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All Outputs (57)

High-intensity interval training in patients with intermittent claudication (2023)
Presentation / Conference Contribution
Pymer, S., Harwood, A. E., Prosser, J., Waddell, A., Rhavindhran, B., McGregor, G., Ibeggazene, S., Huang, C., Twiddy, M., Nicholls, A. R., Ingle, L., Carroll, S., He, H., Long, J., Rooms, M., & Chetter, I. C. High-intensity interval training in patients with intermittent claudication. Presented at 2022 Vascular Society of Great Britain and Ireland Annual Scientific Meeting, Brighton, UK

Objective: Provision, uptake, adherence, and completion rates for supervised exercise programs (SEP) for intermittent claudication (IC) are low. A shorter, more time-efficient, 6-week, high-intensity interval training (HIIT) program may be an effecti... Read More about High-intensity interval training in patients with intermittent claudication.

A preoperative supervised exercise program potentially improves long-term survival after elective abdominal aortic aneurysm repair (2023)
Presentation / Conference Contribution
Sethi, S., Ravindhran, B., Long, J., Gurung, R., Huang, C., Smith, G. E., Carradice, D., Wallace, T., Ibeggazene, S., Chetter, I. C., & Pymer, S. A preoperative supervised exercise program potentially improves long-term survival after elective abdominal aortic aneurysm repair. Presented at 2023 Vascular Annual Meeting of the Society for Vascular Surgery, National Harbor, Maryland

Objective: A preoperative supervised exercise program (SEP) improves cardiorespiratory fitness and perioperative outcomes for patients undergoing elective abdominal aortic aneurysm (AAA) repair. The aim of this study was to assess the effect of a pre... Read More about A preoperative supervised exercise program potentially improves long-term survival after elective abdominal aortic aneurysm repair.

Abstract B001: Calcitonin receptor-like receptor agonists induce p44/42 MAPK phosphorylation in VEGF-A-stimulated human blood endothelial cells after bevacizumab treatment (2023)
Presentation / Conference Contribution
Morfitt, M. A., Greenman, J., Maraveyas, A., & Nikitenko, L. L. Abstract B001: Calcitonin receptor-like receptor agonists induce p44/42 MAPK phosphorylation in VEGF-A-stimulated human blood endothelial cells after bevacizumab treatment. Presented at AACR Special Conference: Advances in Kidney Cancer Research, Austin, Texas, U.S.A

Introduction. Clear cell renal cell carcinoma (ccRCC) is a highly vascularized and clinically aggressive cancer. In the UK, there are around 9000 diagnoses and 3000 deaths annually. Targeted therapies that inhibit angiogenic regulators, such as bevac... Read More about Abstract B001: Calcitonin receptor-like receptor agonists induce p44/42 MAPK phosphorylation in VEGF-A-stimulated human blood endothelial cells after bevacizumab treatment.

Abstract A020: Calcitonin receptor-like receptor is expressed in blood vessels in clear cell renal cell carcinoma and upregulated in endothelial cells co-cultured with tumor cells (2023)
Presentation / Conference Contribution
Morfitt, M. A., Greenman, J., Maraveyas, A., Harris, A. L., & Nikitenko, L. L. Abstract A020: Calcitonin receptor-like receptor is expressed in blood vessels in clear cell renal cell carcinoma and upregulated in endothelial cells co-cultured with tumor cells. Presented at AACR Special Conference on Advances in Kidney Cancer Research, Austin, Texas, U.S.A

Introduction. Clear cell renal cell carcinoma (ccRCC) is a highly vascularized and clinically aggressive kidney cancer, with high rates of metastasis and recurrence after cytoreductive nephrectomy. ccRCC can be treated with anti-angiogenic drugs, how... Read More about Abstract A020: Calcitonin receptor-like receptor is expressed in blood vessels in clear cell renal cell carcinoma and upregulated in endothelial cells co-cultured with tumor cells.

Quantitative proteomics of pancreatic cyst fluid for early diagnosis of cancer. (2023)
Presentation / Conference Contribution
Nikitenko, L. L., Manolis, D., O'Brien, D. P., Adekeye, A., Kessler, B. M., Collins, C., Kramer, H., Chang, D., & Maraveyas, A. Quantitative proteomics of pancreatic cyst fluid for early diagnosis of cancer. Presented at The London Pancreas Workshop 2023, London, United Kingdom

In our EARLY DIAgnosis of PAncreatic Cancer (EARLY DIAPAC) study, we aim to analyse molecular changes or “signatures” associated with early stages of pancreatic carcinogenesis by using the combination of: (i) Label-Free Quantitative Proteomics (LFQP)... Read More about Quantitative proteomics of pancreatic cyst fluid for early diagnosis of cancer..

