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All Outputs (6)

Development of guidelines to reduce, handle and report missing data in palliative care trials: A multi-stakeholder modified nominal group technique (2022)
Journal Article
Hussain, J. A., White, I. R., Johnson, M. J., Byrne, A., Preston, N. J., Haines, A., …Peters, T. J. (2022). Development of guidelines to reduce, handle and report missing data in palliative care trials: A multi-stakeholder modified nominal group technique. Palliative medicine, 36(1), 59-70. https://doi.org/10.1177/02692163211065597

Background: Missing data can introduce bias and reduce the power, precision and generalisability of study findings. Guidelines on how to address missing data are limited in scope and detail, and poorly implemented. Aim: To develop guidelines on how b... Read More about Development of guidelines to reduce, handle and report missing data in palliative care trials: A multi-stakeholder modified nominal group technique.

Performance status and trial site-level factors are associated with missing data in palliative care trials: An individual participant-level data analysis of 10 phase 3 trials (2021)
Journal Article
Hussain, J. A., White, I. R., Johnson, M. J., Bland, M., & Currow, D. C. (2021). Performance status and trial site-level factors are associated with missing data in palliative care trials: An individual participant-level data analysis of 10 phase 3 trials. Palliative medicine, https://doi.org/10.1177/02692163211040970

Background: Missing data compromise the internal and external validity of trial findings, however there is limited evidence on how best to reduce missing data in palliative care trials. Aim: To assess the association between participant and site leve... Read More about Performance status and trial site-level factors are associated with missing data in palliative care trials: An individual participant-level data analysis of 10 phase 3 trials.

Specialist palliative care services response to ethnic minority groups with COVID-19: equal but inequitable—an observational study (2021)
Journal Article
Bajwah, S., Koffman, J., Hussain, J., Bradshaw, A., Hocaoglu, M. B., Fraser, L. K., …Murtagh, F. E. M. (2021). Specialist palliative care services response to ethnic minority groups with COVID-19: equal but inequitable—an observational study. BMJ Supportive & Palliative Care, bmjspcare-2021-003083. https://doi.org/10.1136/bmjspcare-2021-003083

Objectives: To develop insights into response of palliative care services caring for people from ethnic minority groups during COVID-19. Methods: Cross-sectional online survey of UK palliative care services response to COVID-19. Quantitative data w... Read More about Specialist palliative care services response to ethnic minority groups with COVID-19: equal but inequitable—an observational study.

Intention-to-treat analyses for randomised controlled trials in hospice/palliative care: the case for analyses to be of people exposed to the intervention. (2019)
Journal Article
Kochovska, S., Huang, C., Johnson, M. J., Agar, M. R., Fallon, M. T., Kaasa, S., …Currow, D. C. (2020). Intention-to-treat analyses for randomised controlled trials in hospice/palliative care: the case for analyses to be of people exposed to the intervention. Journal of pain and symptom management, 59(3), 637-645. https://doi.org/10.1016/j.jpainsymman.2019.10.026

© 2019 American Academy of Hospice and Palliative Medicine Context: Minimizing bias in randomized controlled trials (RCTs) includes intention-to-treat analyses. Hospice/palliative care RCTs are constrained by high attrition unpredictable when consent... Read More about Intention-to-treat analyses for randomised controlled trials in hospice/palliative care: the case for analyses to be of people exposed to the intervention..

A feasibility, randomised controlled trial of a complex breathlessness intervention in idiopathic pulmonary fibrosis (BREEZE-IPF): study protocol (2019)
Journal Article
Wright, C., Hart, S. P., Allgar, V., English, A., Swan, F., Dyson, J., …Crooks, M. G. (2019). A feasibility, randomised controlled trial of a complex breathlessness intervention in idiopathic pulmonary fibrosis (BREEZE-IPF): study protocol. ERJ Open Research, 5(4), Article 0186. https://doi.org/10.1183/23120541.00186-2019

Introduction: Idiopathic pulmonary fibrosis (IPF) is a chronic and progressive lung disease that causes breathlessness and cough that worsen over time, limiting daily activities and negatively impacting quality of life. Although treatments are now av... Read More about A feasibility, randomised controlled trial of a complex breathlessness intervention in idiopathic pulmonary fibrosis (BREEZE-IPF): study protocol.

Patient and health care professional decision-making to commence and withdraw from renal dialysis: A systematic review of qualitative research (2015)
Journal Article
Hussain, J. A., Flemming, K., Murtagh, F. E., & Johnson, M. J. (2015). Patient and health care professional decision-making to commence and withdraw from renal dialysis: A systematic review of qualitative research. Clinical journal of the American Society of Nephrology, 10(7), 1201-1215. https://doi.org/10.2215/cjn.11091114

Background and objectives. To ensure decisions to start and stop dialysis in end stage kidney disease are shared, the factors that affect patients and healthcare professionals in making such decisions need to be understood. This systematic review aim... Read More about Patient and health care professional decision-making to commence and withdraw from renal dialysis: A systematic review of qualitative research.