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All Outputs (314)

Evaluating a web-based computer-tailored physical activity intervention for those living with and beyond lung cancer (ExerciseGuide UK): protocol for a single group feasibility and acceptability study (2022)
Journal Article
Curry, J., Lind, M., Short, C. E., Vandelanotte, C., Evans, H. E., Pearson, M., & Forbes, C. C. (2022). Evaluating a web-based computer-tailored physical activity intervention for those living with and beyond lung cancer (ExerciseGuide UK): protocol for a single group feasibility and acceptability study. Pilot and Feasibility Studies, 8(1), Article 182. https://doi.org/10.1186/s40814-022-01129-6

Background: Lung cancer is the leading cause of cancer-related death globally. Physical activity and exercise provide unequivocal benefits to those living with and beyond lung cancer. However, few of those living with and beyond cancer meet the natio... Read More about Evaluating a web-based computer-tailored physical activity intervention for those living with and beyond lung cancer (ExerciseGuide UK): protocol for a single group feasibility and acceptability study.

The association between socioeconomic position and the symptoms and concerns of hospital inpatients seen by specialist palliative care: Analysis of routinely collected patient data (2022)
Journal Article
Davies, J. M., Sleeman, K. E., Ramsenthaler, C., Prentice, W., Maddocks, M., & Murtagh, F. E. (2022). The association between socioeconomic position and the symptoms and concerns of hospital inpatients seen by specialist palliative care: Analysis of routinely collected patient data. Palliative medicine, https://doi.org/10.1177/02692163221115331

Background: Understanding how socioeconomic position influences the symptoms and concerns of patients approaching the end of life is important for planning more equitable care. Data on this relationship is lacking, particularly for patients with non-... Read More about The association between socioeconomic position and the symptoms and concerns of hospital inpatients seen by specialist palliative care: Analysis of routinely collected patient data.

Improving the Detection, Assessment, Management and Prevention of Delirium in Hospices (the DAMPen-D study): protocol for a co-design and feasibility study of a flexible and scalable implementation strategy to deliver guideline-adherent delirium care (2022)
Journal Article
Pearson, M., Jackson, G., Jackson, C., Boland, J., Featherstone, I., Huang, C., …Johnson, M. (2022). Improving the Detection, Assessment, Management and Prevention of Delirium in Hospices (the DAMPen-D study): protocol for a co-design and feasibility study of a flexible and scalable implementation strategy to deliver guideline-adherent delirium care. BMJ open, 12(7), Article e060450. https://doi.org/10.1136/bmjopen-2021-060450

INTRODUCTION: Delirium is a complex condition in which altered mental state and cognition causes severe distress and poor clinical outcomes for patients and families, anxiety and stress for the health professionals and support staff providing care, a... Read More about Improving the Detection, Assessment, Management and Prevention of Delirium in Hospices (the DAMPen-D study): protocol for a co-design and feasibility study of a flexible and scalable implementation strategy to deliver guideline-adherent delirium care.

Why do acute healthcare staff engage in unprofessional behaviours towards each other and how can these behaviours be reduced? A realist review protocol (2022)
Journal Article
Maben, J., Aunger, J., Abrams, R., Pearson, M., Wright, J., Westbrook, J., …Jones, A. (2022). Why do acute healthcare staff engage in unprofessional behaviours towards each other and how can these behaviours be reduced? A realist review protocol. BMJ open, 12(7), Article e061771. https://doi.org/10.1136/bmjopen-2022-061771

INTRODUCTION: Unprofessional behaviours encompass many behaviours including bullying, harassment and microaggressions. These behaviours between healthcare staff are problematic; they affect people's ability to work, to feel psychologically safe at wo... Read More about Why do acute healthcare staff engage in unprofessional behaviours towards each other and how can these behaviours be reduced? A realist review protocol.

Interrogating intervention delivery and participants’ emotional states to improve engagement and implementation: A realist informed multiple case study evaluation of Engager (2022)
Journal Article
Weston, L., Rybczynska-Bunt, S., Quinn, C., Lennox, C., Maguire, M., Pearson, M., …Byng, R. (2022). Interrogating intervention delivery and participants’ emotional states to improve engagement and implementation: A realist informed multiple case study evaluation of Engager. PLoS ONE, 17(7 July), Article e0270691. https://doi.org/10.1371/journal.pone.0270691

Background ‘Engager’ is an innovative ‘through-the-gate’ complex care intervention for male prison-leavers with common mental health problems. In parallel to the randomised-controlled trial of Engager (Trial registration number: ISRCTN11707331), a se... Read More about Interrogating intervention delivery and participants’ emotional states to improve engagement and implementation: A realist informed multiple case study evaluation of Engager.

