Early mortality from colorectal cancer in England: A retrospective observational study of the factors associated with death in the first year after diagnosis

Downing, A.; Aravani, A.; MacLeod, U.; Oliver, S.; Finan, P. J.; Thomas, J. D.; Quirke, P.; Wilkinson, J. R.; Morris, E. J.A.

doi:10.1038/bjc.2012.585

The expanding role of primary care in cancer control (2015)
Journal Article
Rubin, G., Berendsen, A., Crawford, S. M., Dommett, R., Earle, C., Emery, J., …Zimmermann, C. (2015). The expanding role of primary care in cancer control. The lancet oncology, 16(12), 1231-1272. https://doi.org/10.1016/S1470-2045%2815%2900205-3

© 2015 Elsevier Ltd. The nature of cancer control is changing, with an increasing emphasis, fuelled by public and political demand, on prevention, early diagnosis, and patient experience during and after treatment. At the same time, primary care is i... Read More about The expanding role of primary care in cancer control.

Low cancer suspicion following experience of a cancer 'warning sign' (2015)
Journal Article
Whitaker, K. L., Winstanley, K., Macleod, U., Scott, S. E., & Wardle, J. (2015). Low cancer suspicion following experience of a cancer 'warning sign'. European Journal of Cancer, 51(16), 2473-2479. https://doi.org/10.1016/j.ejca.2015.07.014

© 2015 The Authors. Published by Elsevier Ltd. Aim Lower socioeconomic status (SES) is associated with a higher risk of late-stage cancer diagnosis. A number of explanations have been advanced for this, but one which has attracted recent attention is... Read More about Low cancer suspicion following experience of a cancer 'warning sign'.

Risk factors for emergency presentation with lung and colorectal cancers: A systematic review (2015)
Journal Article
Mitchell, E. D., Pickwell-Smith, B., & Macleod, U. (2015). Risk factors for emergency presentation with lung and colorectal cancers: A systematic review. BMJ open, 5(4), Article e006965. https://doi.org/10.1136/bmjopen-2014-006965

© 2015, BMJ. All rights reserved. Objective: To identify patient and practitioner factors that influence cancer diagnosis via emergency presentation (EP). Design: Systematic review. Data sources: MEDLINE, EMBASE, CINAHL, EBM Reviews, Science and Soci... Read More about Risk factors for emergency presentation with lung and colorectal cancers: A systematic review.

Core intended learning outcomes for tackling health inequalities in undergraduate medicine Curriculum development (2015)
Journal Article
Williamson, A. E., Ayres, R., Allen, J., & Macleod, U. (2015). Core intended learning outcomes for tackling health inequalities in undergraduate medicine Curriculum development. BMC Medical Education, 15(1), Article 66. https://doi.org/10.1186/s12909-015-0342-1

© 2015 Williamson et al.; licensee BioMed Central. Background: Despite there being a concerted effort in recent years to influence what doctors can do to tackle health inequalities in the UK, there has been limited policy focus on what undergraduate... Read More about Core intended learning outcomes for tackling health inequalities in undergraduate medicine Curriculum development.

GPs' perceptions and experiences of public awareness campaigns for cancer: A qualitative enquiry (2015)
Journal Article
Green, T., Atkin, K., & Macleod, U. (2016). GPs' perceptions and experiences of public awareness campaigns for cancer: A qualitative enquiry. Health Expectations, 19(2), 377-387. https://doi.org/10.1111/hex.12362

© 2016 John Wiley & Sons Ltd. Background: Public awareness campaigns for cancer are used to alert the UK population to symptoms which, if experienced, should be discussed with their general practitioner (GP). More timely diagnosis of cancer is assu... Read More about GPs' perceptions and experiences of public awareness campaigns for cancer: A qualitative enquiry.

Correction: Attributions of cancer 'alarm' symptoms in a community sample (2015)
Journal Article
Whitaker, K. L., Scott, S. E., Winstanley, K., Macleod, U., & Wardle, J. (2015). Correction: Attributions of cancer 'alarm' symptoms in a community sample. PLoS ONE, 10(3), Article e0118418. https://doi.org/10.1371/journal.pone.0118418

In Table 1, the (N) value in the “*Cough or hoarseness” column in the last row is incorrectly recorded as 1469. The (N) value should be 149. Please see the corrected Table 1 here.

Embedding electronic decision-support tools for suspected cancer in primary care: a qualitative study of GPs' experiences (2015)
Journal Article
Dikomitis, L., Green, T., & Macleod, U. (2015). Embedding electronic decision-support tools for suspected cancer in primary care: a qualitative study of GPs' experiences. Primary health care research & development, 16(6), 548-555. https://doi.org/10.1017/S1463423615000109

Aim: The purpose of this evaluation was to obtain views from general practitioners (GPs) who piloted the electronic risk assessment tools (eRATs) for suspected lung or colorectal cancer. We wanted to find out whether GPs were able to integrate these... Read More about Embedding electronic decision-support tools for suspected cancer in primary care: a qualitative study of GPs' experiences.

