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Linking energy sensing to suppression of JAK-STAT signalling: A potential route for repurposing AMPK activators? (2017)
Journal Article
Speirs, C., Williams, J. J. L., Riches, K., Salt, I. P., & Palmer, T. M. (2018). Linking energy sensing to suppression of JAK-STAT signalling: A potential route for repurposing AMPK activators?. Pharmacological research : the official journal of the Italian Pharmacological Society, 128, 88-100. https://doi.org/10.1016/j.phrs.2017.10.001

Exaggerated Janus kinase-signal transducer and activator of transcription (JAK-STAT) signalling is key to the pathogenesis of pro-inflammatory disorders, such as rheumatoid arthritis and cardiovascular diseases. Mutational activation of JAKs is also... Read More about Linking energy sensing to suppression of JAK-STAT signalling: A potential route for repurposing AMPK activators?.

Dying comfortably in very old age with or without dementia in different care settings - A representative "older old" population study (2017)
Journal Article
Fleming, J., Calloway, R., Perrels, A., Farquhar, M., Barclay, S., Brayne, C., …Zhao, E. (2017). Dying comfortably in very old age with or without dementia in different care settings - A representative "older old" population study. BMC Geriatrics, 17(1), https://doi.org/10.1186/s12877-017-0605-2

Background: Comfort is frequently ranked important for a good death. Although rising numbers of people are dying in very old age, many with dementia, little is known about symptom control for "older old" people or whether care in different settings e... Read More about Dying comfortably in very old age with or without dementia in different care settings - A representative "older old" population study.

Pharmacology of cough in palliative care (2017)
Journal Article
Morice, A. H., & Shanks, G. (2017). Pharmacology of cough in palliative care. Current opinion in supportive and palliative care, 11(3), 147-151. https://doi.org/10.1097/SPC.0000000000000279

© 2017 Wolters Kluwer Health, Inc. All rights reserved. Purpose of review Cough is a common and distressing symptom. It has a marked decrement on quality-of-life particularly in the arena of palliative care where coexisting symptoms such as pain may... Read More about Pharmacology of cough in palliative care.

Area-level socioeconomic disadvantage and suicidal behaviour in Europe: A systematic review (2017)
Journal Article
Cairns, J. M., Graham, E., & Bambra, C. (2017). Area-level socioeconomic disadvantage and suicidal behaviour in Europe: A systematic review. Social science & medicine, 192, 102-111. https://doi.org/10.1016/j.socscimed.2017.09.034

© 2017 The relationship between adverse individual socio-economic circumstances and suicidal behaviour is well established. However, the impact of adverse collective circumstances – such as the socio-economic context where people live - is less well... Read More about Area-level socioeconomic disadvantage and suicidal behaviour in Europe: A systematic review.

A systematic review of muscle morphology and function in intermittent claudication (2017)
Journal Article
Harwood, A. E., King, S., Totty, J., Smith, G. E., Vanicek, N., & Chetter, I. C. (2017). A systematic review of muscle morphology and function in intermittent claudication. Journal of vascular surgery, 66(4), 1241-1257. https://doi.org/10.1016/j.jvs.2017.05.106

Objective Intermittent claudication (IC) is frequently associated with deterioration in walking capacity and physical function, and it can often result in an impairment in balance. Whereas supervised exercise is recommended by the National Institute... Read More about A systematic review of muscle morphology and function in intermittent claudication.

Exploring the training potential of recent virtual robotic platforms: A comprehensive review (2017)
Journal Article
Ali Ajwad, S., Ul islam, R., & Iqbal, J. (2017). Exploring the training potential of recent virtual robotic platforms: A comprehensive review. Journal of Advancements in Robotics, 4(2), 9-25

In recent years, deployment of robotic manipulators in industries and other fields has increased significantly. This growing trend highlights the need of trained engineers and technicians. Virtual robotic platforms facilitate engineers to acquire kno... Read More about Exploring the training potential of recent virtual robotic platforms: A comprehensive review.

