All Outputs (80)

Mirtazapine added to SSRIs or SNRIs for treatment resistant depression in primary care: Phase III randomised placebo controlled trial (MIR) (2018)
Journal Article
Kessler, D. S., MacNeill, S. J., Tallon, D., Lewis, G., Peters, T. J., Hollingworth, W., …Wiles, N. J. (2018). Mirtazapine added to SSRIs or SNRIs for treatment resistant depression in primary care: Phase III randomised placebo controlled trial (MIR). BMJ, 363, Article k4218. https://doi.org/10.1136/bmj.k4218

Objective: To investigate the effectiveness of combining mirtazapine with Serotonin-Noradrenaline Reuptake Inhibitor (SNRI) or Selective Serotonin Reuptake Inhibitor (SSRI) antidepressants for patients in primary care who had not responded to an anti... Read More about Mirtazapine added to SSRIs or SNRIs for treatment resistant depression in primary care: Phase III randomised placebo controlled trial (MIR).

Psychometric Properties of the Needs Assessment Tool—Progressive Disease Cancer in U.K. Primary Care (2018)
Journal Article
Allgar, V. L., Chen, H., Richfield, E., Currow, D., Macleod, U., & Johnson, M. J. (2018). Psychometric Properties of the Needs Assessment Tool—Progressive Disease Cancer in U.K. Primary Care. Journal of pain and symptom management, 56(4), 602-612. https://doi.org/10.1016/j.jpainsymman.2018.07.002

Background. The assessment of patients' needs for care is a critical step in achieving patient-centered cancer care. Tools can be used to assess needs and inform care planning. The Needs Assessment Tool:Progressive DiseaseeCancer (NAT:PD-C) is an Aus... Read More about Psychometric Properties of the Needs Assessment Tool—Progressive Disease Cancer in U.K. Primary Care.

Using primary care-based paper and telephone interventions to increase uptake of bowel scope screening in Yorkshire: A protocol of a randomised controlled trial (2018)
Journal Article
McGregor, L. M., Kerrison, R. S., Green, T., MacLeod, U., Hughes, M., Gibbins, M., …Von Wagner, C. (2018). Using primary care-based paper and telephone interventions to increase uptake of bowel scope screening in Yorkshire: A protocol of a randomised controlled trial. BMJ open, 8(7), Article e024616. https://doi.org/10.1136/bmjopen-2018-024616

© Author(s) (or their employer(s)) 2018. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. Introduction Evidence suggests bowel scope screening (BSS) can significantly reduce an individual's risk of... Read More about Using primary care-based paper and telephone interventions to increase uptake of bowel scope screening in Yorkshire: A protocol of a randomised controlled trial.

Emergency admissions and subsequent inpatient care through an emergency oncology service at a tertiary cancer centre: service users’ experiences and views (2018)
Journal Article
Chen, H., Johnson, M., Boland, E., Seymour, J., & Macleod, U. (2019). Emergency admissions and subsequent inpatient care through an emergency oncology service at a tertiary cancer centre: service users’ experiences and views. Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 27(2), 451–460. https://doi.org/10.1007/s00520-018-4328-5

Purpose Avoiding unnecessary emergency admissions and managing those that are admitted more effectively is a major concern for both patients and health services. To generate evidence useful for improving services for direct patient benefit, this stu... Read More about Emergency admissions and subsequent inpatient care through an emergency oncology service at a tertiary cancer centre: service users’ experiences and views.

The diagnostic test accuracy of rectal examination for prostate cancer diagnosis in symptomatic patients: A systematic review (2018)
Journal Article
Jones, D., Friend, C., Dreher, A., Allgar, V., & Macleod, U. (2018). The diagnostic test accuracy of rectal examination for prostate cancer diagnosis in symptomatic patients: A systematic review. BMC family practice, 19(1), Article 79. https://doi.org/10.1186/s12875-018-0765-y

© 2018 The Author(s). Background: Prostate cancer is the most common cancer in men in the UK. NICE guidelines on recognition and referral of suspected cancer, recommend performing digital rectal examination (DRE) on patients with urinary symptoms and... Read More about The diagnostic test accuracy of rectal examination for prostate cancer diagnosis in symptomatic patients: A systematic review.

