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All Outputs (247)

A randomised clinical trial of ultrasound guided cannulation of difficult fistulae for dialysis access (2020)
Journal Article
Eves, J., Cai, P., Latham, R., Leung, C., Carradice, D., Chetter, I., & Smith, G. (in press). A randomised clinical trial of ultrasound guided cannulation of difficult fistulae for dialysis access. The journal of vascular access, https://doi.org/10.1177/1129729820954725

Background: Arteriovenous fistulae (AVF) are preferred for dialysis access but require accurate cannulation for effective dialysis. Evidence supports improvements in cannulation and complication rates using ultrasound guidance (USG) in cannulating ot... Read More about A randomised clinical trial of ultrasound guided cannulation of difficult fistulae for dialysis access.

Searching for Programme Theories for a realist evaluation: A case study comparing an academic database search and a simple Google search (2020)
Journal Article
Coleman, S., Wright, J. M., Nixon, J., Schoonhoven, L., Twiddy, M., & Greenhalgh, J. (2020). Searching for Programme Theories for a realist evaluation: A case study comparing an academic database search and a simple Google search. BMC Medical Research Methodology, 20(1), 217. https://doi.org/10.1186/s12874-020-01084-x

BACKGROUND: Realist methodologies are increasingly being used to evaluate complex interventions in health and social care. Programme theory (ideas and assumptions of how a particular intervention works) development is the first step in a realist eval... Read More about Searching for Programme Theories for a realist evaluation: A case study comparing an academic database search and a simple Google search.

Estimating global injuries morbidity and mortality: methods and data used in the Global Burden of Disease 2017 study (2020)
Journal Article
James, S. L., Bertolacci, G. J., Castle, C. D., Dingels, Z. V., Fox, J. T., Hamilton, E. B., …Vos, T. (2020). Estimating global injuries morbidity and mortality: methods and data used in the Global Burden of Disease 2017 study. Injury Prevention, 26, i125-i153. https://doi.org/10.1136/injuryprev-2019-043531

© Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY. Published by BMJ. BACKGROUND: While there is a long history of measuring death and disability from injuries, modern research methods must account for the wide spectrum of disabili... Read More about Estimating global injuries morbidity and mortality: methods and data used in the Global Burden of Disease 2017 study.

Mapping geographical inequalities in access to drinking water and sanitation facilities in low-income and middle-income countries, 2000-17 (2020)
Journal Article
Reiner, R. C., Local Burden of Disease WaSH Collaborators, & Soyiri, I. (2020). Mapping geographical inequalities in access to drinking water and sanitation facilities in low-income and middle-income countries, 2000-17. The Lancet global health, 8(9), e1162-e1185. https://doi.org/10.1016/S2214-109X%2820%2930278-3

Background Universal access to safe drinking water and sanitation facilities is an essential human right, recognised in the Sustainable Development Goals as crucial for preventing disease and improving human wellbeing. Comprehensive, high-resolutio... Read More about Mapping geographical inequalities in access to drinking water and sanitation facilities in low-income and middle-income countries, 2000-17.

The relationship between maternal personality disorder and early birth outcomes: A systematic review and meta-analysis (2020)
Journal Article
Marshall, C., Jomeen, J., Huang, C., & Martin, C. (2020). The relationship between maternal personality disorder and early birth outcomes: A systematic review and meta-analysis. International Journal of Environmental Research and Public Health, 17(16), 1-19. https://doi.org/10.3390/ijerph17165778

Title: Systematic review and meta-analysis of the relationship between maternal personality disorder and early birth outcomes. Background: Women with personality disorder are at risk of social and emotional problems which impact deleteriously on eve... Read More about The relationship between maternal personality disorder and early birth outcomes: A systematic review and meta-analysis.

