Skip to main content

Research Repository

Advanced Search

All Outputs (56)

Radical cystectomy (bladder removal) against intravesical BCG immunotherapy for high-risk non-muscle invasive bladder cancer (BRAVO): a protocol for a randomised controlled feasibility study (2017)
Journal Article
Noon, A. P., Chahal, R., Dooldeniya, M., Koenig, P., Catto, J. W. F., Oughton, J. B., …Catto, J. (2017). Radical cystectomy (bladder removal) against intravesical BCG immunotherapy for high-risk non-muscle invasive bladder cancer (BRAVO): a protocol for a randomised controlled feasibility study. BMJ open, 7(8), e017913. https://doi.org/10.1136/bmjopen-2017-017913

Introduction High-risk non-muscle invasive bladder cancer (HRNMIBC) is a heterogeneous disease that can be difficult to predict. While around 25% of cancers progress to invasion and metastases, the remaining majority of tumours remain within the blad... Read More about Radical cystectomy (bladder removal) against intravesical BCG immunotherapy for high-risk non-muscle invasive bladder cancer (BRAVO): a protocol for a randomised controlled feasibility study.

Cost-effectiveness of outpatient parenteral antibiotic therapy: a simulation modelling approach (2017)
Journal Article
Vargas-Palacios, A., Meads, D. M., Twiddy, M., Murray, C. C., Hulme, C., Mitchell, E. D., …Minton, J. (2017). Cost-effectiveness of outpatient parenteral antibiotic therapy: a simulation modelling approach. The journal of antimicrobial chemotherapy, 72(8), 2392-2400. https://doi.org/10.1093/jac/dkx123

© The Author 2017. Published by Oxford University Press on behalf of the British Society for Antimicrobial Chemotherapy. All rights reserved. Objectives: In the UK, patients who require intravenous antimicrobial (IVA) treatment may receive this in th... Read More about Cost-effectiveness of outpatient parenteral antibiotic therapy: a simulation modelling approach.

NIHR Liver/Renal Biomarker Programme Final Report: Evaluating the benefits for patients and the NHS of new and existing biological fluid biomarkers in liver and renal disease (2017)
Report
Selby, P., Banks, R., Gregory, W., Hewison, J., Rosenberg, W., Altman, D., …Hutchinson, M. (2017). NIHR Liver/Renal Biomarker Programme Final Report: Evaluating the benefits for patients and the NHS of new and existing biological fluid biomarkers in liver and renal disease. Southampton: NIHR

Protein biomarkers are naturally occurring substances that can be measured, often in fluids such as blood or urine, and which provide information about a patient and their illness. Different diseases have different biomarkers. When people become ill,... Read More about NIHR Liver/Renal Biomarker Programme Final Report: Evaluating the benefits for patients and the NHS of new and existing biological fluid biomarkers in liver and renal disease.

Clinical and cost-effectiveness, safety and acceptability of community intravenous antibiotic service models: CIVAS systematic review (2017)
Journal Article
Murray, C. C., Mitchell, E. D., Czoski Murray, C., Meads, D., Minton, J., Wright, J., & Twiddy, M. (2017). Clinical and cost-effectiveness, safety and acceptability of community intravenous antibiotic service models: CIVAS systematic review. BMJ open, 7(4), Article e013560. https://doi.org/10.1136/bmjopen-2016-013560

OBJECTIVE: Evaluate evidence of the efficacy, safety, acceptability and cost-effectiveness of outpatient parenteral antimicrobial therapy (OPAT) models. DESIGN: A systematic review. DATA SOURCES: MEDLINE, EMBASE, CINAHL, Cochrane Library, National He... Read More about Clinical and cost-effectiveness, safety and acceptability of community intravenous antibiotic service models: CIVAS systematic review.

The patients’ experience of a bladder cancer diagnosis: a systematic review of the qualitative evidence (2017)
Journal Article
Edmondson, A. J., Birtwistle, J. C., Catto, J. W., & Twiddy, M. (2017). The patients’ experience of a bladder cancer diagnosis: a systematic review of the qualitative evidence. Journal of cancer survivorship : research and practice, 11(4), 453-461. https://doi.org/10.1007/s11764-017-0603-6

© 2017, The Author(s). Purpose: Bladder cancer (BC) is a common disease with disparate treatment options and variable outcomes. Despite the disease’s high prevalence, little is known of the lived experience of affected patients. National patient expe... Read More about The patients’ experience of a bladder cancer diagnosis: a systematic review of the qualitative evidence.