Use of a GP-endorsed 12 months' reminder letter to promote uptake of bowel scope screening: Protocol for a randomised controlled trial in a hard-to-reach population (2018)
Journal Article
Von Wagner, C., Hirst, Y., Tookey, S., Kerrison, R. S., Marshall, S., Prentice, A., …Duffy, S. (2018). Use of a GP-endorsed 12 months' reminder letter to promote uptake of bowel scope screening: Protocol for a randomised controlled trial in a hard-to-reach population. BMJ open, 8(5), Article e022263. https://doi.org/10.1136/bmjopen-2018-022263

Introduction: Flexible sigmoidoscopy (FS) screening is associated with reduced colorectal cancer incidence and mortality when offered as a one-off test to men and women aged 55-64. The test, also referred to as the 'bowel scope screening' (BSS) test,... Read More about Use of a GP-endorsed 12 months' reminder letter to promote uptake of bowel scope screening: Protocol for a randomised controlled trial in a hard-to-reach population.

Mass media and risk factors for cancer: the under-representation of age (2018)
Journal Article
Macdonald, S., Cunningham, Y., Patterson, C., Robb, K., Macleod, U., Anker, T., & Hilton, S. (2018). Mass media and risk factors for cancer: the under-representation of age. BMC public health, 18(1), Article 490. https://doi.org/10.1186/s12889-018-5341-9

BACKGROUND: Increasing age is a risk factor for developing cancer. Yet, older people commonly underestimate this risk, are less likely to be aware of the early symptoms, and are more likely to be diagnosed with advanced stage cancer. Mass media are a... Read More about Mass media and risk factors for cancer: the under-representation of age.

Myeloma: Patient accounts of their pathways to diagnosis (2018)
Journal Article
Howell, D. A., Hart, R. I., Smith, A. G., Macleod, U., Patmore, R., Cook, G., & Roman, E. (2018). Myeloma: Patient accounts of their pathways to diagnosis. PLoS ONE, 13(4), Article e0194788. https://doi.org/10.1371/journal.pone.0194788

© 2018 Howell et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are cre... Read More about Myeloma: Patient accounts of their pathways to diagnosis.

Self-reported skin concerns: An epidemiological study of community-dwelling older people (2018)
Journal Article
Cowdell, F., Dyson, J., Long, J., & Macleod, U. (2018). Self-reported skin concerns: An epidemiological study of community-dwelling older people. International journal of older people nursing, 13(3), e12195. https://doi.org/10.1111/opn.12195

Background Globally the population is getting older and it is essential to develop effective interventions to promote healthy ageing. Skin change with age is inevitable and renders this often neglected organ more vulnerable to damage and breakdown;... Read More about Self-reported skin concerns: An epidemiological study of community-dwelling older people.

Interventions to improve the uptake of cervical cancer screening among lower socioeconomic groups: A systematic review (2017)
Journal Article
Rees, I., Jones, D., Chen, H., & Macleod, U. (2018). Interventions to improve the uptake of cervical cancer screening among lower socioeconomic groups: A systematic review. Preventive Medicine, 111, 323-335. https://doi.org/10.1016/j.ypmed.2017.11.019

© 2017 Elsevier Inc. Cervical cancer is the fourth most common cancer in women worldwide. Screening can reduce both the incidence and mortality of the disease but is often not utilized by lower socioeconomic groups. A systematic review, including stu... Read More about Interventions to improve the uptake of cervical cancer screening among lower socioeconomic groups: A systematic review.

