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All Outputs (134)

What are the anticipated benefits, risks, barriers, and facilitators to implementing person-centred outcome measures into routine care for children and young people with life-limiting and life-threatening conditions? A qualitative interview study with key stakeholders (2024)
Journal Article
May Scott, H., Coombes, L., Braybrook, D., Harðardóttir, D., Roach, A., Bristowe, K., …On Behalf Of C-POS. (in press). What are the anticipated benefits, risks, barriers, and facilitators to implementing person-centred outcome measures into routine care for children and young people with life-limiting and life-threatening conditions? A qualitative interview study with key stakeholders. Palliative medicine, https://doi.org/10.1177/02692163241234797

Background: There is a growing evidence-base underpinning implementation of person-centred outcome measures into adult palliative care. However evidence on how best to achieve this with children facing life-threatening and life-limiting conditions i... Read More about What are the anticipated benefits, risks, barriers, and facilitators to implementing person-centred outcome measures into routine care for children and young people with life-limiting and life-threatening conditions? A qualitative interview study with key stakeholders.

Creating more comparable cohorts in observational palliative care studies: a proposed framework to improve applicability and replicability of research (2024)
Journal Article
Kochovska, S., Murtagh, F. E., Agar, M., Phillips, J. L., Dudgeon, D., Lujic, S., …Currow, D. C. (in press). Creating more comparable cohorts in observational palliative care studies: a proposed framework to improve applicability and replicability of research. Palliative medicine, https://doi.org/10.1177/02692163241234227

Background Palliative care is characterised by heterogeneous patient and caregiver populations who are provided care in different health systems and a research base including a large proportion of observational, mostly retrospective studies. The inh... Read More about Creating more comparable cohorts in observational palliative care studies: a proposed framework to improve applicability and replicability of research.

‘My life is a mess but I cope’: An analysis of the language children and young people use to describe their own life-limiting or life-threatening condition (2024)
Journal Article
Bristowe, K., Braybrook, D., Scott, H. M., Coombes, L., Harðardóttir, D., Roach, A., …Harding, R. (2024). ‘My life is a mess but I cope’: An analysis of the language children and young people use to describe their own life-limiting or life-threatening condition. Palliative medicine, https://doi.org/10.1177/02692163241233977

Background: Children and young people with life-limiting and life-threatening conditions have multidimensional needs and heterogenous cognitive and communicative abilities. There is limited evidence to support clinicians to tailor their communication... Read More about ‘My life is a mess but I cope’: An analysis of the language children and young people use to describe their own life-limiting or life-threatening condition.

Advance care planning for patients with end-stage kidney disease on dialysis: narrative review of the current evidence, and future considerations (2024)
Journal Article
Adenwalla, S. F., O’Halloran, P., Faull, C., Murtagh, F. E. M., & Graham-Brown, M. P. M. (2024). Advance care planning for patients with end-stage kidney disease on dialysis: narrative review of the current evidence, and future considerations. Journal of Nephrology, https://doi.org/10.1007/s40620-023-01841-3

Patients with end-stage kidney disease (ESKD) have a high symptom-burden and high rates of morbidity and mortality. Despite this, evidence has shown that this patient group does not have timely discussions to plan for deterioration and death, and at... Read More about Advance care planning for patients with end-stage kidney disease on dialysis: narrative review of the current evidence, and future considerations.

A casemix classification for those receiving specialist palliative care during their last year of life across England: the C-CHANGE research programme (2023)
Journal Article
Murtagh, F. E., Guo, P., Firth, A., Yip, K. M., Ramsenthaler, C., Douiri, A., …Higginson, I. J. (2023). A casemix classification for those receiving specialist palliative care during their last year of life across England: the C-CHANGE research programme. Programme Grants for Applied Research, 11(7), https://doi.org/10.3310/plrp4875

Abstract Background The hospice movement has provided an excellent model of specialist palliative care for those with advanced illness approaching the end of life. However, there are marked inequities in provision of this care, and major geographic... Read More about A casemix classification for those receiving specialist palliative care during their last year of life across England: the C-CHANGE research programme.