Exploring feedback from research nurses in relation to the design and conduct of a randomised controlled trial of wound care treatments: a sequential, dependent, mixed-methods study (2020)
Journal Article
Long, J., Meethan, K., Arundel, C., Clarke, E., Firth, A., Sylvester, M., & Chetter, I. (2020). Exploring feedback from research nurses in relation to the design and conduct of a randomised controlled trial of wound care treatments: a sequential, dependent, mixed-methods study. Journal of tissue viability, 29(4), 342-347. https://doi.org/10.1016/j.jtv.2020.07.007

Background Research nurse involvement in trials is crucial to successful conduct, however their feedback on trial design and conduct is not necessarily always collected and shared. This study was designed to explore research nurse feedback in rela... Read More about Exploring feedback from research nurses in relation to the design and conduct of a randomised controlled trial of wound care treatments: a sequential, dependent, mixed-methods study.

Minimal clinically important differences in average, best, worst and current intensity and unpleasantness of chronic breathlessness (2020)
Journal Article
Ekström, M., Johnson, M. J., Huang, C., & Currow, D. C. (2020). Minimal clinically important differences in average, best, worst and current intensity and unpleasantness of chronic breathlessness. European respiratory journal, 56(2), Article 1902202. https://doi.org/10.1183/13993003.02202-2019

Copyright ©ERS 2020. BACKGROUND: Chronic breathlessness has devastating consequences. The minimal clinically important difference (MCID) for current intensity has been estimated as 9 mm on a 100-mm visual analogue scale (VAS). We aimed to determine M... Read More about Minimal clinically important differences in average, best, worst and current intensity and unpleasantness of chronic breathlessness.

Microplastic contamination of drinking water: a systematic review. (2020)
Journal Article
Danopoulos, E., Twiddy, M., & Rotchell, J. M. (2020). Microplastic contamination of drinking water: a systematic review. PLoS ONE, 15(7 July), Article e0236838. https://doi.org/10.1371/journal.pone.0236838

Background Microplastics (MPs) are omnipresent in the environment, including the human food chain; a likely important contributor to human exposure is drinking water. Objective To undertake a systematic review of MP contamination of drinking water... Read More about Microplastic contamination of drinking water: a systematic review..

Mapping geographical inequalities in oral rehydration therapy coverage in low-income and middle-income countries, 2000-17 Local Burden of Disease Diarrhoea Collaborators* (2020)
Journal Article
Local Burden of Disease Diarrhoea Collaborators, & Soyiri, I. (2020). Mapping geographical inequalities in oral rehydration therapy coverage in low-income and middle-income countries, 2000-17 Local Burden of Disease Diarrhoea Collaborators*. The Lancet global health, 8(8), e1038-e1060. https://doi.org/10.1016/S2214-109X%2820%2930230-8

Background Oral rehydration solution (ORS) is a form of oral rehydration therapy (ORT) for diarrhoea that has the potential to drastically reduce child mortality; yet, according to UNICEF estimates, less than half of children younger than 5 years w... Read More about Mapping geographical inequalities in oral rehydration therapy coverage in low-income and middle-income countries, 2000-17 Local Burden of Disease Diarrhoea Collaborators*.

Letter in Response to Grobler AC, Lee K. Intention-To-Treat Analyses for Randomized Controlled Trials in Hospice/Palliative Care Enhanced by Principled Methods to Handle Missing Data (2020)
Journal Article
Huang, C., Kochovska, S., & Currow, D. C. (2020). Letter in Response to Grobler AC, Lee K. Intention-To-Treat Analyses for Randomized Controlled Trials in Hospice/Palliative Care Enhanced by Principled Methods to Handle Missing Data. Journal of pain and symptom management, 60(4), e30-e31. https://doi.org/10.1016/j.jpainsymman.2020.07.004

high INtensity Interval Training In pATiEnts with intermittent claudication (INITIATE): protocol for a multi-centre, proof-of-concept, prospective interventional study (2020)
Journal Article
Pymer, S., Harwood, A., Ibeggazene, S., McGregor, G., Huang, C., Twiddy, M., …Chetter, I. C. (2020). high INtensity Interval Training In pATiEnts with intermittent claudication (INITIATE): protocol for a multi-centre, proof-of-concept, prospective interventional study. BMJ open, 10(7), Article e038825. https://doi.org/10.1136/bmjopen-2020-038825

Introduction: The first-line recommended treatment for patients with intermittent claudication (IC), is a supervised exercise programme (SEP), which includes a minimum of 2 hours exercise per week over a 12-week period. However, provision, uptake, an... Read More about high INtensity Interval Training In pATiEnts with intermittent claudication (INITIATE): protocol for a multi-centre, proof-of-concept, prospective interventional study.