Abstract 224: Establishing de novo platform for whole genome sequencing of pancreatic cyst fluid for early detection and diagnosis of pancreatic cancer (2023)
Presentation / Conference Contribution
Adekeye, A., Haque, F., Ettelaie, C., Nikitenko, L., & Maraveyas, A. Abstract 224: Establishing de novo platform for whole genome sequencing of pancreatic cyst fluid for early detection and diagnosis of pancreatic cancer. Presented at AACR Annual Meeting 2023, Orlando, Florida

Background: Pancreatic cancer (PC) is a leading cause of cancer-related deaths globally. Accurate PC detection at early or premalignant stage, when surgery is effective, would increase survival rates and prevent unnecessary surgery or surveillance. A... Read More about Abstract 224: Establishing de novo platform for whole genome sequencing of pancreatic cyst fluid for early detection and diagnosis of pancreatic cancer.

Do we need routine antibiotics for hand surgery? (2022)
Presentation / Conference Contribution
Wormald, J., & Totty, J. (2022, October). Do we need routine antibiotics for hand surgery?. Paper presented at British Society for Surgery of the Hand (BSSH) Autumn Scientific Meeting 2022, Winchester, UK

Both the incidence of hand trauma, and the demand for elective hand surgery, continue to rise in the UK. The incidence of surgical site infection (SSI) following hand surgery is around 5%. Traditionally, antibiotic prophylaxis at the time of surgery... Read More about Do we need routine antibiotics for hand surgery?.

A Mixed Methods Feasibility Study of Extracorporeal Shockwave Therapy for Diabetic Foot Ulcers (2021)
Presentation / Conference Contribution
Hitchman, L., Totty, J., Lathan, R., Sidapra, M., Smith, G., Carradice, D., & Chetter, I. A Mixed Methods Feasibility Study of Extracorporeal Shockwave Therapy for Diabetic Foot Ulcers

Aim
The purpose of this mixed methods feasibility study was to assess the feasibility of delivering ESWT to patients with DFUs. It also aimed to explore any potential clinical effect of ESWT on wound healing and investigate whether ESWT may offer an... Read More about A Mixed Methods Feasibility Study of Extracorporeal Shockwave Therapy for Diabetic Foot Ulcers.

Photograph-based telemedicine: a promising tool for postoperative wound assessment in the diagnosis or exclusion of surgical site infection (2018)
Presentation / Conference Contribution
Totty, J. P., Harwood, A. E., Wallace, T., Smith, G. E., & Chetter, I. C. (2018, May). Photograph-based telemedicine: a promising tool for postoperative wound assessment in the diagnosis or exclusion of surgical site infection. Paper presented at EWMA 2018 Krakow: New frontiers in wound management, Krakow Poland

Long-term outcomes of a randomized clinical trial of supervised exercise, percutaneous transluminal angioplasty or combined treatment for patients with intermittent claudication due to femoropopliteal disease (2017)
Presentation / Conference Contribution
Mazari, F. A., Khan, J. A., Samuel, N., Smith, G., Carradice, D., McCollum, P., & Chetter, I. Long-term outcomes of a randomized clinical trial of supervised exercise, percutaneous transluminal angioplasty or combined treatment for patients with intermittent claudication due to femoropopliteal disease

Background: To compare the long-term outcomes of angioplasty (PTA), supervised exercise (SEP) and combined treatment (PTA+SEP) in patients with intermittent claudication (IC) due to femoropopliteal disease. Methods: Patients recruited to PTA, SEP and... Read More about Long-term outcomes of a randomized clinical trial of supervised exercise, percutaneous transluminal angioplasty or combined treatment for patients with intermittent claudication due to femoropopliteal disease.

Prospective observational study for comparison of use of Short Form-36 dimension scores and patient responses for derivation of preference based Short Form-6D index to calculate of quality adjusted life years (QALYs) for economic analyses in patients with (2010)
Presentation / Conference Contribution
Mazari, F., Abdul Rahman, H., Khan, J., Mockford, K., McCollum, P., & Chetter, I. Prospective observational study for comparison of use of Short Form-36 dimension scores and patient responses for derivation of preference based Short Form-6D index to calculate of quality adjusted life years (QALYs) for economic analyses in patients with

Cost utility analysis of a randomised control trial of percutaneous transluminal angioplasty (PTA), supervised exercise programme (SEP) and combined treatment (PTA plus SEP) for patients with intermittent claudication (IC) due to femoropopliteal disease (2010)
Presentation / Conference Contribution
Mazari, F., Abdul Rahman, H., Khan, J., McCollum, P., Gulati, S., Mehta, T., & Chetter, I. Cost utility analysis of a randomised control trial of percutaneous transluminal angioplasty (PTA), supervised exercise programme (SEP) and combined treatment (PTA plus SEP) for patients with intermittent claudication (IC) due to femoropopliteal disease