The Community IntraVenous Antibiotic Study (CIVAS): a mixed-methods evaluation of patient preferences for and cost-effectiveness of different service models for delivering outpatient parenteral antimicrobial therapy (2017)
Journal Article
Minton, J., Murray, C. C., Meads, D., Hess, S., Vargas-Palacios, A., Mitchell, E., …Twiddy, M. (2017). The Community IntraVenous Antibiotic Study (CIVAS): a mixed-methods evaluation of patient preferences for and cost-effectiveness of different service models for delivering outpatient parenteral antimicrobial therapy. Health Services and Delivery Research, 5(6), 1-272. https://doi.org/10.3310/hsdr05060

Background Outpatient parenteral antimicrobial therapy (OPAT) is widely used in most developed countries, providing considerable opportunities for improved cost savings. However, it is implemented only partially in the UK, using a variety of servi... Read More about The Community IntraVenous Antibiotic Study (CIVAS): a mixed-methods evaluation of patient preferences for and cost-effectiveness of different service models for delivering outpatient parenteral antimicrobial therapy.

Altruism or obligation? The motivations and experience of women who donate oocytes to known recipients in assisted conception treatment: An Interpretative Phenomenological Analysis study. (2016)
Journal Article
Arharya, S., Bryant, L. B., & Twiddy, M. (2017). Altruism or obligation? The motivations and experience of women who donate oocytes to known recipients in assisted conception treatment: An Interpretative Phenomenological Analysis study. Journal of Psychosomatic Obstetrics and Gynecology, 38(1), 4 - 11. https://doi.org/10.1080/0167482X.2016.1233171

Introduction: This qualitative study was conducted to explore the motivations and experience of oocyte donors donating to women known to them. Methods: Three women who donated oocytes to a close relative were interviewed and data were analysed usi... Read More about Altruism or obligation? The motivations and experience of women who donate oocytes to known recipients in assisted conception treatment: An Interpretative Phenomenological Analysis study..

Altruism or obligation? The motivations and experience of women who donate oocytes to known recipients in assisted conception treatment: an interpretative phenomenological analysis study (2016)
Journal Article
Acharya, S., Bryant, L., & Twiddy, M. (2016). Altruism or obligation? The motivations and experience of women who donate oocytes to known recipients in assisted conception treatment: an interpretative phenomenological analysis study. Journal of Psychosomatic Obstetrics and Gynecology, 38(1), 4-11. https://doi.org/10.1080/0167482X.2016.1233171

© 2016 Informa UK Limited, trading as Taylor & Francis Group. Introduction: This qualitative study was conducted to explore the motivations and experience of oocyte donors donating to women known to them. Methods: Three women who donated oocytes to... Read More about Altruism or obligation? The motivations and experience of women who donate oocytes to known recipients in assisted conception treatment: an interpretative phenomenological analysis study.

Diagnosis, medication, and surgical management for patients with trigeminal neuralgia: a qualitative study (2015)
Journal Article
Allsop, M. J., Twiddy, M., Grant, H., Czoski-Murray, C., Mon-Williams, M., Mushtaq, F., …Pavitt, S. (2015). Diagnosis, medication, and surgical management for patients with trigeminal neuralgia: a qualitative study. Acta Neurochirurgica, 157(11), 1925-1933. https://doi.org/10.1007/s00701-015-2515-4

Background Trigeminal neuralgia (TN) is a serious health problem, causing brief, recurrent episodes of stabbing or burning facial pain, which patients describe as feeling like an electric shock. The consequences of living with the condition are seve... Read More about Diagnosis, medication, and surgical management for patients with trigeminal neuralgia: a qualitative study.

Community IntraVenous Antibiotic Study (CIVAS): protocol for an evaluation of patient preferences for and cost-effectiveness of community intravenous antibiotic services (2015)
Journal Article
Czoski Murray, C., Twiddy, M., Meads, D., Hess, S., Wright, J., Mitchell, E. D., …Minton, J. (2015). Community IntraVenous Antibiotic Study (CIVAS): protocol for an evaluation of patient preferences for and cost-effectiveness of community intravenous antibiotic services. BMJ open, 5(8), Article e008965. https://doi.org/10.1136/bmjopen-2015-008965

Introduction: Outpatient parenteral antimicrobial therapy (OPAT) is used to treat a wide range of infections, and is common practice in countries such as the USA and Australia. In the UK, national guidelines (standards of care) for OPAT services have... Read More about Community IntraVenous Antibiotic Study (CIVAS): protocol for an evaluation of patient preferences for and cost-effectiveness of community intravenous antibiotic services.

