All Outputs (20)

Extracorporeal shockwave therapy compared with standard care for diabetic foot ulcer healing: An updated systematic review (2022)
Journal Article
Hitchman, L., Totty, J., Smith, G. E., Carradice, D., Twiddy, M., Iglesias, C., …Chetter, I. C. (2022). Extracorporeal shockwave therapy compared with standard care for diabetic foot ulcer healing: An updated systematic review. International wound journal, https://doi.org/10.1111/iwj.14035

Emerging evidence suggests that extracorporeal shockwave therapy (ESWT) may improve time to DFU healing. The aim of this review was to appraise the evidence on role of ESWT in DFU healing and impact of different ESWT doses. Databases were searched fo... Read More about Extracorporeal shockwave therapy compared with standard care for diabetic foot ulcer healing: An updated systematic review.

Wound complications following surgery to the lymph nodes: A protocol for a systematic review and meta-analysis (2022)
Journal Article
Nzenwa, I. C., Iqbal, H. A., Hardie, C., Smith, G. E., Matteucci, P. L., & Totty, J. P. (2022). Wound complications following surgery to the lymph nodes: A protocol for a systematic review and meta-analysis. PLoS ONE, 17(8), Article e0272490. https://doi.org/10.1371/journal.pone.0272490

Background Malignancies that spread to the lymph nodes may be identified through surgical biopsy, and treatment of metastatic disease may be through lymph node dissection. These surgeries, however, may be associated with significant adverse outcomes,... Read More about Wound complications following surgery to the lymph nodes: A protocol for a systematic review and meta-analysis.

Through-knee versus above-knee amputation for vascular and non-vascular major lower limb amputations (2021)
Journal Article
Crane, H., Boam, G., Carradice, D., Vanicek, N., Twiddy, M., & Smith, G. E. (2021). Through-knee versus above-knee amputation for vascular and non-vascular major lower limb amputations. The Cochrane database of systematic reviews, 2021(12), CD013839. https://doi.org/10.1002/14651858.CD013839.pub2

BACKGROUND: Diabetes and vascular disease are the leading causes of lower limb amputation. Currently, 463 million adults are living with diabetes, and 202 million with peripheral vascular disease, worldwide. When a lower limb amputation is considered... Read More about Through-knee versus above-knee amputation for vascular and non-vascular major lower limb amputations.

A rapid review and meta-regression analyses of the toxicological impacts of microplastic exposure in human cells. (2021)
Journal Article
Danopoulos, E., Twiddy, M., West, R., & Rotchell, J. M. (in press). A rapid review and meta-regression analyses of the toxicological impacts of microplastic exposure in human cells. Journal of hazardous materials, Article 127861. https://doi.org/10.1016/j.jhazmat.2021.127861

Humans are exposed to microplastics (MPs) daily via ingestion and inhalation. It is not known whether this results in adverse health effects and, if so, at what levels of exposure. Without epidemiological studies, human cell in vitro MP toxicological... Read More about A rapid review and meta-regression analyses of the toxicological impacts of microplastic exposure in human cells..

The role of diagnostic ultrasound imaging for patients with known prostate cancer within an active surveillance pathway: a systematic review (2021)
Journal Article
Simms, M., Parker, P., Rigby, A., Whybrow, P., & Twiddy, M. (in press). The role of diagnostic ultrasound imaging for patients with known prostate cancer within an active surveillance pathway: a systematic review. Ultrasound, https://doi.org/10.1177/1742271X21995212

Background: The use of multiparametric magnetic resonance imaging (mpMRI) within active surveillance of prostate cancer programmes is identified by the UK National Institute for Health and Care Excellence (NICE guideline NG 131 2019) as having a role... Read More about The role of diagnostic ultrasound imaging for patients with known prostate cancer within an active surveillance pathway: a systematic review.

Microplastic contamination of seafood intended for human consumption: a systematic review and meta-analysis (2020)
Journal Article
Danopoulos, E., Jenner, L., Twiddy, M., & Rotchell, J. M. (2020). Microplastic contamination of seafood intended for human consumption: a systematic review and meta-analysis. Environmental Health Perspectives, 128(12), 126002-1-126002-32. https://doi.org/10.1289/EHP7171

Background: Microplastics (MPs) have contaminated all compartments of the marine environment including biota such as seafood; ingestion from such sources is one of the two major uptake routes identified for human exposure. Objectives: The objectives... Read More about Microplastic contamination of seafood intended for human consumption: a systematic review and meta-analysis.

