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Replication stress and chromatin context link ATM activation to a role in DNA replication (2013)
Journal Article
Olcina, M. M., Foskolou, I. P., Anbalagan, S., Senra, J. M., Pires, I. M., Jiang, Y., …Hammond, E. M. (2013). Replication stress and chromatin context link ATM activation to a role in DNA replication. Molecular cell, 52(5), 758-766. https://doi.org/10.1016/j.molcel.2013.10.019

ATM-mediated signaling in response to DNA damage is a barrier to tumorigenesis. Here we asked whether replication stress could also contribute to ATM signaling. We demonstrate that, in the absence of DNA damage, ATM responds to replication stress in... Read More about Replication stress and chromatin context link ATM activation to a role in DNA replication.

Use of the xCELLigence system for real-time analysis of changes in cellular motility and adhesion in physiological conditions (2013)
Journal Article
Scrace, S., O'Neill, E., Hammond, E. M., & Pires, I. M. (2013). Use of the xCELLigence system for real-time analysis of changes in cellular motility and adhesion in physiological conditions. Methods in molecular biology, 1046, 295-306. https://doi.org/10.1007/978-1-62703-538-5_17

Investigation of the mechanisms behind the regulation of cellular motility and adhesion is key to understanding metastasis and the biology of tumor spreading. There are many technologies available for these studies, but the majority of them are eithe... Read More about Use of the xCELLigence system for real-time analysis of changes in cellular motility and adhesion in physiological conditions.