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Estimating global injuries morbidity and mortality: methods and data used in the Global Burden of Disease 2017 study (2020)
Journal Article
James, S. L., Bertolacci, G. J., Castle, C. D., Dingels, Z. V., Fox, J. T., Hamilton, E. B., …Vos, T. (2020). Estimating global injuries morbidity and mortality: methods and data used in the Global Burden of Disease 2017 study. Injury Prevention, 26, i125-i153. https://doi.org/10.1136/injuryprev-2019-043531

© Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY. Published by BMJ. BACKGROUND: While there is a long history of measuring death and disability from injuries, modern research methods must account for the wide spectrum of disabili... Read More about Estimating global injuries morbidity and mortality: methods and data used in the Global Burden of Disease 2017 study.

Mapping geographical inequalities in access to drinking water and sanitation facilities in low-income and middle-income countries, 2000-17 (2020)
Journal Article
Reiner, R. C., Local Burden of Disease WaSH Collaborators, , & Soyiri, I. (2020). Mapping geographical inequalities in access to drinking water and sanitation facilities in low-income and middle-income countries, 2000-17. The Lancet global health, 8(9), e1162-e1185. https://doi.org/10.1016/S2214-109X%2820%2930278-3

Background Universal access to safe drinking water and sanitation facilities is an essential human right, recognised in the Sustainable Development Goals as crucial for preventing disease and improving human wellbeing. Comprehensive, high-resolutio... Read More about Mapping geographical inequalities in access to drinking water and sanitation facilities in low-income and middle-income countries, 2000-17.

Mapping geographical inequalities in oral rehydration therapy coverage in low-income and middle-income countries, 2000-17 Local Burden of Disease Diarrhoea Collaborators* (2020)
Journal Article
Local Burden of Disease Diarrhoea Collaborators, , & Soyiri, I. (2020). Mapping geographical inequalities in oral rehydration therapy coverage in low-income and middle-income countries, 2000-17 Local Burden of Disease Diarrhoea Collaborators*. The Lancet global health, 8(8), e1038-e1060. https://doi.org/10.1016/S2214-109X%2820%2930230-8

Background Oral rehydration solution (ORS) is a form of oral rehydration therapy (ORT) for diarrhoea that has the potential to drastically reduce child mortality; yet, according to UNICEF estimates, less than half of children younger than 5 years w... Read More about Mapping geographical inequalities in oral rehydration therapy coverage in low-income and middle-income countries, 2000-17 Local Burden of Disease Diarrhoea Collaborators*.

high INtensity Interval Training In pATiEnts with intermittent claudication (INITIATE): protocol for a multi-centre, proof-of-concept, prospective interventional study (2020)
Journal Article
Pymer, S., Harwood, A., Ibeggazene, S., McGregor, G., Huang, C., Twiddy, M., …Chetter, I. C. (2020). high INtensity Interval Training In pATiEnts with intermittent claudication (INITIATE): protocol for a multi-centre, proof-of-concept, prospective interventional study. BMJ open, 10(7), https://doi.org/10.1136/bmjopen-2020-038825

Introduction: The first-line recommended treatment for patients with intermittent claudication (IC), is a supervised exercise programme (SEP), which includes a minimum of 2 hours exercise per week over a 12-week period. However, provision, uptake, an... Read More about high INtensity Interval Training In pATiEnts with intermittent claudication (INITIATE): protocol for a multi-centre, proof-of-concept, prospective interventional study.

Opioids for breathlessness: a narrative review (2020)
Journal Article
Currow, D. C., Johnson, M. J., Pollack, A., Ferreira, D. H., Kochovska, S., Ekström, M., & Harrison, C. (2020). Opioids for breathlessness: a narrative review. BMJ Supportive & Palliative Care, 10(3), 287-295. https://doi.org/10.1136/bmjspcare-2020-002314

ABSTRACT Chronic breathlessness is a disabling and distressing condition for which there is a growing evidence base for a range of interventions. Non-pharmacological interventions are the mainstay of management and should be optimised prior to use... Read More about Opioids for breathlessness: a narrative review.