Implementing patient-centred outcome measures in palliative care clinical practice for adults (IMPCOM): Protocol for an update systematic review of facilitators and barriers (2023)
Journal Article
Antunes, B., Barclay, S., Kuhn, I., Eagar, K., Bausewein, C., Murtagh, F., …Shokraneh, F. (2023). Implementing patient-centred outcome measures in palliative care clinical practice for adults (IMPCOM): Protocol for an update systematic review of facilitators and barriers. F1000Research, 12, Article 224. https://doi.org/10.12688/f1000research.131479.2

Background: Despite the development of patient-centred or patient-reported outcome measures (PCOMs or PROMs) in palliative and end-of-life care over recent years, their routine use in practice faces continuing challenges. Objective: To update a highl... Read More about Implementing patient-centred outcome measures in palliative care clinical practice for adults (IMPCOM): Protocol for an update systematic review of facilitators and barriers.

Development of a Core Outcome Set for the research and assessment of malignant bowel obstruction (2023)
Journal Article
Bravington, A., Obita, G., Baddeley, E., Johnson, M., Murtagh, F., Currow, D., …Boland, J. (2023). Development of a Core Outcome Set for the research and assessment of malignant bowel obstruction. PLoS ONE, 18(8), Article e0289501. https://doi.org/10.1371/journal.pone.0289501

Background: Malignant bowel obstruction is experienced by 15% of people with advanced cancer, preventing them from eating and drinking and causing pain, nausea and vomiting. Surgery is not always appropriate. Management options include tube or stent... Read More about Development of a Core Outcome Set for the research and assessment of malignant bowel obstruction.

Regional perspectives on the coordination and delivery of paediatric end-of-life care in the UK: a qualitative study (2023)
Journal Article
Papworth, A., Hackett, J., Beresford, B., Murtagh, F., Weatherly, H., Hinde, S., …Fraser, L. K. (2023). Regional perspectives on the coordination and delivery of paediatric end-of-life care in the UK: a qualitative study. BMC Palliative Care, 22(1), Article 117. https://doi.org/10.1186/s12904-023-01238-w

Background: Provision of and access to paediatric end-of-life care is inequitable, but previous research on this area has focused on perspectives of health professionals in specific settings or children with specific conditions. This qualitative stud... Read More about Regional perspectives on the coordination and delivery of paediatric end-of-life care in the UK: a qualitative study.

Referral Criteria to Specialist Palliative Care for People with Advanced Chronic Kidney Disease: A Systematic Review (2023)
Journal Article
Collins, A., Hui, D., Davison, S. N., Ducharlet, K., Murtagh, F., Chang, Y. K., & Philip, J. (2023). Referral Criteria to Specialist Palliative Care for People with Advanced Chronic Kidney Disease: A Systematic Review. Journal of pain and symptom management, 66(5), 541-550.e1. https://doi.org/10.1016/j.jpainsymman.2023.07.013

Context: People with advanced chronic kidney disease (CKD) have significant morbidity, yet for many, access to palliative care occurs late, if at all. Objectives: This study sought to examine criteria for referral to specialist palliative care for ad... Read More about Referral Criteria to Specialist Palliative Care for People with Advanced Chronic Kidney Disease: A Systematic Review.

Non-pharmacological interventions to manage psychological distress in patients living with cancer: a systematic review (2023)
Journal Article
Paley, C. A., Boland, J. W., Santarelli, M., Murtagh, F. E., Ziegler, L., & Chapman, E. J. (2023). Non-pharmacological interventions to manage psychological distress in patients living with cancer: a systematic review. BMC Palliative Care, 22(1), Article 88. https://doi.org/10.1186/s12904-023-01202-8

BACKGROUND: Psychological distress is common in patients with cancer; interfering with physical and psychological wellbeing, and hindering management of physical symptoms. Our aim was to systematically review published evidence on non-pharmacological... Read More about Non-pharmacological interventions to manage psychological distress in patients living with cancer: a systematic review.

