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Social and clinical determinants of preferences and their achievement at the end of life: Prospective cohort study of older adults receiving palliative care in three countries (2017)
Journal Article
Higginson, I. J., Bennett, E., Daveson, B. A., Cooper, F., Morrison, R. S., Yi, D., …Wei, G. (2017). Social and clinical determinants of preferences and their achievement at the end of life: Prospective cohort study of older adults receiving palliative care in three countries. BMC Geriatrics, 17(1), https://doi.org/10.1186/s12877-017-0648-4

© 2017 The Author(s). Background: Achieving choice is proposed as a quality marker. But little is known about what influences preferences especially among older adults. We aimed to determine and compare, across three countries, factors associated wit... Read More

What is the impact of population ageing on the future provision of end-of-life care? Population-based projections of place of death (2017)
Journal Article
Bone, A. E., Gomes, B., Etkind, S. N., Verne, J., Murtagh, F. E., Evans, C. J., & Higginson, I. J. (2018). What is the impact of population ageing on the future provision of end-of-life care? Population-based projections of place of death. Palliative medicine, 32(2), 329-336. https://doi.org/10.1177/0269216317734435

© 2017, © The Author(s) 2017. Background: Population ageing represents a global challenge for future end-of-life care. Given new trends in place of death, it is vital to examine where the rising number of deaths will occur in future years and implica... Read More

Prescribing non-opioid drugs in end-stage kidney disease (2017)
Journal Article
Wilcock, A., Charlesworth, S., Twycross, R., Waddington, A., Worthington, O., Murtagh, F. E., …Kotlinska-Lemieszek, A. (2017). Prescribing non-opioid drugs in end-stage kidney disease. Journal of pain and symptom management, 54(5), 776-787. https://doi.org/10.1016/j.jpainsymman.2017.08.014

Palliative care services are increasingly involved in the care of patients with chronic kidney disease, either alone or as a comorbid condition. Because renal impairment often changes the pharmacokinetic and/or pharmacodynamic effects of a drug, this... Read More

Systematic review of pharmacological therapies for the management of ischaemic pain in patients with non-reconstructable critical limb ischaemia (2017)
Journal Article
Laoire, Á. N., & Murtagh, F. E. (2018). Systematic review of pharmacological therapies for the management of ischaemic pain in patients with non-reconstructable critical limb ischaemia. BMJ supportive & palliative care, 8(4), 400-410. https://doi.org/10.1136/bmjspcare-2017-001359

Background Critical limb ischaemia (CLI) is a severe manifestation of peripheral arterial disease, characterised by chronic ischaemic rest pain, ulcers or gangrene. Management of ischaemic pain is challenging in patients with no options for revascula... Read More

Phase of Illness in palliative care: Cross-sectional analysis of clinical data from community, hospital and hospice patients (2017)
Journal Article
Mather, H., Guo, P., Firth, A., Davies, J. M., Sykes, N., Landon, A., & Murtagh, F. E. (2018). Phase of Illness in palliative care: Cross-sectional analysis of clinical data from community, hospital and hospice patients. Palliative medicine, 32(2), 404-412. https://doi.org/10.1177/0269216317727157

© 2017, © The Author(s) 2017. Background: Phase of Illness describes stages of advanced illness according to care needs of the individual, family and suitability of care plan. There is limited evidence on its association with other measures of sympto... Read More

Time to improve informed consent for dialysis: an international perspective (2017)
Journal Article
Murtagh, F. E., Brennan, F., Stewart, C., Burgess, H., Davison, S. N., Moss, A. H., …Brown, M. (2017). Time to improve informed consent for dialysis: an international perspective. Clinical journal of the American Society of Nephrology, 12(6), 1001-1009. https://doi.org/10.2215/CJN.09740916

The literature reveals that current nephrology practice in obtaining informed consent for dialysis falls short of ethical and legal requirements. Meeting these requirements represents a significant challenge, especially because the benefits and risks... Read More