Development of a core outcome set to use in the research and assessment of malignant bowel obstruction: protocol for the RAMBO study (2020)
Journal Article
Currow, D. C., Currow, D. C., Murtagh, F. E., Oliver, A., Baddeley, E., Bravington, A., …Boland, J. (2020). Development of a core outcome set to use in the research and assessment of malignant bowel obstruction: protocol for the RAMBO study. BMJ open, 10(6), https://doi.org/10.1136/bmjopen-2020-039154

INTRODUCTION: Studies regarding the management of malignant bowel obstruction (MBO) report conflicting findings. This is partly due to different outcome measures being used to evaluate severity of MBO and the response to treatments. Furthermore, curr... Read More about Development of a core outcome set to use in the research and assessment of malignant bowel obstruction: protocol for the RAMBO study.

Laparoscopic versus open colorectal surgery in the acute setting (LaCeS trial): a multicentre randomized feasibility trial (2020)
Journal Article
Cardozo, W., Baker, R., Berger, C., Chapman, S., Codd, R., Coyne, P., …Brown, J. (in press). Laparoscopic versus open colorectal surgery in the acute setting (LaCeS trial): a multicentre randomized feasibility trial. British journal of surgery, https://doi.org/10.1002/bjs.11703

Abstract Background Approximately 30,000 people per annum undergo major, emergency abdominal, gastrointestinal surgery, of which 36% (~10,800) are carried out for emergency colorectal pathology. Approximately 14% of all patients requiring emergency... Read More about Laparoscopic versus open colorectal surgery in the acute setting (LaCeS trial): a multicentre randomized feasibility trial.

The effects of the iPlayClean education programme on doping attitudes and susceptibility to use banned substances among high-level adolescent athletes from the UK: A cluster-randomised controlled trial (2020)
Journal Article
Thompson, M. A., Morley, D., Abt, G., Nicholls, A. R., Rothwell, M., Cope, E., …Huang, C. (2020). The effects of the iPlayClean education programme on doping attitudes and susceptibility to use banned substances among high-level adolescent athletes from the UK: A cluster-randomised controlled trial. International Journal of Drug Policy, 82, https://doi.org/10.1016/j.drugpo.2020.102820

Background: This study examined the effects of the iPlayClean anti-doping intervention on attitudes towards doping and susceptibility, and whether delivery mode affected the results. Methods: A total of 1,081 high-level UK athletes (14-18 years old... Read More about The effects of the iPlayClean education programme on doping attitudes and susceptibility to use banned substances among high-level adolescent athletes from the UK: A cluster-randomised controlled trial.

Identification of patients with potential palliative care needs: a systematic review of screening tools in primary care (2020)
Journal Article
ElMokhallalati, Y., Bradley, S. H., Chapman, E., Ziegler, L., Murtagh, F. E., Johnson, M. J., & Bennett, M. I. (in press). Identification of patients with potential palliative care needs: a systematic review of screening tools in primary care. Palliative medicine, https://doi.org/10.1177/0269216320929552

Background Despite increasing evidence of the benefits of early access to palliative care, many patients do not receive palliative care in a timely manner. A systematic approach in primary care can facilitate earlier identification of patients with... Read More about Identification of patients with potential palliative care needs: a systematic review of screening tools in primary care.