Implementation of child-centred outcome measures in routine paediatric healthcare practice: a systematic review (2023)
Journal Article
Scott, H. M., Braybrook, D., Harðardóttir, D., Ellis-Smith, C., Harding, R., Anderson, A., …Whiting, M. (2023). Implementation of child-centred outcome measures in routine paediatric healthcare practice: a systematic review. Health and quality of life outcomes, 21(1), Article 63. https://doi.org/10.1186/s12955-023-02143-9

Background: Person-centred outcome measures (PCOMs) are commonly used in routine adult healthcare to measure and improve outcomes, but less attention has been paid to PCOMs in children’s services. The aim of this systematic review is to identify and... Read More about Implementation of child-centred outcome measures in routine paediatric healthcare practice: a systematic review.

Design and Administration of Patient-Centred Outcome Measures: The Perspectives of Children and Young People with Life-Limiting or Life-Threatening Conditions and Their Family Members (2023)
Journal Article
Coombes, L., Harðardóttir, D., Braybrook, D., Roach, A., Scott, H., Bristowe, K., …Harding, R. (in press). Design and Administration of Patient-Centred Outcome Measures: The Perspectives of Children and Young People with Life-Limiting or Life-Threatening Conditions and Their Family Members. Patient, https://doi.org/10.1007/s40271-023-00627-w

Background: Self-reported health data from children with life-limiting conditions is rarely collected. To improve acceptability and feasibility of child and family-centred outcome measures for children, they need to be designed in a way that reflects... Read More about Design and Administration of Patient-Centred Outcome Measures: The Perspectives of Children and Young People with Life-Limiting or Life-Threatening Conditions and Their Family Members.

Towards optimal use of antithrombotic therapy of people with cancer at the end of life: A research protocol for the development and implementation of the SERENITY shared decision support tool (2023)
Journal Article
Goedegebuur, J., Abbel, D., Accassat, S., Achterberg, W. P., Akbari, A., Arfuch, V. M., …Noble, S. I. (2023). Towards optimal use of antithrombotic therapy of people with cancer at the end of life: A research protocol for the development and implementation of the SERENITY shared decision support tool. Thrombosis Research, 228, 54-60. https://doi.org/10.1016/j.thromres.2023.05.008

BACKGROUND: Even though antithrombotic therapy has probably little or even negative effects on the well-being of people with cancer during their last year of life, deprescribing antithrombotic therapy at the end of life is rare in practice. It is oft... Read More about Towards optimal use of antithrombotic therapy of people with cancer at the end of life: A research protocol for the development and implementation of the SERENITY shared decision support tool.

Deaths at home, area-based deprivation and the effect of the Covid-19 pandemic: An analysis of mortality data across four nations (2023)
Journal Article
Leniz, J., Davies, J. M., Bone, A. E., Hocaoglu, M., Verne, J., Barclay, S., …Sleeman, K. E. (2023). Deaths at home, area-based deprivation and the effect of the Covid-19 pandemic: An analysis of mortality data across four nations. Palliative medicine, https://doi.org/10.1177/02692163231167212

Background: The number and proportion of home deaths in the UK increased during the Covid-19 pandemic. It is not known whether these changes were experienced disproportionately by people from different socioeconomic groups. Aim: To examine the associ... Read More about Deaths at home, area-based deprivation and the effect of the Covid-19 pandemic: An analysis of mortality data across four nations.

The roles and experiences of informal carers providing care to people with advanced cancer in Africa—A systematic review and critical interpretive analysis (2023)
Journal Article
Gambe, R. G., Clark, J., Meddick-Dyson, S. A., Ukoha-Kalu, B. O., Nyaaba, G. N., & Murtagh, F. E. (2023). The roles and experiences of informal carers providing care to people with advanced cancer in Africa—A systematic review and critical interpretive analysis. PLOS Global Public Health, 3(4), Article e0001785. https://doi.org/10.1371/journal.pgph.0001785

There is an increasing prevalence of cancer in Africa with approximately 80% of cancers diagnosed at an advanced stage. High out-of-pocket healthcare costs and overstretched health systems lead to heavy reliance on informal carers for cancer care. Th... Read More about The roles and experiences of informal carers providing care to people with advanced cancer in Africa—A systematic review and critical interpretive analysis.

