All Outputs (10)

Prevalence and severity of differing dimensions of breathlessness among elderly males in the population (2021)
Journal Article
Olsson, M., Currow, D. C., Johnson, M. J., Sandberg, J., Engström, G., & Ekstrom, M. (2022). Prevalence and severity of differing dimensions of breathlessness among elderly males in the population. ERJ Open Research, 8(1), https://doi.org/10.1183/23120541.00553-2021

Breathlessness is common in the general population. Existing data were obtained primarily with the uni-dimensional modified Medical Research Council breathlessness scale (mMRC) that does not assess intensities of unpleasantness nor physical, emotiona... Read More about Prevalence and severity of differing dimensions of breathlessness among elderly males in the population.

Breathlessness dimensions association with physical and mental quality of life – the population based VASCOL study of elderly men (2021)
Journal Article
Cristea, L., Olsson, M., Currow, D., Johnson, M., Sandberg, J., & Ekström, M. (2021). Breathlessness dimensions association with physical and mental quality of life – the population based VASCOL study of elderly men. BMJ Open Respiratory Research, 8(1), Article e000990. https://doi.org/10.1136/bmjresp-2021-000990

Background Breathlessness is a multidimensional symptom prevalent in elderly affecting many aspects of life. We aimed to determine how different dimensions of breathlessness are associated with physical and mental quality of life (QoL) in elderly men... Read More about Breathlessness dimensions association with physical and mental quality of life – the population based VASCOL study of elderly men.

Health service utilisation associated with chronic breathlessness: random population sample (2021)
Journal Article
Currow, D. C., Chang, S., Ekström, M., Luckett, T., Kochovska, S., Hay, P., …Johnson, M. J. (2021). Health service utilisation associated with chronic breathlessness: random population sample. ERJ Open Research, 7(4), Article 00415-2021. https://doi.org/10.1183/23120541.00415-2021

Background Most health service utilisation studies are of people with specific diagnoses or demographic characteristics, and rarely of specific chronic symptoms. The aim of this study was to establish whether population-level health service utilisati... Read More about Health service utilisation associated with chronic breathlessness: random population sample.

Performance status and trial site-level factors are associated with missing data in palliative care trials: An individual participant-level data analysis of 10 phase 3 trials (2021)
Journal Article
Hussain, J. A., White, I. R., Johnson, M. J., Bland, M., & Currow, D. C. (2021). Performance status and trial site-level factors are associated with missing data in palliative care trials: An individual participant-level data analysis of 10 phase 3 trials. Palliative medicine, https://doi.org/10.1177/02692163211040970

Background: Missing data compromise the internal and external validity of trial findings, however there is limited evidence on how best to reduce missing data in palliative care trials. Aim: To assess the association between participant and site leve... Read More about Performance status and trial site-level factors are associated with missing data in palliative care trials: An individual participant-level data analysis of 10 phase 3 trials.

VAScular and Chronic Obstructive Lung disease (VASCOL): A longitudinal study on morbidity, symptoms and quality of life among older men in Blekinge county, Sweden (2021)
Journal Article
Olsson, M., Engström, G., Currow, D. C., Johnson, M., Sandberg, J., & Ekström, M. (2021). VAScular and Chronic Obstructive Lung disease (VASCOL): A longitudinal study on morbidity, symptoms and quality of life among older men in Blekinge county, Sweden. BMJ open, 11(7), https://doi.org/10.1136/bmjopen-2020-046473

Purpose Despite data showing breathlessness to be more prevalent in older adults, we have little detail about the severity or multidimensional characteristics of breathlessness and other self-reported measures (such as quality of life and other cardi... Read More about VAScular and Chronic Obstructive Lung disease (VASCOL): A longitudinal study on morbidity, symptoms and quality of life among older men in Blekinge county, Sweden.

