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Cerebral Regulation in Different Maximal Aerobic Exercise Modes (2016)
Journal Article
Pires, F. O., dos Anjos, C. A. S., Covolan, R. J. M., Pinheiro, F. A., St Clair Gibson, A., Noakes, T. D., …Ugrinowitsch, C. (in press). Cerebral Regulation in Different Maximal Aerobic Exercise Modes. Frontiers in Physiology, 7, Article 253. https://doi.org/10.3389/fphys.2016.00253

We investigated cerebral responses, simultaneously with peripheral and ratings of perceived exertion (RPE) responses, during different VO2MAX-matched aerobic exercise modes. Nine cyclists (VO2MAX of 57.5 ± 6.2 ml·kg−1·min−1) performed a maximal, cont... Read More about Cerebral Regulation in Different Maximal Aerobic Exercise Modes.

Prevalence and outcomes of anemia and hematinic deficiencies in patients with chronic heart failure (2016)
Journal Article
Cleland, J. G., Zhang, J., Pellicori, P., Dicken, B., Dierckx, R., Shoaib, A., …Clark, A. L. (2016). Prevalence and outcomes of anemia and hematinic deficiencies in patients with chronic heart failure. JAMA Cardiology, 1(5), 539-547. https://doi.org/10.1001/jamacardio.2016.1161

Copyright © 2016 American Medical Association. All rights reserved. Importance: Detailed information on the prevalence, associations, and consequences of anemia and iron deficiency in epidemiologically representative outpatients with chronic heart fa... Read More about Prevalence and outcomes of anemia and hematinic deficiencies in patients with chronic heart failure.

A thematic synthesis of the experiences of adults living with hemodialysis (2016)
Journal Article
Reid, C., Seymour, J., & Jones, C. (2016). A thematic synthesis of the experiences of adults living with hemodialysis. Clinical journal of the American Society of Nephrology, 11(7), 1206-1218. https://doi.org/10.2215/CJN.10561015

Background and objectives In-center dialysis patients spend significant amounts of time on the dialysis unit; additionally managing ESKD affects many aspects of life outside the dialysis unit. To improve the care provided to patients requiring hemodi... Read More about A thematic synthesis of the experiences of adults living with hemodialysis.

Relationship between methylation status of Vitamin D-related genes, Vitamin D levels, and methyl-donor biochemistry (2016)
Journal Article
Beckett, E., Duesing, K., Martin, C., Jones, P., Furst, J., King, K., …Lucock, M. (2016). Relationship between methylation status of Vitamin D-related genes, Vitamin D levels, and methyl-donor biochemistry. Journal of Nutrition and Intermediary Metabolism, 6, 8-15. https://doi.org/10.1016/j.jnim.2016.04.010

© 2016 The Authors. Published by Elsevier Inc. Vitamin D is known for its role in the regulation of gene expression via the Vitamin D receptor, a nuclear transcription factor. More recently, a role for Vitamin D in regulating DNA methylation has been... Read More about Relationship between methylation status of Vitamin D-related genes, Vitamin D levels, and methyl-donor biochemistry.

A Systematic Review of the Uptake and Adherence Rates to Supervised Exercise Programs in Patients with Intermittent Claudication (2016)
Journal Article
Harwood, A., Smith, G. E., Cayton, T., Broadbent, E., & Chetter, I. C. (2016). A Systematic Review of the Uptake and Adherence Rates to Supervised Exercise Programs in Patients with Intermittent Claudication. Annals of vascular surgery, 34, 280-289. https://doi.org/10.1016/j.avsg.2016.02.009

Background Intermittent claudication (IC) is a common and debilitating symptom of peripheral arterial disease and is associated with a significant reduction in a sufferer's quality of life. Guidelines recommend a supervised exercise program (SEP) as... Read More about A Systematic Review of the Uptake and Adherence Rates to Supervised Exercise Programs in Patients with Intermittent Claudication.

