Skip to main content

Research Repository

Advanced Search

All Outputs (135)

Assessing mechanical function of the zygomatic region in macaques: validation and sensitivity testing of finite element models (2006)
Journal Article
Kupczik, K., Dobson, C. A., Fagan, M. J., Crompton, R. H., Oxnard, C. E., & O'Higgins, P. (2007). Assessing mechanical function of the zygomatic region in macaques: validation and sensitivity testing of finite element models. Journal of anatomy, 210(1), 41-53. https://doi.org/10.1111/j.1469-7580.2006.00662.x

Crucial to the interpretation of the results of any finite element analysis of a skeletal system is a test of the validity of the results and an assessment of the sensitivity of the model parameters. We have therefore developed finite element models... Read More about Assessing mechanical function of the zygomatic region in macaques: validation and sensitivity testing of finite element models.

Three dimensional stereolithography models of cancellous bone structures from μCT data: Testing and validation of finite element results (2006)
Journal Article
Dobson, C. A., Sisias, G., Phillips, R., Langton, C. M., & Fagan, M. J. (2006). Three dimensional stereolithography models of cancellous bone structures from μCT data: Testing and validation of finite element results. Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine, 220(3), 481-484. https://doi.org/10.1243/09544119H00405

Stereolithography (STL) models of complex cancellous bone structures have been produced from three-dimensional micro-computed tomography data sets of human cancellous bone histological samples from four skeletal sites. The STL models have been mechan... Read More about Three dimensional stereolithography models of cancellous bone structures from μCT data: Testing and validation of finite element results.

A Comparative Study of Aortic Wall Stress Using Finite Element Analysis for Ruptured and Non-ruptured Abdominal Aortic Aneurysms*1 (2004)
Journal Article
VENKATASUBRAMANIAM, A., FAGAN, M., MEHTA, T., MYLANKAL, K., RAY, B., KUHAN, G., …MCCOLLUM, P. (2004). A Comparative Study of Aortic Wall Stress Using Finite Element Analysis for Ruptured and Non-ruptured Abdominal Aortic Aneurysms*1. European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery, 28(2), 168-176. https://doi.org/10.1016/S1078-5884%2804%2900178-9

Background. The decision to repair an asymptomatic abdominal aortic aneurysm (AAA) is currently based on diameter (greater than or equal to 5.5 cm) alone. However, aneurysms less than 5.5 cm do rupture while some reach greater than 5.5 cm without rup... Read More about A Comparative Study of Aortic Wall Stress Using Finite Element Analysis for Ruptured and Non-ruptured Abdominal Aortic Aneurysms*1.

A comparative study of aortic wall stress using finite element analysis for ruptured and non-ruptured abdominal aortic aneurysms (2004)
Journal Article
Venkatasubramaniam, A. K., Fagan, M. J., Mehta, T., Mylankal, K. J., Ray, B., Kuhan, G., …McCollum, P. T. (2004). A comparative study of aortic wall stress using finite element analysis for ruptured and non-ruptured abdominal aortic aneurysms. European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery, 28(2), 168-176. https://doi.org/10.1016/j.ejvs.2004.03.029

Background. The decision to repair an asymptomatic abdominal aortic aneurysm (AAA) is currently based on diameter (≥5.5 cm) alone. However, aneurysms less than 5.5 cm do rupture while some reach greater than 5.5 cm without rupturing. Hence the need t... Read More about A comparative study of aortic wall stress using finite element analysis for ruptured and non-ruptured abdominal aortic aneurysms.

Stereo visualization of 3D trabecular bone structures produced by bone remodelling simulation (2003)
Journal Article
Phillips, R., Grunchec, J. A., Ward, J. W., Fagan, M. J., Dobson, C. A., Langton, C. M., & Sisias, G. (2003). Stereo visualization of 3D trabecular bone structures produced by bone remodelling simulation. Studies in health technology and informatics, 94, 258-264. https://doi.org/10.3233/978-1-60750-938-7-258

Adult human bone is constantly being renewed by a process known as remodelling. For cancellous bone this renewal process occurs at the interface between bone and marrow where bone is depleted by osteoclasts and rebuilt by osteoblasts. This remodellin... Read More about Stereo visualization of 3D trabecular bone structures produced by bone remodelling simulation.

