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Towards person-centred quality care for children with life-limiting and life-threatening illness: Self-reported symptoms, concerns and priority outcomes from a multi-country qualitative study (2020)
Journal Article
Namisango, E., Bristowe, K., Murtagh, F. E., Downing, J., Powell, R. A., Abas, M., …Harding, R. (in press). Towards person-centred quality care for children with life-limiting and life-threatening illness: Self-reported symptoms, concerns and priority outcomes from a multi-country qualitative study. Palliative medicine, https://doi.org/10.1177/0269216319900137

Background: Paediatric life-limiting and life-threatening conditions (life-limiting conditions) place significant strain on children, families and health systems. Given high service use among this population, it is essential that care addresses thei... Read More about Towards person-centred quality care for children with life-limiting and life-threatening illness: Self-reported symptoms, concerns and priority outcomes from a multi-country qualitative study.

The relationship between pain, analgesics and survival in patients with advanced cancer: a secondary data analysis of the international European palliative care cancer symptom study. (2019)
Journal Article
Boland, J. W., Allgar, V., Boland, E. G., Bennett, M. I., Kaasa, S., Hjermstad, M. J., & Johnson, M. (in press). The relationship between pain, analgesics and survival in patients with advanced cancer: a secondary data analysis of the international European palliative care cancer symptom study. European Journal of Clinical Pharmacology, https://doi.org/10.1007/s00228-019-02801-2

Purpose Opioids reduce cancer-related pain but an association with shorter survival is variably reported. Aim: To investigate the relationship between pain, analgesics, cancer and survival within the European Palliative Care Cancer Symptom (EPCCS) s... Read More about The relationship between pain, analgesics and survival in patients with advanced cancer: a secondary data analysis of the international European palliative care cancer symptom study..

Implementing pelvic floor muscle training in women's childbearing years: A critical interpretive synthesis of individual, professional, and service issues (2019)
Journal Article
Salmon, V. E., Hay‐Smith, E. J. C., Jarvie, R., Dean, S., Terry, R., Frawley, H., …Pearson, M. (in press). Implementing pelvic floor muscle training in women's childbearing years: A critical interpretive synthesis of individual, professional, and service issues. Neurourology and Urodynamics, https://doi.org/10.1002/nau.24256

Antenatal pelvic floor muscle training (PFMT) may be effective for the prevention and treatment of urinary and fecal incontinence both in pregnancy and postnatally, but it is not routinely implemented in practice despite guideline recommendations. Th... Read More about Implementing pelvic floor muscle training in women's childbearing years: A critical interpretive synthesis of individual, professional, and service issues.

Low-intensity educational interventions supporting self-management to improve outcomes related to chronic breathlessness: a systematic review (2019)
Journal Article
Raymond, B., Johnson, M., Luckett, T., Hutchinson, A., Lovell, M., & Phillips, J. (2019). Low-intensity educational interventions supporting self-management to improve outcomes related to chronic breathlessness: a systematic review. NPJ Primary Care Respiratory Medicine, 29, https://doi.org/10.1038/s41533-019-0152-8

Chronic breathlessness is debilitating and frightening, often resulting in emergency department presentations with acute-on-chronic breathlessness. Self-management is complex, involving 14 components as identified by the Practical Systematic Review i... Read More about Low-intensity educational interventions supporting self-management to improve outcomes related to chronic breathlessness: a systematic review.

No excess harms from sustained release morphine compared with placebo; findings from a placebo-controlled randomised trial in chronic breathlessness (2019)
Journal Article
Johnson, M. J., Sbizzera, I., Fairhurst, C., Fazekas, B., Agar, M. R., Ekström, M., & Currow, D. C. (in press). No excess harms from sustained release morphine compared with placebo; findings from a placebo-controlled randomised trial in chronic breathlessness. BMJ supportive & palliative care, https://doi.org/10.1136/bmjspcare-2019-002009

Objectives: We aimed to identify and evaluate i) treatment-emergent adverse events (TEAE [worse or new since baseline]) and the sub-group of severe TEAEs in a placebo-controlled seven-day randomised trial of regular, low-dose, sustained-release oral... Read More about No excess harms from sustained release morphine compared with placebo; findings from a placebo-controlled randomised trial in chronic breathlessness.