Measuring patient-perceived continuity of care for patients with long-term conditions in primary care (2014)
Journal Article
Hill, K. M., Twiddy, M., Hewison, J., & House, A. O. (2014). Measuring patient-perceived continuity of care for patients with long-term conditions in primary care. BMC family practice, 15(1), Article 191. https://doi.org/10.1186/s12875-014-0191-8

Background: Continuity of care is widely acknowledged as important for patients with multi-morbidity but simple, service-orientated indices cannot capture the full impact of continuity in complex care delivery systems. The patient’s perspective is im... Read More about Measuring patient-perceived continuity of care for patients with long-term conditions in primary care.

Variability in clinicians' opinions regarding fitness to drive in patients with obstructive sleep apnoea syndrome (OSAS) (2014)
Journal Article
Dwarakanath, A., Twiddy, M., Ghosh, D., Jamson, S. L., Baxter, P. D., & Elliott, M. W. (2015). Variability in clinicians' opinions regarding fitness to drive in patients with obstructive sleep apnoea syndrome (OSAS). Thorax, 70(5), 495-497. https://doi.org/10.1136/thoraxjnl-2014-206180

We evaluated clinicians' current practice for giving advice to patients with obstructive sleep apnoea syndrome. Clinicians were invited to complete a web-based survey and indicate the advice they would give to patients in a number of scenarios about... Read More about Variability in clinicians' opinions regarding fitness to drive in patients with obstructive sleep apnoea syndrome (OSAS).

Understanding causal associations between self-rated health and personal relationships in older adults: a review of evidence from longitudinal studies (2014)
Journal Article
Craigs, C. L., Twiddy, M., Parker, S. G., & West, R. M. (2014). Understanding causal associations between self-rated health and personal relationships in older adults: a review of evidence from longitudinal studies. Archives of Gerontology and Geriatrics, 59(2), 211-226. https://doi.org/10.1016/j.archger.2014.06.009

Abstract Background As we age we experience many life changes in our health, personal relationships, work, or home life which can impact on other aspects of our life. There is compelling evidence that how we feel about our health influences, or is i... Read More about Understanding causal associations between self-rated health and personal relationships in older adults: a review of evidence from longitudinal studies.

Supporting public involvement in research design and grant development: a case study of a public involvement award scheme managed by a National Institute for Health Research (NIHR) Research Design Service (RDS) (2013)
Journal Article
Boote, J. D., Twiddy, M., Baird, W., Birks, Y., Clarke, C., & Beever, D. (2015). Supporting public involvement in research design and grant development: a case study of a public involvement award scheme managed by a National Institute for Health Research (NIHR) Research Design Service (RDS). Health Expectations, 18(5), 1481-1493. https://doi.org/10.1111/hex.12130

BACKGROUND: It is good practice for the public to be involved in developing health research. Resources should be available for researchers to fund the involvement of the public in the development of their grants. OBJECTIVE: To describe a funding awar... Read More about Supporting public involvement in research design and grant development: a case study of a public involvement award scheme managed by a National Institute for Health Research (NIHR) Research Design Service (RDS).

The association between discrepancy in illness representations on distress in stroke patients and carers (2012)
Journal Article
Twiddy, M., House, A., & Jones, F. (2012). The association between discrepancy in illness representations on distress in stroke patients and carers. Journal of psychosomatic research, 72(3), 220-225. https://doi.org/10.1016/j.jpsychores.2011.12.004

Background: To investigate the association between the illness representations of recently diagnosed stroke patients and their carers and distress in the months after stroke. Method: Forty-two stroke survivors and their carers were assessed at 3 m... Read More about The association between discrepancy in illness representations on distress in stroke patients and carers.

Lessons learned from a family-focused weight management intervention for obese and overweight children (2012)
Journal Article
Twiddy, M., Wilson, I., Bryant, M., & Rudolf, M. (2012). Lessons learned from a family-focused weight management intervention for obese and overweight children. Public health nutrition, 15(07), 1310-1317. https://doi.org/10.1017/s1368980011003211

Treatment for childhood obesity is characterised by high attrition rates and failure to achieve weight maintenance. It is therefore important to develop more effective programmes. The aim of the present qualitative study was to explore the views of p... Read More about Lessons learned from a family-focused weight management intervention for obese and overweight children.