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Symptom management in people dying with COVID-19: multinational observational study (2022)
Journal Article
Oluyase, A. O., Bajwah, S., Sleeman, K. E., Walshe, C., Preston, N., Hocaoglu, M., …Higginson, I. J. (2022). Symptom management in people dying with COVID-19: multinational observational study. BMJ Supportive & Palliative Care, 12(4), 439-447. https://doi.org/10.1136/spcare-2022-003799

OBJECTIVES: To describe multinational prescribing practices by palliative care services for symptom management in patients dying with COVID-19 and the perceived effectiveness of medicines. METHODS: We surveyed specialist palliative care services, con... Read More about Symptom management in people dying with COVID-19: multinational observational study.

Implementation lessons learnt when trialling palliative care interventions in the intensive care unit: relationships between determinants, implementation strategies, and models of delivery-a systematic review protocol (2022)
Journal Article
Meddick-Dyson, S. A., Boland, J. W., Pearson, M., Greenley, S., Gambe, R., Budding, J. R., & Murtagh, F. E. (2022). Implementation lessons learnt when trialling palliative care interventions in the intensive care unit: relationships between determinants, implementation strategies, and models of delivery-a systematic review protocol. Systematic reviews, 11(1), Article 186. https://doi.org/10.1186/s13643-022-02054-8

BACKGROUND: Heterogeneity amongst palliative care interventions in the intensive care unit (ICU) and their outcomes has meant that, even when found to be effective, translation of evidence into practice is hindered. Previous evidence reviews have sug... Read More about Implementation lessons learnt when trialling palliative care interventions in the intensive care unit: relationships between determinants, implementation strategies, and models of delivery-a systematic review protocol.

Mixed-methods feasibility cluster randomised controlled trial of a paramedic-administered breathlessness management intervention for acute-on-chronic breathlessness (BREATHE): study findings (2022)
Journal Article
Hutchinson, A., Allgar, V., Cohen, J., Currow, D. C., Griffin, S., Hart, S., …Johnson, M. J. (2022). Mixed-methods feasibility cluster randomised controlled trial of a paramedic-administered breathlessness management intervention for acute-on-chronic breathlessness (BREATHE): study findings. ERJ Open Research, 8(4), Article 00257-2022. https://doi.org/10.1183/23120541.00257-2022

Introduction: One-fifth of emergency department presentations by ambulance are due to acute-on-chronic breathlessness. We explored the feasibility of an evaluation-phase, cluster randomised controlled trial (cRCT) of the effectiveness and cost-effect... Read More about Mixed-methods feasibility cluster randomised controlled trial of a paramedic-administered breathlessness management intervention for acute-on-chronic breathlessness (BREATHE): study findings.

Evaluation of a complex intervention for prisoners with common mental health problems, near to and after release: The Engager randomised controlled trial (2022)
Journal Article
Byng, R., Kirkpatrick, T., Lennox, C., Warren, F., Anderson, R., Brand, S., …Shaw, J. (2023). Evaluation of a complex intervention for prisoners with common mental health problems, near to and after release: The Engager randomised controlled trial. British Journal of Psychiatry, 222(1), 18-26. https://doi.org/10.1192/bjp.2022.93

Background Many male prisoners have significant mental health problems, including anxiety and depression. High proportions struggle with homelessness and substance misuse. Aims This study aims to evaluate whether the Engager intervention improves men... Read More about Evaluation of a complex intervention for prisoners with common mental health problems, near to and after release: The Engager randomised controlled trial.

Evaluating a web-based computer-tailored physical activity intervention for those living with and beyond lung cancer (ExerciseGuide UK): protocol for a single group feasibility and acceptability study (2022)
Journal Article
Curry, J., Lind, M., Short, C. E., Vandelanotte, C., Evans, H. E., Pearson, M., & Forbes, C. C. (2022). Evaluating a web-based computer-tailored physical activity intervention for those living with and beyond lung cancer (ExerciseGuide UK): protocol for a single group feasibility and acceptability study. Pilot and Feasibility Studies, 8(1), Article 182. https://doi.org/10.1186/s40814-022-01129-6

Background: Lung cancer is the leading cause of cancer-related death globally. Physical activity and exercise provide unequivocal benefits to those living with and beyond lung cancer. However, few of those living with and beyond cancer meet the natio... Read More about Evaluating a web-based computer-tailored physical activity intervention for those living with and beyond lung cancer (ExerciseGuide UK): protocol for a single group feasibility and acceptability study.

