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All Outputs (60)

Development of a Core Outcome Set for the research and assessment of malignant bowel obstruction (2023)
Journal Article
Bravington, A., Obita, G., Baddeley, E., Johnson, M., Murtagh, F., Currow, D., …Boland, J. (2023). Development of a Core Outcome Set for the research and assessment of malignant bowel obstruction. PLoS ONE, 18(8), Article e0289501. https://doi.org/10.1371/journal.pone.0289501

Background: Malignant bowel obstruction is experienced by 15% of people with advanced cancer, preventing them from eating and drinking and causing pain, nausea and vomiting. Surgery is not always appropriate. Management options include tube or stent... Read More about Development of a Core Outcome Set for the research and assessment of malignant bowel obstruction.

Non-pharmacological interventions to manage psychological distress in patients living with cancer: a systematic review (2023)
Journal Article
Paley, C. A., Boland, J. W., Santarelli, M., Murtagh, F. E., Ziegler, L., & Chapman, E. J. (2023). Non-pharmacological interventions to manage psychological distress in patients living with cancer: a systematic review. BMC Palliative Care, 22(1), Article 88. https://doi.org/10.1186/s12904-023-01202-8

BACKGROUND: Psychological distress is common in patients with cancer; interfering with physical and psychological wellbeing, and hindering management of physical symptoms. Our aim was to systematically review published evidence on non-pharmacological... Read More about Non-pharmacological interventions to manage psychological distress in patients living with cancer: a systematic review.

Effects of Opioids on Immune and Endocrine Function in Patients with Cancer Pain (2023)
Journal Article
Bradley, A., & Boland, J. W. (2023). Effects of Opioids on Immune and Endocrine Function in Patients with Cancer Pain. Current Treatment Options in Oncology, 24(7), 867-879. https://doi.org/10.1007/s11864-023-01091-2

Opioids are an important treatment in managing cancer pain. Uncontrolled pain can be detrimental to function and quality of life. Common adverse effects of opioids such as sedation, constipation and nausea are well recognised, but opioid effects on t... Read More about Effects of Opioids on Immune and Endocrine Function in Patients with Cancer Pain.

High-quality phase 3 studies do not support the use of somatostatin analogues to reduce vomiting in malignant bowel obstruction (2023)
Journal Article
Boland, J. W., Boland, E. G., & Currow, D. C. (2023). High-quality phase 3 studies do not support the use of somatostatin analogues to reduce vomiting in malignant bowel obstruction. Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 31(4), Article 211. https://doi.org/10.1007/s00520-023-07669-8

Over a third of palliative medicine physicians meet burnout criteria: Results from a survey study during the COVID-19 pandemic (2023)
Journal Article
Boland, J. W., Kabir, M., Spilg, E. G., Webber, C., Bush, S. H., Murtagh, F., & Lawlor, P. G. (2023). Over a third of palliative medicine physicians meet burnout criteria: Results from a survey study during the COVID-19 pandemic. Palliative medicine, 37(3), 343-354. https://doi.org/10.1177/02692163231153067

Background: Palliative medicine physicians may be at higher risk of burnout due to increased stressors and compromised resilience during the COVID-19 pandemic. Burnout prevalence and factors influencing this among UK and Irish palliative medicine phy... Read More about Over a third of palliative medicine physicians meet burnout criteria: Results from a survey study during the COVID-19 pandemic.

A non-randomised controlled study to assess the effectiveness of a new proactive multidisciplinary care intervention for older people living with frailty (2023)
Journal Article
Murtagh, F. E., Okoeki, M., Ukoha-kalu, B. O., Khamis, A., Clark, J., Boland, J. W., …Johnson, M. J. (2023). A non-randomised controlled study to assess the effectiveness of a new proactive multidisciplinary care intervention for older people living with frailty. BMC Geriatrics, 23(1), Article 6. https://doi.org/10.1186/s12877-023-03727-2

Background Integrated care may improve outcomes for older people living with frailty. We aimed to assess the effectiveness of a new, anticipatory, multidisciplinary care service in improving the wellbeing and quality of life (QoL) of older people li... Read More about A non-randomised controlled study to assess the effectiveness of a new proactive multidisciplinary care intervention for older people living with frailty.

Development of a Core Outcome Set for the research and assessment of inoperable malignant bowel obstruction (2023)
Journal Article
Bravington, A., Obita, G., Baddeley, E., Johnson, M. J., Murtagh, F. E., Currow, D. C., …Boland, J. W. (2023). Development of a Core Outcome Set for the research and assessment of inoperable malignant bowel obstruction. PLoS ONE, 18(8), Article e0289501. https://doi.org/10.1371/journal.pone.0289501

BACKGROUND: Malignant bowel obstruction is experienced by 15% of people with advanced cancer, preventing them from eating and drinking and causing pain, nausea and vomiting. Surgery is not always appropriate. Management options include tube or stent... Read More about Development of a Core Outcome Set for the research and assessment of inoperable malignant bowel obstruction.