The role of primary care in cancer diagnosis via emergency presentation: qualitative synthesis of significant event reports (2015)
Journal Article
Mitchell, E. D., Rubin, G., Merriman, L., & Macleod, U. (2015). The role of primary care in cancer diagnosis via emergency presentation: qualitative synthesis of significant event reports. The British Journal of Cancer, 112(S1), S50-S56. https://doi.org/10.1038/bjc.2015.42

Background: Patients diagnosed with cancer in the context of an emergency presentation (EP) have poorer outcomes. It is often assumed that such patients present to the emergency department without consulting their general practitioner (GP). Little w... Read More about The role of primary care in cancer diagnosis via emergency presentation: qualitative synthesis of significant event reports.

Cancer detection in primary care: Insights from general practitioners (2015)
Journal Article
Green, T., Atkin, K., & Macleod, U. (2015). Cancer detection in primary care: Insights from general practitioners. The British Journal of Cancer, 112, S41-S49. https://doi.org/10.1038/bjc.2015.41

© 2015 Cancer Research UK. Background: General practitioners (GPs) have a key role in cancer detection as the usual first point of contact for patients with potential cancer symptoms. Nevertheless, there is limited work that investigates their percep... Read More about Cancer detection in primary care: Insights from general practitioners.

Is increased time to diagnosis and treatment in symptomatic cancer associated with poorer outcomes? Systematic review (2015)
Journal Article
Neal, R. D., Tharmanathan, P., France, B., Din, N. U., Cotton, S., Fallon-Ferguson, J., …Emery, J. (2015). Is increased time to diagnosis and treatment in symptomatic cancer associated with poorer outcomes? Systematic review. The British Journal of Cancer, 112, S92-S107. https://doi.org/10.1038/bjc.2015.48

© 2015 Cancer Research UK. Background: It is unclear whether more timely cancer diagnosis brings favourable outcomes, with much of the previous evidence, in some cancers, being equivocal. We set out to determine whether there is an association betwee... Read More about Is increased time to diagnosis and treatment in symptomatic cancer associated with poorer outcomes? Systematic review.

Help seeking for cancer 'alarm' symptoms: A qualitative interview study of primary care patients in the UK (2015)
Journal Article
Whitaker, K. L., Macleod, U., Winstanley, K., Scott, S. E., & Wardle, J. (2015). Help seeking for cancer 'alarm' symptoms: A qualitative interview study of primary care patients in the UK. The British journal of general practice : the journal of the Royal College of General Practitioners, 65(631), e96-e105. https://doi.org/10.3399/bjgp15X683533

©British Journal of General Practice Background: Delay in help seeking for cancer 'alarm' symptoms has been identified as a contributor to delayed diagnosis. Aim: To understand people's help-seeking decision making for cancer alarm symptoms, without... Read More about Help seeking for cancer 'alarm' symptoms: A qualitative interview study of primary care patients in the UK.

Attributions of cancer 'alarm' symptoms in a community sample (2014)
Journal Article
Whitaker, K. L., Scott, S. E., Winstanley, K., Macleod, U., & Wardle, J. (2014). Attributions of cancer 'alarm' symptoms in a community sample. PLoS ONE, 9(12), Article e114028. https://doi.org/10.1371/journal.pone.0114028

© 2014 Whitaker et al. Background: Attribution of early cancer symptoms to a non-serious cause may lead to longer diagnostic intervals. We investigated attributions of potential cancer 'alarm' and non-alarm symptoms experienced in everyday life in a... Read More about Attributions of cancer 'alarm' symptoms in a community sample.

Exploring GPs' experiences of using diagnostic tools for cancer: A qualitative study in primary care (2014)
Journal Article
Green, T., Martins, T., Hamilton, W., Rubin, G., Elliott, K., & Macleod, U. (2015). Exploring GPs' experiences of using diagnostic tools for cancer: A qualitative study in primary care. Family practice, 32(1), 101-105. https://doi.org/10.1093/fampra/cmu081

© The Author 2014. Background. The UK has an estimated 5-10 000 extra cancer deaths each year when compared to other European countries and diagnostic delays are thought to make a significant contribution to this. One of the initiatives in England in... Read More about Exploring GPs' experiences of using diagnostic tools for cancer: A qualitative study in primary care.

Palliative care among heart failure patients in primary care: A comparison to cancer patients using english family practice data (2014)
Journal Article
Gadoud, A., Kane, E., Macleod, U., Ansell, P., Oliver, S., & Johnson, M. (2014). Palliative care among heart failure patients in primary care: A comparison to cancer patients using english family practice data. PLoS ONE, 9(11), Article e113188. https://doi.org/10.1371/journal.pone.0113188

© 2014 Gadoud et al. Introduction: Patients with heart failure have a significant symptom burden and other palliative care needs often over a longer period than patients with cancer. It is acknowledged that this need may be unmet but by how much has... Read More about Palliative care among heart failure patients in primary care: A comparison to cancer patients using english family practice data.