The association between socioeconomic position and the symptoms and concerns of hospital inpatients seen by specialist palliative care: Analysis of routinely collected patient data (2022)
Journal Article
Davies, J. M., Sleeman, K. E., Ramsenthaler, C., Prentice, W., Maddocks, M., & Murtagh, F. E. (2022). The association between socioeconomic position and the symptoms and concerns of hospital inpatients seen by specialist palliative care: Analysis of routinely collected patient data. Palliative medicine, https://doi.org/10.1177/02692163221115331

Background: Understanding how socioeconomic position influences the symptoms and concerns of patients approaching the end of life is important for planning more equitable care. Data on this relationship is lacking, particularly for patients with non-... Read More about The association between socioeconomic position and the symptoms and concerns of hospital inpatients seen by specialist palliative care: Analysis of routinely collected patient data.

Inoperable malignant bowel obstruction: palliative interventions outcomes-mixed-methods systematic review (2022)
Journal Article
Patterson, M., Greenley, S., Ma, Y., Bullock, A., Curry, J., Smithson, J., …Johnson, M. J. (2022). Inoperable malignant bowel obstruction: palliative interventions outcomes-mixed-methods systematic review. BMJ supportive & palliative care, Article 003492. https://doi.org/10.1136/bmjspcare-2021-003492

Background: Parenteral nutrition (PN) and palliative venting gastrostomies (PVG) are two interventions used clinically to manage inoperable malignant bowel obstruction (MBO); however, little is known about their role in clinical and quality-of-life o... Read More about Inoperable malignant bowel obstruction: palliative interventions outcomes-mixed-methods systematic review.

Improving the Detection, Assessment, Management and Prevention of Delirium in Hospices (the DAMPen-D study): protocol for a co-design and feasibility study of a flexible and scalable implementation strategy to deliver guideline-adherent delirium care (2022)
Journal Article
Pearson, M., Jackson, G., Jackson, C., Boland, J., Featherstone, I., Huang, C., …Johnson, M. (2022). Improving the Detection, Assessment, Management and Prevention of Delirium in Hospices (the DAMPen-D study): protocol for a co-design and feasibility study of a flexible and scalable implementation strategy to deliver guideline-adherent delirium care. BMJ open, 12(7), Article e060450. https://doi.org/10.1136/bmjopen-2021-060450

INTRODUCTION: Delirium is a complex condition in which altered mental state and cognition causes severe distress and poor clinical outcomes for patients and families, anxiety and stress for the health professionals and support staff providing care, a... Read More about Improving the Detection, Assessment, Management and Prevention of Delirium in Hospices (the DAMPen-D study): protocol for a co-design and feasibility study of a flexible and scalable implementation strategy to deliver guideline-adherent delirium care.

Why do acute healthcare staff engage in unprofessional behaviours towards each other and how can these behaviours be reduced? A realist review protocol (2022)
Journal Article
Maben, J., Aunger, J., Abrams, R., Pearson, M., Wright, J., Westbrook, J., …Jones, A. (2022). Why do acute healthcare staff engage in unprofessional behaviours towards each other and how can these behaviours be reduced? A realist review protocol. BMJ open, 12(7), Article e061771. https://doi.org/10.1136/bmjopen-2022-061771

INTRODUCTION: Unprofessional behaviours encompass many behaviours including bullying, harassment and microaggressions. These behaviours between healthcare staff are problematic; they affect people's ability to work, to feel psychologically safe at wo... Read More about Why do acute healthcare staff engage in unprofessional behaviours towards each other and how can these behaviours be reduced? A realist review protocol.