Microplastic contamination of salt intended for human consumption: a systematic review and meta-analysis (2020)
Journal Article
Danopoulos, E., Jenner, L., Twiddy, M., & Rotchell, J. M. (2020). Microplastic contamination of salt intended for human consumption: a systematic review and meta-analysis. SN Applied Sciences, 2(12), Article 1950. https://doi.org/10.1007/s42452-020-03749-0

Microplastics (MPs) are an emerging contaminant ubiquitous in the environment. There is growing concern regarding potential human health effects, a major human exposure route being dietary uptake. We have undertaken a systematic review (SR) and meta-... Read More about Microplastic contamination of salt intended for human consumption: a systematic review and meta-analysis.

Presurgery exercise-based conditioning interventions (prehabilitation) in adults undergoing lower limb surgery for peripheral arterial disease (Review) (2020)
Journal Article
Palmer, J., Pymer, S., Smith, G. E., Harwood, A., Ingle, L., Huang, C., & Chetter, I. C. (2020). Presurgery exercise-based conditioning interventions (prehabilitation) in adults undergoing lower limb surgery for peripheral arterial disease (Review). The Cochrane database of systematic reviews, 2020(9), Article CD013407. https://doi.org/10.1002/14651858.CD013407.pub2

Copyright © 2020 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd. Background: Lower limb peripheral arterial disease (PAD) is a type of cardiovascular disease where the blood vessels that carry the blood to the legs are hardened and... Read More about Presurgery exercise-based conditioning interventions (prehabilitation) in adults undergoing lower limb surgery for peripheral arterial disease (Review).

The relationship between maternal personality disorder and early birth outcomes: A systematic review and meta-analysis (2020)
Journal Article
Marshall, C., Jomeen, J., Huang, C., & Martin, C. (2020). The relationship between maternal personality disorder and early birth outcomes: A systematic review and meta-analysis. International Journal of Environmental Research and Public Health, 17(16), 1-19. https://doi.org/10.3390/ijerph17165778

Title: Systematic review and meta-analysis of the relationship between maternal personality disorder and early birth outcomes. Background: Women with personality disorder are at risk of social and emotional problems which impact deleteriously on eve... Read More about The relationship between maternal personality disorder and early birth outcomes: A systematic review and meta-analysis.

Microplastic contamination of drinking water: a systematic review. (2020)
Journal Article
Danopoulos, E., Twiddy, M., & Rotchell, J. M. (2020). Microplastic contamination of drinking water: a systematic review. PLoS ONE, 15(7 July), Article e0236838. https://doi.org/10.1371/journal.pone.0236838

Background Microplastics (MPs) are omnipresent in the environment, including the human food chain; a likely important contributor to human exposure is drinking water. Objective To undertake a systematic review of MP contamination of drinking water... Read More about Microplastic contamination of drinking water: a systematic review..

A systematic review of high-intensity interval training as an exercise intervention for intermittent claudication (2019)
Journal Article
Pymer, S., Palmer, J., Harwood, A. E., Ingle, L., Smith, G. E., & Chetter, I. C. (2019). A systematic review of high-intensity interval training as an exercise intervention for intermittent claudication. Journal of vascular surgery, https://doi.org/10.1016/j.jvs.2019.03.050

Background Intermittent claudication (IC) is the most common symptom of peripheral arterial disease, which significantly affects walking ability, functional capacity and quality of life. Supervised exercise programs (SEP) are recommended as first-lin... Read More about A systematic review of high-intensity interval training as an exercise intervention for intermittent claudication.

Patient and public involvement in health research in low and middle-income countries: a systematic review (2019)
Journal Article
Cook, N., Siddiqi, N., Twiddy, M., & Kenyon, R. (2019). Patient and public involvement in health research in low and middle-income countries: a systematic review. BMJ open, 9(5), Article e026514. https://doi.org/10.1136/bmjopen-2018-026514

Objectives: Patient and public involvement (PPI) is argued to lead to higher quality health research, which is more relatable to and helps empower the public. We synthesised the evidence to look for examples of PPI in health research in low/middle-in... Read More about Patient and public involvement in health research in low and middle-income countries: a systematic review.

Validity and effectiveness of paediatric early warning systems and track and trigger tools for identifying and reducing clinical deterioration in hospitalised children: a systematic review (2019)
Journal Article
Trubey, R., Huang, C., Lugg-Widger, F. V., Hood, K., Allen, D., Edwards, D., …Powell, C. (2019). Validity and effectiveness of paediatric early warning systems and track and trigger tools for identifying and reducing clinical deterioration in hospitalised children: a systematic review. BMJ open, 9(5), Article e022105. https://doi.org/10.1136/bmjopen-2018-022105

© 2019 Author(s) (or their employer(s)). Re-use permitted under CC BY. Published by BMJ. Objective To assess (1) how well validated existing paediatric track and trigger tools (PTTT) are for predicting adverse outcomes in hospitalised children, and (... Read More about Validity and effectiveness of paediatric early warning systems and track and trigger tools for identifying and reducing clinical deterioration in hospitalised children: a systematic review.

