All Outputs (61)

A label-free aptamer-based nanogap capacitive biosensor with greatly diminished electrode polarization effects (2019)
Journal Article
Ghobaei Namhil, Z., Kemp, C., Verrelli, E., Iles, A., Pamme, N., Adawi, A. M., & Kemp, N. (2019). A label-free aptamer-based nanogap capacitive biosensor with greatly diminished electrode polarization effects. Physical chemistry chemical physics : PCCP, 21(2), 681-691. https://doi.org/10.1039/c8cp05510f

A significant impediment to the use of impedance spectroscopy in bio-sensing is the electrode polarization effect that arises from the movement of free ions to the electrode-solution interface, forming an electrical double layer (EDL). The EDL screen... Read More about A label-free aptamer-based nanogap capacitive biosensor with greatly diminished electrode polarization effects.

Microcapsules as assay compartments formed through layer-by-layer deposition (2018)
Journal Article
Alorabi, A. Q., Tarn, M. D., Thomas, M., Paunov, V. N., & Pamme, N. (2018). Microcapsules as assay compartments formed through layer-by-layer deposition. Analytical Methods, 10(44), 5335-5340. https://doi.org/10.1039/c8ay02012d

We investigate the potential of using microcapsules, generated through layer-by-layer assembly, as reaction compartments for bioassays. A streptavidin-biotin and an esterase-fluorescein diacetate (FDA) assay were employed for proof-of-concept. Strept... Read More about Microcapsules as assay compartments formed through layer-by-layer deposition.

Plastic scintillator-based microfluidic devices for miniaturized detection of Positron Emission Tomography radiopharmaceuticals (2018)
Journal Article
Tarn, M. D., Kızılyer, N. Y., Esfahani, M. M. N., Joshi, P., Brown, N. J., Pamme, N., …Archibald, S. J. (2018). Plastic scintillator-based microfluidic devices for miniaturized detection of Positron Emission Tomography radiopharmaceuticals. Chemistry: a European journal, 24(52), 13749-13753. https://doi.org/10.1002/chem.201802395

A miniaturized radio-HPLC detector has been developed comprising a microfluidic device fabricated from plastic scintillator in combination with a silicon photomultiplier light sensor, and tested with samples containing a positron-emitting radionuclid... Read More about Plastic scintillator-based microfluidic devices for miniaturized detection of Positron Emission Tomography radiopharmaceuticals.

Correction: On-chip polyelectrolyte coating onto magnetic droplets – towards continuous flow assembly of drug delivery capsules (2017)
Journal Article
Alorabi, A. Q., Tarn, M. D., Gómez-Pastora, J., Bringas, E., Ortiz, I., Paunov, V. N., & Pamme, N. (2017). Correction: On-chip polyelectrolyte coating onto magnetic droplets – towards continuous flow assembly of drug delivery capsules. Lab on a chip, 17(22), 3934. https://doi.org/10.1039/c7lc90110k

Correction for ‘On-chip polyelectrolyte coating onto magnetic droplets – towards continuous flow assembly of drug delivery capsules’ by Ali Q. Alorabi et al., Lab Chip, 2017, DOI: 10.1039/c7lc00918f.

Fabrication of tailorable pH responsive cationic amphiphilic microgels on a microfluidic device for drug release (2017)
Journal Article
Lu, B., Tarn, M. D., Pamme, N., & Georgiou, T. K. (2018). Fabrication of tailorable pH responsive cationic amphiphilic microgels on a microfluidic device for drug release. Journal of Polymer Science Part A: Polymer Chemistry, 56(1), 59-66. https://doi.org/10.1002/pola.28860

Cationic, amphiphilic microgels of differing compositions based on hydrophilic, pH, and thermoresponsive 2-(dimethylamino)ethyl methacrylate (DMAEMA) and hydrophobic, nonionic n-butyl acrylate (BuA) are synthesized using a lab-on-a-chip device. Hydro... Read More about Fabrication of tailorable pH responsive cationic amphiphilic microgels on a microfluidic device for drug release.

