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Detection of doxycycline hyclate and oxymetazoline hydrochloride in pharmaceutical preparations via spectrophotometry and microfluidic paper-based analytical device (μPADs) (2020)
Journal Article
Abdulsattar, J. O., Hadi, H., Richardson, S., Iles, A., & Pamme, N. (2020). Detection of doxycycline hyclate and oxymetazoline hydrochloride in pharmaceutical preparations via spectrophotometry and microfluidic paper-based analytical device (μPADs). Analytica Chimica Acta, 1136, 196-204. https://doi.org/10.1016/j.aca.2020.09.045

There is growing demand for simple to operate, sensitive, on-site quantitative assays to investigate concentrations of drug molecules in pharmaceutical preparations for quality assurance. Here, we report on the development of two colorimetric analysi... Read More about Detection of doxycycline hyclate and oxymetazoline hydrochloride in pharmaceutical preparations via spectrophotometry and microfluidic paper-based analytical device (μPADs).

Paper-based analytical devices for colorimetric detection of: S. aureus and E. coli and their antibiotic resistant strains in milk (2020)
Journal Article
Khan, Q. M., Asif, M., Awan, F. R., Khan, Q. . M., Ngamsom, B., & Pamme, N. (2020). Paper-based analytical devices for colorimetric detection of: S. aureus and E. coli and their antibiotic resistant strains in milk. Analyst, 145(22), 7320-7329. https://doi.org/10.1039/d0an01075h

Animal derived milk which is an important part of human diet due to its high nutritional value not only supports humans but also presents a growth environment for pathogenic bacteria. Milk may become contaminated with bacteria through udder infection... Read More about Paper-based analytical devices for colorimetric detection of: S. aureus and E. coli and their antibiotic resistant strains in milk.

Microfluidic-Based Electrochemical Immunosensing of Ferritin (2020)
Journal Article
Garg, M., Christensen, M. G., Iles, A., Sharma, A. L., Singh, S., & Pamme, N. (2020). Microfluidic-Based Electrochemical Immunosensing of Ferritin. Biosensors, 10(8), Article 91. https://doi.org/10.3390/bios10080091

Ferritin is a clinically important biomarker which reflects the state of iron in the body and is directly involved with anemia. Current methods available for ferritin estimation are generally not portable or they do not provide a fast response. To co... Read More about Microfluidic-Based Electrochemical Immunosensing of Ferritin.

On-chip electrochemical detection of glucose towards the miniaturised quality control of carbohydrate-based radiotracers (2020)
Journal Article
Patinglag, L., Esfahani, M. M. N., Ragunathan, K., He, P., Brown, N. J., Archibald, S. J., …Tarn, M. D. (2020). On-chip electrochemical detection of glucose towards the miniaturised quality control of carbohydrate-based radiotracers. Analyst, 145(14), 4920-4930. https://doi.org/10.1039/c9an01881f

The miniaturisation of positron emission tomography (PET) radiotracer production is facilitating a move towards a dose-on-demand strategy that would enable a stratified approach to patient diagnostics, but while the on-chip synthesis steps have been... Read More about On-chip electrochemical detection of glucose towards the miniaturised quality control of carbohydrate-based radiotracers.

Realisation of a sub-wavelength dimple using a 193 nm wavelength photonic nano jet (2020)
Journal Article
Al-Jarwany, Q. A., Mohammed, A. F., Hamza, A. O., Bouillard, J. S., Adawi, A. M., Pamme, N., & Walton, C. D. (2020). Realisation of a sub-wavelength dimple using a 193 nm wavelength photonic nano jet. Chemical Physics Letters, 750, Article 137400. https://doi.org/10.1016/j.cplett.2020.137400

There are many areas of research that benefit from tight focussing of light. We report experimental and computational results of a laser irradiated silica microsphere, 1 μm diameter localised on an SU-8 substrate. A single pulse from an ArF excimer l... Read More about Realisation of a sub-wavelength dimple using a 193 nm wavelength photonic nano jet.

Biosensor for determining average iron content of ferritin by measuring its optical dispersion (2020)
Journal Article
Gupta, R., Alamrani, N. A., Greenway, G. M., Pamme, N., & Goddard, N. J. (2020). Biosensor for determining average iron content of ferritin by measuring its optical dispersion. Proceedings of SPIE, 11235, https://doi.org/10.1117/12.2542162

© 2020 SPIE. Average iron content of ferritin has a potential to serve as a biomarker for early identification of high-risk trauma patients at point-of-care (PoC). Appropriate therapies can then be administered to reduce morbidity and mortality. Curr... Read More about Biosensor for determining average iron content of ferritin by measuring its optical dispersion.

FISH and chips: a review of microfluidic platforms for FISH analysis (2020)
Journal Article
Rodriguez-Mateos, P., Azevedo, N. F., Almeida, C., & Pamme, N. (2020). FISH and chips: a review of microfluidic platforms for FISH analysis. Medical Microbiology and Immunology, 209(3), 373-391. https://doi.org/10.1007/s00430-019-00654-1

Fluorescence in situ hybridization (FISH) allows visualization of specific nucleic acid sequences within an intact cell or a tissue section. It is based on molecular recognition between a fluorescently labeled probe that penetrates the cell membrane... Read More about FISH and chips: a review of microfluidic platforms for FISH analysis.