Mapping geographical inequalities in childhood diarrhoeal morbidity and mortality in low-income and middle-income countries, 2000-17: analysis for the Global Burden of Disease Study 2017 Local Burden of Disease Diarrhoea Collaborators* (2020)
Journal Article
Soyiri, I., & Local Burden of Disease Diarrhoea Collaborators, . (2020). Mapping geographical inequalities in childhood diarrhoeal morbidity and mortality in low-income and middle-income countries, 2000-17: analysis for the Global Burden of Disease Study 2017 Local Burden of Disease Diarrhoea Collaborators*. Lancet, 395(10239), 1779-1801. https://doi.org/10.1016/S0140-6736%2820%2930114-8

Background Across low-income and middle-income countries (LMICs), one in ten deaths in children younger than 5 years is attributable to diarrhoea. The substantial between-country variation in both diarrhoea incidence and mortality is attributable t... Read More about Mapping geographical inequalities in childhood diarrhoeal morbidity and mortality in low-income and middle-income countries, 2000-17: analysis for the Global Burden of Disease Study 2017 Local Burden of Disease Diarrhoea Collaborators*.

The Effects of the iPlayClean Education Programme on Doping Attitudes and Susceptibility to use Banned Substances among High-Level Adolescent Athletes from the UK: A Cluster-Randomised Control Trial (2020)
Journal Article
Nicholls, A., Morley, D., Thompson, M. A., Huang, C., Abt, G., Rothwell, M., …Ntoumanis, N. (in press). The Effects of the iPlayClean Education Programme on Doping Attitudes and Susceptibility to use Banned Substances among High-Level Adolescent Athletes from the UK: A Cluster-Randomised Control Trial. International Journal of Drug Policy,

Background: This study examined the effects of the iPlayClean anti-doping intervention on attitudes towards doping and susceptibility, and whether delivery mode affected the results. Methods: A total of 1,081 high-level UK athletes (14-18 years old... Read More about The Effects of the iPlayClean Education Programme on Doping Attitudes and Susceptibility to use Banned Substances among High-Level Adolescent Athletes from the UK: A Cluster-Randomised Control Trial.

Prevalence and attributable health burden of chronic respiratory diseases, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017 (2020)
Journal Article
Soriano, J. B., Kendrick, P., Paulson, K., Gupta, V., Vos, T., GBD Chronic Respiratory Disease Collaborators, , & Soyiri, I. (2020). Prevalence and attributable health burden of chronic respiratory diseases, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017. The lancet. Respiratory medicine, 8(6), 585-596. https://doi.org/10.1016/S2213-2600%2820%2930105-3

Background Previous attempts to characterise the burden of chronic respiratory diseases have focused only on specific disease conditions, such as chronic obstructive pulmonary disease (COPD) or asthma. In this study, we aimed to characterise the bur... Read More about Prevalence and attributable health burden of chronic respiratory diseases, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017.

Quality of life changes with duration of chronic breathlessness: a random sample of community-dwelling people. (2020)
Journal Article
Currow, D. C., Chang, S., Grande, E. D., Ferreira, D. H., Kochovska, S., Kinchin PhD, I., …Ekstrom, M. (2020). Quality of life changes with duration of chronic breathlessness: a random sample of community-dwelling people. Journal of pain and symptom management, https://doi.org/10.1016/j.jpainsymman.2020.05.015

Introduction Chronic breathlessness is associated with poorer quality of life. This population study aimed to define dimensions of quality of life (QoL), and duration and dominant causes of breathlessness that most diminished QoL. Methods This... Read More about Quality of life changes with duration of chronic breathlessness: a random sample of community-dwelling people..

A randomised Phase II trial of carboplatin and gemcitabine ± vandetanib in first-line treatment of patients with advanced urothelial cell cancer not suitable to receive cisplatin (2020)
Journal Article
Jones, R., Crabb, S., Chester, J., Elliott, T., Huddart, R., Birtle, A., …Griffiths, G. (2020). A randomised Phase II trial of carboplatin and gemcitabine ± vandetanib in first-line treatment of patients with advanced urothelial cell cancer not suitable to receive cisplatin. BJU international, 126(2), 292-299. https://doi.org/10.1111/bju.15096

Objectives To assess the efficacy and tolerability of the dual epidermal growth factor receptor/vascular endothelial growth factor receptor inhibitor, vandetanib, in combination with carboplatin and gemcitabine in the first‐line treatment of patient... Read More about A randomised Phase II trial of carboplatin and gemcitabine ± vandetanib in first-line treatment of patients with advanced urothelial cell cancer not suitable to receive cisplatin.

