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All Outputs (2)

Development of synthetic routes towards bis (macrocyclic) compounds for imaging and therapy of cancer (2008)
Thesis
Welch, C. J. Development of synthetic routes towards bis (macrocyclic) compounds for imaging and therapy of cancer. (Thesis). University of Hull. https://hull-repository.worktribe.com/output/4208906

Porphyrin molecules are efficient generators of singlet oxygen and are used as photosensitisers in PDT. They are also known to accumulate in tumour tissue due to the hyperpermeability of tumour vasculature and poor lymphatic drainage, thus exhibiting... Read More about Development of synthetic routes towards bis (macrocyclic) compounds for imaging and therapy of cancer.

The preparation of lanthanide macrocyclic complexes for use as MRI and luminescence contrast agents (2008)
Thesis
Sparke, A. E. The preparation of lanthanide macrocyclic complexes for use as MRI and luminescence contrast agents. (Thesis). University of Hull. https://hull-repository.worktribe.com/output/4212783

Multimodality imaging agents have the potential to be detected in both MRI and optical imaging experiments allowing for visualisation of biological systems from the cellular level up to the whole body. Lanthanide complexes have shown great promise as... Read More about The preparation of lanthanide macrocyclic complexes for use as MRI and luminescence contrast agents.