Development of a core outcome set for disease modification trials in mild to moderate dementia: A systematic review, patient and public consultation and consensus recommendations (2017)
Journal Article
Webster, L., Groskreutz, D., Grinbergs-Saull, A., Howard, R., O’Brien, J. T., Mountain, G., …Livingston, G. (2017). Development of a core outcome set for disease modification trials in mild to moderate dementia: A systematic review, patient and public consultation and consensus recommendations. Health Technology Assessment, 21(26), 1-192. https://doi.org/10.3310/hta21260

© Queen’s Printer and Controller of HMSO 2017. Background: There is currently no disease-modifying treatment available to halt or delay the progression of the disease pathology in dementia. An agreed core set of the best-available and most appropriat... Read More

How many people will need palliative care in 2040? Past trends, future projections and implications for services (2017)
Journal Article
Etkind, S. N., Bone, A. E., Gomes, B., Lovell, N., Evans, C. J., Higginson, I. J., & Murtagh, F. E. M. (2017). How many people will need palliative care in 2040? Past trends, future projections and implications for services. BMC medicine, 15(1), https://doi.org/10.1186/s12916-017-0860-2

Background: Current estimates suggest that approximately 75% of people approaching the end-of-life may benefit from palliative care. The growing numbers of older people and increasing prevalence of chronic illness in many countries mean that more peo... Read More

Strategies to address the shortcomings of commonly used advanced chronic heart failure descriptors to improve recruitment in palliative care research: A parallel mixed-methods feasibility study (2017)
Journal Article
Kane, P. M., Murtagh, F. E., Ryan, K. R., Brice, M., Mahon, N. G., McAdam, B., …on behalf of BuildCARE, . (2018). Strategies to address the shortcomings of commonly used advanced chronic heart failure descriptors to improve recruitment in palliative care research: A parallel mixed-methods feasibility study. Palliative medicine, 32(2), 517-524. https://doi.org/10.1177/0269216317706426

Background: Recruitment challenges contribute to the paucity of palliative care research with advanced chronic heart failure patients. Aim: To describe the challenges and outline strategies of recruiting advanced chronic heart failure patients. Des... Read More

A systematic review of the effectiveness of palliative interventions to treat rectal tenesmus in cancer (2017)
Journal Article
Ní Laoire, Á., Fettes, L., & Murtagh, F. E. (2017). A systematic review of the effectiveness of palliative interventions to treat rectal tenesmus in cancer. Palliative medicine, 31(10), 975-981. https://doi.org/10.1177/0269216317697897

Background: Rectal tenesmus is a distressing symptom in patients with advanced cancer and challenging to treat. There is lack of consensus on the appropriate management of tenesmus in this patient population. Aim: To identify and examine the effecti... Read More

Development of a patient-reported palliative care-specific health classification system: the POS-E (2017)
Journal Article
Murtagh, F. E. M., Murtagh, F. E., Dzingina, M., Higginson, I. J., McCrone, P., & Murtagh, F. (2017). Development of a patient-reported palliative care-specific health classification system: the POS-E. Patient, 10(3), 353-365. https://doi.org/10.1007/s40271-017-0224-1

Background Generic preference-based measures are commonly used to estimate quality-adjusted life-years (QALYs) to inform resource-allocation decisions. However, concerns have been raised that generic measures may be inappropriate in palliative care.... Read More

Funding models in palliative care: lessons from international experience (2017)
Journal Article
Groeneveld, E. I., Cassel, J. B., Murtagh, F. E., Merino, T. G. B., Murtagh, F. E., Csikos, A., …Murtagh, F. E. M. (2017). Funding models in palliative care: lessons from international experience. Palliative medicine, 31(4), 296-305. https://doi.org/10.1177/0269216316689015

Background: Funding models influence provision and development of palliative care services. As palliative care integrates into mainstream health care provision, opportunities to develop funding mechanisms arise. However, little has been reported on w... Read More