Signs and symptoms preceding the diagnosis of Alzheimer's disease: A systematic scoping review of literature from 1937 to 2016 (2017)
Journal Article
Bature, F., Guinn, B. A., Pang, D., & Pappas, Y. (2017). Signs and symptoms preceding the diagnosis of Alzheimer's disease: A systematic scoping review of literature from 1937 to 2016. BMJ open, 7(8), Article e015746. https://doi.org/10.1136/bmjopen-2016-015746

OBJECTIVE: Late diagnosis of Alzheimer's disease (AD) may be due to diagnostic uncertainties. We aimed to determine the sequence and timing of the appearance of established early signs and symptoms in people who are subsequently diagnosed with AD.... Read More about Signs and symptoms preceding the diagnosis of Alzheimer's disease: A systematic scoping review of literature from 1937 to 2016.

Heart failure - what's new and what's changed? (2017)
Journal Article
Callan, P. D., & Clark, A. L. (2017). Heart failure - what's new and what's changed?. Clinical Medicine, 16(Suppl_6), s37-s42. https://doi.org/10.7861/clinmedicine.16-6-s37

Physicians responsible for the care of patients with heart failure due to left ventricular systolic dysfunction have access to a broad range of evidence-based treatments that prolong life and reduce symptoms. In spite of the significant progress made... Read More about Heart failure - what's new and what's changed?.

In-hospital worsening heart failure: a clinically relevant endpoint? (2017)
Journal Article
Clark, A. L., Cherif, M., McDonagh, T. A., & Squire, I. B. (2018). In-hospital worsening heart failure: a clinically relevant endpoint?. ESC Heart Failure, 5(1), 9-18. https://doi.org/10.1002/ehf2.12195

Outcome measures used for the clinical evaluation of patients with acute heart failure differ between studies and may neither adequately address the characteristic presenting symptoms and signs nor reflect the pathophysiological processes involved. I... Read More about In-hospital worsening heart failure: a clinically relevant endpoint?.

The emerging role of the eosinophil and its measurement in chronic cough (2017)
Journal Article
Sadeghi, M. H., & Morice, A. H. (2017). The emerging role of the eosinophil and its measurement in chronic cough. Open Respiratory Medicine Journal, 11, 17-30. https://doi.org/10.2174/1874306401711010017

© 2017 Sadeghi & Morice. Although the aetiology of chronic cough in guidelines is clearly stated as asthma and related syndromes, gastrooesophageal reflux disease (GORD), and upper airways disease, the inflammatory mechanisms underlying these condi... Read More about The emerging role of the eosinophil and its measurement in chronic cough.

The changing prevalence and incidence of dementia over time-current evidence (2017)
Journal Article
Wu, Y. T., Beiser, A. S., Breteler, M. M., Fratiglioni, L., Helmer, C., Hendrie, H. C., …Brayne, C. (2017). The changing prevalence and incidence of dementia over time-current evidence. Nature Reviews Neurology, 13(6), 327-339. https://doi.org/10.1038/nrneurol.2017.63

Dementia is an increasing focus for policymakers, civil organizations and multidisciplinary researchers. The most recent descriptive epidemiological research into dementia is enabling investigation into how the prevalence and incidence are changing o... Read More about The changing prevalence and incidence of dementia over time-current evidence.

Drosophila Short stop as a paradigm for the role and regulation of spectraplakins (2017)
Journal Article
Voelzmann, A., Liew, Y. T., Qu, Y., Hahn, I., Melero, C., Sánchez-Soriano, N., & Prokop, A. (2017). Drosophila Short stop as a paradigm for the role and regulation of spectraplakins. Seminars in Cell & Developmental Biology, 69, 40-57. https://doi.org/10.1016/j.semcdb.2017.05.019

Spectraplakins are evolutionarily well conserved cytoskeletal linker molecules that are true members of three protein families: plakins, spectrins and Gas2-like proteins. Spectraplakin genes encode at least 7 characteristic functional domains which a... Read More about Drosophila Short stop as a paradigm for the role and regulation of spectraplakins.