Patient, carer and professional perspectives on barriers and facilitators to quality care in advanced heart failure (2014)
Journal Article
Browne, S., Macdonald, S., May, C. R., Macleod, U., & Mair, F. S. (2014). Patient, carer and professional perspectives on barriers and facilitators to quality care in advanced heart failure. PLoS ONE, 9(3), Article e93288. https://doi.org/10.1371/journal.pone.0093288

Background: Those with advanced heart failure (HF) experience high levels of morbidity and mortality, similar to common cancers. However, there remains evidence of inequity of access to palliative care services compared to people with cancer. This st... Read More about Patient, carer and professional perspectives on barriers and facilitators to quality care in advanced heart failure.

Time-to-diagnosis and symptoms of myeloma, lymphomas and leukaemias: A report from the Haematological malignancy Research Network (2013)
Journal Article
Howell, D. A., Smith, A. G., Jack, A., Patmore, R., Macleod, U., Mironska, E., & Roman, E. (2013). Time-to-diagnosis and symptoms of myeloma, lymphomas and leukaemias: A report from the Haematological malignancy Research Network. BMC Hematology, 13(1), Article 9. https://doi.org/10.1186/2052-1839-13-9

© 2013 Howell et al. Background: Prior to diagnosis, patients with haematological cancers often have multiple primary care consultations, resulting in diagnostic delay. They are less likely to be referred urgently to hospital and often present as eme... Read More about Time-to-diagnosis and symptoms of myeloma, lymphomas and leukaemias: A report from the Haematological malignancy Research Network.

Predictors of anxiety and depression in people with colorectal cancer (2013)
Journal Article
Gray, N. M., Hall, S. J., Browne, S., Johnston, M., Lee, A. J., Macleod, U., …Campbell, N. C. (2014). Predictors of anxiety and depression in people with colorectal cancer. Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 22(2), 307-314. https://doi.org/10.1007/s00520-013-1963-8

Background: People living with colorectal cancer are at risk of anxiety and depression. We investigated what factors were most highly associated with these. Methods: Four hundred and ninety-six people with colorectal cancer completed the Hospital Anx... Read More about Predictors of anxiety and depression in people with colorectal cancer.

Understanding diagnosis of lung cancer in primary care: qualitative synthesis of significant event audit reports (2013)
Journal Article
Mitchell, E. D., Rubin, G., & Macleod, U. (2013). Understanding diagnosis of lung cancer in primary care: qualitative synthesis of significant event audit reports. The British journal of general practice : the journal of the Royal College of General Practitioners, 63(606), e37-e46. https://doi.org/10.3399/bjgp13X660760

Background Most lung cancers present symptomatically, but the pathway to diagnosis in primary care can be complex and is poorly understood. Significant event audit (SEA) is a quality improvement technique widely used in UK general practice. Aim To ga... Read More about Understanding diagnosis of lung cancer in primary care: qualitative synthesis of significant event audit reports.

Developing a community-based intervention to improve quality of life in people with colorectal cancer: A complex intervention development study (2013)
Journal Article
Gray, N. M., Allan, J. L., Murchie, P., Browne, S., Hall, S., Hubbard, G., …Campbell, N. C. (2013). Developing a community-based intervention to improve quality of life in people with colorectal cancer: A complex intervention development study. BMJ open, 3(4), Article e002596. https://doi.org/10.1136/bmjopen-2013-002596

Objectives: To develop and pilot a theory and evidence-based intervention to improve quality of life (QoL) in people with colorectal cancer. Design: A complex intervention development study. Setting: North East Scotland and Glasgow. Participants: Sem... Read More about Developing a community-based intervention to improve quality of life in people with colorectal cancer: A complex intervention development study.

Early mortality from colorectal cancer in England: A retrospective observational study of the factors associated with death in the first year after diagnosis (2013)
Journal Article
Downing, A., Aravani, A., MacLeod, U., Oliver, S., Finan, P. J., Thomas, J. D., …Morris, E. J. (2013). Early mortality from colorectal cancer in England: A retrospective observational study of the factors associated with death in the first year after diagnosis. The British Journal of Cancer, 108(3), 681-685. https://doi.org/10.1038/bjc.2012.585

Background: The United Kingdom performs poorly in international comparisons of colorectal cancer survival with much of the deficit owing to high numbers of deaths close to the time of diagnosis. This retrospective cohort study investigates the patien... Read More about Early mortality from colorectal cancer in England: A retrospective observational study of the factors associated with death in the first year after diagnosis.

All Outputs (80)