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All Outputs (17)

Paper microfluidic sensors towards on-site environmental analysis of soil nutrients (2024)
Thesis
Al Hinai, S. Paper microfluidic sensors towards on-site environmental analysis of soil nutrients. (Thesis). University of Hull. https://hull-repository.worktribe.com/output/4617797

The increase in the world population leads to an increase in the need for production of crops. To optimise crop production fertilizer application needs to be managed by the farmer, consequently, regular information about the chemistry of the soil is... Read More about Paper microfluidic sensors towards on-site environmental analysis of soil nutrients.

Novel Synthesis Methods For the Production of Human Circulating Metabolites of Natural Products (2024)
Thesis
Doyle, B. Novel Synthesis Methods For the Production of Human Circulating Metabolites of Natural Products. (Thesis). University of Hull. https://hull-repository.worktribe.com/output/4587910

Upon entering the body, any given xenobiotic can undergo metabolism which facilitates its excretion from the body. When metabolised, a compound typically has the same effects of the initial drug/nutraceutical, however this is not always the case and... Read More about Novel Synthesis Methods For the Production of Human Circulating Metabolites of Natural Products.

Development of analytical workflows for measurement of metal pollution in freshwater with citizen scientists (2023)
Thesis
Sari, M. Development of analytical workflows for measurement of metal pollution in freshwater with citizen scientists. (Thesis). University of Hull. https://hull-repository.worktribe.com/output/4459145

The emergence of heavy metals, such as nickel (Ni2+) and zinc (Zn2+), as freshwater contaminant poses an environmental and public health risk. However, the current monitoring process lacks robustness and the spatiotemporal range, impeded by relativel... Read More about Development of analytical workflows for measurement of metal pollution in freshwater with citizen scientists.

Development of a skin-on-a-chip platform for the study of wound healing (2022)
Thesis
Talar, K. Development of a skin-on-a-chip platform for the study of wound healing. (Thesis). University of Hull. https://hull-repository.worktribe.com/output/4508234

Wound healing abnormalities and non-healing chronic wounds are a major clinical problem, primarily affecting diabetic and elderly patients. Wound management associated costs resulted in a £5.3 billion financial burden to the NHS between 2012 and 2013... Read More about Development of a skin-on-a-chip platform for the study of wound healing.

Microcapsule synthesis for 3D printing of self-healing materials (2021)
Thesis
Sanders, P. Microcapsule synthesis for 3D printing of self-healing materials. (Thesis). University of Hull. https://hull-repository.worktribe.com/output/4223143

3D printing allows for the manufacture of finished structures from starting components with essentially no specialist training required. The process is autonomous; the starting components, such as inks, are poured into the machine and the finished pr... Read More about Microcapsule synthesis for 3D printing of self-healing materials.

Focusing and delivery of laser radiation for nano- and microfabrication (2020)
Thesis
Al-Jarwany, Q. A. Focusing and delivery of laser radiation for nano- and microfabrication. (Thesis). University of Hull. https://hull-repository.worktribe.com/output/4223093

The recent advances in nanotechnology and nanofabrication motivate the drive to achieve a tighter focusing of light; this requires a high numerical aperture (NA) optical system. The need for high optical resolution has led scientists to discover the... Read More about Focusing and delivery of laser radiation for nano- and microfabrication.

The use of precision cut lung slices and co-culture modelling to investigate the effect of human rhinovirus on cough and airway inflammation (2020)
Thesis
Stinson, R. J. The use of precision cut lung slices and co-culture modelling to investigate the effect of human rhinovirus on cough and airway inflammation. (Thesis). Hull York Medical School, the University of Hull and the University of York. https://hull-repository.worktribe.com/output/4222863

Human Rhinovirus (hRV) is a major cause of upper respiratory tract infections (URTIs) and is linked to lower respiratory tract infections (LRTIs) and airway diseases exacerbations. Cough, airway inflammation and hypersensation are common symptoms of... Read More about The use of precision cut lung slices and co-culture modelling to investigate the effect of human rhinovirus on cough and airway inflammation.

An optical label-free aptasensor based on dye doped leaky waveguide (DDLW) for biomarker detection (2019)
Thesis
Alamrani, N. A. An optical label-free aptasensor based on dye doped leaky waveguide (DDLW) for biomarker detection. (Thesis). University of Hull. https://hull-repository.worktribe.com/output/4749483

Due to the rapid increase in routine measurement of biomarkers, such as a protein, in blood samples for healthcare monitoring, different techniques have been developed to facilitate this measurement in terms of cost-effective and fast measurement. La... Read More about An optical label-free aptasensor based on dye doped leaky waveguide (DDLW) for biomarker detection.

