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Poor relationship between exercise capacity and spirometric measurements in patients with more symptomatic heart failure (2005)
Journal Article
Ingle, L., Shelton, R. J., Cleland, J. G., & Clark, A. L. (2005). Poor relationship between exercise capacity and spirometric measurements in patients with more symptomatic heart failure. Journal of cardiac failure, 11(8), 619-623. https://doi.org/10.1016/j.cardfail.2005.06.430

Background: The origin of exercise limitation in patients with chronic heart failure (CHF) is multifactorial, and the relative contributions of different abnormalities may vary with severity of heart failure symptoms. The aim of the current study was... Read More

Clinical trials update from the European Society of Cardiology Heart Failure meeting and the American College of Cardiology: Darbepoetin alfa study, ECHOS, and ASCOT-BPLA (2005)
Journal Article
Cleland, J. G., Coletta, A. P., Clark, A. L., Velavan, P., & Ingle, L. (2005). Clinical trials update from the European Society of Cardiology Heart Failure meeting and the American College of Cardiology: Darbepoetin alfa study, ECHOS, and ASCOT-BPLA. European journal of heart failure, 7(5), 937-939. https://doi.org/10.1016/j.ejheart.2005.07.001

This article provides information and a commentary on landmark trials presented at the European Society of Cardiology Heart Failure meeting held in June 2005, relevant to the pathophysiology, prevention and treatment of heart failure. All reports sho... Read More

The reproducibility and sensitivity of the 6-min walk test in elderly patients with chronic heart failure (2005)
Journal Article
Ingle, L., Shelton, R. J., Rigby, A. S., Nabb, S., Clark, A. L., & Cleland, J. G. (2005). The reproducibility and sensitivity of the 6-min walk test in elderly patients with chronic heart failure. European Heart Journal, 26(17), 1742-1751. https://doi.org/10.1093/eurheartj/ehi259

Aims: The 6-min walk test (6-MWT) is used to estimate functional capacity. However, in elderly patients with chronic heart failure (CHF): (i) 1 year reproducibility of the 6-MWT; (ii) sensitivity of the 6-MWT to self-perceived changes in symptoms of... Read More

Longitudinal myocardial dysfunction in healthy older subjects as a manifestation of cardiac ageing (2005)
Journal Article
Nikitin, N. P., Witte, K. K., Ingle, L., Clark, A. L., Farnsworth, T. A., & Cleland, J. G. (2005). Longitudinal myocardial dysfunction in healthy older subjects as a manifestation of cardiac ageing. Age and ageing, 34(4), 343-349. https://doi.org/10.1093/ageing/afi043

Background: Abnormalities of longitudinal left ventricular (LV) contraction and relaxation may be early markers of cardiac disease. This study was designed to assess the relationship between long-axis LV function and age in healthy subjects. Methods:... Read More