Is cough important in acute exacerbations of COPD? (2018)
Journal Article
Crooks, M. G., Brown, T., & Morice, A. H. (2018). Is cough important in acute exacerbations of COPD?. Respiratory Physiology and Neurobiology, 257, 30-35. https://doi.org/10.1016/j.resp.2018.02.005

Chronic obstructive pulmonary disease is predicted to become the 4th leading cause of death worldwide by 2030. The natural history of the disease includes progressive symptoms punctuated by acute exacerbations during which symptoms rapidly deteriorat... Read More about Is cough important in acute exacerbations of COPD?.

A systematic review of muscle morphology and function in intermittent claudication (2017)
Journal Article
Harwood, A. E., King, S., Totty, J., Smith, G. E., Vanicek, N., & Chetter, I. C. (2017). A systematic review of muscle morphology and function in intermittent claudication. Journal of vascular surgery, 66(4), 1241-1257. https://doi.org/10.1016/j.jvs.2017.05.106

Objective Intermittent claudication (IC) is frequently associated with deterioration in walking capacity and physical function, and it can often result in an impairment in balance. Whereas supervised exercise is recommended by the National Institute... Read More about A systematic review of muscle morphology and function in intermittent claudication.

The patients’ experience of a bladder cancer diagnosis: a systematic review of the qualitative evidence (2017)
Journal Article
Edmondson, A. J., Birtwistle, J. C., Catto, J. W., & Twiddy, M. (2017). The patients’ experience of a bladder cancer diagnosis: a systematic review of the qualitative evidence. Journal of cancer survivorship : research and practice, 11(4), 453-461. https://doi.org/10.1007/s11764-017-0603-6

© 2017, The Author(s). Purpose: Bladder cancer (BC) is a common disease with disparate treatment options and variable outcomes. Despite the disease’s high prevalence, little is known of the lived experience of affected patients. National patient expe... Read More about The patients’ experience of a bladder cancer diagnosis: a systematic review of the qualitative evidence.

Patient-reported outcome measures for allergy and asthma in children (2016)
Journal Article
Soyiri, I. N., Nwaru, B. I., & Sheikh, A. (2016). Patient-reported outcome measures for allergy and asthma in children. Pediatric Allergy and Immunology, 27(8), 779-783. https://doi.org/10.1111/pai.12603

There is increasing recognition of the importance of patient's perceptions of disease and their assessments of heathcare processes. Patient‐reported outcome measures (PROMs) are therefore now regarded as at least as important as the traditional objec... Read More about Patient-reported outcome measures for allergy and asthma in children.

Systematic review of compression following treatment for varicose veins (2015)
Journal Article
El-Sheikha, J., Carradice, D., Nandhra, S., Leung, C., Smith, G., Campbell, B., & Chetter, I. (2015). Systematic review of compression following treatment for varicose veins. British journal of surgery, 102(7), 719-725. https://doi.org/10.1002/bjs.9788

Background Consensus regarding compression following treatment of varicose veins has yet to be reached. This systematic review aims to establish the optimal compression regimen after venous treatment. Methods A systematic review of MEDLINE, Embase an... Read More about Systematic review of compression following treatment for varicose veins.

Understanding causal associations between self-rated health and personal relationships in older adults: a review of evidence from longitudinal studies (2014)
Journal Article
Craigs, C. L., Twiddy, M., Parker, S. G., & West, R. M. (2014). Understanding causal associations between self-rated health and personal relationships in older adults: a review of evidence from longitudinal studies. Archives of Gerontology and Geriatrics, 59(2), 211-226. https://doi.org/10.1016/j.archger.2014.06.009

Abstract Background As we age we experience many life changes in our health, personal relationships, work, or home life which can impact on other aspects of our life. There is compelling evidence that how we feel about our health influences, or is i... Read More about Understanding causal associations between self-rated health and personal relationships in older adults: a review of evidence from longitudinal studies.

Evolving forecasting classifications and applications in health forecasting (2012)
Journal Article
Soyiri, I. N., & Reidpath, D. D. (2012). Evolving forecasting classifications and applications in health forecasting. International Journal of General Medicine, 5, 381-389. https://doi.org/10.2147/IJGM.S31079

Health forecasting forewarns the health community about future health situations and disease episodes so that health systems can better allocate resources and manage demand. The tools used for developing and measuring the accuracy and validity of hea... Read More about Evolving forecasting classifications and applications in health forecasting.