All Outputs (5)

Exploring quality of life in patients with and without heart failure (2015)
Journal Article
Zhang, J., Hobkirk, J., Carroll, S., Pellicori, P., Clark, A. L., & Cleland, J. G. (2016). Exploring quality of life in patients with and without heart failure. International journal of cardiology, 202, 676-684. https://doi.org/10.1016/j.ijcard.2015.09.076

Aims The EuroHeart Failure Survey Questionnaire (EHFSQ-1) has 39 questions on symptoms and quality of life (QoL); many items are related. We sought to identify underlying clusters amongst EHFSQ-1 questions, construct an overall “QoL score” and invest... Read More about Exploring quality of life in patients with and without heart failure.

Development of a human model for the study of effects of hypoxia, exercise, and sildenafil on cardiac and vascular function in chronic heart failure (2015)
Journal Article
Damy, T., Hobkirk, J., Walters, M., Ciobanu, A., Rigby, A. S., Kallvikbacka-Bennett, A., …Cleland, J. G. F. (2015). Development of a human model for the study of effects of hypoxia, exercise, and sildenafil on cardiac and vascular function in chronic heart failure. Journal of Cardiovascular Pharmacology, 66(3), 229-238. https://doi.org/10.1097/fjc.0000000000000262

Background: Pulmonary hypertension is associated with poor outcome in patients with chronic heart failure (CHF) and may be a therapeutic target. Our aims were to develop a noninvasive model for studying pulmonary vasoreactivity in CHF and characteriz... Read More about Development of a human model for the study of effects of hypoxia, exercise, and sildenafil on cardiac and vascular function in chronic heart failure.

Does home oxygen therapy (HOT) in addition to standard care reduce disease severity and improve symptoms in people with chronic heart failure? A randomised trial of home oxygen therapy for patients with chronic heart failure (2015)
Journal Article
Clark, A. L., Johnson, M., Fairhurst, C., Torgerson, D., Cockayne, S., Rodgers, S., …Greenstone, M. (2015). Does home oxygen therapy (HOT) in addition to standard care reduce disease severity and improve symptoms in people with chronic heart failure? A randomised trial of home oxygen therapy for patients with chronic heart failure. Health Technology Assessment, 19(75), 1-120. https://doi.org/10.3310/hta19750

Background: Home oxygen therapy (HOT) is commonly used for patients with severe chronic heart failure (CHF) who have intractable breathlessness. There is no trial evidence to support its use. Objectives: To detect whether or not there was a quality-... Read More about Does home oxygen therapy (HOT) in addition to standard care reduce disease severity and improve symptoms in people with chronic heart failure? A randomised trial of home oxygen therapy for patients with chronic heart failure.

The obesity paradox in Type 2 Diabetes Mellitus: Relationship of Body Mass Index to Prognosis: A Cohort Study (2015)
Journal Article
Costanzo, P., Cleland, J. G., Pellicori, P., Clark, A. L., Hepburn, D., Kilpatrick, E. S., …Atkin, S. L. (2015). The obesity paradox in Type 2 Diabetes Mellitus: Relationship of Body Mass Index to Prognosis: A Cohort Study. Annals of Internal Medicine, 162(9), 610. https://doi.org/10.7326/m14-1551

Background: Whether obesity is associated with a better prognosis in patients with type 2 diabetes mellitus is controversial. Objective: To investigate the association between body weight and prognosis in a large cohort of patients with type 2 d... Read More about The obesity paradox in Type 2 Diabetes Mellitus: Relationship of Body Mass Index to Prognosis: A Cohort Study.

Prescribing patterns to optimize heart rate (2015)
Journal Article
Dierckx, R., Cleland, J. G., Parsons, S., Putzu, P., Pellicori, P., Dicken, B., …Clark, A. L. (2015). Prescribing patterns to optimize heart rate. JACC: Heart Failure, 3(3), 224-230. https://doi.org/10.1016/j.jchf.2014.11.003

Objectives This study sought to characterize patients attending a community heart failure (HF) clinic and identified those who were eligible for optimization of beta-blockers (BB) or ivabradine. Background Among patients with HF due to left vent... Read More about Prescribing patterns to optimize heart rate.