Experience of, awareness of and help-seeking for potential cancer symptoms in smokers and non-smokers: a cross-sectional study (2017)
Journal Article
Walabyeki, J., Adamson, J., Buckley, H. L., Sinclair, H., Atkin, K., Graham, H., …Macleod, U. (2017). Experience of, awareness of and help-seeking for potential cancer symptoms in smokers and non-smokers: a cross-sectional study. PLoS ONE, 12(8), e0183647. https://doi.org/10.1371/journal.pone.0183647

Background Presenting to primary care with potential cancer symptoms is contingent on one’s ability to recognize potentially serious symptoms. We investigated differences between smokers and non-smokers in symptoms experienced, awareness and consulti... Read More about Experience of, awareness of and help-seeking for potential cancer symptoms in smokers and non-smokers: a cross-sectional study.

The complex relationship between household income of family caregivers, access to palliative care services and place of death: A national household population survey (2017)
Journal Article
Chen, H., Currow, D. C., Dunn, L., Johnson, M. J., Macleod, U., & Allgar, V. (2018). The complex relationship between household income of family caregivers, access to palliative care services and place of death: A national household population survey. Palliative medicine, 32(2), 357-365. https://doi.org/10.1177/0269216317711825

Background: Previous work shows that more affluent patients with cancer are more likely to die at home, whereas those dying from non-cancer conditions are more likely to die in hospital. Family caregivers are an important factor in determining place... Read More about The complex relationship between household income of family caregivers, access to palliative care services and place of death: A national household population survey.

Attitudes of newly qualified doctors towards a career in general practice: A qualitative focus group study (2017)
Journal Article
Merrett, A., Jones, D., Sein, K., Green, T., & Macleod, U. (2017). Attitudes of newly qualified doctors towards a career in general practice: A qualitative focus group study. The British journal of general practice : the journal of the Royal College of General Practitioners, 67(657), e253-e259. https://doi.org/10.3399/bjgp17X690221

© British Journal of General Practice 2017. Background A key element of the NHS is universal access to a GP. Recently, UK general practice has been described as being in crisis, with training places unfilled and multiple practices reporting vacancies... Read More about Attitudes of newly qualified doctors towards a career in general practice: A qualitative focus group study.

Multiple myeloma: routes to diagnosis, clinical characteristics and survival - findings from a UK population-based study (2017)
Journal Article
Howell, D., Smith, A., Appleton, S., Bagguley, T., Macleod, U., Cook, G., …Roman, E. (2017). Multiple myeloma: routes to diagnosis, clinical characteristics and survival - findings from a UK population-based study. British journal of haematology, 177(1), 67-71. https://doi.org/10.1111/bjh.14513

Prompt cancer diagnosis may align UK survival with European averages. We examined the impact of route to diagnosis on survival for multiple myeloma patients diagnosed 2012–2013 using data from our population-based patient cohort that links to nationa... Read More about Multiple myeloma: routes to diagnosis, clinical characteristics and survival - findings from a UK population-based study.

Do colorectal cancer patients diagnosed as an emergency differ from non-emergency patients in their consultation patterns and symptoms? A longitudinal data-linkage study in England (2016)
Journal Article
Renzi, C., Lyratzopoulos, G., Card, T., Chu, T., Macleod, U., & Rachet, B. (2016). Do colorectal cancer patients diagnosed as an emergency differ from non-emergency patients in their consultation patterns and symptoms? A longitudinal data-linkage study in England. The British Journal of Cancer, 115(7), 866-875. https://doi.org/10.1038/bjc.2016.250

Background: More than 20% of colorectal cancers are diagnosed following an emergency presentation. We aimed to examine pre-diagnostic primary-care consultations and related symptoms comparing patients diagnosed as emergencies with those diagnosed thr... Read More about Do colorectal cancer patients diagnosed as an emergency differ from non-emergency patients in their consultation patterns and symptoms? A longitudinal data-linkage study in England.

