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All Outputs (15)

Evaluating the Role of Ultrasound in Prostate cancer (ERUP) trial – Phase 1 early experience of micro-ultrasound in the UK (2024)
Journal Article
Parker, P., Twiddy, M., Rigby, A., Whybrow, P., & Simms, M. (2024). Evaluating the Role of Ultrasound in Prostate cancer (ERUP) trial – Phase 1 early experience of micro-ultrasound in the UK. Ultrasound, https://doi.org/10.1177/1742271X231226302

Purpose: To evaluate if the use of micro-ultrasound (microUS) can detect significant prostate (csPCa) pathology when compared to histology obtained during a transperineal prostate biopsy. Methods: Patients suspected of having prostate cancer, who h... Read More about Evaluating the Role of Ultrasound in Prostate cancer (ERUP) trial – Phase 1 early experience of micro-ultrasound in the UK.

Examining the knowledge work of person-centred care: Towards epistemic reciprocity (2022)
Journal Article
Dell'Olio, M., Whybrow, P., & Reeve, J. (2023). Examining the knowledge work of person-centred care: Towards epistemic reciprocity. Patient Education and Counseling, 107, Article 107575. https://doi.org/10.1016/j.pec.2022.107575

Objective: It is increasingly recognised that when healthcare staff fails to give adequate credence to patients' illness-related knowledge work, this epistemic injustice undermines person-centred care. Therefore, we set out to examine the experiences... Read More about Examining the knowledge work of person-centred care: Towards epistemic reciprocity.

Endoscopic urethrotomy versus open urethroplasty for men with bulbar urethral stricture: the OPEN randomised trial cost-effectiveness analysis (2021)
Journal Article
Shen, J., Vale, L., Goulao, B., Whybrow, P., Payne, S., Watkin, N., & OPEN trial investigators. (2021). Endoscopic urethrotomy versus open urethroplasty for men with bulbar urethral stricture: the OPEN randomised trial cost-effectiveness analysis. BMC Urology, 21(1), Article 76. https://doi.org/10.1186/s12894-021-00836-1

Abstract Background: Bulbar urethral stricture is a common cause for urinary symptoms in men and its two main treatment options both have drawbacks with little evidence on their relative cost-efectiveness. Current guidelines on the management of re... Read More about Endoscopic urethrotomy versus open urethroplasty for men with bulbar urethral stricture: the OPEN randomised trial cost-effectiveness analysis.

The role of diagnostic ultrasound imaging for patients with known prostate cancer within an active surveillance pathway: a systematic review (2021)
Journal Article
Simms, M., Parker, P., Rigby, A., Whybrow, P., & Twiddy, M. (in press). The role of diagnostic ultrasound imaging for patients with known prostate cancer within an active surveillance pathway: a systematic review. Ultrasound, https://doi.org/10.1177/1742271X21995212

Background: The use of multiparametric magnetic resonance imaging (mpMRI) within active surveillance of prostate cancer programmes is identified by the UK National Institute for Health and Care Excellence (NICE guideline NG 131 2019) as having a role... Read More about The role of diagnostic ultrasound imaging for patients with known prostate cancer within an active surveillance pathway: a systematic review.

‘It's just one of those natural progressions': Stories of relocating to neighbourhoods of high and low walkability (2021)
Journal Article
Whybrow, P., Bramley, G., & Brown, C. (2021). ‘It's just one of those natural progressions': Stories of relocating to neighbourhoods of high and low walkability. Health and Place, 69, Article 102509. https://doi.org/10.1016/j.healthplace.2021.102509

Walkable neighbourhood characteristics, such as connectivity and land use mix, have been found to correlate with people walking more and being active. However, the relationship between the built environment and behaviour is highly complex making it d... Read More about ‘It's just one of those natural progressions': Stories of relocating to neighbourhoods of high and low walkability.

