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A practical microwave method for the synthesis of fluoromethy 4-methylbenzenesulfonate in tert-amyl alcohol (2018)
Journal Article
Brocklesby, K. L., Waby, J. S., Cawthorne, C., & Smith, G. D. (2018). A practical microwave method for the synthesis of fluoromethy 4-methylbenzenesulfonate in tert-amyl alcohol. Tetrahedron letters; the international organ for the rapid publication of preliminary communications in organic chemistry, 59(17), 1635-1637. https://doi.org/10.1016/j.tetlet.2018.03.039

Fluorine substitution is an established tool in medicinal chemistry to favourably alter the molecular properties of a lead compound of interest. However, gaps still exist in the library of synthetic methods for accessing certain fluorine-substituted... Read More about A practical microwave method for the synthesis of fluoromethy 4-methylbenzenesulfonate in tert-amyl alcohol.