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Design and rationale of two phase 3 randomised controlled trials (Cough-1 and cough-2) of gefapixant, a P2X3 receptor antagonist, in refractory or unexplained chronic cough (2020)
Journal Article
Muccino, D. R., Morice, A. H., Birring, S. S., Dicpinigaitis, P. V., Pavord, I. D., Assaid, C., …Smith, J. A. (2020). Design and rationale of two phase 3 randomised controlled trials (Cough-1 and cough-2) of gefapixant, a P2X3 receptor antagonist, in refractory or unexplained chronic cough. ERJ Open Research, 6(4), Article 00284-2020. https://doi.org/10.1183/23120541.00284-2020

Background: We present study designs, dose selection and preliminary patient characteristics from two phase 3 clinical trials of gefapixant, a P2X3 receptor antagonist, in refractory chronic cough (RCC) or unexplained chronic cough (UCC). Methods: CO... Read More about Design and rationale of two phase 3 randomised controlled trials (Cough-1 and cough-2) of gefapixant, a P2X3 receptor antagonist, in refractory or unexplained chronic cough.

An audit of COPD: Diagnosis and management in general practice (2020)
Journal Article
Hamad, G., Rigby, A., & Morice, A. H. (2020). An audit of COPD: Diagnosis and management in general practice. ERJ Open Research, 6(4), Article 00330-2020. https://doi.org/10.1183/23120541.00330-2020

Introduction: COPD is a spectrum of disorders primarily caused by smoking and characterised by progressive, not fully reversible airflow obstruction with a forced expiratory volume in 1 s (FEV1)/forced vital capacity (FVC) ratio

Soundscape assessment: Towards a validated translation of perceptual attributes in different languages (2020)
Conference Proceeding
Aletta, F., Oberman, T., Axelsson, Ö., Xie, H., Zhang, Y., Lau, S. K., …Kang, J. (2020). Soundscape assessment: Towards a validated translation of perceptual attributes in different languages. In INTER-NOISE and NOISE-CON Congress and Conference Proceedings 2020 ( 3137-3146)

The recently published ISO/TS 12913-2:2018 standard aims to provide researchers and practitioners around the world with a reliable questionnaire for soundscape characterization. The ISO Technical Specifications report protocols and attributes grounde... Read More about Soundscape assessment: Towards a validated translation of perceptual attributes in different languages.

Stress fields of ancient seismicity recorded in the dynamic geometry of pseudotachylyte in the Outer Hebrides Fault Zone, UK (2020)
Journal Article
Campbell, L., Lloyd, G., Phillips, R., Walcott, R., & Holdsworth, R. (2021). Stress fields of ancient seismicity recorded in the dynamic geometry of pseudotachylyte in the Outer Hebrides Fault Zone, UK. Journal of the Geological Society, 178(1), Article jgs2020-101. https://doi.org/10.1144/jgs2020-101

Heterogeneous sequences of exhumed fault rocks preserve a record of the long-term evolution of fault strength and deformation behaviour during prolonged tectonic activity. Along the Outer Hebrides Fault Zone (OHFZ) in NW Scotland, numerous pseudotach... Read More about Stress fields of ancient seismicity recorded in the dynamic geometry of pseudotachylyte in the Outer Hebrides Fault Zone, UK.

Azithromycin for sarcoidosis cough: an open label exploratory clinical trial (2020)
Journal Article
Fraser, S. D., Thackray-Nocera, S., Shepherd, M., Flockton, R., Wright, C., Sheedy, W., …Hart, S. P. (2020). Azithromycin for sarcoidosis cough: an open label exploratory clinical trial. ERJ Open Research, 6(4), Article 00534. https://doi.org/10.1183/23120541.00534-2020

Background: Chronic cough is a distressing symptom for many people with pulmonary sarcoidosis. Continuous treatment with a macrolide antibiotic may improve cough. We aimed to assess the potential efficacy of azithromycin in patients with sarcoidosis... Read More about Azithromycin for sarcoidosis cough: an open label exploratory clinical trial.

Sporopollenin as a dilution agent in artificial diets for solitary bees (2020)
Journal Article
Tainsh, F., Woodmansey, S. R., Austin, A. J., Bagnall, T. E., & Gilbert, J. D. (in press). Sporopollenin as a dilution agent in artificial diets for solitary bees. Apidologie, https://doi.org/10.1007/s13592-020-00801-1

Nutritional studies often require precise control of nutrients via dilution of artificial diets with indigestible material, but such studies in bees are limited. Common diluents like cellulose typically result in total mortality of bee larvae, making... Read More about Sporopollenin as a dilution agent in artificial diets for solitary bees.

