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Clinical characteristics and impact of inducible laryngeal obstruction in the UK national registry (2024)
Journal Article
Haines, J., Simpson, A., Slinger, C., Selby, J., Pargeter, N., Fowler, S., & Hull, J. (in press). Clinical characteristics and impact of inducible laryngeal obstruction in the UK national registry. The journal of allergy and clinical immunology. In practice, https://doi.org/10.1016/j.jaip.2024.01.030

Background Inducible laryngeal obstruction (ILO) describes inappropriate laryngeal closure during respiration, with airflow obstruction occurring at the glottic and/or supraglottic level, leading to breathlessness. Objective There is a paucity of... Read More about Clinical characteristics and impact of inducible laryngeal obstruction in the UK national registry.

Airflow rates and breathlessness recovery from submaximal exercise in healthy adults: prospective, randomised, cross-over study (2023)
Journal Article
Brew, A., O'Beirne, S., Johnson, M. J., Ramsenthaler, C., Watson, P., Rubini, P. A., …Simpson, A. (in press). Airflow rates and breathlessness recovery from submaximal exercise in healthy adults: prospective, randomised, cross-over study. BMJ supportive & palliative care, https://doi.org/10.1136/spcare-2023-004309

Objectives: Facial airflow from a hand-held fan may reduce breathlessness severity and hasten postexertion recovery. Data from randomised controlled trials are limited and the optimal airflow speed remains unknown. We aimed to determine the effect of... Read More about Airflow rates and breathlessness recovery from submaximal exercise in healthy adults: prospective, randomised, cross-over study.

Student expectations of teaching and learning when starting university: a systematic review (2023)
Journal Article
Tomlinson, A., Simpson, A., & Killingback, C. (2023). Student expectations of teaching and learning when starting university: a systematic review. Journal of Further and Higher Education, https://doi.org/10.1080/0309877X.2023.2212242

Student expectations are complex constructs that can influence adaptability, engagement, achievement, satisfaction and retention. A number of individual studies have been published on the expectations of students when starting university, however non... Read More about Student expectations of teaching and learning when starting university: a systematic review.

Exercise and asthma – trigger or treatment? (2023)
Journal Article
Simpson, A. J., & Price, O. J. (2023). Exercise and asthma – trigger or treatment?. Respiratory medicine, 213, Article 107247. https://doi.org/10.1016/j.rmed.2023.107247

Exercise is one of the most commonly reported symptom triggers for people with asthma. However, a growing body of evidence indicates that regular exercise and physical activity are associated with improved clinical and patient reported outcomes. In t... Read More about Exercise and asthma – trigger or treatment?.

Fractional exhaled nitric oxide in the assessment of exercise-induced bronchoconstriction: A multicenter retrospective analysis of UK-based athletes (2023)
Journal Article
Dickinson, J., Gowers, W., Sturridge, S., Williams, N., Kippelen, P., Simpson, A., …Price, O. J. (2023). Fractional exhaled nitric oxide in the assessment of exercise-induced bronchoconstriction: A multicenter retrospective analysis of UK-based athletes. Scandinavian Journal of Medicine and Science in Sports, https://doi.org/10.1111/sms.14367

Introduction: Exercise-induced bronchoconstriction (EIB) is not only highly prevalent in people with asthma, but can also occur independently, particularly in athletes. Fractional exhaled nitric oxide (FeNO) is an indirect biomarker of type 2 airway... Read More about Fractional exhaled nitric oxide in the assessment of exercise-induced bronchoconstriction: A multicenter retrospective analysis of UK-based athletes.

Short-term heat acclimation protocols for an aging population: Systematic review (2023)
Journal Article
Cole, E., Donnan, K. J., Simpson, A. J., & Garrett, A. T. (2023). Short-term heat acclimation protocols for an aging population: Systematic review. PLoS ONE, 18(3 March), Article e0282038. https://doi.org/10.1371/journal.pone.0282038

Introduction Elderly and sedentary individuals are particularly vulnerable to heat related illness. Short-term heat acclimation (STHA) can decrease both the physical and mental stress imposed on individuals performing tasks in the heat. However, the... Read More about Short-term heat acclimation protocols for an aging population: Systematic review.