Patient-specific spine models. Part 1: Finite element analysis of the lumbar intervertebral disc—a material sensitivity study (2002)
Journal Article
Fagan, M. J., Julian, S., Siddall, D. J., & Mohsen, A. M. (2002). Patient-specific spine models. Part 1: Finite element analysis of the lumbar intervertebral disc—a material sensitivity study. Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine, 216(5), 299-314. https://doi.org/10.1243/09544110260216577

If patient-specific finite element models of the spine could be developed, they would offer enormous opportunities in the diagnosis and management of back problems. Several generic models have been developed in the past, but there has been very littl... Read More about Patient-specific spine models. Part 1: Finite element analysis of the lumbar intervertebral disc—a material sensitivity study.

Algorithms for accurate rapid prototyping replication of cancellous bone voxel maps (2002)
Journal Article
Sisias, G., Phillips, R., Dobson, C., Fagan, M., & Langton, C. (2002). Algorithms for accurate rapid prototyping replication of cancellous bone voxel maps. Rapid Prototyping Journal, 8(1), 6-24. https://doi.org/10.1108/13552540210413266

A set of algorithms has been developed and evaluated for 3D and 21/2D rapid prototyping replication of 3D reconstructions of cancellous bone samples. The algorithms replicate a voxel map without any loss of fidelity, so as to increase the validity of... Read More about Algorithms for accurate rapid prototyping replication of cancellous bone voxel maps.

Smoothing of pixelated finite element models of cancellous bone structures and the effect on the predicted structural properties of the bone (2002)
Journal Article
Dobson, C. A., Sisias, G., Phillips, R., Langton, C. M., & Fagan, M. J. (2002). Smoothing of pixelated finite element models of cancellous bone structures and the effect on the predicted structural properties of the bone. Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine, 216(2), 145-149. https://doi.org/10.1243/0954411021536360

Many areas of biomedical engineering involve the modelling of biological systems, often using data from medical scanning techniques such as computed microtomography (μCT), and the prediction of the mechanical properties of these systems via finite el... Read More about Smoothing of pixelated finite element models of cancellous bone structures and the effect on the predicted structural properties of the bone.

Development of an artificial intervertebral disc for laboratory test spine (2001)
Journal Article
Fagan, M., Gillespie, P., Julian, S., Siddall, D., & Mohsen, A. (2001). Development of an artificial intervertebral disc for laboratory test spine. Journal of biomechanics, 34(Supplement 1), S59 - S60. https://doi.org/10.1016/S0021-9290%2801%2900129-4

A patient-specific finite element model of the spine is currently beingdeveloped to aid the surgeon in the diagnosis and clinical managementof spinal conditions1. To validate the application of the computermodel, a laboratory validation spine is bein... Read More about Development of an artificial intervertebral disc for laboratory test spine.

Stochastically simulated assessment of anabolic treatment following varying degrees of cancellous bone resorption (2000)
Journal Article
Langton, C., Haire, T., Ganney, P., Dobson, C., Fagan, M., Sisias, G., & Phillips, R. (2000). Stochastically simulated assessment of anabolic treatment following varying degrees of cancellous bone resorption. Bone, 27(1), 111-118. https://doi.org/10.1016/s8756-3282%2800%2900290-8

The aim of this study was to investigate the recovery in cancellous bone stiffness resulting from anabolic treatment following varying degrees of resorption, using a stochastic simulation applied to a simplistic structure consisting of five vertical... Read More about Stochastically simulated assessment of anabolic treatment following varying degrees of cancellous bone resorption.