The most important components of out-of-hours community care for patients at the end of life: A Delphi study of healthcare professionals’ and patient and family carers’ perspectives (2022)
Journal Article
Goodrich, J., Tutt, L., Firth, A. M., Evans, C. J., Murtagh, F. E., & Harding, R. (2022). The most important components of out-of-hours community care for patients at the end of life: A Delphi study of healthcare professionals’ and patient and family carers’ perspectives. Palliative medicine, https://doi.org/10.1177/02692163221106284

Background: Community services for palliative patients outside normal working hours are variable and the best evidence-based models of care have not been determined. Aim: To establish expert consensus on the most important components of out-of-hours... Read More about The most important components of out-of-hours community care for patients at the end of life: A Delphi study of healthcare professionals’ and patient and family carers’ perspectives.

Symptom Control and Survival for People Severely ill With COVID: A Multicentre Cohort Study (CovPall-Symptom) (2022)
Journal Article
Higginson, I. J., Hocaoglu, M., Fraser, L. K., Maddocks, M., Sleeman, K. E., Oluyase, A. O., …On behalf of theCovPall study team. (2022). Symptom Control and Survival for People Severely ill With COVID: A Multicentre Cohort Study (CovPall-Symptom). Journal of pain and symptom management, 64(4), 377-390. https://doi.org/10.1016/j.jpainsymman.2022.06.009

Context: Evidence of symptom control outcomes in severe COVID is scant. Objectives: To determine changes in symptoms among people severely ill or dying with COVID supported by palliative care, and associations with treatments and survival. Methods: M... Read More about Symptom Control and Survival for People Severely ill With COVID: A Multicentre Cohort Study (CovPall-Symptom).

Substituting bouts of sedentary behavior with physical activity: adopting positive lifestyle choices in people with a history of cancer (2022)
Journal Article
Ingle, L., Ruilova, S., Cui, Y., DeClercq, V., Sweeney, E., Yu, Z. M., & Forbes, C. C. (2022). Substituting bouts of sedentary behavior with physical activity: adopting positive lifestyle choices in people with a history of cancer. Cancer Causes and Control, https://doi.org/10.1007/s10552-022-01592-9

Purpose: To determine in people with a history of cancer, whether substituting sitting time with other daily activities (i.e., sleeping, walking, moderate and vigorous physical activity) was associated with changes in waist circumference (WC), an imp... Read More about Substituting bouts of sedentary behavior with physical activity: adopting positive lifestyle choices in people with a history of cancer.

Comparing recalled versus experienced symptoms of breathlessness ratings: An ecological assessment study using mobile phone technology (2022)
Journal Article
Sandberg, J., Sundh, J., Anderberg, P., Currow, D. C., Johnson, M., Lansing, R., & Ekström, M. (2022). Comparing recalled versus experienced symptoms of breathlessness ratings: An ecological assessment study using mobile phone technology. Respirology : official journal of the Asian Pacific Society of Respirology, https://doi.org/10.1111/resp.14313

Background and objective: Recall of breathlessness is important for clinical care but might differ from the experienced (momentary) symptoms. This study aimed to characterize the relationship between momentary breathlessness ratings and the recall of... Read More about Comparing recalled versus experienced symptoms of breathlessness ratings: An ecological assessment study using mobile phone technology.

Face and content validity, acceptability, feasibility, and implementability of a novel outcome measure for children with life-limiting or life-threatening illness in three sub-Saharan African countries (2022)
Journal Article
Namisango, E., Bristowe, K., Murtagh, F. E., Downing, J., Powell, R. A., Atieno, M., …Harding, R. (2022). Face and content validity, acceptability, feasibility, and implementability of a novel outcome measure for children with life-limiting or life-threatening illness in three sub-Saharan African countries. Palliative medicine, 36(7), 1140-1153. https://doi.org/10.1177/02692163221099583

Background: The Children’s Palliative Care Outcome Scale (C-POS) is the first measure developed for children with life-limiting and -threatening illness. It is essential to determine whether the measure addresses what matters to children, and if they... Read More about Face and content validity, acceptability, feasibility, and implementability of a novel outcome measure for children with life-limiting or life-threatening illness in three sub-Saharan African countries.