Effect of age and sex on efficacy and tolerability of β blockers in patients with heart failure with reduced ejection fraction: individual patient data meta-analysis (2016)
Journal Article
Kotecha, D., Manzano, L., Krum, H., Rosano, G., Holmes, J., Altman, D. G., …Flather, M. D. (2016). Effect of age and sex on efficacy and tolerability of β blockers in patients with heart failure with reduced ejection fraction: individual patient data meta-analysis. BMJ, 353, i1855. https://doi.org/10.1136/bmj.i1855

© BMJ Publishing Group Ltd 2016. OBJECTIVES: To determine the efficacy and tolerability of β blockers in a broad age range of women and men with heart failure with reduced ejection fraction (HFrEF) by pooling individual patient data from placebo cont... Read More about Effect of age and sex on efficacy and tolerability of β blockers in patients with heart failure with reduced ejection fraction: individual patient data meta-analysis.

Is the diagnostic coding position of acute heart failure related to mortality? A report from the Euro Heart Failure Survey-1 (2016)
Journal Article
Shoaib, A., Farag, M., Nasir, M., John, J., Gupta, S., Pellicori, P., …Cleland, J. G. (2016). Is the diagnostic coding position of acute heart failure related to mortality? A report from the Euro Heart Failure Survey-1. European journal of heart failure, 18(5), 556-563. https://doi.org/10.1002/ejhf.505

© 2016 The Authors. European Journal of Heart Failure. Aims Most studies on acute heart failure (HF) exploring the relationship between admissions to hospital for HF and subsequent outcomes have focused only on HF coded as the primary diagnosis, but... Read More about Is the diagnostic coding position of acute heart failure related to mortality? A report from the Euro Heart Failure Survey-1.

A non-invasive, home-based EEG hypoglycaemia warning system for personal monitoring using skin surface electrodes : a single-case feasibility study (2016)
Journal Article
Clewett, C. J., Langley, P., Bateson, A. D., Asghar, A., & Wilkinson, A. J. (2016). A non-invasive, home-based EEG hypoglycaemia warning system for personal monitoring using skin surface electrodes : a single-case feasibility study. Health Technology Letters, 3(1), 2-5. https://doi.org/10.1049/htl.2015.0037

Hypoglycaemia unawareness is a common condition associated with increased risk of severe hypoglycaemia. The purpose of the authors' study was to develop a simple to use, home-based and non-invasive hypoglycaemia warning system based on electroencepha... Read More about A non-invasive, home-based EEG hypoglycaemia warning system for personal monitoring using skin surface electrodes : a single-case feasibility study.

The dietary flavonol quercetin ameliorates angiotensin II-induced redox signaling imbalance in a human umbilical vein endothelial cell model of endothelial dysfunction via ablation of p47ᵖʰᵒˣ expression (2016)
Journal Article
Jones, H. S., Gordon, A., Magwenzi, S. G., Naseem, K., Atkin, S. L., & Courts, F. L. (2016). The dietary flavonol quercetin ameliorates angiotensin II-induced redox signaling imbalance in a human umbilical vein endothelial cell model of endothelial dysfunction via ablation of p47ᵖʰᵒˣ expression. Molecular Nutrition and Food Research, 60(4), 787-797. https://doi.org/10.1002/mnfr.201500751

Scope: Quercetin is reported to reduce blood pressure in hypertensive but not normotensive humans, but the role of endothelial redox signaling in this phenomenon has not been assessed. This study investigated the effects of physiologically obtainable... Read More about The dietary flavonol quercetin ameliorates angiotensin II-induced redox signaling imbalance in a human umbilical vein endothelial cell model of endothelial dysfunction via ablation of p47ᵖʰᵒˣ expression.

The contribution of caregiver psychosocial factors to distress associated with behavioural and psychological symptoms in dementia (2016)
Journal Article
Feast, A., Orrell, M., Russell, I., Charlesworth, G., & Moniz-Cook, E. (2017). The contribution of caregiver psychosocial factors to distress associated with behavioural and psychological symptoms in dementia. International journal of geriatric psychiatry, 32(1), 76-85. https://doi.org/10.1002/gps.4447

Copyright © 2016 John Wiley & Sons, Ltd. Objective: The objective of the study is to examine caregiver factors as predictors of BPSD-related distress and their potential mechanisms. Method: Informal caregivers of people with dementia (n = 157) recr... Read More about The contribution of caregiver psychosocial factors to distress associated with behavioural and psychological symptoms in dementia.