Professionals’, patients’ and families’ views on the use of opioids for chronic breathlessness: A systematic review using the framework method and pillar process (2021)
Journal Article
Reedy, F., Pearson, M., Greenley, S., Clark, J., Currow, D. C., Bajwah, S., …Johnson, M. J. (in press). Professionals’, patients’ and families’ views on the use of opioids for chronic breathlessness: A systematic review using the framework method and pillar process. Palliative medicine, https://doi.org/10.1177/02692163211032114

Background: In combination with non-pharmacological interventions, opioids may safely reduce chronic breathlessness in patients with severe illness. However, implementation in clinical practice varies. Aim: To synthesise the published literature rega... Read More about Professionals’, patients’ and families’ views on the use of opioids for chronic breathlessness: A systematic review using the framework method and pillar process.

Comparing functional decline and distress from symptoms in people with thoracic life-limiting illnesses: Lung cancers and non-malignant end-stage respiratory diseases (2021)
Journal Article
Barnes-Harris, M., Allingham, S., Morgan, D., Ferreira, D., Johnson, M. J., Eagar, K., & Currow, D. (2021). Comparing functional decline and distress from symptoms in people with thoracic life-limiting illnesses: Lung cancers and non-malignant end-stage respiratory diseases. Thorax, 76(10), 989-995. https://doi.org/10.1136/thoraxjnl-2020-216039

© Author(s) (or their employer(s)) 2021. No commercial re-use. See rights and permissions. Published by BMJ. Background: Malignant and non-malignant respiratory diseases account for >4.6 million deaths annually worldwide. Despite similar symptom burd... Read More about Comparing functional decline and distress from symptoms in people with thoracic life-limiting illnesses: Lung cancers and non-malignant end-stage respiratory diseases.

Indications and patterns of use of benzodiazepines and opioids in severe interstitial lung disease: a population-based longitudinal study (2021)
Journal Article
Genberg, J., Davies, J. M., Ahmadi, Z., Currow, D., Johnson, M. J., Tanash, H., …Ekström, M. (2021). Indications and patterns of use of benzodiazepines and opioids in severe interstitial lung disease: a population-based longitudinal study. ERJ Open Research, 7(1), 1-7. https://doi.org/10.1183/23120541.00716-2020

Background: Despite evidence that opioids might relieve chronic breathlessness, physicians may still be reluctant to prescribe them due to safety concerns. By contrast, benzodiazepine (BDZ) prescribing often seeks to reduce chronic breathlessness des... Read More about Indications and patterns of use of benzodiazepines and opioids in severe interstitial lung disease: a population-based longitudinal study.

A cluster randomised trial of a Needs Assessment Tool for adult Cancer patients and their carers (NAT-C) in primary care: A feasibility study (2021)
Journal Article
Clark, J., Amoakwa, E., Wright-Hughes, A., Blenkinsopp, J., Currow, D. C., Meads, D., …Johnson, M. (2021). A cluster randomised trial of a Needs Assessment Tool for adult Cancer patients and their carers (NAT-C) in primary care: A feasibility study. PLoS ONE, 16(1), Article e0245647. https://doi.org/10.1371/journal.pone.0245647

Background People with cancer often have unidentified symptoms and social care needs. The Needs Assessment Tool-Cancer (NAT-C) is a validated, structured method of assessing patient/ carer concerns and prompting action, to address unmet need. Aims As... Read More about A cluster randomised trial of a Needs Assessment Tool for adult Cancer patients and their carers (NAT-C) in primary care: A feasibility study.

A feasibility cluster randomised controlled trial of a paramedic-administered breathlessness management intervention for acute-on-chronic breathlessness (BREATHE): Study protocol (2021)
Journal Article
Northgraves, M., Cohen, J., Allgar, V., Currow, D., Hart, S., Hird, K., …Hutchinson, A. (2021). A feasibility cluster randomised controlled trial of a paramedic-administered breathlessness management intervention for acute-on-chronic breathlessness (BREATHE): Study protocol. ERJ Open Research, 7(1), Article 00955-2020. https://doi.org/10.1183/23120541.00955-2020

Introduction: Chronic breathlessness, persistent and disabling despite optimal treatment of underlying causes, is a prevalent and frightening symptom and is associated with many emergency presentations and admission to hospital. Breathlessness manage... Read More about A feasibility cluster randomised controlled trial of a paramedic-administered breathlessness management intervention for acute-on-chronic breathlessness (BREATHE): Study protocol.