Intention-to-treat analyses for randomised controlled trials in hospice/palliative care: the case for analyses to be of people exposed to the intervention. (2019)
Journal Article
Currow, D. C., Higginson, I. J., Portenoy, R. K., Hussain, J. A., Kochovska, S., Huang, C., …Currow, D. C. (2019). Intention-to-treat analyses for randomised controlled trials in hospice/palliative care: the case for analyses to be of people exposed to the intervention. Journal of pain and symptom management, https://doi.org/10.1016/j.jpainsymman.2019.10.026

Introduction Minimising bias in randomised controlled trials (RCTs) includes intention-to-treat (ITT) analyses. Hospice/palliative care RCTs are constrained by high attrition unpredictable when consenting, including withdrawals between randomisati... Read More about Intention-to-treat analyses for randomised controlled trials in hospice/palliative care: the case for analyses to be of people exposed to the intervention..

The effects of opioids on cognition in older adults with cancer and chronic non-cancer pain: A systematic review (2019)
Journal Article
Pask, S., Dell’Olio, M., Murtagh, F. E., & Boland, J. W. (in press). The effects of opioids on cognition in older adults with cancer and chronic non-cancer pain: A systematic review. Journal of pain and symptom management, https://doi.org/10.1016/j.jpainsymman.2019.10.022

Context Opioids are prescribed to manage moderate to severe pain and can be used with older adults; however, they may lead to several adverse effects, including cognitive impairment. Objective To identify, appraise and synthesise evidence on i)... Read More about The effects of opioids on cognition in older adults with cancer and chronic non-cancer pain: A systematic review.

Palliative care in Parkinson’s disease: Review of needs assessment tools (2019)
Journal Article
Richfield, E., & Johnson, M. (in press). Palliative care in Parkinson’s disease: Review of needs assessment tools. Annals of palliative medicine, https://doi.org/10.21037/apm.2019.09.18

Palliative care in Parkinson’s disease (PD) has developed significantly in the past five years. The presence of unmet palliative care need, similar to that in malignant conditions, is well established, but may not always be identified by clinicians i... Read More about Palliative care in Parkinson’s disease: Review of needs assessment tools.

Breathlessness, anxiety, depression and function - the BAD-F study: a cross-sectional, population prevalence study in adults. (2019)
Journal Article
Currow, D. C., Chang, S., Reddel, H. K., Kochovska, S., Ferreira, D., Johnson, M., & Ekström, M. (in press). Breathlessness, anxiety, depression and function - the BAD-F study: a cross-sectional, population prevalence study in adults. Journal of pain and symptom management, https://doi.org/10.1016/j.jpainsymman.2019.09.021

Introduction Chronic breathlessness is associated with depression, but its relationship to anxiety is less clear. Objectives This study evaluated associations between chronic breathlessness and: anxiety; depression; functional status in the genera... Read More about Breathlessness, anxiety, depression and function - the BAD-F study: a cross-sectional, population prevalence study in adults..

A feasibility, randomised controlled trial of a complex breathlessness intervention in idiopathic pulmonary fibrosis (BREEZE-IPF): study protocol (2019)
Journal Article
Crooks, M. G., Wright, C., Hart, S. P., Allgar, V., English, A., Swan, F., …Crooks, M. G. (2019). A feasibility, randomised controlled trial of a complex breathlessness intervention in idiopathic pulmonary fibrosis (BREEZE-IPF): study protocol. ERJ Open Research, 5(4), https://doi.org/10.1183/23120541.00186-2019

Introduction: Idiopathic pulmonary fibrosis (IPF) is a chronic and progressive lung disease that causes breathlessness and cough that worsen over time, limiting daily activities and negatively impacting quality of life. Although treatments are now av... Read More about A feasibility, randomised controlled trial of a complex breathlessness intervention in idiopathic pulmonary fibrosis (BREEZE-IPF): study protocol.

