Polymorphisms in LMNA and near a SERPINA gene cluster are associated with cognitive function in older people
(2010)
Journal Article
Cluett, C., Brayne, C., Clarke, R., Evans, G., Matthews, F., Rubinsztein, D. C., …Melzer, D. (2010). Polymorphisms in LMNA and near a SERPINA gene cluster are associated with cognitive function in older people. Neurobiology of Aging, 31(9), 1563-1568. https://doi.org/10.1016/j.neurobiolaging.2008.08.020
A recent genome-wide association (GWA) study of late-onset Alzheimer's disease (LOAD) identified 15 novel single nucleotide polymorphisms (SNPs) independent of ApoE. We hypothesised that variants associated with LOAD are also associated with poor cog... Read More about Polymorphisms in LMNA and near a SERPINA gene cluster are associated with cognitive function in older people.