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All Outputs (3)

A new perspective of the structural complexity of HCMV-specific T-cell responses (2016)
Journal Article
Sylwester, A., Nambiar, K. Z., Caserta, S., Klenerman, P., Picker, L. J., & Kern, F. (2016). A new perspective of the structural complexity of HCMV-specific T-cell responses. Mechanisms of ageing and development, 158, 14-22. https://doi.org/10.1016/j.mad.2016.03.002

© 2016 The Authors Background In studies exploring the effects of HCMV infection on immune system aging (‘immunosenescence’), after organ transplantation or in other settings, HCMV-specific T-cell responses are often assessed with respect to purporte... Read More about A new perspective of the structural complexity of HCMV-specific T-cell responses.

Functional diversity of cytomegalovirus-specific T cells is maintained in older people and significantly associated with protein specificity and response size (2016)
Journal Article
Bajwa, M., Vita, S., Vescovini, R., Larsen, M., Sansoni, P., Terrazzini, N., …Kern, F. (2016). Functional diversity of cytomegalovirus-specific T cells is maintained in older people and significantly associated with protein specificity and response size. The journal of infectious diseases : official publication of the Infectious Diseases Society of America, 214(9), 1430-1437. https://doi.org/10.1093/infdis/jiw371

© The Author 2016. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. Background. Parallel upregulation of several T-cell effector functions (ie, polyfunctionality) is believed to be critical for... Read More about Functional diversity of cytomegalovirus-specific T cells is maintained in older people and significantly associated with protein specificity and response size.

Circulating plasma microRNAs can differentiate Human Sepsis and Systemic Inflammatory Response Syndrome (SIRS) (2016)
Journal Article
Caserta, S., Kern, F., Cohen, J., Drage, S., Newbury, S. F., & Llewelyn, M. J. (2016). Circulating plasma microRNAs can differentiate Human Sepsis and Systemic Inflammatory Response Syndrome (SIRS). Scientific reports, 6(1), Article 28006. https://doi.org/10.1038/srep28006

Systemic inflammation in humans may be triggered by infection, termed sepsis, or non-infective processes, termed non-infective systemic inflammatory response syndrome (SIRS). MicroRNAs regulate cellular processes including inflammation and may be det... Read More about Circulating plasma microRNAs can differentiate Human Sepsis and Systemic Inflammatory Response Syndrome (SIRS).