Feasibility randomised controlled trial examining the effects of the Anti-Doping Values in Coach Education (ADVICE) mobile application on doping knowledge and attitudes towards doping among grassroots coaches (2020)
Journal Article
Nicholls, A. R., Fairs, L. R., Plata-Andrés, M., Bailey, ​., Cope, ​., Madigan, ​. D. J., …​ Chanal​, ​. (2020). Feasibility randomised controlled trial examining the effects of the Anti-Doping Values in Coach Education (ADVICE) mobile application on doping knowledge and attitudes towards doping among grassroots coaches. BMJ Open Sport and Exercise Medicine, 6(1), Article 000800. https://doi.org/10.1136/bmjsem-2020-000800

Objectives Sports coaches are influential in whether athletes dope, but receive very little antidoping education, particularly within entry-level coaching qualifications. We tested the feasibility of an antidoping intervention, delivered via a mobile... Read More about Feasibility randomised controlled trial examining the effects of the Anti-Doping Values in Coach Education (ADVICE) mobile application on doping knowledge and attitudes towards doping among grassroots coaches.

An investigation into the effect of oxLDL and cyclic nucleotides on platelet cytoskeletal function (2020)
Thesis
Ahmed, Y. (2020). An investigation into the effect of oxLDL and cyclic nucleotides on platelet cytoskeletal function. (Thesis). Hull York Medical School, The University of Hull and The University of York. Retrieved from https://hull-repository.worktribe.com/output/4200904

Atherosclerosis is a major underlying cause in cardiovascular disease and a significant health concern in developed countries. Part of the mechanism by which platelets are linked to this process is via their activation by oxidised Low-Density Lipopro... Read More about An investigation into the effect of oxLDL and cyclic nucleotides on platelet cytoskeletal function.

Deep drilling reveals massive shifts in evolutionary dynamics after formation of ancient ecosystem (2020)
Journal Article
Wilke, T., Hauffe, T., Jovanovska, E., Cvetkoska, A., Donders, T., Ekschmitt, K., …Wagner, B. (2020). Deep drilling reveals massive shifts in evolutionary dynamics after formation of ancient ecosystem. Science Advances, 6(40), eabb2943. https://doi.org/10.1126/sciadv.abb2943

The scarcity of high-resolution empirical data directly tracking diversity over time limits our understanding of speciation and extinction dynamics and the drivers of rate changes. Here, we analyze a continuous species-level fossil record of endemic... Read More about Deep drilling reveals massive shifts in evolutionary dynamics after formation of ancient ecosystem.

Size variations in foraminifers from the early Permian to the Late Triassic: Implications for the Guadalupian-Lopingian and the Permian-Triassic mass extinctions (2020)
Journal Article
Feng, Y., Song, H., & Bond, D. P. (2020). Size variations in foraminifers from the early Permian to the Late Triassic: Implications for the Guadalupian-Lopingian and the Permian-Triassic mass extinctions. Paleobiology, 46(4), 511-532. https://doi.org/10.1017/pab.2020.37

The final 10 Myr of the Paleozoic saw two of the biggest biological crises in Earth history: the middlePermian extinction (often termed the Guadalupian–Lopingian extinction [GLE]) that was followed 7–8 Myr later by Earth's most catastrophic loss of d... Read More about Size variations in foraminifers from the early Permian to the Late Triassic: Implications for the Guadalupian-Lopingian and the Permian-Triassic mass extinctions.

Dynamic Changes in Circulating Endocrine FGF19 Subfamily and Fetuin-A in Response to Intralipid and Insulin Infusions in Healthy and PCOS Women (2020)
Journal Article
Ramanjaneya, M., Bensila, M., Bettahi, I., Jerobin, J., Samra, T. A., Aye, M. M., …Abou-Samra, A. B. (2020). Dynamic Changes in Circulating Endocrine FGF19 Subfamily and Fetuin-A in Response to Intralipid and Insulin Infusions in Healthy and PCOS Women. Frontiers in endocrinology, 11, Article 568500. https://doi.org/10.3389/fendo.2020.568500

© Copyright © 2020 Ramanjaneya, Bensila, Bettahi, Jerobin, Samra, Aye, Alkasem, Siveen, Sathyapalan, Skarulis, Atkin and Abou-Samra. Background: The fibroblast growth factors (FGF) 19 subfamily, also referred to as endocrine FGFs, includes FGF19, FGF... Read More about Dynamic Changes in Circulating Endocrine FGF19 Subfamily and Fetuin-A in Response to Intralipid and Insulin Infusions in Healthy and PCOS Women.

