All Outputs (25)

Dual-modal magnetic resonance/fluorescent zinc probes for pancreatic β-cell mass imaging (2015)
Journal Article
Stasiuk, G. J., Minuzzi, F., Sae-Heng, M., Rivas, C., Juretschke, H., Piemonti, L., …Long, N. J. (2015). Dual-modal magnetic resonance/fluorescent zinc probes for pancreatic β-cell mass imaging. Chemistry: a European journal, 21(13), 5023-5033. https://doi.org/10.1002/chem.201406008

Despite the contribution of changes in pancreatic β-cell mass to the development of all forms of diabetes mellitus, few robust approaches currently exist to monitor these changes prospectively in vivo. Although magnetic-resonance imaging (MRI) provid... Read More about Dual-modal magnetic resonance/fluorescent zinc probes for pancreatic β-cell mass imaging.

⁹⁹ᵐTc SPECT imaging agent based on cFLFLFK for the detection of FPR1 in inflammation (2015)
Journal Article
Stasiuk, G. J., Holloway, P. M., Rivas, C., Trigg, W., Luthra, S. K., Morrison Iveson, V., …Long, N. J. (2015). ⁹⁹ᵐTc SPECT imaging agent based on cFLFLFK for the detection of FPR1 in inflammation. Dalton Transactions : an international journal of inorganic chemistry, 44(11), 4986-4993. https://doi.org/10.1039/c4dt02980a

Non-invasive imaging of the inflammatory process can provide a great deal of insight into a wide variety of diseases states, aiding diagnosis, evaluation and effective targeted treatment. During inflammation, blood borne leukocytes are recruited, thr... Read More about ⁹⁹ᵐTc SPECT imaging agent based on cFLFLFK for the detection of FPR1 in inflammation.

Towards understanding the design of dual-modal MR/fluorescent probes to sense zinc ions (2014)
Journal Article
Rivas, C., Stasiuk, G. J., Sae-Heng, M., & Long, N. J. (2015). Towards understanding the design of dual-modal MR/fluorescent probes to sense zinc ions. Dalton Transactions : an international journal of inorganic chemistry, 44(11), 4976-4985. https://doi.org/10.1039/c4dt02981j

A series of gadolinium complexes were synthesised in order to test the design of dual-modal probes that display a change in fluorescence or relaxivity response upon binding of zinc. A dansyl-DO3ATA gadolinium complex [GdL1] displayed an increase and... Read More about Towards understanding the design of dual-modal MR/fluorescent probes to sense zinc ions.

Multimetallic complexes and functionalized gold nanoparticles based on a combination of d- and f-Elements (2014)
Journal Article
Stasiuk, G. J., Bell, J. D., Holmes, H., Sung, S., Toscani, A., Wainwright, L., …Wilton-Ely, J. D. E. T. (2014). Multimetallic complexes and functionalized gold nanoparticles based on a combination of d- and f-Elements. Inorganic chemistry, 53(4), 1989-2005. https://doi.org/10.1021/ic401936w

The new DO3A-derived dithiocarbamate ligand, DO3A-ᵗBu-CS₂K, is formed by treatment of the ammonium salt [DO3A-ᵗBu]HBr with K₂CO₃ and carbon disulfide. DO3A-ᵗBu-CS₂K reacts with the ruthenium complexes cis-[RuCl₂(dppm)₂] and [Ru(CH═CHC₆H₄Me-4)Cl(CO)(B... Read More about Multimetallic complexes and functionalized gold nanoparticles based on a combination of d- and f-Elements.

Lanthanide(III) complexes of rhodamine-DO3A conjugates as agents for dual-modal imaging (2013)
Journal Article
Rivas, C., Stasiuk, G. J., Gallo, J., Minuzzi, F., Rutter, G. A., & Long, N. J. (2013). Lanthanide(III) complexes of rhodamine-DO3A conjugates as agents for dual-modal imaging. Inorganic chemistry, 52(24), 14284-14293. https://doi.org/10.1021/ic402233g

Two novel dual-modal MRI/optical probes based on a rhodamine-DO3A conjugate have been prepared. The bis aqua-Gd(III) complex Gd.L1 and mono aqua-Gd(III) complex Gd.L2 behave as dual-modal imaging probes (r1 = 8.5 and 3.8 mM-1s-1 for Gd.L1 and Gd.L2 r... Read More about Lanthanide(III) complexes of rhodamine-DO3A conjugates as agents for dual-modal imaging.