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All Outputs (4)

A novel hybrid SCCmec-mecC region in Staphylococcus sciuri (2013)
Journal Article
Harrison, E. M., Paterson, G. K., Holden, M. T. G., Ba, X., Rolo, J., Morgan, F. J. E., …Holmes, M. A. (2014). A novel hybrid SCCmec-mecC region in Staphylococcus sciuri. The journal of antimicrobial chemotherapy, 69(4), 911-918. https://doi.org/10.1093/jac/dkt452

Objectives Methicillin resistance in Staphylococcus spp. results from the expression of an alternative penicillin-binding protein 2a (encoded by mecA) with a low affinity for β-lactam antibiotics. Recently, a novel variant of mecA known as mecC (form... Read More about A novel hybrid SCCmec-mecC region in Staphylococcus sciuri.

Prevalence and characterization of human mecC methicillin-resistant Staphylococcus aureus isolates in England (2013)
Journal Article
Paterson, G. K., Morgan, F. J. E., Harrison, E. M., Cartwright, E. J. P., Török, M. E., Zadoks, R. N., …Holmes, M. A. (2014). Prevalence and characterization of human mecC methicillin-resistant Staphylococcus aureus isolates in England. The journal of antimicrobial chemotherapy, 69(4), 907-910. https://doi.org/10.1093/jac/dkt462

Objectives There are limited data available on the epidemiology and prevalence of methicillin-resistant Staphylococcus aureus (MRSA) in the human population that encode the recently described mecA homologue, mecC. To address this knowledge gap we und... Read More about Prevalence and characterization of human mecC methicillin-resistant Staphylococcus aureus isolates in England.

Novel mutations in penicillin-binding protein genes in clinical Staphylococcus aureus isolates that are methicillin resistant on susceptibility testing, but lack the mec gene (2013)
Journal Article
Ba, X., Harrison, E. M., Edwards, G. F., Holden, M. T., Larsen, A. R., Petersen, A., …Holmes, M. A. (2014). Novel mutations in penicillin-binding protein genes in clinical Staphylococcus aureus isolates that are methicillin resistant on susceptibility testing, but lack the mec gene. The journal of antimicrobial chemotherapy, 69(3), 594-597. https://doi.org/10.1093/jac/dkt418

Objectives: Methicillin-resistant Staphylococcus aureus (MRSA) is an important global health problem. MRSA resistance to β-lactam antibiotics is mediated by the mecA or mecC genes, which encode an alternative penicillin binding protein (PBP)2a that h... Read More about Novel mutations in penicillin-binding protein genes in clinical Staphylococcus aureus isolates that are methicillin resistant on susceptibility testing, but lack the mec gene.

Prevalence and properties of mecC methicillin-resistant Staphylococcus aureus (MRSA) in bovine bulk tank milk in Great Britain (2013)
Journal Article
Paterson, G. K., Morgan, F. J. E., Harrison, E. M., Peacock, S. J., Parkhill, J., Zadoks, R. N., & Holmes, M. A. (2014). Prevalence and properties of mecC methicillin-resistant Staphylococcus aureus (MRSA) in bovine bulk tank milk in Great Britain. The journal of antimicrobial chemotherapy, 69(3), 598-602. https://doi.org/10.1093/jac/dkt417

Objectives mecC methicillin-resistant Staphylococcus aureus (MRSA) represent a newly recognized form of MRSA, distinguished by the possession of a divergent mecA homologue, mecC. The first isolate to be identified came from bovine milk, but there are... Read More about Prevalence and properties of mecC methicillin-resistant Staphylococcus aureus (MRSA) in bovine bulk tank milk in Great Britain.