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All Outputs (4)

miRNA expression in acute myeloid leukaemia: new targets for therapy? (2022)
Journal Article
Fletcher, D., Brown, E., Javadala, J., Uysal-Onganer, P., & Guinn, B. (in press). miRNA expression in acute myeloid leukaemia: new targets for therapy?. eJHaem, https://doi.org/10.1002/jha2.441

Recent studies have shown that short non-coding RNAs, known as microRNAs (miRNAs) and their dysregulation, are implicated in the pathogenesis of acute myeloid leukaemia (AML). This is due to their role in the control of gene expression in a variety o... Read More about miRNA expression in acute myeloid leukaemia: new targets for therapy?.

microRNA expression in acute myeloid leukaemia: New targets for therapy? (2022)
Journal Article
Fletcher, D., Brown, E., Javadala, J., Uysal-Onganer, P., & Guinn, B. (2022). microRNA expression in acute myeloid leukaemia: New targets for therapy?. eJHaem, 3(3), 596-608. https://doi.org/10.1002/jha2.441

Recent studies have shown that short non-coding RNAs, known as microRNAs (miRNAs) and their dysregulation, are implicated in the pathogenesis of acute myeloid leukaemia (AML). This is due to their role in the control of gene expression in a variety o... Read More about microRNA expression in acute myeloid leukaemia: New targets for therapy?.

Identification of the molecular pathways involved in paediatric and adult acute myeloid leukaemia (2022)
Thesis
Brown, E. (2022). Identification of the molecular pathways involved in paediatric and adult acute myeloid leukaemia. (Thesis). University of Hull. Retrieved from https://hull-repository.worktribe.com/output/4224412

Acute myeloid leukaemia (AML) affects 3100 people every year in the UK, around 1% of whom are under 19 years of age. Despite improvements in immunotherapeutic treatment opportunities for AML, the rates of survival particularly in adults remain poor.... Read More about Identification of the molecular pathways involved in paediatric and adult acute myeloid leukaemia.