Professional identity formation within longitudinal integrated clerkships: A scoping review (2021)
Journal Article
Brown, M. E. L., Whybrow, P., Kirwan, G., & Finn, G. M. (in press). Professional identity formation within longitudinal integrated clerkships: A scoping review. Medical Education, https://doi.org/10.1111/medu.14461

Context Although the uptake of Longitudinal Integrated Clerkships (LICs) is increasing worldwide, and there are documented benefits to participation, there is a lack of conceptual evidence regarding how LICs exert many of their benefits, including t... Read More about Professional identity formation within longitudinal integrated clerkships: A scoping review.

Open urethroplasty versus endoscopic urethrotomy for recurrent urethral stricture in men: the OPEN RCT (2020)
Journal Article
Pickard, R., Goulao, B., Carnell, S., Shen, J., MacLennan, G., Norrie, J., …Watkin, N. (in press). Open urethroplasty versus endoscopic urethrotomy for recurrent urethral stricture in men: the OPEN RCT. Health Technology Assessment, 24(61), 1-110. https://doi.org/10.3310/hta24610

Background: Men who suffer recurrence of bulbar urethral stricture have to decide between endoscopic urethrotomy and open urethroplasty to manage their urinary symptoms. Evidence of relative clinical effectiveness and cost-effectiveness is lacking.... Read More about Open urethroplasty versus endoscopic urethrotomy for recurrent urethral stricture in men: the OPEN RCT.

Surgical Treatment for Recurrent Bulbar Urethral Stricture: A Randomised Open-label Superiority Trial of Open Urethroplasty Versus Endoscopic Urethrotomy (the OPEN Trial) (2020)
Journal Article
Goulao, B., Carnell, S., Shen, J., MacLennan, G., Norrie, J., Cook, J., …Pickard, R. (2020). Surgical Treatment for Recurrent Bulbar Urethral Stricture: A Randomised Open-label Superiority Trial of Open Urethroplasty Versus Endoscopic Urethrotomy (the OPEN Trial). European Urology, 78(4), 572-580. https://doi.org/10.1016/j.eururo.2020.06.003

Background Urethral stricture affects 0.9% of men. Initial treatment is urethrotomy. Approximately, half of the strictures recur within 4 yr. Options for further treatment are repeat urethrotomy or open urethroplasty. Objective To compare the effe... Read More about Surgical Treatment for Recurrent Bulbar Urethral Stricture: A Randomised Open-label Superiority Trial of Open Urethroplasty Versus Endoscopic Urethrotomy (the OPEN Trial).

Physiotherapy outcome measures of haemophilia acute bleed episodes: What matters to patients? (2019)
Journal Article
Bradshaw, E., McClellan, C., Whybrow, P., & Cramp, F. (2019). Physiotherapy outcome measures of haemophilia acute bleed episodes: What matters to patients?. Haemophilia, 25(6), 1066-1072. https://doi.org/10.1111/hae.13840

Introduction The research was conducted at a UK teaching hospital and Haemophilia Comprehensive Care Centre (CCC) as part of a research programme investigating physiotherapy for acute bleed management. Aim The aim of the study was to understand th... Read More about Physiotherapy outcome measures of haemophilia acute bleed episodes: What matters to patients?.

Overcoming difficulties with equipoise to enable recruitment to a randomised controlled trial of partial ablation vs radical prostatectomy for unilateral localised prostate cancer (2018)
Journal Article
Elliott, D., Hamdy, F. C., Leslie, T. A., Rosario, D., Dudderidge, T., Hindley, R., …Donovan, J. L. (2018). Overcoming difficulties with equipoise to enable recruitment to a randomised controlled trial of partial ablation vs radical prostatectomy for unilateral localised prostate cancer. BJU international, 122(6), 970-977. https://doi.org/10.1111/bju.14432

Abstract Objective To describe how clinicians conceptualised equipoise in the PART (Partial prostate Ablation vs Radical prosTatectomy in intermediate‐risk unilateral clinically localised prostate cancer) feasibility study and how this affected rec... Read More about Overcoming difficulties with equipoise to enable recruitment to a randomised controlled trial of partial ablation vs radical prostatectomy for unilateral localised prostate cancer.

