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Data reduction analyses of animal behaviour: avoiding Kaiser’s criterion and adopting more robust automated methods (2019)
Journal Article
Blake Morton, F., & Altschul, D. (2019). Data reduction analyses of animal behaviour: avoiding Kaiser’s criterion and adopting more robust automated methods. Animal behaviour, 149, 89-95. doi:10.1016/j.anbehav.2019.01.003

Data reduction analyses such as principal components and exploratory factor analyses identify relationships within a set of potentially correlated variables, and cluster correlated variables into a smaller overall quantity of groupings. Because of th... Read More

The mechanical loading and muscle activation of four common exercises used in osteoporosis prevention for early postmenopausal women (2018)
Journal Article
Montgomery, G., Abt, G., Dobson, C., Smith, T., Evans, W., & Ditroilo, M. (2019). The mechanical loading and muscle activation of four common exercises used in osteoporosis prevention for early postmenopausal women. Journal of Electromyography and Kinesiology, 44, 124-131. doi:10.1016/j.jelekin.2018.12.004

High impact exercise can reduce postmenopausal bone loss, however stimulus frequency (loading cycles per second) can affect osteogenesis. We aimed to examine the effect of stimulus frequency on the mechanical loading of four comm... Read More

Effects of acute insulin-induced hypoglycaemia on endothelial microparticles in adults with and without type 2 diabetes (2018)
Journal Article
Al-Qaissi, A., Papageorgiou, M., Deshmukh, H., Madden, L. A., Rigby, A., Kilpatrick, E. S., …Sathyapalan, T. (2019). Effects of acute insulin-induced hypoglycaemia on endothelial microparticles in adults with and without type 2 diabetes. Diabetes, Obesity and Metabolism, 21(3), 533-540. doi:10.1111/dom.13548

Aims Endothelial microparticles (EMPs) are novel surrogate markers of endothelial injury and dysfunction that may be differentially produced in response to acute insulin‐induced hypoglycaemia in adults with and without type 2 diabetes.

Amplified antimicrobial action of chlorhexidine encapsulated in PDAC-functionalized acrylate copolymer nanogel carriers (2018)
Journal Article
Al-Awady, M. J., Weldrick, P. J., Hardman, M. J., Greenway, G. M., & Paunov, V. N. (2018). Amplified antimicrobial action of chlorhexidine encapsulated in PDAC-functionalized acrylate copolymer nanogel carriers. Materials Chemistry Frontiers, 2(11), 2032-2044. doi:10.1039/c8qm00343b

We have developed and tested a novel functionalised nanocarrier for chlorhexidine (CHX) which provides a very strong enhancement of its antimicrobial action. The nanocarrier was based on lightly-cross-linked acrylate copolymer nanogel particles loade... Read More

Relationships between walking speed, T-score and age with gait parameters in older post-menopausal women with low bone mineral density (2018)
Journal Article
Dostanpor, A., Dobson, C. A., & Vanicek, N. (2018). Relationships between walking speed, T-score and age with gait parameters in older post-menopausal women with low bone mineral density. Gait and Posture, 64, (230-237). doi:10.1016/j.gaitpost.2018.05.005. ISSN 0966-6362

Background: The gait patterns of women with low bone mineral density (BMD) or osteoporosis have not been thoroughly explored, and when examined, often studied in relation to falls and kyphosis. Research question: The aim of this study was to investig... Read More

Do predictive relationships exist between postural control and falls efficacy in unilateral transtibial prosthesis users? (2018)
Journal Article
Barnett, C. T., Vanicek, N., & Rusaw, D. F. (2018). Do predictive relationships exist between postural control and falls efficacy in unilateral transtibial prosthesis users?. Archives of physical medicine and rehabilitation, 99(11), 2271-2278. doi:10.1016/j.apmr.2018.05.016

Objective: To assess whether variables from a postural control test relate to and predict falls efficacy in prosthesis users. Design: Twelve-month within and between subjects repeated measures design. Participants performed the Limits of Stability... Read More

Synthesis, Crystal Structure, and Cytotoxicity Studies of titanacalix[4 and 8]arene Complexes (2018)
Journal Article
Miller-Shakesby, D. M., Nigam, S., Hughes, D. L., Lopez-Estelles, E., Elsegood, M. R., Cawthorne, C. J., …Redshaw, C. (2018). Synthesis, Crystal Structure, and Cytotoxicity Studies of titanacalix[4 and 8]arene Complexes. Dalton transactions : an international journal of inorganic chemistry / RSoC, 47(27), (8992-8999). doi:10.1039/c8dt01992d. ISSN 1477-9226

