Ligation of anti-cancer drugs to self-assembling ultrashort peptides by click chemistry for localized therapy
(2013)
Journal Article
Reithofer, M. R., Chan, K., Lakshmanan, A., Lam, D. H., Mishra, A., Gopalan, B., …Hauser, C. A. E. (2014). Ligation of anti-cancer drugs to self-assembling ultrashort peptides by click chemistry for localized therapy. Chemical science, 5(2), 625-630. https://doi.org/10.1039/c3sc51930a
Self-assembling ultrashort peptides from aliphatic amino acids were functionalized with platinum anti-cancer drugs by click chemistry. Oxaliplatin-derived hybrid peptide hydrogels with up to 40% drug loading were tested for localized breast cancer th... Read More about Ligation of anti-cancer drugs to self-assembling ultrashort peptides by click chemistry for localized therapy.