All Outputs (790)

Plant-expressed hepatitis B core antigen virus-like particles : characterization and investigation of their stability in simulated and pig gastro-intestinal fluids (2017)
Journal Article
Berardi, A., Lomonossoff, G. P., Evans, D. J., & Barker, S. A. (2017). Plant-expressed hepatitis B core antigen virus-like particles : characterization and investigation of their stability in simulated and pig gastro-intestinal fluids. International Journal of Pharmaceutics, 522(1-2), 147-156. https://doi.org/10.1016/j.ijpharm.2017.03.001

Virus-like particles (VLPs) are potential oral vaccine candidates, as their highly compact structure may allow them to withstand the harsh conditions of the gastro-intestinal (GI) environment. Hepatitis B core antigen (HBcAg) is an immunogenic protei... Read More about Plant-expressed hepatitis B core antigen virus-like particles : characterization and investigation of their stability in simulated and pig gastro-intestinal fluids.

Novel non-invasive algorithm to identify the origins of re-entry and ectopic foci in the atria from 64-lead ECGs. A computational study (2017)
Journal Article
Alday, E. A. P., Colman, M. A., Langley, P., & Zhang, H. (2017). Novel non-invasive algorithm to identify the origins of re-entry and ectopic foci in the atria from 64-lead ECGs. A computational study. PLoS Computational Biology, 13(3), e1005270. https://doi.org/10.1371/journal.pcbi.1005270

Atrial tachy-arrhytmias, such as atrial fibrillation (AF), are characterised by irregular electrical activity in the atria, generally associated with erratic excitation underlain by re-entrant scroll waves, fibrillatory conduction of multiple wavelet... Read More about Novel non-invasive algorithm to identify the origins of re-entry and ectopic foci in the atria from 64-lead ECGs. A computational study.

Patterns and persistence of behavioural and psychological symptoms in those with cognitive impairment: the importance of apathy (2017)
Journal Article
van der Linde, R. M., Matthews, F. E., Dening, T., & Brayne, C. (2017). Patterns and persistence of behavioural and psychological symptoms in those with cognitive impairment: the importance of apathy. International journal of geriatric psychiatry, 32(3), 306-315. https://doi.org/10.1002/gps.4464

Objective: To study the stability and emergence of a range of behavioural and psychological symptoms (BPS), their association with mortality and the effect of covariates on these transitions in a population-based study of cognitively impaired older p... Read More about Patterns and persistence of behavioural and psychological symptoms in those with cognitive impairment: the importance of apathy.

Association of delirium with cognitive decline in late life: A neuropathologic study of 3 population-based cohort studies (2017)
Journal Article
Davis, D. H., Muniz-Terrera, G., Keage, H. A., Stephan, B. C., Fleming, J., Ince, P. G., …Oinas, M. (2017). Association of delirium with cognitive decline in late life: A neuropathologic study of 3 population-based cohort studies. JAMA Psychiatry, 74(3), 244-251. https://doi.org/10.1001/jamapsychiatry.2016.3423

Importance: Delirium is associated with accelerated cognitive decline. The pathologic substrates of this association are not yet known, that is, whether they are the same as those associated with dementia, are independent, or are interrelated. Object... Read More about Association of delirium with cognitive decline in late life: A neuropathologic study of 3 population-based cohort studies.

Potentially modifiable lifestyle factors, cognitive reserve, and cognitive function in later life: A cross-sectional study (2017)
Journal Article
Clare, L., Wu, Y. T., Teale, J. C., MacLeod, C., Matthews, F., Brayne, C., & Woods, B. (2017). Potentially modifiable lifestyle factors, cognitive reserve, and cognitive function in later life: A cross-sectional study. PLoS Medicine, 14(3), https://doi.org/10.1371/journal.pmed.1002259

Background: Potentially modifiable lifestyle factors may influence cognitive health in later life and offer potential to reduce the risk of cognitive decline and dementia. The concept of cognitive reserve has been proposed as a mechanism to explain i... Read More about Potentially modifiable lifestyle factors, cognitive reserve, and cognitive function in later life: A cross-sectional study.

Dementia incidence trend over 1992-2014 in the Netherlands: Analysis of primary care data (2017)
Journal Article
van Bussel, E. F., Richard, E., Arts, D. L., Nooyens, A. C., Coloma, P. M., de Waal, M. W., …Moll van Charante, E. P. (2017). Dementia incidence trend over 1992-2014 in the Netherlands: Analysis of primary care data. PLoS Medicine, 14(3), https://doi.org/10.1371/journal.pmed.1002235

Background: Recent reports have suggested declining age-specific incidence rates of dementia in high-income countries over time. Improved education and cardiovascular health in early age have been suggested to be bringing about this effect. The aim o... Read More about Dementia incidence trend over 1992-2014 in the Netherlands: Analysis of primary care data.