Tumour-Associated Tissue Factor (TF)-mRNA Is A Precursor for Rapid TF-Microvesicle Release and A Potential Predictive Marker for the Risk of Pulmonary Embolism (PE) in Gastrointestinal Cancer Patients (2022)
Journal Article
Ettelaie, C., Benelhaj, N., Featherby, S., Haque, F., Johnson, M., Cooke, J., & Maraveyas, A. (2022). Tumour-Associated Tissue Factor (TF)-mRNA Is A Precursor for Rapid TF-Microvesicle Release and A Potential Predictive Marker for the Risk of Pulmonary Embolism (PE) in Gastrointestinal Cancer Patients. Journal of Biotechnology and Biomedicine, 5(2), 78-93. https://doi.org/10.26502/jbb.2642-280050

Predicting which cancer patients are at risk of thrombosis remains a key challenge to effective thromboprophylaxis. This study was based on the hypothesis that the rapid release of TF-containing MV occurs in cancer cells that possess high levels of T... Read More about Tumour-Associated Tissue Factor (TF)-mRNA Is A Precursor for Rapid TF-Microvesicle Release and A Potential Predictive Marker for the Risk of Pulmonary Embolism (PE) in Gastrointestinal Cancer Patients.

Persisting breathlessness and activities reduced or ceased: a population study in older men (2022)
Journal Article
Kochovska, S., Currow, D., Chang, S., Johnson, M., Ferreira, D., Morgan, D., …Ekström, M. (2022). Persisting breathlessness and activities reduced or ceased: a population study in older men. BMJ Open Respiratory Research, 9(1), Article e001168. https://doi.org/10.1136/bmjresp-2021-001168

INTRODUCTION: Breathlessness is debilitating and increases in prevalence with age, with people progressively reducing their everyday activities to 'self-manage' it. This study aimed to evaluate the impact of breathlessness on function in terms of act... Read More about Persisting breathlessness and activities reduced or ceased: a population study in older men.

Implementing the battery-operated hand-held fan as an evidence-based, non-pharmacological intervention for chronic breathlessness in patients with chronic obstructive pulmonary disease (COPD): a qualitative study of the views of specialist respiratory clinicians (2022)
Journal Article
Luckett, T., Roberts, M., Smith, T., Garcia, M., Dunn, S., Swan, F., …Johnson, M. J. (2022). Implementing the battery-operated hand-held fan as an evidence-based, non-pharmacological intervention for chronic breathlessness in patients with chronic obstructive pulmonary disease (COPD): a qualitative study of the views of specialist respiratory clinicians. BMC Pulmonary Medicine, 22(1), Article 129. https://doi.org/10.1186/s12890-022-01925-z

INTRODUCTION: The battery-operated hand-held fan ('fan') is an inexpensive and portable non-pharmacological intervention for chronic breathlessness. Evidence from randomised controlled trials suggests the fan reduces breathlessness intensity and impr... Read More about Implementing the battery-operated hand-held fan as an evidence-based, non-pharmacological intervention for chronic breathlessness in patients with chronic obstructive pulmonary disease (COPD): a qualitative study of the views of specialist respiratory clinicians.

Lower workforce participation is associated with more severe persisting breathlessness (2022)
Journal Article
Clark, J., Chang, S., Kinchin, I., Ferreira, D., Kochovska, S., Morgan, D., …Currow, D. C. (2022). Lower workforce participation is associated with more severe persisting breathlessness. BMC Pulmonary Medicine, 22(1), Article 93. https://doi.org/10.1186/s12890-022-01861-y

Background: Not being able to work has negative health, social and financial consequences. Persisting breathlessness is prevalent in working-aged people. Is it associated with lower workforce participation? This study, using the South Australian Heal... Read More about Lower workforce participation is associated with more severe persisting breathlessness.

COVID-19: Impact on Pediatric Palliative Care (2022)
Journal Article
Scott, H. M., Coombes, L., Braybrook, D., Roach, A., Harðardóttir, D., Bristowe, K., …Harding, R. (in press). COVID-19: Impact on Pediatric Palliative Care. Journal of pain and symptom management, https://doi.org/10.1016/j.jpainsymman.2022.02.330

Context: Children and young people with life-limiting or life-threatening conditions and their families are potentially vulnerable during COVID-19 lockdowns due to pre-existing high clinical support needs and social participation limitations. Objecti... Read More about COVID-19: Impact on Pediatric Palliative Care.