Developing a novel spheroid-on-chip microfluidic device for investigations into metastasis (2019)
Thesis
Collins, T. C. Developing a novel spheroid-on-chip microfluidic device for investigations into metastasis. (Thesis). University of Hull. https://hull-repository.worktribe.com/output/4221851

One in two people born after 1960 will develop cancer, with 90% of all cancer deaths arising from metastasis. Conventional 2D in vitro metastasis models do not fully replicate tumour complexity. In vivo models can address tumour complexity, but do no... Read More about Developing a novel spheroid-on-chip microfluidic device for investigations into metastasis.

Optical sensor for the analysis of biomarkers (2018)
Thesis
Al-Shemary, R. S. Optical sensor for the analysis of biomarkers. (Thesis). University of Hull. https://hull-repository.worktribe.com/output/4220996

The continuous measurement of biomarkers such as proteins and hormones in blood and serum are the cornerstone of healthcare monitoring and optimising treatment plans. Often such biomarkers are present in minute concentrations. Conventional analysis m... Read More about Optical sensor for the analysis of biomarkers.

Nanogap capacitive biosensor for label-free aptamer-based protein detection (2018)
Thesis
Namhil, Z. G. Nanogap capacitive biosensor for label-free aptamer-based protein detection. (Thesis). University of Hull. https://hull-repository.worktribe.com/output/4220514

Recent advances in nanotechnology offer a new platform for the label free detection of biomolecules at ultra-low concentrations. Nano biosensors are emerging as a powerful method of improving device performance whilst minimizing device size, cost and... Read More about Nanogap capacitive biosensor for label-free aptamer-based protein detection.

Surface enhanced Raman spectroscopy for single molecule detection and biosensing (2017)
Thesis
Marshall, A. R. L. Surface enhanced Raman spectroscopy for single molecule detection and biosensing. (Thesis). University of Hull. https://hull-repository.worktribe.com/output/4220864

The aim of this thesis is to design plasmonic nano-gaps capable of detecting materials down to sufficiently low concentrations such that single molecule characteristics are observed. We begin first, by discussing the theory of plasmonics. Then, we as... Read More about Surface enhanced Raman spectroscopy for single molecule detection and biosensing.

Microparticle image processing and field profile optimisation for automated Lab-On-Chip magnetophoretic analytical systems (2016)
Thesis
Chowdhury, M. M. U. Microparticle image processing and field profile optimisation for automated Lab-On-Chip magnetophoretic analytical systems. (Thesis). University of Hull. https://hull-repository.worktribe.com/output/4219336

The work described in this thesis, concerns developments to analytical microfluidic Lab-On-Chip platform originally developed by Prof Pamme's research group at the University of Hull. This work aims to move away from traditional laboratory analysis s... Read More about Microparticle image processing and field profile optimisation for automated Lab-On-Chip magnetophoretic analytical systems.

Development of a combined DNA and drug extraction methodology for forensic toxicology application (2014)
Thesis
Kashkary, L. M. T. Development of a combined DNA and drug extraction methodology for forensic toxicology application. (Thesis). University of Hull. https://hull-repository.worktribe.com/output/4217177

Biological samples recovered at crime scenes may contain unsuspected and valuable evidence, such as illicit drugs, in addition to nucleic acids. Deoxyribonucleic acid (DNA) analysis provides valuable information to identify a suspect or victim, as we... Read More about Development of a combined DNA and drug extraction methodology for forensic toxicology application.

Development of a microfluidic device for the in situ production of singlet oxygen for chemical and biological applications (2012)
Thesis
Lumley, E. K. Development of a microfluidic device for the in situ production of singlet oxygen for chemical and biological applications. (Thesis). University of Hull. https://hull-repository.worktribe.com/output/4219891

Cancer cells are derived from cells that are termed, and recognised as being 'self', meaning that the immune system does not target them. Many treatments target the tumour through its requirement for large quantities of nutrients. However, this cause... Read More about Development of a microfluidic device for the in situ production of singlet oxygen for chemical and biological applications.

Magnetic forces for surface-based bioanalysis in microfluidic devices (2010)
Thesis
Peyman, S. A. Magnetic forces for surface-based bioanalysis in microfluidic devices. (Thesis). University of Hull. https://hull-repository.worktribe.com/output/4213006

Biochemical analysis is a critical part of clinical diagnostics, forensic science and environmental monitoring. Typically, this form of analysis involves the use of bioanalytical procedures which are extremely sensitive and highly specific. However,... Read More about Magnetic forces for surface-based bioanalysis in microfluidic devices.