All Outputs (4)

Characterisation of a RhoBTB3 deficient mouse model (2012)
Thesis
Lutz, J. B. (2012). Characterisation of a RhoBTB3 deficient mouse model. (Thesis). Hull York Medical School, the University of Hull and the University of York. Retrieved from https://hull-repository.worktribe.com/output/4219075

RhoBTB proteins are atypical members of the Rho-family of small GTPases with a characteristic domain architecture: a GTPase-domain is followed by a proline-rich region, a tandem of two BTB domains and a C-terminal region. RhoBTB3 is the most divergen... Read More about Characterisation of a RhoBTB3 deficient mouse model.

MUF1/leucine-rich repeat containing 41 (LRRC41), a substrate of RhoBTB-dependent cullin 3 ubiquitin ligase complexes, is a predominantly nuclear dimeric protein (2012)
Journal Article
Schenková, K., Lutz, J., Kopp, M., Ramos, S., & Rivero, F. (2012). MUF1/leucine-rich repeat containing 41 (LRRC41), a substrate of RhoBTB-dependent cullin 3 ubiquitin ligase complexes, is a predominantly nuclear dimeric protein. Journal of Molecular Biology, 422(5), 659-673. https://doi.org/10.1016/j.jmb.2012.06.016

RhoBTB (BTB stands for broad-complex, tramtrack, bric à brac) proteins are tumor suppressors involved in the formation of cullin 3 (Cul3)-dependent ubiquitin ligase complexes. However, no substrates of RhoBTB-Cul3 ubiquitin ligase complexes have been... Read More about MUF1/leucine-rich repeat containing 41 (LRRC41), a substrate of RhoBTB-dependent cullin 3 ubiquitin ligase complexes, is a predominantly nuclear dimeric protein.

The Rac GEF ZizB regulates development, cell motility and cytokinesis in Dictyostelium (2012)
Journal Article
Pakes, N. K., Veltman, D. M., Rivero, F., Nasir, J., Insall, R., & Williams, R. S. (2012). The Rac GEF ZizB regulates development, cell motility and cytokinesis in Dictyostelium. Journal of cell science, 125(10), 2457-2465. https://doi.org/10.1242/jcs.100966

Dock (dedicator of cytokinesis) proteins represent a family of guanine nucleotide exchange factors (GEFs) that include the well-studied Dock180 family and the poorly characterised zizimin family. Our current understanding of Dock180 function is that... Read More about The Rac GEF ZizB regulates development, cell motility and cytokinesis in Dictyostelium.

Ectopic expression of cyclase associated protein CAP restores the streaming and aggregation defects of adenylyl cyclase a deficient Dictyostelium discoideum cells (2012)
Journal Article
Sultana, H., Neelakanta, G., Rivero, F., Blau-Wasser, R., Schleicher, M., & Noegel, A. A. (2012). Ectopic expression of cyclase associated protein CAP restores the streaming and aggregation defects of adenylyl cyclase a deficient Dictyostelium discoideum cells. BMC developmental biology, 12, Article 3. https://doi.org/10.1186/1471-213X-12-3

Background: Cell adhesion, an integral part of D. discoideum development, is important for morphogenesis and regulated gene expression in the multicellular context and is required to trigger cell-differentiation. G-protein linked adenylyl cyclase pat... Read More about Ectopic expression of cyclase associated protein CAP restores the streaming and aggregation defects of adenylyl cyclase a deficient Dictyostelium discoideum cells.