Age-related cognitive decline and associations with sex, education and apolipoprotein E genotype across ethnocultural groups and geographic regions: a collaborative cohort study (2017)
Journal Article
Lipnicki, D. M., Crawford, J. D., Dutta, R., Thalamuthu, A., Kochan, N. A., Andrews, G., …Sachdev, P. S. (2017). Age-related cognitive decline and associations with sex, education and apolipoprotein E genotype across ethnocultural groups and geographic regions: a collaborative cohort study. PLoS Medicine, 14(3), https://doi.org/10.1371/journal.pmed.1002261

Background: The prevalence of dementia varies around the world, potentially contributed to by international differences in rates of age-related cognitive decline. Our primary goal was to investigate how rates of age-related decline in cognitive test... Read More about Age-related cognitive decline and associations with sex, education and apolipoprotein E genotype across ethnocultural groups and geographic regions: a collaborative cohort study.

Assessing reading development through systematic synthetic phonics (2017)
Journal Article
Glazzard, J. (2017). Assessing reading development through systematic synthetic phonics. English in Education, 51(1), 44-57. https://doi.org/10.1111/eie.12125

This narrative literature review evaluates the effectiveness of synthetic phonics in comparison with analytic phonics. It presents the key research findings and offers a critical appraisal of this research. Primary schools have developed a variety of... Read More about Assessing reading development through systematic synthetic phonics.

Localized tissue mineralization regulated by bone remodelling: A computational approach (2017)
Journal Article
Berli, M., Borau, C., Decco, O., Adams, G., Cook, R. B., Aznar, J. M. G., & Zioupos, P. (2017). Localized tissue mineralization regulated by bone remodelling: A computational approach. PLoS ONE, 12(3), Article e0173228. https://doi.org/10.1371/journal.pone.0173228

Bone is a living tissue whose main mechanical function is to provide stiffness, strength and protection to the body. Both stiffness and strength depend on the mineralization of the organic matrix, which is constantly being remodelled by the coordinat... Read More about Localized tissue mineralization regulated by bone remodelling: A computational approach.

Does early intervention improve outcomes in physiotherapy management of lumbar radicular syndrome? A mixed-methods study protocol (2017)
Journal Article
Reddington, M., Walters, S. J., Cohen, J., & Baxter, S. (2017). Does early intervention improve outcomes in physiotherapy management of lumbar radicular syndrome? A mixed-methods study protocol. BMJ open, 7(3), Article e014422. https://doi.org/10.1136/bmjopen-2016-014422

© Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-And-licensing/. Introduction Lumbar radicular syndrome (LRS) can be a... Read More about Does early intervention improve outcomes in physiotherapy management of lumbar radicular syndrome? A mixed-methods study protocol.

Ultra-stable self-foaming oils (2017)
Journal Article
Binks, B. P., & Marinopoulos, I. (2017). Ultra-stable self-foaming oils. Food Research International, 95, 28-37. https://doi.org/10.1016/j.foodres.2017.02.020

This paper is concerned with the foaming of a range of fats in the absence of added foaming agent/emulsifier. By controlling the temperature on warming from the solid or cooling from the melt, crystals of high melting triglycerides form in a continuo... Read More about Ultra-stable self-foaming oils.

TRPV1 polymorphisms influence capsaicin cough sensitivity in men (2017)
Journal Article
Sadofsky, L. R., Cantero-Recasens, G., Wright, C., Valverde, M. A., & Morice, A. H. (2017). TRPV1 polymorphisms influence capsaicin cough sensitivity in men. Journal of thoracic disease, 9(3), 839-840. https://doi.org/10.21037/jtd.2017.03.50

Capsaicin, the hot component of chilli peppers, is a well-known tussive agent, which is regularly used as a tool to study cough and antitussives (1). Capsaicin is known to activate the transient receptor potential vanilloid 1 (TRPV1) cation channel w... Read More about TRPV1 polymorphisms influence capsaicin cough sensitivity in men.

Primary somatosensory cortex necessary for the perception of weight from other people's action: a continuous theta-burst TMS experiment (2017)
Journal Article
Valchev, N., Tidoni, E., Hamilton, A. F. D. C., Gazzola, V., & Avenanti, A. (2017). Primary somatosensory cortex necessary for the perception of weight from other people's action: a continuous theta-burst TMS experiment. NeuroImage, 152, 195-206. https://doi.org/10.1016/j.neuroimage.2017.02.075

The presence of a network of areas in the parietal and premotor cortices, which are active both during action execution and observation, suggests that we might understand the actions of other people by activating those motor programs for making simil... Read More about Primary somatosensory cortex necessary for the perception of weight from other people's action: a continuous theta-burst TMS experiment.