Quality of missing data reporting and handling in palliative care trials demonstrates that further development of the CONSORT statement is required : a systematic review (2017)
Journal Article
Hussain, J. A., Johnson, M. J., Currow, D. C., White, I. R., Currow, D., Hussain, J., …White, I. (2017). Quality of missing data reporting and handling in palliative care trials demonstrates that further development of the CONSORT statement is required : a systematic review. Journal of clinical epidemiology, 88, 81-91. https://doi.org/10.1016/j.jclinepi.2017.05.009

Objectives Assess (i) the quality of reporting and handling of missing data (MD) in palliative care trials, (ii) whether there are differences in the reporting of criteria specified by the Consolidated Standards of Reporting Trials (CONSORT) 2010 sta... Read More about Quality of missing data reporting and handling in palliative care trials demonstrates that further development of the CONSORT statement is required : a systematic review.

Literature review on the ‘Smart Factory’ concept using bibliometric tools (2017)
Journal Article
Strozzi, F., Colicchia, C., Creazza, A., & Noè, C. (2017). Literature review on the ‘Smart Factory’ concept using bibliometric tools. International Journal of Production Research, 55(22), 6572-6591. https://doi.org/10.1080/00207543.2017.1326643

The objective of this paper is to depict a landscape of the scientific literature on the concept of the ‘Smart Factory’, which in recent years is gaining more and more attention from academics and practitioners because of significant innovations in t... Read More about Literature review on the ‘Smart Factory’ concept using bibliometric tools.

Cough hypersensitivity syndrome: A few more steps forward (2017)
Journal Article
Song, W. J., & Morice, A. H. (2017). Cough hypersensitivity syndrome: A few more steps forward. Allergy Asthma and Immunology Research, 9(5), 394-402. https://doi.org/10.4168/aair.2017.9.5.394

© The Korean Academy of Asthma, Allergy and Clinical Immunology. Cough reflex is a vital protective mechanism against aspiration, but when dysregulated, it can become hypersensitive. In fact, chronic cough is a significant medical problem with a high... Read More about Cough hypersensitivity syndrome: A few more steps forward.

Which interval is most crucial to presentation and survival in gastroesophageal cancer: a systematic review (2017)
Journal Article
Lee, A., Khulusi, S., & Watson, R. (2017). Which interval is most crucial to presentation and survival in gastroesophageal cancer: a systematic review. Journal of advanced nursing, 73(10), 2270-2282. https://doi.org/10.1111/jan.13308

Aim: The aim of this study was to identify the most crucial interval to encourage earlier diagnosis in with gastroesophageal cancer and to identify potential factors effecting this interval. Background: Gastroesophageal malignancy is the eighth most... Read More about Which interval is most crucial to presentation and survival in gastroesophageal cancer: a systematic review.

The environmental and evolutionary history of Lake Ohrid (FYROM/Albania): Interim results from the SCOPSCO deep drilling project (2017)
Journal Article
Wagner, B., Wilke, T., Francke, A., Albrecht, C., Baumgarten, H., Bertini, A., …Zhang, X. S. (2017). The environmental and evolutionary history of Lake Ohrid (FYROM/Albania): Interim results from the SCOPSCO deep drilling project. Biogeosciences, 14(8), 2033-2054. https://doi.org/10.5194/bg-14-2033-2017

This study reviews and synthesises existing information generated within the SCOPSCO (Scientific Collaboration on Past Speciation Conditions in Lake Ohrid) deep drilling project. The four main aims of the project are to infer (i) the age and origin o... Read More about The environmental and evolutionary history of Lake Ohrid (FYROM/Albania): Interim results from the SCOPSCO deep drilling project.

Microplastics in the Antarctic marine system: An emerging area of research (2017)
Journal Article
Waller, C. L., Griffiths, H. J., Waluda, C. M., Thorpe, S. E., Loaiza, I., Moreno, B., …Hughes, K. A. (2017). Microplastics in the Antarctic marine system: An emerging area of research. The Science of the total environment, 598, 220-227. https://doi.org/10.1016/j.scitotenv.2017.03.283

It was thought that the Southern Ocean was relatively free of microplastic contamination; however, recent studies and citizen science projects in the Southern Ocean have reported microplastics in deep-sea sediments and surface waters. Here we reviewe... Read More about Microplastics in the Antarctic marine system: An emerging area of research.