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All Outputs (28)

Effect of spirometry on intra-thoracic pressures (2018)
Journal Article
Tiller, N. B., & Simpson, A. J. (2018). Effect of spirometry on intra-thoracic pressures. BMC research notes, 11(1), Article 110. https://doi.org/10.1186/s13104-018-3217-9

Objective Due to the high intra-thoracic pressures associated with forced vital capacity manoeuvres, spirometry is contraindicated for vulnerable patients. However, the typical pressure response to spirometry has not been reported. Eight healthy, re... Read More about Effect of spirometry on intra-thoracic pressures.

Exercise-induced dehydration alters pulmonary function but does not modify airway responsiveness to dry air in athletes with mild asthma (2017)
Journal Article
Simpson, A. J., Romer, L. M., & Kippelen, P. (2017). Exercise-induced dehydration alters pulmonary function but does not modify airway responsiveness to dry air in athletes with mild asthma. Journal of Applied Physiology, 122(5), 1329-1335. https://doi.org/10.1152/japplphysiol.01114.2016

Local airway water loss is the main physiological trigger for exercise-induced bronchoconstriction (EIB). Our aim was to investigate the effects of whole body water loss on airway responsiveness and pulmonary function in athletes with mild asthma and... Read More about Exercise-induced dehydration alters pulmonary function but does not modify airway responsiveness to dry air in athletes with mild asthma.

Perspectives of patients and healthcare professionals on mHealth for asthma self-management (2017)
Journal Article
Simpson, A. J., Honkoop, P. J., Kennington, E., Snoeck-Stroband, J., Smith, I., East, J., …Fowler, S. (2017). Perspectives of patients and healthcare professionals on mHealth for asthma self-management. European respiratory journal, 49(5), Article ARTN 1601966. https://doi.org/10.1183/13993003.01966-2016

Copyright ©ERS 2017. Mobile healthcare (mHealth) has the potential to revolutionise the self-management of long-term medical conditions such as asthma. A user-centred design is integral if mHealth is to be embraced by patients and healthcare professi... Read More about Perspectives of patients and healthcare professionals on mHealth for asthma self-management.

MyAirCoach: The use of home-monitoring and mHealth systems to predict deterioration in asthma control and the occurrence of asthma exacerbations; Study protocol of an observational study (2017)
Journal Article
Honkoop, P. J., Simpson, A., Bonini, M., Snoeck-Stroband, J. B., Meah, S., Chung, K. F., …Sont, J. K. (2017). MyAirCoach: The use of home-monitoring and mHealth systems to predict deterioration in asthma control and the occurrence of asthma exacerbations; Study protocol of an observational study. BMJ open, 7(1), Article ARTN e013935. https://doi.org/10.1136/bmjopen-2016-013935

© Published by the BMJ Publishing Group Limited. Introduction Asthma is a variable lung condition whereby patients experience periods of controlled and uncontrolled asthma symptoms. Patients who experience prolonged periods of uncontrolled asthma hav... Read More about MyAirCoach: The use of home-monitoring and mHealth systems to predict deterioration in asthma control and the occurrence of asthma exacerbations; Study protocol of an observational study.

A standard, single dose of inhaled terbutaline attenuates hyperpnea-induced bronchoconstriction and mast cell activation in athletes (2016)
Journal Article
Simpson, A. J., Bood, J. R., Anderson, S. D., Romer, L. M., Dahlén, B., Dahlén, S. E., & Kippelen, P. (2016). A standard, single dose of inhaled terbutaline attenuates hyperpnea-induced bronchoconstriction and mast cell activation in athletes. Journal of Applied Physiology, 120(9), 1011-1017. https://doi.org/10.1152/japplphysiol.00700.2015

Release of bronchoactive mediators from mast cells during exercise hyperpnea is a key factor in the pathophysiology of exercise-induced bronchoconstriction (EIB). Our aim was to investigate the effect of a standard, single dose of an inhaled β 2 -adr... Read More about A standard, single dose of inhaled terbutaline attenuates hyperpnea-induced bronchoconstriction and mast cell activation in athletes.

Self-reported symptoms after induced and inhibited bronchoconstriction in athletes (2015)
Journal Article
Simpson, A. J., Romer, L. M., & Kippelen, P. (2015). Self-reported symptoms after induced and inhibited bronchoconstriction in athletes. Medicine and Science in Sports and Exercise, 47(10), 2005-2013. https://doi.org/10.1249/mss.0000000000000646

Purpose: A change in the perception of respiratory symptoms after treatment with inhaled beta2 agonists is often used to aid diagnosis of exercise-induced bronchoconstriction (EIB). Our aim was to test the association between subjective ratings of r... Read More about Self-reported symptoms after induced and inhibited bronchoconstriction in athletes.

Effect of terbutaline on hyperpnoea-induced bronchoconstriction and urinary club cell protein 16 in athletes (2013)
Journal Article
Simpson, A. J., Simpson, A. J., Tufvesson, E., Tufvesson, E., Anderson, S. D., Anderson, S. D., …Kippelen, P. (2013). Effect of terbutaline on hyperpnoea-induced bronchoconstriction and urinary club cell protein 16 in athletes. Journal of Applied Physiology, 115(10), 1450-1456. https://doi.org/10.1152/japplphysiol.00716.2013

Repeated injury of the airway epithelium caused by hyperpnoea of poorly conditioned air has been proposed as a key factor in the pathogenesis of exercise-induced bronchoconstriction (EIB) in athletes. In animals, the short-acting β2-agonist terbutali... Read More about Effect of terbutaline on hyperpnoea-induced bronchoconstriction and urinary club cell protein 16 in athletes.