Skin Aging in Long-Lived Naked Mole-Rats Is Accompanied by Increased Expression of Longevity-Associated and Tumor Suppressor Genes

Fatima, Iqra; Chen, Guodong; Botchkareva, Natalia V; Sharov, Andrey A; Thornton, Daniel; Wilkinson, Holly N.; Hardman, Matthew J.; Grutzkau, Andreas; Pedro de Magalhaes, Joao; Seluanov, Andrei; St J Smith, Ewan; Gorbunova, Vera; Mardaryev, Andrei N; Faulkes, Chris G; Botchkarev, Vladimir A

doi:10.1016/j.jid.2022.04.028

All Outputs (2)

Epithelial arginase-1 is a key mediator of age-associated delayed healing in vaginal injury (2022)
Journal Article
Wilkinson, H. N., Reubinoff, B., Shveiky, D., Hardman, M. J., & Menachem-Zidon, O. B. (2022). Epithelial arginase-1 is a key mediator of age-associated delayed healing in vaginal injury. Frontiers in endocrinology, 13, Article 927224. https://doi.org/10.3389/fendo.2022.927224

Pelvic organ prolapse is a disorder that substantially affects the quality of life of millions of women worldwide. The greatest risk factors for prolapse are increased parity and older age, with the largest group requiring surgical intervention being... Read More about Epithelial arginase-1 is a key mediator of age-associated delayed healing in vaginal injury.

Skin Aging in Long-Lived Naked Mole-Rats Is Accompanied by Increased Expression of Longevity-Associated and Tumor Suppressor Genes (2022)
Journal Article
Fatima, I., Chen, G., Botchkareva, N. V., Sharov, A. A., Thornton, D., Wilkinson, H. N., …Botchkarev, V. A. (in press). Skin Aging in Long-Lived Naked Mole-Rats Is Accompanied by Increased Expression of Longevity-Associated and Tumor Suppressor Genes. Journal of Investigative Dermatology, https://doi.org/10.1016/j.jid.2022.04.028

Naked mole-rats (NMRs) (Heterocephalus glaber) are long-lived mammals that possess a natural resistance to cancer and other age-related pathologies, maintaining a healthy life span >30 years. In this study, using immunohistochemical and RNA-sequencin... Read More about Skin Aging in Long-Lived Naked Mole-Rats Is Accompanied by Increased Expression of Longevity-Associated and Tumor Suppressor Genes.