Experiences of a Novel Integrated Service for Older Adults at Risk of Frailty: A Qualitative Study (2023)
Journal Article
Wilson, I., Ukoha-kalu, B. O., Okoeki, M., Clark, J., Boland, J. W., Pask, S., …Murtagh, F. E. (2023). Experiences of a Novel Integrated Service for Older Adults at Risk of Frailty: A Qualitative Study. Journal of Patient Experience, 10, https://doi.org/10.1177/23743735231199827

The UK has a significant and growing population of older adults with frailty and complex healthcare needs, necessitating innovative care solutions. This study aimed to explore patients’ and carers’ experiences of a novel integrated service that was s... Read More about Experiences of a Novel Integrated Service for Older Adults at Risk of Frailty: A Qualitative Study.

Parental death: a systematic review of support experiences and needs of children and parent survivors (2022)
Journal Article
Wray, A., Pickwell-Smith, B., Greenley, S., Pask, S., Bamidele, O., Wright, B., …Boland, J. W. (2022). Parental death: a systematic review of support experiences and needs of children and parent survivors. BMJ supportive & palliative care, https://doi.org/10.1136/spcare-2022-003793

Background: Bereaved people need a supportive response from those around them. Knowing children's and surviving parents' needs following parental death is the first step to ensuring a supportive response. However, no systematic review has reported on... Read More about Parental death: a systematic review of support experiences and needs of children and parent survivors.

The range and suitability of outcome measures used in the assessment of palliative treatment for inoperable malignant bowel obstruction: A systematic review (2022)
Journal Article
Seddon, K., Bravington, A., Obita, G., Baddeley, E., Johnson, M. J., Murtagh, F. E., …Boland, J. W. (2022). The range and suitability of outcome measures used in the assessment of palliative treatment for inoperable malignant bowel obstruction: A systematic review. Palliative medicine, 36(9), 1336-1350. https://doi.org/10.1177/02692163221122352

Background: Malignant bowel obstruction, a complication of certain advanced cancers, causes severe symptoms which profoundly affect quality of life. Clinical management remains complex, and outcome assessment is inconsistent. Aim: To identify outc... Read More about The range and suitability of outcome measures used in the assessment of palliative treatment for inoperable malignant bowel obstruction: A systematic review.

Implementation lessons learnt when trialling palliative care interventions in the intensive care unit: relationships between determinants, implementation strategies, and models of delivery-a systematic review protocol (2022)
Journal Article
Meddick-Dyson, S. A., Boland, J. W., Pearson, M., Greenley, S., Gambe, R., Budding, J. R., & Murtagh, F. E. (2022). Implementation lessons learnt when trialling palliative care interventions in the intensive care unit: relationships between determinants, implementation strategies, and models of delivery-a systematic review protocol. Systematic reviews, 11(1), Article 186. https://doi.org/10.1186/s13643-022-02054-8

BACKGROUND: Heterogeneity amongst palliative care interventions in the intensive care unit (ICU) and their outcomes has meant that, even when found to be effective, translation of evidence into practice is hindered. Previous evidence reviews have sug... Read More about Implementation lessons learnt when trialling palliative care interventions in the intensive care unit: relationships between determinants, implementation strategies, and models of delivery-a systematic review protocol.

Improving the Detection, Assessment, Management and Prevention of Delirium in Hospices (the DAMPen-D study): protocol for a co-design and feasibility study of a flexible and scalable implementation strategy to deliver guideline-adherent delirium care (2022)
Journal Article
Pearson, M., Jackson, G., Jackson, C., Boland, J., Featherstone, I., Huang, C., …Johnson, M. (2022). Improving the Detection, Assessment, Management and Prevention of Delirium in Hospices (the DAMPen-D study): protocol for a co-design and feasibility study of a flexible and scalable implementation strategy to deliver guideline-adherent delirium care. BMJ open, 12(7), Article e060450. https://doi.org/10.1136/bmjopen-2021-060450

INTRODUCTION: Delirium is a complex condition in which altered mental state and cognition causes severe distress and poor clinical outcomes for patients and families, anxiety and stress for the health professionals and support staff providing care, a... Read More about Improving the Detection, Assessment, Management and Prevention of Delirium in Hospices (the DAMPen-D study): protocol for a co-design and feasibility study of a flexible and scalable implementation strategy to deliver guideline-adherent delirium care.

Symptom burden and lived experiences of patients, caregivers and healthcare professionals on the management of malignant bowel obstruction: A qualitative systematic review (2022)
Journal Article
Baddeley, E., Mann, M., Bravington, A., Johnson, M. J., Currow, D., Murtagh, F. E., …Noble, S. (in press). Symptom burden and lived experiences of patients, caregivers and healthcare professionals on the management of malignant bowel obstruction: A qualitative systematic review. Palliative medicine, https://doi.org/10.1177/02692163221081331

Background: Malignant bowel obstruction occurs in up to 50% of people with advanced ovarian and 15% of people with gastrointestinal cancers. Evaluation and comparison of interventions to manage symptoms are hampered by inconsistent evaluations of eff... Read More about Symptom burden and lived experiences of patients, caregivers and healthcare professionals on the management of malignant bowel obstruction: A qualitative systematic review.