A proposal for multidisciplinary tele-rehabilitation in the assessment and rehabilitation of COVID-19 survivors (2020)
Journal Article
Salawu, A., Green, A., Crooks, M. G., Brixey, N., Ross, D. H., & Sivan, M. (2020). A proposal for multidisciplinary tele-rehabilitation in the assessment and rehabilitation of COVID-19 survivors. International Journal of Environmental Research and Public Health, 17(13), 1-13. https://doi.org/10.3390/ijerph17134890

A global pandemic of a new highly contagious disease called COVID-19 resulting from coronavirus (severe acute respiratory syndrome (SARS)-Cov-2) infection was declared in February 2020. Though primarily transmitted through the respiratory system, oth... Read More about A proposal for multidisciplinary tele-rehabilitation in the assessment and rehabilitation of COVID-19 survivors.

Laparoscopic versus open colorectal surgery in the acute setting (LaCeS trial): a multicentre randomized feasibility trial (2020)
Journal Article
Cardozo, W., Baker, R., Berger, C., Chapman, S., Codd, R., Coyne, P., …Brown, J. (in press). Laparoscopic versus open colorectal surgery in the acute setting (LaCeS trial): a multicentre randomized feasibility trial. British journal of surgery, https://doi.org/10.1002/bjs.11703

Abstract Background Approximately 30,000 people per annum undergo major, emergency abdominal, gastrointestinal surgery, of which 36% (~10,800) are carried out for emergency colorectal pathology. Approximately 14% of all patients requiring emergency... Read More about Laparoscopic versus open colorectal surgery in the acute setting (LaCeS trial): a multicentre randomized feasibility trial.

The effects of the iPlayClean education programme on doping attitudes and susceptibility to use banned substances among high-level adolescent athletes from the UK: A cluster-randomised controlled trial (2020)
Journal Article
Nicholls, A. R., Morley, D., Thompson, M. A., Huang, C., Abt, G., Rothwell, M., …Ntoumanis, N. (2020). The effects of the iPlayClean education programme on doping attitudes and susceptibility to use banned substances among high-level adolescent athletes from the UK: A cluster-randomised controlled trial. International Journal of Drug Policy, 82, Article 102820. https://doi.org/10.1016/j.drugpo.2020.102820

Background: This study examined the effects of the iPlayClean anti-doping intervention on attitudes towards doping and susceptibility, and whether delivery mode affected the results. Methods: A total of 1,081 high-level UK athletes (14-18 years old... Read More about The effects of the iPlayClean education programme on doping attitudes and susceptibility to use banned substances among high-level adolescent athletes from the UK: A cluster-randomised controlled trial.

Mapping geographical inequalities in childhood diarrhoeal morbidity and mortality in low-income and middle-income countries, 2000-17: analysis for the Global Burden of Disease Study 2017 Local Burden of Disease Diarrhoea Collaborators* (2020)
Journal Article
Soyiri, I., & Local Burden of Disease Diarrhoea Collaborators. (2020). Mapping geographical inequalities in childhood diarrhoeal morbidity and mortality in low-income and middle-income countries, 2000-17: analysis for the Global Burden of Disease Study 2017 Local Burden of Disease Diarrhoea Collaborators*. Lancet, 395(10239), 1779-1801. https://doi.org/10.1016/S0140-6736%2820%2930114-8

Background Across low-income and middle-income countries (LMICs), one in ten deaths in children younger than 5 years is attributable to diarrhoea. The substantial between-country variation in both diarrhoea incidence and mortality is attributable t... Read More about Mapping geographical inequalities in childhood diarrhoeal morbidity and mortality in low-income and middle-income countries, 2000-17: analysis for the Global Burden of Disease Study 2017 Local Burden of Disease Diarrhoea Collaborators*.