© 2018 The Royal Society of Chemistry. Reaction of 5,11,17,23-tetra-tert-butyl-dihydroxy-26,28-bis(2-pentoxy)calix[4]arene (L(OH)2(Opentyl)2) with [TiCl4] afforded the dichlorotitanoacalix[4]arene complex [TiCl2L(O)2(Opentyl)2] (1) in good yield. Hyd... Read More

Validity and reliability of a wearable inertial sensor to measure velocity and power in the back squat and bench press (2018)
Journal Article
Orange, S. T., Metcalfe, J. W., Liefeith, A., Marshall, P., Madden, L. A., Fewster, C. R., & Vince, R. V. (2018). Validity and reliability of a wearable inertial sensor to measure velocity and power in the back squat and bench press. Journal of strength and conditioning research, 1. doi:10.1519/jsc.0000000000002574

This study examined the validity and reliability of a wearable inertial sensor to measure velocity and power in the free-weight back squat and bench press. Twenty-nine youth rugby league players (18 ± 1 years) completed 2 test-retest sessions for the... Read More

A personalised exercise programme for individuals with lower limb amputation reduces falls and improves gait biomechanics: A block randomised controlled trial (2018)
Journal Article
Schafer, Z. A., Perry, J. L., & Vanicek, N. (2018). A personalised exercise programme for individuals with lower limb amputation reduces falls and improves gait biomechanics: A block randomised controlled trial. Gait and Posture, 63, 282-289. doi:10.1016/j.gaitpost.2018.04.030

Background: Lower limb amputees (LLAs) are at increased risk of falling due to the inherent asymmetry resulting from their limb loss, muscle weakness and other neuro-musculoskeletal limitations. Research question: The aim of this study was to evaluat... Read More

Thinking aloud: an exploration of cognitions in professional snooker (2018)
Journal Article
Welsh, J. C., Dewhurst, S. A., & Perry, J. L. (2018). Thinking aloud: an exploration of cognitions in professional snooker. Psychology of sport and exercise, 36, (197-208). doi:10.1016/j.psychsport.2018.03.003. ISSN 1469-0292

Objectives: Presently, there is no exploration into the cognitive processes of super-elite and elite professional snooker players during real-time performance. Therefore, this study explored the cognitions of seven professional snooker players during... Read More

The short-term training and detraining effects of supervised versus unsupervised resistance exercise in aging adults (2018)
Journal Article
Orange, S. T., Marshall, P., Madden, L. A., & Vince, R. V. (2018). The short-term training and detraining effects of supervised versus unsupervised resistance exercise in aging adults. Journal of strength and conditioning research, doi:10.1519/jsc.0000000000002536. ISSN 1064-8011

This study compared the effects of a 4-week supervised (SUP) and unsupervised (UNSUP) resistance training programme followed by 12 weeks of detraining (DET). Thirty-six healthy aging adults (age: 53.6 ± 3.6 years; body mass index: 28.3 ± 5.1 kg/m2) w... Read More

Interleukin-7 unveils Pathogen-Specific T Cells by enhancing Antigen-Recall responses (2018)
Journal Article
Terrazzini, N., Mantegani, P., Kern, F., Fortis, C., Mondino, A., & Caserta, S. (2018). Interleukin-7 unveils Pathogen-Specific T Cells by enhancing Antigen-Recall responses. The journal of infectious diseases : official publication of the Infectious Diseases Society of America, 217(12), 1997-2007. doi:10.1093/infdis/jiy096

© 2018 The Author(s). Background Interleukin (IL)-7 promotes the generation, expansion, and survival of memory T cells. Previous mouse and human studies showed that IL-7 can support immune cell reconstitution in lymphopenic conditions, expand tumor-r... Read More

Measuring Moderate-Intensity Exercise with the Apple Watch: Validation Study (2018)
Journal Article
Abt, G., Bray, J., & Benson, A. C. (in press). Measuring Moderate-Intensity Exercise with the Apple Watch: Validation Study. JMIR Cardio, 2(1), (e6). doi:10.2196/cardio.8574. ISSN 2561-1011