Risk factors for delirium in adult patients receiving specialist palliative care: A systematic review and meta-analysis (2021)
Journal Article
Featherstone, I., Sheldon, T., Woodhouse, R., Boland, J. W., Hosie, A., Lawlor, P. G., …Johnson, M. (in press). Risk factors for delirium in adult patients receiving specialist palliative care: A systematic review and meta-analysis. Palliative medicine, https://doi.org/10.1177/02692163211065278

Background: Delirium is common and distressing for patients receiving palliative care. Interventions targetting modifiable risk factors in other settings have been shown to prevent delirium. Research on delirium risk factors in palliative care can in... Read More about Risk factors for delirium in adult patients receiving specialist palliative care: A systematic review and meta-analysis.

Implementing person-centred outcome measures (PCOMs) into routine palliative care: A protocol for a mixed-methods process evaluation of the RESOLVE PCOM Implementation Strategy (2021)
Journal Article
Bradshaw, A., Santarelli, M., Khamis, A. M., Sartain, K., Johnson, M., Boland, J., …Murtagh, F. E. (2021). Implementing person-centred outcome measures (PCOMs) into routine palliative care: A protocol for a mixed-methods process evaluation of the RESOLVE PCOM Implementation Strategy. BMJ open, 11(9), Article e051904. https://doi.org/10.1136/bmjopen-2021-051904

Introduction Person-centred outcome measures improve quality of care and patient outcomes but are used inconsistently in palliative care practice. To address this implementation gap, we developed the 'RESOLVE Implementation Strategy'. This protocol d... Read More about Implementing person-centred outcome measures (PCOMs) into routine palliative care: A protocol for a mixed-methods process evaluation of the RESOLVE PCOM Implementation Strategy.

Outcomes and measures of delirium interventional studies in palliative care to inform a core outcome set: A systematic review (2021)
Journal Article
Agar, M. R., Siddiqi, N., Hosie, A., Boland, J. W., Johnson, M. J., Featherstone, I., …Rose, L. (2021). Outcomes and measures of delirium interventional studies in palliative care to inform a core outcome set: A systematic review. Palliative medicine, 35(10), 1761-1775. https://doi.org/10.1177/02692163211040186

Background: Trials of interventions for delirium in various patient populations report disparate outcomes and measures but little is known about those used in palliative care trials. A core outcome set promotes consistency of outcome selection and me... Read More about Outcomes and measures of delirium interventional studies in palliative care to inform a core outcome set: A systematic review.

Clinical Predictors for Analgesic Response to Radiotherapy in Patients with Painful Bone Metastases (2021)
Journal Article
Habberstad, R., Frøseth, T. C. S., Aass, N., Bjerkeset, E., Abramova, T., Garcia-Alonso, E., …Klepstad, P. (2021). Clinical Predictors for Analgesic Response to Radiotherapy in Patients with Painful Bone Metastases. Journal of pain and symptom management, 62(4), 681-690. https://doi.org/10.1016/j.jpainsymman.2021.03.022

Background: Radiotherapy (RT) reduces pain in about 60% of patients with painful bone metastases, leaving many patients without clinical benefit. This study assesses predictors for RT effectiveness in patients with painful bone metastases. Materials... Read More about Clinical Predictors for Analgesic Response to Radiotherapy in Patients with Painful Bone Metastases.

Implementing person-centred outcome measures in palliative care: An exploratory qualitative study using Normalisation Process Theory to understand processes and context (2020)
Journal Article
Bradshaw, A., Santarelli, M., Mulderrig, M., Khamis, A., Sartain, K., Boland, J. W., …Murtagh, F. E. (in press). Implementing person-centred outcome measures in palliative care: An exploratory qualitative study using Normalisation Process Theory to understand processes and context. Palliative medicine, https://doi.org/10.1177/0269216320972049

© The Author(s) 2020. Background: Despite evidence demonstrating the utility of using Person-Centred Outcome Measures within palliative care settings, implementing them into routine practice is challenging. Most research has described barriers to, wi... Read More about Implementing person-centred outcome measures in palliative care: An exploratory qualitative study using Normalisation Process Theory to understand processes and context.

Development of a core outcome set to use in the research and assessment of malignant bowel obstruction: protocol for the RAMBO study (2020)
Journal Article
Baddeley, E., Bravington, A., Johnson, M., Currow, D., Murtagh, F. E., Boland, E., …Boland, J. (2020). Development of a core outcome set to use in the research and assessment of malignant bowel obstruction: protocol for the RAMBO study. BMJ open, 10(6), Article 039154. https://doi.org/10.1136/bmjopen-2020-039154

INTRODUCTION: Studies regarding the management of malignant bowel obstruction (MBO) report conflicting findings. This is partly due to different outcome measures being used to evaluate severity of MBO and the response to treatments. Furthermore, curr... Read More about Development of a core outcome set to use in the research and assessment of malignant bowel obstruction: protocol for the RAMBO study.