Towards codesign in respiratory care: development of an implementation-ready intervention to improve guideline-adherent adult asthma care across primary and secondary care settings (The SENTINEL Project) (2022)
Journal Article
Crowther, L., Pearson, M., Cummings, H., & Crooks, M. G. (2022). Towards codesign in respiratory care: development of an implementation-ready intervention to improve guideline-adherent adult asthma care across primary and secondary care settings (The SENTINEL Project). BMJ Open Respiratory Research, 9(1), Article e001155. https://doi.org/10.1136/bmjresp-2021-001155

Short-acting beta agonist (SABA) overuse (≥3 canisters annually) is associated with worse asthma outcomes and accounts for the majority of greenhouse gas emissions from asthma inhalers in England. Reducing SABA overuse aligns with the National Health... Read More about Towards codesign in respiratory care: development of an implementation-ready intervention to improve guideline-adherent adult asthma care across primary and secondary care settings (The SENTINEL Project).

Experiences of staff providing specialist palliative care during COVID-19: a multiple qualitative case study (2022)
Journal Article
Bradshaw, A., Dunleavy, L., Garner, I., Preston, N., Bajwah, S., Cripps, R., …CovPall study team. (in press). Experiences of staff providing specialist palliative care during COVID-19: a multiple qualitative case study. Journal of the Royal Society of Medicine, https://doi.org/10.1177/01410768221077366

Objective: To explore the experiences of, and impact on, staff working in palliative care during the COVID-19 pandemic. Design: Qualitative multiple case study using semi-structured interviews between November 2020 and April 2021 as part of the CovPa... Read More about Experiences of staff providing specialist palliative care during COVID-19: a multiple qualitative case study.

Conceptualising effective symptom management in palliative care: a novel model derived from qualitative data (2022)
Journal Article
Chapman, E. J., Pini, S., Edwards, Z., Elmokhallalati, Y., Murtagh, F. E., & Bennett, M. I. (2022). Conceptualising effective symptom management in palliative care: a novel model derived from qualitative data. BMC Palliative Care, 21(1), Article 17. https://doi.org/10.1186/s12904-022-00904-9

BACKGROUND: Pain, breathlessness and fatigue are some of the most challenging symptoms to manage in patients with advanced disease. Specialist palliative care leads to better symptom management, but factors contributing to successful symptom manageme... Read More about Conceptualising effective symptom management in palliative care: a novel model derived from qualitative data.

Concurrent validity and prognostic utility of the Needs Assessment Tool: Progressive Disease Heart Failure (2022)
Journal Article
King, C., Khamis, A., Ross, J., Murtagh, F. E., Johnson, M. J., & Ramsenthaler, C. (in press). Concurrent validity and prognostic utility of the Needs Assessment Tool: Progressive Disease Heart Failure. Journal of pain and symptom management, https://doi.org/10.1016/j.jpainsymman.2022.01.014

Context: People with advanced heart failure have supportive and palliative needs requiring systematic assessment. Objectives: We aimed to assess the validity of the Needs Assessment Tool: Progressive Disease – Heart Failure (NAT:PD-HF). Methods: Seco... Read More about Concurrent validity and prognostic utility of the Needs Assessment Tool: Progressive Disease Heart Failure.

Do guidelines influence breathlessness management in advanced lung diseases? A multinational survey of respiratory medicine and palliative care physicians (2022)
Journal Article
Krajnik, M., Hepgul, N., Wilcock, A., Jassem, E., Bandurski, T., Tanzi, S., …Walker, F. (2022). Do guidelines influence breathlessness management in advanced lung diseases? A multinational survey of respiratory medicine and palliative care physicians. BMC Pulmonary Medicine, 22(1), Article 41. https://doi.org/10.1186/s12890-022-01835-0

Background: Respiratory medicine (RM) and palliative care (PC) physicians’ management of chronic breathlessness in advanced chronic obstructive pulmonary disease (COPD), fibrotic interstitial lung disease (fILD) and lung cancer (LC), and the influenc... Read More about Do guidelines influence breathlessness management in advanced lung diseases? A multinational survey of respiratory medicine and palliative care physicians.