On-chip polyelectrolyte coating onto magnetic droplets – towards continuous flow assembly of drug delivery capsules (2017)
Journal Article
Alorabi, A. Q., Tarn, M. D., Gómez-Pastora, J., Bringas, E., Ortiz, I., Paunov, V. N., & Pamme, N. (2017). On-chip polyelectrolyte coating onto magnetic droplets – towards continuous flow assembly of drug delivery capsules. Lab on a chip, 17(22), 3785-3795. https://doi.org/10.1039/c7lc00918f

Polyelectrolyte (PE) microcapsules for drug delivery are typically fabricated via layer-by-layer (LbL) deposition of PE layers of alternating charge on sacrificial template microparticles, which usually requires multiple incubation and washing steps... Read More about On-chip polyelectrolyte coating onto magnetic droplets – towards continuous flow assembly of drug delivery capsules.

A microfluidic device for rapid screening of E. coli O157:H7 based on IFAST and ATP bioluminescence assay for water analysis (2017)
Journal Article
Ngamsom, B., Truyts, A., Fourie, L., Kumar, S., Tarn, M. D., Iles, A., …Pamme, N. (2017). A microfluidic device for rapid screening of E. coli O157:H7 based on IFAST and ATP bioluminescence assay for water analysis. Chemistry: a European journal, 23(52), 12754-12757. https://doi.org/10.1002/chem.201703487

© 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim We present a simple microfluidic system for rapid screening of Escherichia coli (E. coli) O157:H7 employing the specificity of immunomagnetic separation (IMS) via immiscible filtration assisted by s... Read More about A microfluidic device for rapid screening of E. coli O157:H7 based on IFAST and ATP bioluminescence assay for water analysis.

Definition of a magnetic susceptibility of conglomerates with magnetite particles. Particularities of defining single particle susceptibility (2017)
Journal Article
Sandulyak, A. A., Sandulyak, A. V., Ershova, V., Pamme, N., Ngmasom, B., & Iles, A. (2017). Definition of a magnetic susceptibility of conglomerates with magnetite particles. Particularities of defining single particle susceptibility. Journal of Magnetism and Magnetic Materials, 441, 724-734. https://doi.org/10.1016/j.jmmm.2017.06.027

Data of a magnetic susceptibility of ferro-and the ferrimagnetic particles of many technogenic, natural, special media are especially demanded for the solution of various tasks connected with purposeful magnetic impact on these particles. One of prod... Read More about Definition of a magnetic susceptibility of conglomerates with magnetite particles. Particularities of defining single particle susceptibility.

Magnetic particles-based chemiluminescence immunoassay for progesterone determination (2017)
Journal Article
Phakthong, W., Greenway, G. M., Pamme, N., Liawruangrath, B., & Liawruangrath, S. (2017). Magnetic particles-based chemiluminescence immunoassay for progesterone determination. Wārasān Khana Witthayāsāt, Mahāwitthayālai Chīang Mai = Journal of the Science Faculty of Chiang Mai University / Mahāwitthayālai Chīang Mai, 44(1), 215-223

© 2017, Chiang Mai University. All rights reserved. A magnetic particles-based chemiluminescence immunoassay was investigated for progesterone detection by using luminometer. In this work, progesterone was determined based on the competitive binding... Read More about Magnetic particles-based chemiluminescence immunoassay for progesterone determination.

Monolith-based68Ga processing: A new strategy for purification to facilitate direct radiolabelling methods (2016)
Journal Article
He, P., Burke, B. P., Clemente, G. S., Brown, N., Pamme, N., & Archibald, S. J. (2016). Monolith-based68Ga processing: A new strategy for purification to facilitate direct radiolabelling methods. Reaction Chemistry and Engineering, 1(4), 361-365. https://doi.org/10.1039/c6re00081a

The post-processing of68Ga generator eluate by means of a novel high capacity cation-exchange silica monolith column has been validated in this work. Quantitative release of a purified68Ga solution in high concentration can be achieved using weak aci... Read More about Monolith-based68Ga processing: A new strategy for purification to facilitate direct radiolabelling methods.