The Effects of the iPlayClean Education Programme on Doping Attitudes and Susceptibility to use Banned Substances among High-Level Adolescent Athletes from the UK: A Cluster-Randomised Control Trial (2020)
Journal Article
Nicholls, A., Morley, D., Thompson, M. A., Huang, C., Abt, G., Rothwell, M., …Ntoumanis, N. (in press). The Effects of the iPlayClean Education Programme on Doping Attitudes and Susceptibility to use Banned Substances among High-Level Adolescent Athletes from the UK: A Cluster-Randomised Control Trial. International Journal of Drug Policy,

Background: This study examined the effects of the iPlayClean anti-doping intervention on attitudes towards doping and susceptibility, and whether delivery mode affected the results. Methods: A total of 1,081 high-level UK athletes (14-18 years old... Read More about The Effects of the iPlayClean Education Programme on Doping Attitudes and Susceptibility to use Banned Substances among High-Level Adolescent Athletes from the UK: A Cluster-Randomised Control Trial.

Prevalence and attributable health burden of chronic respiratory diseases, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017 (2020)
Journal Article
Soriano, J. B., Kendrick, P., Paulson, K., Gupta, V., Vos, T., GBD Chronic Respiratory Disease Collaborators, & Soyiri, I. (2020). Prevalence and attributable health burden of chronic respiratory diseases, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017. The lancet. Respiratory medicine, 8(6), 585-596. https://doi.org/10.1016/S2213-2600%2820%2930105-3

Background Previous attempts to characterise the burden of chronic respiratory diseases have focused only on specific disease conditions, such as chronic obstructive pulmonary disease (COPD) or asthma. In this study, we aimed to characterise the bur... Read More about Prevalence and attributable health burden of chronic respiratory diseases, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017.

A randomised Phase II trial of carboplatin and gemcitabine ± vandetanib in first-line treatment of patients with advanced urothelial cell cancer not suitable to receive cisplatin (2020)
Journal Article
Jones, R., Crabb, S., Chester, J., Elliott, T., Huddart, R., Birtle, A., …Griffiths, G. (2020). A randomised Phase II trial of carboplatin and gemcitabine ± vandetanib in first-line treatment of patients with advanced urothelial cell cancer not suitable to receive cisplatin. BJU international, 126(2), 292-299. https://doi.org/10.1111/bju.15096

Objectives To assess the efficacy and tolerability of the dual epidermal growth factor receptor/vascular endothelial growth factor receptor inhibitor, vandetanib, in combination with carboplatin and gemcitabine in the first‐line treatment of patient... Read More about A randomised Phase II trial of carboplatin and gemcitabine ± vandetanib in first-line treatment of patients with advanced urothelial cell cancer not suitable to receive cisplatin.

Considerations on equity in management of end-stage kidney disease in low- and middle-income countries (2020)
Journal Article
Van Biesen, W., Jha, V., Abu-Alfa, A. K., Andreoli, S. P., Ashuntantang, G., Bernieh, B., …Garcia Garcia, G. (2020). Considerations on equity in management of end-stage kidney disease in low- and middle-income countries. Kidney International Supplements, 10(1), e63-e71. https://doi.org/10.1016/j.kisu.2019.11.004

Achievement of equity in health requires development of a health system in which everyone has a fair opportunity to attain their full health potential. The current, large country-level variation in the reported incidence and prevalence of treated end... Read More about Considerations on equity in management of end-stage kidney disease in low- and middle-income countries.

Development and evaluation of a screening tool to aid the diagnosis of a cluster headache (2020)
Journal Article
Buture, A., Boland, J. W., Dikomitis, L., Huang, C., & Ahmed, F. (2020). Development and evaluation of a screening tool to aid the diagnosis of a cluster headache. Brain Sciences, 10(2), Article 77. https://doi.org/10.3390/brainsci10020077

Cluster headache (CH), a severe primary headache, is often misdiagnosed and mismanaged. The aim of this study was to develop and evaluate a screening tool to aid the diagnosis of CH. We developed a novel 12-item screening tool. This was comprised of... Read More about Development and evaluation of a screening tool to aid the diagnosis of a cluster headache.