Background: Moderate fitness levels and habitual exercise have a protective effect for cardiovascular disease, stroke, type 2 diabetes, and all-cause mortality. The Apple Watch displays exercise completed at an intensity of a brisk walk or above usin... Read More

Severity of Systemic Inflammatory Response Syndrome Affects the Blood Levels of Circulating Inflammatory-Relevant MicroRNAs (2018)
Journal Article
Caserta, S., Mengozzi, M., Kern, F., Newbury, S. F., Ghezzi, P., & Llewelyn, M. J. (2018). Severity of Systemic Inflammatory Response Syndrome Affects the Blood Levels of Circulating Inflammatory-Relevant MicroRNAs. Frontiers in immunology, 8, doi:10.3389/fimmu.2017.01977

The systemic inflammatory response syndrome (SIRS) is a potentially lethal response triggered by diverse forms of tissue injury and infection. When systemic inflammation is triggered by infection, the term sepsis is used. Understanding how inflammati... Read More

Differing mechanisms of thrombin generation in live haematological and solid cancer cells determined by calibrated automated thrombography (2017)
Journal Article
Adesanya, M. A., Maraveyas, A., & Madden, L. (2017). Differing mechanisms of thrombin generation in live haematological and solid cancer cells determined by calibrated automated thrombography. Blood Coagulation and Fibrinolysis, 28(8), (602-611). doi:10.1097/mbc.0000000000000644. ISSN 0957-5235

© 2017 Wolters Kluwer Health, Inc. All rights reserved. Calibrated automated thrombography (CAT) is emerging as a reliable tool for real-Time estimation of thrombin generation potential. There is a clinical need for knowledge about the pathways under... Read More

Lck is a relevant target in chronic lymphocytic leukaemia cells whose expression variance is unrelated to disease outcome (2017)
Journal Article
Till, K. J., Allen, J. C., Talab, F., Lin, K., Allsup, D., Cawkwell, L., …Slupsky, J. R. (2017). Lck is a relevant target in chronic lymphocytic leukaemia cells whose expression variance is unrelated to disease outcome. Scientific reports, 7(1), doi:10.1038/s41598-017-17021-w. ISSN 2045-2322

© 2017 The Author(s). Pathogenesis of chronic lymphocytic leukaemia (CLL) is contingent upon antigen receptor (BCR) expressed by malignant cells of this disease. Studies on somatic hypermutation of the antigen binding region, receptor expression leve... Read More

The validity and inter-device variability of the Apple Watch™ for measuring maximal heart rate (2017)
Journal Article
Abt, G., Bray, J., & Benson, A. C. (2018). The validity and inter-device variability of the Apple Watch™ for measuring maximal heart rate. Journal of sports sciences, 36(13), 1447-1452. doi:10.1080/02640414.2017.1397282

Maximal heart rate (HRmax) is a fundamental measure used in exercise prescription. The Apple Watch measures heart rate yet the validity and inter-device variability of the device for measuring HRmax are unknown. Fifteen participants completed a maxim... Read More

A brighter future : the effect of positive episodic simulation on future predictions in non-depressed, moderately dysphoric & highly dysphoric individuals (2017)
Journal Article
Boland, J., Riggs, K. J., & Anderson, R. J. (2018). A brighter future : the effect of positive episodic simulation on future predictions in non-depressed, moderately dysphoric & highly dysphoric individuals. Behaviour Research and Therapy, 100, 7-16. doi:10.1016/j.brat.2017.10.010

Previous research suggests depressed individuals have difficulties with future directed cognitions. For instance, compared with non-depressed individuals, they predict positive events are less likely to occur. Recent work suggests that episodic simul... Read More

Measuring the response of human head and neck squamous cell carcinoma to irradiation in a microfluidic model allowing customized therapy (2017)
Journal Article
Cheah, R., Srivastava, R., Stafford, N. D., Beavis, A. W., Green, V., & Greenman, J. (2017). Measuring the response of human head and neck squamous cell carcinoma to irradiation in a microfluidic model allowing customized therapy. International Journal of Oncology, 51(4), (1227-1238). doi:10.3892/ijo.2017.4118. ISSN 1791-2423

Radiotherapy is the standard treatment for head and neck squamous cell carcinoma (HNSCC), however, radioresistance remains a major clinical problem despite significant improvements in treatment protocols. Therapeutic outcome could potentially be impr... Read More