Sample introduction interface for on-chip nucleic acid-based analysis of Helicobacter pylori from stool samples (2016)
Journal Article
Esfahani, M. M. N., Shaw, K. J., Esfahani, M. M., Kemp, C., Tarn, M. D., Melling, L., …Mosley, O. (2016). Sample introduction interface for on-chip nucleic acid-based analysis of Helicobacter pylori from stool samples. Lab on a chip, 16(11), 2108-2115. https://doi.org/10.1039/c6lc00228e

Despite recent advances in microfluidic-based integrated diagnostic systems, the sample introduction interface, especially with regards to large volume samples, has often been neglected. We present a sample introduction interface that allows direct o... Read More about Sample introduction interface for on-chip nucleic acid-based analysis of Helicobacter pylori from stool samples.

Magnetic particle plug-based assays for biomarker analysis (2016)
Journal Article
Phurimsak, C., Tarn, M. D., & Pamme, N. (2016). Magnetic particle plug-based assays for biomarker analysis. Micromachines, 7(5), 77. https://doi.org/10.3390/mi7050077

Conventional immunoassays offer selective and quantitative detection of a number of biomarkers, but are laborious and time-consuming. Magnetic particle-based assays allow easy and rapid selection of analytes, but still suffer from the requirement of... Read More about Magnetic particle plug-based assays for biomarker analysis.

Development of radiodetection systems towards miniaturised quality control of PET and SPECT radiopharmaceuticals (2016)
Journal Article
Taggart, M. P., Tarn, M. D., Esfahani, M. M. N., Schofield, D. M., Brown, N. J., Archibald, S. J., …Thompson, L. F. (2016). Development of radiodetection systems towards miniaturised quality control of PET and SPECT radiopharmaceuticals. Lab on a chip, 16(9), 1605-1616. https://doi.org/10.1039/c6lc00099a

The ability to detect radiation in microfluidic devices is important for the on-chip analysis of radiopharmaceuticals, but previously reported systems have largely suffered from various limitations including cost, complexity of fabrication, and insuf... Read More about Development of radiodetection systems towards miniaturised quality control of PET and SPECT radiopharmaceuticals.

Multiplex sorting of foodborne pathogens by on-chip free-flow magnetophoresis (2016)
Journal Article
Ngamsom, B., Esfahani, M. M., Phurimsak, C., Lopez-Martinez, M. J., Raymond, J., Broyer, P., …Pamme, N. (2016). Multiplex sorting of foodborne pathogens by on-chip free-flow magnetophoresis. Analytica Chimica Acta, 918, 69-76. https://doi.org/10.1016/j.aca.2016.03.014

This study reports multiplex sorting of Salmonella typhimurium and Escherichia coli 0157, from broth cultures and from pathogen-spiked skinned chicken breast enrichment broths by employing microfluidic free-flow magnetophoresis. Magnetic beads of dif... Read More about Multiplex sorting of foodborne pathogens by on-chip free-flow magnetophoresis.

Positron detection in silica monoliths for miniaturised quality control of PET radiotracers (2016)
Journal Article
Tarn, M. D., Maneuski, D., Alexander, R., Brown, N. J., O’Shea, V., Pimlott, S. L., …Archibald, S. J. (2016). Positron detection in silica monoliths for miniaturised quality control of PET radiotracers. Chemical communications : Chem comm / the Royal Society of Chemistry, 52(45), 7221-7224. https://doi.org/10.1039/c6cc00660d

We demonstrate the use of the miniaturised Medipix positron sensor for detection of the clinical PET radiotracer, [⁶⁸Ga]gallium-citrate, on a silica-based monolith, towards microfluidic quality control. The system achieved a far superior signal-to-no... Read More about Positron detection in silica monoliths for miniaturised quality control of PET radiotracers.

