomised controlled trial (RCT) examining the use of dialkylcarbamoylchlorid... Read More about A pilot feasibility randomised clinical trial comparing dialkylcarbamoylchloride-coated dressings versus standard care for the primary prevention of surgical site infection.

Global, regional, and national burden of neurological disorders, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016 (2019)
Journal Article
Feigin, V. L., Nichols, E., Alam, T., Bannick, M. S., Beghi, E., Blake, N., …Vos, T. (2019). Global, regional, and national burden of neurological disorders, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016. Lancet Neurology, 18(5), 459-480. https://doi.org/10.1016/S1474-4422%2818%2930499-X

Background Neurological disorders are increasingly recognised as major causes of death and disability worldwide. The aim of this analysis from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2016 is to provide the most comprehe... Read More about Global, regional, and national burden of neurological disorders, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016.

The relationship between red blood cell distribution width and metabolic syndrome in elderly Chinese: a cross-sectional study (2019)
Journal Article
Yan, Z., Fan, Y., Meng, Z., Huang, C., Liu, M., Zhang, Q., …Jia, Q. (2019). The relationship between red blood cell distribution width and metabolic syndrome in elderly Chinese: a cross-sectional study. Lipids in Health and Disease, 18(1), Article 34. https://doi.org/10.1186/s12944-019-0978-7

© 2019 The Author(s). Objective: Metabolic syndrome (MS) is a group of risk factors which includes hypertension, hyperglycemia, abnormal cholesterol levels, and obesity. Red blood cell distribution width (RDW) is a parameter that reflects the heterog... Read More about The relationship between red blood cell distribution width and metabolic syndrome in elderly Chinese: a cross-sectional study.

Association between platelet distribution width and serum uric acid in Chinese population (2019)
Journal Article
Liu, X., Wang, H., Huang, C., Meng, Z., Zhang, W., Li, Y., …Fan, Y. (2019). Association between platelet distribution width and serum uric acid in Chinese population. BioFactors, 45(3), 326-334. https://doi.org/10.1002/biof.1491

© 2019 International Union of Biochemistry and Molecular Biology Platelet distribution width (PDW) is a simple and inexpensive parameter, which could predict activation of coagulation efficiently. And it has been confirmed to have a significant role... Read More about Association between platelet distribution width and serum uric acid in Chinese population.