Domiciliary fractional exhaled nitric oxide and spirometry in monitoring asthma control and exacerbations (2023)
Journal Article
Wang, R., Usmani, O. S., Chung, K. F., Sont, J., Simpson, A., Bonini, M., …Fowler, S. J. (2023). Domiciliary fractional exhaled nitric oxide and spirometry in monitoring asthma control and exacerbations. The journal of allergy and clinical immunology. In practice, 11(6), 1787-1795.e5. https://doi.org/10.1016/j.jaip.2023.02.009

Background: Domiciliary measurements of airflow obstruction and inflammation may assist healthcare teams and patients in determining asthma control and facilitate self-management. Objective: To evaluate parameters derived from domiciliary spirometry... Read More about Domiciliary fractional exhaled nitric oxide and spirometry in monitoring asthma control and exacerbations.

Telerehabilitation for patients who have been hospitalised with covid-19: a qualitative study (2023)
Journal Article
Killingback, C., Thompson, M., Nettleton, M., Hyde, L., Marshall, P., Shepherdson, J., …Simpson, A. J. (2023). Telerehabilitation for patients who have been hospitalised with covid-19: a qualitative study. Disability and Rehabilitation, https://doi.org/10.1080/09638288.2022.2159075

Purpose: The aim of this qualitative study was to explore the views of participants of a group-based, supervised, telerehabilitation programme, following discharge from hospital with Covid-19. This study was part of a single-centre, fast-track (wait-... Read More about Telerehabilitation for patients who have been hospitalised with covid-19: a qualitative study.

Group-based pulmonary telerehabilitation is feasible, safe, beneficial and well-received in patients who have been hospitalised with COVID-19 (2022)
Journal Article
Simpson, A. J., Green, A., Nettleton, M., Hyde, L., Shepherdson, J., Killingback, C., …Crooks, M. G. (2023). Group-based pulmonary telerehabilitation is feasible, safe, beneficial and well-received in patients who have been hospitalised with COVID-19. ERJ Open Research, 9(2), Article 00373-2022. https://doi.org/10.1183/23120541.00373-2022

Introduction Coronavirus disease 2019 (COVID-19) has caused worldwide mass hospitalisation. The need for multidisciplinary post-hospitalisation rehabilitation is becoming increasingly apparent, and telerehabilitation has been endorsed. The aim of stu... Read More about Group-based pulmonary telerehabilitation is feasible, safe, beneficial and well-received in patients who have been hospitalised with COVID-19.

Effectiveness of short-term isothermic-heat acclimation (4 days) on physical performance in moderately trained males (2022)
Journal Article
Shaw, J., Walkington, C., Cole, E., Gleadall-Siddall, D. O., Burke, R., Bray, J., …Garrett, A. T. (2022). Effectiveness of short-term isothermic-heat acclimation (4 days) on physical performance in moderately trained males. PLoS ONE, 17(11), Article e0270093. https://doi.org/10.1371/journal.pone.0270093

Introduction A typical heat acclimation (HA) protocol takes 5–7 d of 60–90 minutes of heat exposure. Identifying the minimum dose of HA required to elicit a heat adapted phenotype could reduce financial constraints on participants and aid in the tape... Read More about Effectiveness of short-term isothermic-heat acclimation (4 days) on physical performance in moderately trained males.

A comparison of the knowledge and attitudes of concussion within higher and lower leagues of the community rugby union game (2022)
Journal Article
Oliver, B., Ashton, J., Welsby, G., & Simpson, A. (2022). A comparison of the knowledge and attitudes of concussion within higher and lower leagues of the community rugby union game. Physical Therapy in Sport, 58, 151-159. https://doi.org/10.1016/j.ptsp.2022.10.009

Objectives: The Rugby Football Union (RFU) HEADCASE initiative aims to educate coaches, referees, and players on concussion. Concussion in community rugby is under-reported. Therefore, players can play a role in concussion safety if they have adequat... Read More about A comparison of the knowledge and attitudes of concussion within higher and lower leagues of the community rugby union game.

