All Outputs (2)

Investigating the efficacy of bisphosphonates treatment against multiple myeloma induced bone disease using a computational model (2014)
Journal Article
Ji, B., Yang, Q., Genever, P. G., & Fagan, M. J. (2014). Investigating the efficacy of bisphosphonates treatment against multiple myeloma induced bone disease using a computational model. Bio-medical materials and engineering, 24(6), 3373-3378. https://doi.org/10.3233/BME-141160

Multiple myeloma (MM)-induced bone disease is mortal for most MM patients. Bisphosphonates are first-line treatment for MM-induced bone disease, since it can inhibit osteoclast activity and the resultant bone resorption by suppressing the differentia... Read More about Investigating the efficacy of bisphosphonates treatment against multiple myeloma induced bone disease using a computational model.

Stereo visualization of 3D trabecular bone structures produced by bone remodelling simulation (2003)
Journal Article
Phillips, R., Grunchec, J. A., Ward, J. W., Fagan, M. J., Dobson, C. A., Langton, C. M., & Sisias, G. (2003). Stereo visualization of 3D trabecular bone structures produced by bone remodelling simulation. Studies in health technology and informatics, 94, 258-264. https://doi.org/10.3233/978-1-60750-938-7-258

Adult human bone is constantly being renewed by a process known as remodelling. For cancellous bone this renewal process occurs at the interface between bone and marrow where bone is depleted by osteoclasts and rebuilt by osteoblasts. This remodellin... Read More about Stereo visualization of 3D trabecular bone structures produced by bone remodelling simulation.