Enabling recruitment success in bariatric surgical trials: pilot phase of the By-Band-Sleeve study (2017)
Journal Article
Paramasivan, U. O. B., Rogers, C. A., Welbourn, R., Byrne, J. P., Salter, N., Mahon, D., …on behalf of the By-Band-Sleeve TMG. (2017). Enabling recruitment success in bariatric surgical trials: pilot phase of the By-Band-Sleeve study. International journal of obesity, 41(11), 1654-1661. https://doi.org/10.1038/ijo.2017.153

Background: Randomized controlled trials (RCTs) involving surgical procedures are challenging for recruitment and infrequent in the specialty of bariatrics. The pilot phase of the By-Band-Sleeve study (gastric bypass versus gastric band versus sleev... Read More about Enabling recruitment success in bariatric surgical trials: pilot phase of the By-Band-Sleeve study.

Equipoise across the patient population: optimising recruitment to a randomised controlled trial (2017)
Journal Article
Whybrow, P., Pickard, R., Hrisos, S., & Rapley, T. (2017). Equipoise across the patient population: optimising recruitment to a randomised controlled trial. Trials, 18(1), Article 140. https://doi.org/10.1186/s13063-016-1711-8

Background This paper proposes a novel perspective on the value of qualitative research for improving trial design and optimising recruitment. We report findings from a qualitative study set within the OPEN trial, a surgical randomised controlled tr... Read More about Equipoise across the patient population: optimising recruitment to a randomised controlled trial.

Drug breakthrough offers hope to arthritis sufferers: qualitative analysis of medical research in UK newspapers (2016)
Journal Article
Hanson, H., O'Brien, N., Whybrow, P., Isaacs, J. D., & Rapley, T. (2017). Drug breakthrough offers hope to arthritis sufferers: qualitative analysis of medical research in UK newspapers. Health Expectations, 20(2), 309-320. https://doi.org/10.1111/hex.12460

Background Newspaper stories can impact behaviours, particularly in relation to research participation. It is therefore important to understand the narratives presented and ways in which these are received. Some work to date assumes journalism trans... Read More about Drug breakthrough offers hope to arthritis sufferers: qualitative analysis of medical research in UK newspapers.

Talking About Looking: Three Approaches to Interviewing Carers of People With Rheumatoid Arthritis About Information Seeking (2015)
Journal Article
Lee, R. P., Thompson, B., Whybrow, P., & Rapley, T. (2016). Talking About Looking: Three Approaches to Interviewing Carers of People With Rheumatoid Arthritis About Information Seeking. Qualitative Health Research, 26(9), 1229-1239. https://doi.org/10.1177/1049732315599373

Given the profusion of illness-related information, in this article, we consider how talking about information seeking—and in particular Internet use—is difficult, not because it is necessarily a highly sensitive topic (though it may be), but rather... Read More about Talking About Looking: Three Approaches to Interviewing Carers of People With Rheumatoid Arthritis About Information Seeking.

How Men Manage Bulbar Urethral Stricture by Concealing Urinary Symptoms (2015)
Journal Article
Whybrow, P., Rapley, T., Pickard, R., & Hrisos, S. (2015). How Men Manage Bulbar Urethral Stricture by Concealing Urinary Symptoms. Qualitative Health Research, 25(10), 1435-1442. https://doi.org/10.1177/1049732315573208

In this article, we present findings from research conducted as part of a multi-center surgical trial. Bulbar urethral stricture, a narrowing of the middle urethra, is a common cause of urinary problems in men that can have a profound impact on their... Read More about How Men Manage Bulbar Urethral Stricture by Concealing Urinary Symptoms.