Increased MicroRNA Levels in Women With Polycystic Ovarian Syndrome but Without Insulin Resistance: A Pilot Prospective Study (2020)
Journal Article
Butler, A. E., Ramachandran, V., Cunningham, T. K., David, R., Gooderham, N. J., Benurwar, M., …Atkin, S. L. (2020). Increased MicroRNA Levels in Women With Polycystic Ovarian Syndrome but Without Insulin Resistance: A Pilot Prospective Study. Frontiers in endocrinology, 11, Article 571357. https://doi.org/10.3389/fendo.2020.571357

© Copyright © 2020 Butler, Ramachandran, Cunningham, David, Gooderham, Benurwar, Dargham, Hayat, Sathyapalan, Najafi-Shoushtari and Atkin. Background: Small noncoding microRNA (miRNA) have regulatory functions in polycystic ovary syndrome (PCOS) that... Read More about Increased MicroRNA Levels in Women With Polycystic Ovarian Syndrome but Without Insulin Resistance: A Pilot Prospective Study.

Wound healing: cellular mechanisms and pathological outcomes (2020)
Journal Article
Wilkinson, H. N., & Hardman, M. J. (2020). Wound healing: cellular mechanisms and pathological outcomes. Open Biology, 10(9), Article 200223. https://doi.org/10.1098/rsob.200223

Wound healing is a complex, dynamic process supported by a myriad of cellular events that must be tightly coordinated to efficiently repair damaged tissue. Derangement in wound-linked cellular behaviours, as occurs with diabetes and ageing, can lead... Read More about Wound healing: cellular mechanisms and pathological outcomes.

Heat Acclimation for Special Populations (2020)
Book
Sunderland, C., Garrett, A. T., Maxwell, N. S., & Périard, J. (Eds.). (2020). Heat Acclimation for Special Populations. Frontiers Media. https://doi.org/10.3389/978-2-88966-018-6

This Heat Acclimation for Special Populations' Research Topic questions the ‘one size fits all’ approach for heat adaptation and that it may not be appropriate for all populations. Therefore, to highlight these differences we endeavoured to collect a... Read More about Heat Acclimation for Special Populations.

The effectiveness and cost-effectiveness of hospital-based specialist palliative care for adults with advanced illness and their caregivers (2020)
Journal Article
Bajwah, S., Oluyase, A. O., Yi, D., Gao, W., Evans, C. J., Grande, G., …Higginson, I. J. (2020). The effectiveness and cost-effectiveness of hospital-based specialist palliative care for adults with advanced illness and their caregivers. The Cochrane database of systematic reviews, 2020(9), Article CD012780. https://doi.org/10.1002/14651858.CD012780.pub2

Background Serious illness is often characterised by physical/psychological problems, family support needs, and high healthcare resource use. Hospital‐based specialist palliative care (HSPC) has developed to assist in better meeting the needs of pat... Read More about The effectiveness and cost-effectiveness of hospital-based specialist palliative care for adults with advanced illness and their caregivers.

The Anime Boom in the United States. Lessons for Global Creative Industries by Michal Daliot-Bul and Nissim Otmazgin. Reviewed by Manuel Hernandez-Perez. (2020)
Journal Article
Hernandez-Perez, M. (2020). The Anime Boom in the United States. Lessons for Global Creative Industries by Michal Daliot-Bul and Nissim Otmazgin. Reviewed by Manuel Hernandez-Perez. International Journal of Communication, 14, 5001-5003

Hernández-Pérez, M. (2020). The Anime Boom in the United States. Lessons for Global Creative Industries by Michal Daliot-Bul and Nissim Otmazgin. Reviewed by Manuel Hernandez-Perez. International Journal of Communication, 14, 5001-5003. doi:1932–8036... Read More about The Anime Boom in the United States. Lessons for Global Creative Industries by Michal Daliot-Bul and Nissim Otmazgin. Reviewed by Manuel Hernandez-Perez..

Twenty-five years of the EdFED scale: a useful scale for measuring mealtime difficulty in older people with dementia (2020)
Journal Article
Watson, R. (2020). Twenty-five years of the EdFED scale: a useful scale for measuring mealtime difficulty in older people with dementia. Nursing standard : official newspaper of the Royal College of Nursing, 35(10), 52-55. https://doi.org/10.1111/j.1365-

The 'EdFED' is the Edinburgh Feeding Evaluation in Dementia (EdFED) scale. 'Ed' points to where the scale was developed-Edinburgh University-and 'FED' is shorthand for 'feeding'. Finding a meaningful acronym is always challenging, but this one seems... Read More about Twenty-five years of the EdFED scale: a useful scale for measuring mealtime difficulty in older people with dementia.