Interrogating intervention delivery and participants’ emotional states to improve engagement and implementation: A realist informed multiple case study evaluation of Engager (2022)
Journal Article
Weston, L., Rybczynska-Bunt, S., Quinn, C., Lennox, C., Maguire, M., Pearson, M., …Byng, R. (2022). Interrogating intervention delivery and participants’ emotional states to improve engagement and implementation: A realist informed multiple case study evaluation of Engager. PLoS ONE, 17(7 July), Article e0270691. https://doi.org/10.1371/journal.pone.0270691

Background ‘Engager’ is an innovative ‘through-the-gate’ complex care intervention for male prison-leavers with common mental health problems. In parallel to the randomised-controlled trial of Engager (Trial registration number: ISRCTN11707331), a se... Read More about Interrogating intervention delivery and participants’ emotional states to improve engagement and implementation: A realist informed multiple case study evaluation of Engager.

The most important components of out-of-hours community care for patients at the end of life: A Delphi study of healthcare professionals’ and patient and family carers’ perspectives (2022)
Journal Article
Goodrich, J., Tutt, L., Firth, A. M., Evans, C. J., Murtagh, F. E., & Harding, R. (2022). The most important components of out-of-hours community care for patients at the end of life: A Delphi study of healthcare professionals’ and patient and family carers’ perspectives. Palliative medicine, https://doi.org/10.1177/02692163221106284

Background: Community services for palliative patients outside normal working hours are variable and the best evidence-based models of care have not been determined. Aim: To establish expert consensus on the most important components of out-of-hours... Read More about The most important components of out-of-hours community care for patients at the end of life: A Delphi study of healthcare professionals’ and patient and family carers’ perspectives.

Le mystère des portraits de Robespierre aux rayures (2022)
Digital Artefact
Gilchrist, M. (2022). Le mystère des portraits de Robespierre aux rayures. [Webpage text with illustrations]

The portrait of Robespierre in a striped coat (Musée Carnavalet P.729) is probably his most popular and most reproduced portrait in modern times. However, in researching his iconography, I was surprised to find it was not in circulation during his li... Read More about Le mystère des portraits de Robespierre aux rayures.

Robespierre au cinéma anglophone (2022)
Digital Artefact
Gilchrist, M. (2022). Robespierre au cinéma anglophone. [Webpage text with illustrations]

Anglophone cinema and television has generally presented a hostile image of Robespierre. It is rooted in propaganda of the Pitt era but was expanded and elaborated in the 19C by Carlyle, Lamartine, Marie Tussaud, and a number of historical novels and... Read More about Robespierre au cinéma anglophone.

Symptom Control and Survival for People Severely ill With COVID: A Multicentre Cohort Study (CovPall-Symptom) (2022)
Journal Article
Higginson, I. J., Hocaoglu, M., Fraser, L. K., Maddocks, M., Sleeman, K. E., Oluyase, A. O., …On behalf of theCovPall study team. (2022). Symptom Control and Survival for People Severely ill With COVID: A Multicentre Cohort Study (CovPall-Symptom). Journal of pain and symptom management, 64(4), 377-390. https://doi.org/10.1016/j.jpainsymman.2022.06.009

Context: Evidence of symptom control outcomes in severe COVID is scant. Objectives: To determine changes in symptoms among people severely ill or dying with COVID supported by palliative care, and associations with treatments and survival. Methods: M... Read More about Symptom Control and Survival for People Severely ill With COVID: A Multicentre Cohort Study (CovPall-Symptom).

Substituting bouts of sedentary behavior with physical activity: adopting positive lifestyle choices in people with a history of cancer (2022)
Journal Article
Ingle, L., Ruilova, S., Cui, Y., DeClercq, V., Sweeney, E., Yu, Z. M., & Forbes, C. C. (2022). Substituting bouts of sedentary behavior with physical activity: adopting positive lifestyle choices in people with a history of cancer. Cancer Causes and Control, https://doi.org/10.1007/s10552-022-01592-9

Purpose: To determine in people with a history of cancer, whether substituting sitting time with other daily activities (i.e., sleeping, walking, moderate and vigorous physical activity) was associated with changes in waist circumference (WC), an imp... Read More about Substituting bouts of sedentary behavior with physical activity: adopting positive lifestyle choices in people with a history of cancer.