Illness identity as an important component of candidacy: Contrasting experiences of help-seeking and access to care in cancer and heart disease (2016)
Journal Article
Macleod, U., Blane, D., Browne, S., Conway, E., Macdonald, S., Mair, F., & May, C. (2016). Illness identity as an important component of candidacy: Contrasting experiences of help-seeking and access to care in cancer and heart disease. Social science & medicine, 168, 101-110. https://doi.org/10.1016/j.socscimed.2016.08.022

How and when we use health services or healthcare provision has dominated exploration of and debates around healthcare access. Levels of utilisation are assumed as a proxy for access. Yet, focusing on utilisation conceals an important aspect of the a... Read More about Illness identity as an important component of candidacy: Contrasting experiences of help-seeking and access to care in cancer and heart disease.

The adaptation, face, and content validation of a needs assessment tool: progressive disease for people with interstitial lung disease (2016)
Journal Article
Boland, J. W., Reigada, C., Yorke, J., Hart, S. P., Bajwah, S., Ross, J., …Johnson, M. J. (2016). The adaptation, face, and content validation of a needs assessment tool: progressive disease for people with interstitial lung disease. Journal of palliative medicine, 19(5), 549-555. https://doi.org/10.1089/jpm.2015.0355

Background: Irrreversible interstitial lung disease (ILD) is associated with high morbidity and mortality. Palliative care needs of patients and caregivers are not routinely assessed; there is no tool to identify needs and triage support in clinical... Read More about The adaptation, face, and content validation of a needs assessment tool: progressive disease for people with interstitial lung disease.

Mirtazapine added to selective serotonin reuptake inhibitors for treatment-resistant depression in primary care (MIR trial): Study protocol for a randomised controlled trial (2016)
Journal Article
Tallon, D., Wiles, N., Campbell, J., Chew-Graham, C., Dickens, C., Macleod, U., …Kessler, D. (2016). Mirtazapine added to selective serotonin reuptake inhibitors for treatment-resistant depression in primary care (MIR trial): Study protocol for a randomised controlled trial. Trials, 17(1), Article 66. https://doi.org/10.1186/s13063-016-1199-2

© 2016 Tallon et al. Background: People with depression are usually managed in primary care and antidepressants are often the first-line treatment, but only one third of patients respond fully to a single antidepressant. This paper describes the prot... Read More about Mirtazapine added to selective serotonin reuptake inhibitors for treatment-resistant depression in primary care (MIR trial): Study protocol for a randomised controlled trial.

Family caregivers who would be unwilling to provide care at the end of life again: findings from the Health Survey for England population survey (2016)
Journal Article
Johnson, M. J., Allgar, V., Macleod, U., Jones, A., Oliver, S., & Currow, D. (2016). Family caregivers who would be unwilling to provide care at the end of life again: findings from the Health Survey for England population survey. PLoS ONE, 11(1), e0146960. https://doi.org/10.1371/journal.pone.0146960

Background Family caregivers provide significant care at the end of life. We aimed to describe caregiver characteristics, and of those unwilling to repeat this role under the same circumstances. Methods Observational study of adults in private househ... Read More about Family caregivers who would be unwilling to provide care at the end of life again: findings from the Health Survey for England population survey.

Does the use of specialist palliative care services modify the effect of socioeconomic status on place of death? A systematic review (2015)
Journal Article
Chen, H., Nicolson, D. J., MacLeod, U., Allgar, V., Dalgliesh, C., & Johnson, M. (2016). Does the use of specialist palliative care services modify the effect of socioeconomic status on place of death? A systematic review. Palliative medicine, 30(5), 434-445. https://doi.org/10.1177/0269216315602590

© SAGE Publications. Background: Cancer patients in lower socioeconomic groups are significantly less likely to die at home and experience more barriers to access to palliative care. It is unclear whether receiving palliative care may mediate the eff... Read More about Does the use of specialist palliative care services modify the effect of socioeconomic status on place of death? A systematic review.