Free trade as a force of political stability? The case of mainland China and Hong Kong (2017)
Journal Article
Villalta Puig, G., & Chan, V. (2017). Free trade as a force of political stability? The case of mainland China and Hong Kong. International Lawyer, 49(3), 299-323

Is free trade a force of political stability? This article argues that, while political stability could be a cause, it is not always a consequence of free trade. To test this argument, the article analyses the political causes and consequences of the... Read More about Free trade as a force of political stability? The case of mainland China and Hong Kong.

Facilitating permeability of landscapes impacted by roads for protected amphibians: patterns of movement for the great crested newt (2017)
Journal Article
Matos, C., Petrovan, S., Ward, A. I., & Wheeler, P. (2017). Facilitating permeability of landscapes impacted by roads for protected amphibians: patterns of movement for the great crested newt. PeerJ, 2017(2), e2922. https://doi.org/10.7717/peerj.2922

Amphibian populations are highly vulnerable to road mortality and habitat fragmentation caused by road networks. Wildlife road tunnels are considered the most promising road mitigation measure for amphibians yet generally remain inadequately monitore... Read More about Facilitating permeability of landscapes impacted by roads for protected amphibians: patterns of movement for the great crested newt.

Scour holes and ripples occur below the hydraulic smooth to rough transition of movable beds (2017)
Journal Article
Leuven, J. R., Kleinhans, M. G., Leuven, J. R. F. W., Braat, L., & Baar, A. (2017). Scour holes and ripples occur below the hydraulic smooth to rough transition of movable beds. Sedimentology, 64(5), 1381-1401. https://doi.org/10.1111/sed.12358

© 2017 The Authors. Scour holes often form in shallow flows over sand on the beach and in morphodynamic scale experiments of river reaches, deltas and estuarine landscapes. The scour holes are on average 2cm deep and 5cm long, regardless of the flow... Read More about Scour holes and ripples occur below the hydraulic smooth to rough transition of movable beds.

Implementing a mentor support system for general practice nurse mentors (2017)
Journal Article
Chambers, A., Smith, D., & Billingham, L. (2017). Implementing a mentor support system for general practice nurse mentors. Primary Health Care, 27(2), 21-25. https://doi.org/10.7748/phc.2017.e1216

This article discusses the need for nurse mentors to receive adequate support to ensure that their experience, and the students, is a positive one. The authors explore how the development of the advanced training practice (ATP) scheme in general prac... Read More about Implementing a mentor support system for general practice nurse mentors.

The displacement effect of convenience: The case of recycling (2017)
Journal Article
Abbott, A., Nandeibam, S., & O'Shea, L. (2017). The displacement effect of convenience: The case of recycling. Ecological economics : the journal of the International Society for Ecological Economics, 136, 159-168. https://doi.org/10.1016/j.ecolecon.2017.01.020

© 2017 Elsevier B.V. In light of increasingly ambitious recycling targets it is important to analyse the potential displacement effect of improving access to kerbside provision on other forms of recycling. Do households view the different modes of re... Read More about The displacement effect of convenience: The case of recycling.

Management challenges in creating value from business analytics (2017)
Journal Article
Vidgen, R., Shaw, S. L., & Grant, D. B. (2017). Management challenges in creating value from business analytics. European journal of operational research, 261(2), 626-639. https://doi.org/10.1016/j.ejor.2017.02.023

The popularity of big data and business analytics has increased tremendously in the last decade and a key challenge for organizations is in understanding how to leverage them to create business value. However, while the literature acknowledges the im... Read More about Management challenges in creating value from business analytics.

Mitochondrial DNA analysis of eneolithic trypillians from Ukraine reveals neolithic farming genetic roots (2017)
Journal Article
Nikitin, A. G., Potekhina, I., Lillie, M., Mallick, S., Nikitin, A., Potiekhina, I. D., …Rohland, N. (2017). Mitochondrial DNA analysis of eneolithic trypillians from Ukraine reveals neolithic farming genetic roots. PLoS ONE, 12(2), e0172952. https://doi.org/10.1371/journal.pone.0172952

The agricultural revolution in Eastern Europe began in the Eneolithic with the Cucuteni-Trypillia culture complex. In Ukraine, the Trypillian culture (TC) existed for over two millennia (ca. 5,400–2,700 BCE) and left a wealth of artifacts. Yet, their... Read More about Mitochondrial DNA analysis of eneolithic trypillians from Ukraine reveals neolithic farming genetic roots.