What are the main symptoms and concerns reported by patients with advanced chronic heart failure?—a secondary analysis of the Palliative care Outcome Scale (POS) and Integrated Palliative care Outcome Scale (IPOS) (2019)
Journal Article
Kane, P., Dunleavy, L., Gadoud, A., Guo, P., Oriani, A., & Murtagh, F. E. (2019). What are the main symptoms and concerns reported by patients with advanced chronic heart failure?—a secondary analysis of the Palliative care Outcome Scale (POS) and Integrated Palliative care Outcome Scale (IPOS). Annals of palliative medicine, 8(5), 775-780. https://doi.org/10.21037/apm.2019.08.10

© Annals of Palliative Medicine. All rights reserved. There is a lack of valid disease-specific patient-reported outcome measures (PROMs) for detecting symptoms and concerns in patients with advanced chronic heart failure (CHF). The Palliative care O... Read More about What are the main symptoms and concerns reported by patients with advanced chronic heart failure?—a secondary analysis of the Palliative care Outcome Scale (POS) and Integrated Palliative care Outcome Scale (IPOS).

Mental wellbeing in bereaved carers: A Health Survey for England population study (2019)
Journal Article
Hodiamont, F., Allgar, V., Currow, D. C., & Johnson, M. J. (in press). Mental wellbeing in bereaved carers: A Health Survey for England population study. BMJ supportive & palliative care, https://doi.org/10.1136/bmjspcare-2019-001957

Objectives The experience of caregiving may affect carers’ well-being into bereavement. We explored associations between mental well-being and previous experience of bereavement of, and caring for, someone close at the end-of-life. Methods An end-... Read More about Mental wellbeing in bereaved carers: A Health Survey for England population study.

Improving the quality of life of people with advanced respiratory disease and severe breathlessness (2019)
Journal Article
Booth, S., & Johnson, M. J. (2019). Improving the quality of life of people with advanced respiratory disease and severe breathlessness. Breathe, 15(3), 198-215. https://doi.org/10.1183/20734735.0200-2019

Advanced respiratory disease (ARD) imposes a greater symptom burden than many cancers but without comparable recognition of the need for supportive and palliative care or the infrastructure for its systematic delivery. Consequently, many people with... Read More about Improving the quality of life of people with advanced respiratory disease and severe breathlessness.

Images depicting headache pain – a tool to aid the diagnosis of cluster headache: a pilot study (2019)
Journal Article
Buture, A., Boland, J. W., Ahmed, F., & Dikomitis, L. (2019). Images depicting headache pain – a tool to aid the diagnosis of cluster headache: a pilot study. Journal of Multidisciplinary Healthcare, 12, 691-698. https://doi.org/10.2147/jmdh.s207128

Introduction and objective: The diagnosis of primary headaches is based on the International Classification of Headache Disorders (ICHD-3). Cluster headache (CH), a debilitating primary headache, is often misdiagnosed as migraine. In the absence of b... Read More about Images depicting headache pain – a tool to aid the diagnosis of cluster headache: a pilot study.

Managing uncertain recovery for patients nearing the end of life in hospital: a mixed-methods feasibility cluster randomised controlled trial of the AMBER care bundle (2019)
Journal Article
Koffman, J., Yorganci, E., Yi, D., Gao, W., Murtagh, F., Pickles, A., …Evans, C. J. (2019). Managing uncertain recovery for patients nearing the end of life in hospital: a mixed-methods feasibility cluster randomised controlled trial of the AMBER care bundle. Trials, 20(1), https://doi.org/10.1186/s13063-019-3612-0

Background The AMBER (Assessment, Management, Best Practice, Engagement, Recovery Uncertain) care bundle is a complex intervention used in UK hospitals to support patients with uncertain recovery. However, it has yet to be evaluated in a randomised... Read More about Managing uncertain recovery for patients nearing the end of life in hospital: a mixed-methods feasibility cluster randomised controlled trial of the AMBER care bundle.

Oral modified release morphine for breathlessness in chronic heart failure: a randomised placebo-controlled trial (2019)
Journal Article
Johnson, M., Cockayne, S., Currow, D., Bell, K., Hicks, K., Fairhurst, C., …Clark, A. (in press). Oral modified release morphine for breathlessness in chronic heart failure: a randomised placebo-controlled trial. ESC Heart Failure, https://doi.org/10.1002/ehf2.12498

ABSTRACT Aims: Morphine is shown to relieve chronic breathless in chronic obstructive pulmonary disease. There are no definitive data in people with heart failure. We aimed to determine the effectiveness and cost-effectiveness of 12 weeks’ morphine... Read More about Oral modified release morphine for breathlessness in chronic heart failure: a randomised placebo-controlled trial.