Mesenchymal stem cell-based Smad7 gene therapy for experimental liver cirrhosis
(2020)
Journal Article
Su, D., Wu, S., & Xu, S. (2020). Mesenchymal stem cell-based Smad7 gene therapy for experimental liver cirrhosis. Stem Cell Research and Therapy, 11(1), Article 395. https://doi.org/10.1186/s13287-020-01911-4
Background Bone mesenchymal stem cells (MSCs) can promote liver regeneration and inhibit inflammation and hepatic fibrosis. MSCs also can serve as a vehicle for gene therapy. Smad7 is an essential negative regulatory gene in the TGF-β1/Smad signalli... Read More about Mesenchymal stem cell-based Smad7 gene therapy for experimental liver cirrhosis.