Errors of measurement for blood parameters, physiological and performance measures after the decay of short-term heat acclimation (2022)
Journal Article
Garrett, A. T., Rehrer, N. J., Patterson, M. J., Simpson, A. J., & Cotter, J. D. (2022). Errors of measurement for blood parameters, physiological and performance measures after the decay of short-term heat acclimation. Journal of Human Performance in Extreme Environments, 17(1), Article 5. https://doi.org/10.7771/2327-2937.1140

Introduction: It is important to determine the accuracy of measurements relative to potential treatment effects, with time intervals between tests. Purpose: The aim of this study was to assess the error of measurement for blood parameters, physiologi... Read More about Errors of measurement for blood parameters, physiological and performance measures after the decay of short-term heat acclimation.

Tele-rehabilitation for patients who have been hospitalised with Covid-19: a mixed-methods feasibility trial protocol (2022)
Journal Article
Hyde, L., Simpson, A. J., Nettleton, M., Shepherdson, J., Killingback, C., Marshall, P., …Green, A. (2022). Tele-rehabilitation for patients who have been hospitalised with Covid-19: a mixed-methods feasibility trial protocol. Physical Therapy Reviews, https://doi.org/10.1080/10833196.2022.2028963

Background: Tele-rehabilitation has been proposed as a post-hospitalisation rehabilitation pathway for Covid-19 survivors, however patients’ willingness and ability to engage with this online intervention remains unknown. Objectives: The aim of this... Read More about Tele-rehabilitation for patients who have been hospitalised with Covid-19: a mixed-methods feasibility trial protocol.

Medication adherence in patients with severe asthma prescribed oral corticosteroids in the U-BIOPRED cohort (2021)
Journal Article
Ahmed, H., Auffray, C., Bakke, P., Bush, A., Baribaud, F., Bates, S., …Study Group, U. (2021). Medication adherence in patients with severe asthma prescribed oral corticosteroids in the U-BIOPRED cohort. Chest, 160(1), 53-64. https://doi.org/10.1016/j.chest.2021.02.023

Background: Although estimates of suboptimal adherence to oral corticosteroids in asthma range from 30% to 50%, no ideal method for measurement exists; the impact of poor adherence in severe asthma is likely to be particularly high. Research Question... Read More about Medication adherence in patients with severe asthma prescribed oral corticosteroids in the U-BIOPRED cohort.

Triggers of Breathlessness in Inducible Laryngeal Obstruction and Asthma (2020)
Journal Article
Haines, J., Chua, S. H., Smith, J., Slinger, C., Simpson, A. J., & Fowler, S. J. (2020). Triggers of Breathlessness in Inducible Laryngeal Obstruction and Asthma. Clinical and Experimental Allergy, 50(11), 1230-1237. https://doi.org/10.1111/cea.13715

Background Inducible laryngeal obstruction (ILO) is often misdiagnosed as, or may coexist with, asthma. Identifying differences in triggering factors may assist clinicians to differentiate between the two conditions, and could give mechanistic insig... Read More about Triggers of Breathlessness in Inducible Laryngeal Obstruction and Asthma.

Effectiveness of myAirCoach: A mHealth Self-Management System in Asthma (2020)
Journal Article
Khusial, R. J., Honkoop, P. J., Usmani, O., Soares, M., Simpson, A., Biddiscombe, M., …Sont, J. K. (2020). Effectiveness of myAirCoach: A mHealth Self-Management System in Asthma. The journal of allergy and clinical immunology. In practice, 8(6), 1972-1979.e8. https://doi.org/10.1016/j.jaip.2020.02.018

Background: Self-management programs have beneficial effects on asthma control, but their implementation in clinical practice is poor. Mobile health (mHealth) could play an important role in enhancing self-management. Objective: To assess the clinica... Read More about Effectiveness of myAirCoach: A mHealth Self-Management System in Asthma.

Effect of creatine supplementation on the airways of youth elite soccer players (2019)
Journal Article
Simpson, A. J., Horne, S., Sharp, P., Sharps, R., & Kippelen, P. (2019). Effect of creatine supplementation on the airways of youth elite soccer players. Medicine and Science in Sports and Exercise, 51(8), 1582-1590. https://doi.org/10.1249/MSS.0000000000001979

Introduction Owing to its well-established ergogenic potential, creatine is a highly popular food supplement in sports. As an oral supplement, creatine is considered safe and ethical. However, no data exist on the safety of creatine on lung function... Read More about Effect of creatine supplementation on the airways of youth elite soccer players.