Comparing recalled versus experienced symptoms of breathlessness ratings: An ecological assessment study using mobile phone technology (2022)
Journal Article
Sandberg, J., Sundh, J., Anderberg, P., Currow, D. C., Johnson, M., Lansing, R., & Ekström, M. (2022). Comparing recalled versus experienced symptoms of breathlessness ratings: An ecological assessment study using mobile phone technology. Respirology : official journal of the Asian Pacific Society of Respirology, https://doi.org/10.1111/resp.14313

Background and objective: Recall of breathlessness is important for clinical care but might differ from the experienced (momentary) symptoms. This study aimed to characterize the relationship between momentary breathlessness ratings and the recall of... Read More about Comparing recalled versus experienced symptoms of breathlessness ratings: An ecological assessment study using mobile phone technology.

Face and content validity, acceptability, feasibility, and implementability of a novel outcome measure for children with life-limiting or life-threatening illness in three sub-Saharan African countries (2022)
Journal Article
Namisango, E., Bristowe, K., Murtagh, F. E., Downing, J., Powell, R. A., Atieno, M., …Harding, R. (2022). Face and content validity, acceptability, feasibility, and implementability of a novel outcome measure for children with life-limiting or life-threatening illness in three sub-Saharan African countries. Palliative medicine, 36(7), 1140-1153. https://doi.org/10.1177/02692163221099583

Background: The Children’s Palliative Care Outcome Scale (C-POS) is the first measure developed for children with life-limiting and -threatening illness. It is essential to determine whether the measure addresses what matters to children, and if they... Read More about Face and content validity, acceptability, feasibility, and implementability of a novel outcome measure for children with life-limiting or life-threatening illness in three sub-Saharan African countries.

Thinking About the Future, Symptom Control and Other Aspects of Palliative Care in Advanced CKD (2022)
Book Chapter
Murtagh, F. E., Wilson, J., & Davison, S. N. (2022). Thinking About the Future, Symptom Control and Other Aspects of Palliative Care in Advanced CKD. In M. Harber (Ed.), Primer on Nephrology (1163-1174). Cham: Springer. https://doi.org/10.1007/978-3-030-76419-7_68

Palliative and supportive care have always been important for those with advanced CKD, but – until recently – there has been little research or evidence to inform best care. This is changing rapidly. This chapter draws on recent evidence to provide a... Read More about Thinking About the Future, Symptom Control and Other Aspects of Palliative Care in Advanced CKD.

Tumour-Associated Tissue Factor (TF)-mRNA Is A Precursor for Rapid TF-Microvesicle Release and A Potential Predictive Marker for the Risk of Pulmonary Embolism (PE) in Gastrointestinal Cancer Patients (2022)
Journal Article
Ettelaie, C., Benelhaj, N., Featherby, S., Haque, F., Johnson, M., Cooke, J., & Maraveyas, A. (2022). Tumour-Associated Tissue Factor (TF)-mRNA Is A Precursor for Rapid TF-Microvesicle Release and A Potential Predictive Marker for the Risk of Pulmonary Embolism (PE) in Gastrointestinal Cancer Patients. Journal of Biotechnology and Biomedicine, 5(2), 78-93. https://doi.org/10.26502/jbb.2642-280050

Predicting which cancer patients are at risk of thrombosis remains a key challenge to effective thromboprophylaxis. This study was based on the hypothesis that the rapid release of TF-containing MV occurs in cancer cells that possess high levels of T... Read More about Tumour-Associated Tissue Factor (TF)-mRNA Is A Precursor for Rapid TF-Microvesicle Release and A Potential Predictive Marker for the Risk of Pulmonary Embolism (PE) in Gastrointestinal Cancer Patients.