Understanding usual care in randomised controlled trials of complex interventions: A multi-method approach (2020)
Journal Article
Evans, C. J., Yorganci, E., Evans, C. J., Johnson, H., Barclay, S., Murtagh, F. E., …Koffman, J. (2020). Understanding usual care in randomised controlled trials of complex interventions: A multi-method approach. Palliative medicine, https://doi.org/10.1177/0269216320905064

Background Evaluations of complex interventions compared to usual care provided in palliative care are increasing. Not describing usual care may affect the interpretation of an intervention’s effectiveness, yet how it can be described remains unclear... Read More about Understanding usual care in randomised controlled trials of complex interventions: A multi-method approach.

Considerations on equity in management of end-stage kidney disease in low- and middle-income countries (2020)
Journal Article
Van Biesen, W., Jha, V., Abu-Alfa, A. K., Andreoli, S. P., Ashuntantang, G., Bernieh, B., …Garcia Garcia, G. (2020). Considerations on equity in management of end-stage kidney disease in low- and middle-income countries. Kidney International Supplements, 10(1), e63-e71. https://doi.org/10.1016/j.kisu.2019.11.004

Achievement of equity in health requires development of a health system in which everyone has a fair opportunity to attain their full health potential. The current, large country-level variation in the reported incidence and prevalence of treated end... Read More about Considerations on equity in management of end-stage kidney disease in low- and middle-income countries.

Minimal clinically important differences in average, best, worst and current intensity and unpleasantness of chronic breathlessness (2020)
Journal Article
Ekström, M., Johnson, M. J., Huang, C., & Currow, D. C. (2020). Minimal clinically important differences in average, best, worst and current intensity and unpleasantness of chronic breathlessness. European respiratory journal, 55(5), https://doi.org/10.1183/13993003.02202-2019

Background: Chronic breathlessness has devastating consequences. The minimal clinically important difference (MCID) for current intensity has been estimated as 9mm on a 100mm visual analogue scale (VAS). We aimed to determine MCIDs for commonly used... Read More about Minimal clinically important differences in average, best, worst and current intensity and unpleasantness of chronic breathlessness.

Measuring universal health coverage based on an index of effective coverage of health services in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019 (2020)
Journal Article
Bakhtiari, A., Balachandran, A., Banach, M., Balassyano, S., Baig, A. A., Bakhshaei, M. H., …Murray, C. J. L. (2020). Measuring universal health coverage based on an index of effective coverage of health services in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019. Lancet, https://doi.org/10.1016/S0140-6736%2820%2930750-9

© 2020 Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license Background: Achieving universal health coverage (UHC) involves all people receiving the health services they need, of high quality, without experi... Read More about Measuring universal health coverage based on an index of effective coverage of health services in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019.

Information design for bowel cancer detection. The impact of using information visualization to help patients prepare for colonoscopy screening, using a booklet, a motion graphics and an App. (2019)
Journal Article
dos Santos Lonsdale, M., Ni, L., Gu, C., & Twiddy, M. (2019). Information design for bowel cancer detection. The impact of using information visualization to help patients prepare for colonoscopy screening, using a booklet, a motion graphics and an App. Information Design Journal, 25(2), 125-156. https://doi.org/10.1075/idj.25.2.01lon

Colorectal cancer is one of the most commonly occurring cancers in the world, and colonoscopy is the most sensitive procedure to detect it. Colonoscopy success depends on the quality of bowel preparation, but the way information is designed and commu... Read More about Information design for bowel cancer detection. The impact of using information visualization to help patients prepare for colonoscopy screening, using a booklet, a motion graphics and an App..