Sex-dependent association between erythrocyte n-3 PUFA and type 2 diabetes in older overweight people (2016)
Journal Article
Abbott, K. A., Veysey, M., Lucock, M., Niblett, S., King, K., Burrows, T., & Garg, M. L. (2016). Sex-dependent association between erythrocyte n-3 PUFA and type 2 diabetes in older overweight people. British Journal of Nutrition, 115(8), 1379-1386. https://doi.org/10.1017/s0007114516000258

Copyright © The Authors 2016. The association between n-3 PUFA intake and type 2 diabetes (T2D) is unclear, and studies relating objective biomarkers of n-3 PUFA consumption to diabetic status remain limited. The aim of this study was to determine w... Read More about Sex-dependent association between erythrocyte n-3 PUFA and type 2 diabetes in older overweight people.

Expression and function of transient receptor potential channels in the female bovine reproductive tract (2016)
Journal Article
Ghavideldarestani, M., Atkin, S. L., Leese, H. J., & Sturmey, R. G. (2016). Expression and function of transient receptor potential channels in the female bovine reproductive tract. Theriogenology, 86(2), 551-561. https://doi.org/10.1016/j.theriogenology.2016.02.005

© 2016 Elsevier Inc. The epithelium lining the oviduct is critical for early reproductive events, many of which are mediated via intracellular calcium ions. Despite this, little is known about the regulation of calcium homeostasis in the oviductal ep... Read More about Expression and function of transient receptor potential channels in the female bovine reproductive tract.

The International Pulsar Timing Array: First data release (2016)
Journal Article
Verbiest, J. P., Lentati, L., Hobbs, G., Van Haasteren, R., Demorest, P. B., Janssen, G. H., …Zhu, X. J. (2016). The International Pulsar Timing Array: First data release. Monthly notices of the Royal Astronomical Society, 458(2), 1267-1288. https://doi.org/10.1093/mnras/stw347

The highly stable spin of neutron stars can be exploited for a variety of (astro)physical investigations. In particular, arrays of pulsars with rotational periods of the order of milliseconds can be used to detect correlated signals such as those cau... Read More about The International Pulsar Timing Array: First data release.

Was acupuncture developed by Han Dynasty Chinese anatomists? (2016)
Journal Article
Shaw, V., & Mclennan, A. K. (2016). Was acupuncture developed by Han Dynasty Chinese anatomists?. Anatomical Record: Advances in Integrative Anatomy and Evolutionary Biology, 299(5), 643-659. https://doi.org/10.1002/ar.23325

Anatomical dissection has begun to reveal striking similarities between gross anatomical structures and the system of nomenclature used in traditional Chinese acupuncture. This paper argues that acupuncture point nomenclature is rooted in systematic... Read More about Was acupuncture developed by Han Dynasty Chinese anatomists?.

Current advances in ligand design for inorganic positron emission tomography tracers ⁶⁸Ga, ⁶⁴Cu, ⁸⁹Zr and ⁴⁴Sc (2016)
Journal Article
Price, T. W., Greenman, J., & Stasiuk, G. J. (2016). Current advances in ligand design for inorganic positron emission tomography tracers ⁶⁸Ga, ⁶⁴Cu, ⁸⁹Zr and ⁴⁴Sc. Dalton Transactions : an international journal of inorganic chemistry, 45(40), 15702-15724. https://doi.org/10.1039/c5dt04706d

A key part of the development of metal based Positron Emission Tomography probes is the chelation of the radiometal. In this review the recent developments in the chelation of four positron emitting radiometals, 68Ga, 64Cu, 89Zr and 44Sc, are explore... Read More about Current advances in ligand design for inorganic positron emission tomography tracers ⁶⁸Ga, ⁶⁴Cu, ⁸⁹Zr and ⁴⁴Sc.

How does rhinovirus cause the common cold cough? (2016)
Journal Article
Atkinson, S. K., Sadofsky, L. R., & Morice, A. H. (2016). How does rhinovirus cause the common cold cough?. BMJ Open Respiratory Research, 3(1), Article e000118. https://doi.org/10.1136/bmjresp-2015-000118

© 2016, BMJ Publishing Group. All rights reserved. Cough is a protective reflex to prevent aspiration and can be triggered by a multitude of stimuli. The commonest form of cough is caused by upper respiratory tract infection and has no benefit to the... Read More about How does rhinovirus cause the common cold cough?.