On-chip acoustophoretic isolation of microflora including S. typhimurium from raw chicken, beef and blood samples (2016)
Journal Article
Ngamsom, B., Lopez-Martinez, M. J., Raymond, J., Broyer, P., Patel, P., & Pamme, N. (2016). On-chip acoustophoretic isolation of microflora including S. typhimurium from raw chicken, beef and blood samples. Journal of microbiological methods, 123, 79-86. https://doi.org/10.1016/j.mimet.2016.01.016

Pathogen analysis in food samples routinely involves lengthy growth-based pre-enrichment and selective enrichment of food matrices to increase the ratio of pathogen to background flora. Similarly, for blood culture analysis, pathogens must be isolate... Read More about On-chip acoustophoretic isolation of microflora including S. typhimurium from raw chicken, beef and blood samples.

Lab-on-a-chip workshop activities for secondary school students (2016)
Journal Article
Esfahani, M. M. N., Tarn, M. D., Choudhury, T. A., Hewitt, L. C., Mayo, A. J., Rubin, T. A., …Pamme, N. (2016). Lab-on-a-chip workshop activities for secondary school students. Biomicrofluidics, 10(1), Article 011301. https://doi.org/10.1063/1.4940884

The ability to engage and inspire younger generations in novel areas of science is important for bringing new researchers into a burgeoning field, such as lab-on-a-chip. We recently held a lab-on-a-chip workshop for secondary school students, for whi... Read More about Lab-on-a-chip workshop activities for secondary school students.

Microfluidically fabricated pH-responsive anionic amphiphilic microgels for drug release (2015)
Journal Article
Lu, B., Tarn, M. D., Pamme, N., & Georgiou, T. K. (2016). Microfluidically fabricated pH-responsive anionic amphiphilic microgels for drug release. Journal of Materials Chemistry B, 4(18), 3086-3093. https://doi.org/10.1039/c5tb02378e

© 2016 The Royal Society of Chemistry. Amphiphilic microgels of different composition based on the hydrophilic, pH-responsive acrylic acid (AA) and the hydrophobic, non-ionic n-butyl acrylate (BuA) were synthesised using a lab-on-a-chip device. Hydro... Read More about Microfluidically fabricated pH-responsive anionic amphiphilic microgels for drug release.

Diamagnetic repulsion of particles for multilaminar flow assays (2015)
Journal Article
Tarn, M. D., Elders, L. T., Peyman, S. A., & Pamme, N. (2015). Diamagnetic repulsion of particles for multilaminar flow assays. RSC advances, 5(126), 103776-103781. https://doi.org/10.1039/c5ra21867e

© The Royal Society of Chemistry. We demonstrate diamagnetic repulsion forces for performing continuous multilaminar flow assays on particles based on their intrinsic properties and with a simple setup. The platform could be applied to sandwich assay... Read More about Diamagnetic repulsion of particles for multilaminar flow assays.

Artificial leaf device for hydrogen generation from immobilised C. reinhardtii microalgae (2015)
Journal Article
Das, A. A. K., Esfahani, M. M. N., Velev, O. D., Pamme, N., & Paunov, V. N. (2015). Artificial leaf device for hydrogen generation from immobilised C. reinhardtii microalgae. Journal of Materials Chemistry A, 3(41), 20698-20707. https://doi.org/10.1039/c5ta07112g

We developed a fully biomimetic leaf-like device for hydrogen production which allows incorporated fabric-immobilised microalgae culture to be simultaneously hydrated with media and harvested from the produced hydrogen in a continuous flow regime wit... Read More about Artificial leaf device for hydrogen generation from immobilised C. reinhardtii microalgae.