Spiritual, religious, and existential concerns of children and young people with life-limiting and life-threatening conditions: A qualitative interview study (2023)
Journal Article
Scott, H. M., Coombes, L., Braybrook, D., Roach, A., Harðardóttir, D., Bristowe, K., …Harding, R. (2023). Spiritual, religious, and existential concerns of children and young people with life-limiting and life-threatening conditions: A qualitative interview study. Palliative medicine, https://doi.org/10.1177/02692163231165101

Background: Despite being a core domain of palliative care, primary data on spiritual and existential concerns has rarely been collected among children with life-limiting and life-threatening conditions and their families. Existing evidence has tende... Read More about Spiritual, religious, and existential concerns of children and young people with life-limiting and life-threatening conditions: A qualitative interview study.

Spiritual, religious, and existential concerns of children and young people with life-limiting and life-threatening conditions: A qualitative interview study (2023)
Journal Article
Scott, H. M., Coombes, L., Braybrook, D., Roach, A., Harðardóttir, D., Bristowe, K., …Harding, R. (2023). Spiritual, religious, and existential concerns of children and young people with life-limiting and life-threatening conditions: A qualitative interview study. Palliative medicine, 37(6), 856-865. https://doi.org/10.1177/02692163231165101

Background: Despite being a core domain of palliative care, primary data on spiritual and existential concerns has rarely been collected among children with life-limiting and life-threatening conditions and their families. Existing evidence has tende... Read More about Spiritual, religious, and existential concerns of children and young people with life-limiting and life-threatening conditions: A qualitative interview study.

Adaptation and multicentre validation of a patient-centred outcome scale for people severely ill with COVID (IPOS-COV) (2023)
Journal Article
Hocaoglu, M. B., Murtagh, F. E., Walshe, C., Chambers, R. L., Maddocks, M., Sleeman, K. E., …the CovPall study team. (2023). Adaptation and multicentre validation of a patient-centred outcome scale for people severely ill with COVID (IPOS-COV). Health and quality of life outcomes, 21(1), Article 29. https://doi.org/10.1186/s12955-023-02102-4

Background: Patient-centred measures to capture symptoms and concerns have rarely been reported in severe COVID. We adapted and tested the measurement properties of the proxy version of the Integrated Palliative care Outcome Scale–IPOS-COV for severe... Read More about Adaptation and multicentre validation of a patient-centred outcome scale for people severely ill with COVID (IPOS-COV).

Adaptation and multicentre validation of a patient-centred outcome scale for people severely ill with COVID (IPOS-COV) (2023)
Journal Article
Hocaoglu, M. B., Murtagh, F. E., Walshe, C., Chambers, R. L., Maddocks, M., Sleeman, K. E., …Higginson, I. J. (2023). Adaptation and multicentre validation of a patient-centred outcome scale for people severely ill with COVID (IPOS-COV). Health and quality of life outcomes, 21(1), Article 29. https://doi.org/10.1186/s12955-023-02102-4

Background: Patient-centred measures to capture symptoms and concerns have rarely been reported in severe COVID. We adapted and tested the measurement properties of the proxy version of the Integrated Palliative care Outcome Scale–IPOS-COV for severe... Read More about Adaptation and multicentre validation of a patient-centred outcome scale for people severely ill with COVID (IPOS-COV).

How is community based ‘out-of-hours’ care provided to patients with advanced illness near the end of life: A systematic review of care provision (2023)
Journal Article
Firth, A. M., Lin, C. P., Yi, D. H., Goodrich, J., Gaczkowska, I., Waite, F., …Evans, C. J. (2023). How is community based ‘out-of-hours’ care provided to patients with advanced illness near the end of life: A systematic review of care provision. Palliative medicine, 37(3), 310-328. https://doi.org/10.1177/02692163231154760

Background: Deaths in the community are increasing. However, community palliative care out-of-hours is variable. We lack detailed understanding of how care is provided out-of-hours and the associated outcomes. Aim: To review systematically the compon... Read More about How is community based ‘out-of-hours’ care provided to patients with advanced illness near the end of life: A systematic review of care provision.