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Effects of exercise training on cardiovascular risk within HIV-infected adults in Malawi, Africa (2025)
Thesis
Namanja, A. (2025). Effects of exercise training on cardiovascular risk within HIV-infected adults in Malawi, Africa [Doctorate thesis, University of Hull]. https://hull-repository.worktribe.com/output/5461880

Background: Antiretroviral therapy (ART) has successfully improved survival rate among people living with human immunodeficiency virus (HIV) infection (PLHIV), especially in Sub-Saharan Africa (SSA). Seventy percent (70%) of the global population of... Read More about Effects of exercise training on cardiovascular risk within HIV-infected adults in Malawi, Africa.

Exercise, Postprandial Lipids and Risk of Non-Alcoholic Fatty Liver Disease (2024)
Thesis
Page, R. (2024). Exercise, Postprandial Lipids and Risk of Non-Alcoholic Fatty Liver Disease [Doctorate thesis, University of Hull]. https://hull-repository.worktribe.com/output/4866495

Non-alcoholic fatty liver disease (NAFLD) represents a spectrum of liver disorders from fatty accumulation to non-alcoholic steatohepatitis (NASH). The worldwide prevalence of NAFLD is estimated to be 30% and it is frequently observed in those living... Read More about Exercise, Postprandial Lipids and Risk of Non-Alcoholic Fatty Liver Disease.

Delivering effective, comprehensive, multi-exercise component cardiac rehabilitation (CR) for chronic heart failure patients in low resource settings in sub-Saharan Africa: Queen Elizabeth Central Hospital—(QECH-CR) randomised CR study, Malawi (2024)
Journal Article
Namanja, A., Nyondo, D., Banda, T., Mndinda, E., Midgely, A., Hobkirk, J., Carroll, S., & Kumwenda, J. (2024). Delivering effective, comprehensive, multi-exercise component cardiac rehabilitation (CR) for chronic heart failure patients in low resource settings in sub-Saharan Africa: Queen Elizabeth Central Hospital—(QECH-CR) randomised CR study, Malawi. PLoS ONE, 19(5 May), e0297564. https://doi.org/10.1371/journal.pone.0297564

Background The delivery of Cardiac Rehabilitation (CR) and attaining evidence-based treatment goals are challenging in developing countries, such as Malawi. The aims of this study were to (i) assess the effects of exercise training/ CR programme on c... Read More about Delivering effective, comprehensive, multi-exercise component cardiac rehabilitation (CR) for chronic heart failure patients in low resource settings in sub-Saharan Africa: Queen Elizabeth Central Hospital—(QECH-CR) randomised CR study, Malawi.

Confirming the attainment of maximal oxygen uptake within special and clinical groups: A systematic review and meta-analysis of cardiopulmonary exercise test and verification phase protocols (2024)
Journal Article
Costa, V. A. B., Midgley, A. W., Baumgart, J. K., Carroll, S., Astorino, T. A., Schaun, G. Z., Fonseca, G. F., & Cunha, F. A. (2024). Confirming the attainment of maximal oxygen uptake within special and clinical groups: A systematic review and meta-analysis of cardiopulmonary exercise test and verification phase protocols. PLoS ONE, 19(3 March), e0299563. https://doi.org/10.1371/journal.pone.0299563

Background and aim A plateau in oxygen uptake (VO_2) during an incremental cardiopulmonary exercise test (CPET) to volitional exhaustion appears less likely to occur in special and clinical populations. Secondary maximal oxygen uptake (VO_2max) crite... Read More about Confirming the attainment of maximal oxygen uptake within special and clinical groups: A systematic review and meta-analysis of cardiopulmonary exercise test and verification phase protocols.

Parental history of cardiovascular risk factors and childhood cardiometabolic risk: The preventive effects of cardiorespiratory fitness and waist circumference within offspring (2024)
Journal Article
Brand, C., Fernandes Dias, A., Fochesatto, C. F., Gaya, A. R., Carroll, S., Hobkirk, J. P., Pollo Renner, J. D., & Reuter, C. P. (2024). Parental history of cardiovascular risk factors and childhood cardiometabolic risk: The preventive effects of cardiorespiratory fitness and waist circumference within offspring. Baltic Journal of Health and Physical Activity, 16(2), 8. https://doi.org/10.29359/BJHPA.16.2.08

Introduction: In addition to childhood obesity status, the family history of cardiovascular disorders might be used as a tool for screening youth to identify those at the highest risk of devel-oping metabolic impairments later in life. Thus, the aim... Read More about Parental history of cardiovascular risk factors and childhood cardiometabolic risk: The preventive effects of cardiorespiratory fitness and waist circumference within offspring.

High-intensity interval training in patients with intermittent claudication (2023)
Presentation / Conference Contribution
Pymer, S., Harwood, A. E., Prosser, J., Waddell, A., Rhavindhran, B., McGregor, G., Ibeggazene, S., Huang, C., Twiddy, M., Nicholls, A. R., Ingle, L., Carroll, S., He, H., Long, J., Rooms, M., & Chetter, I. C. (2023). High-intensity interval training in patients with intermittent claudication. Journal of vascular surgery, 78(4), 1048-1056.e4. https://doi.org/10.1016/j.jvs.2023.05.045

Objective: Provision, uptake, adherence, and completion rates for supervised exercise programs (SEP) for intermittent claudication (IC) are low. A shorter, more time-efficient, 6-week, high-intensity interval training (HIIT) program may be an effecti... Read More about High-intensity interval training in patients with intermittent claudication.

Serum transthyretin and aminotransferases are associated with lean mass in people with coronary heart disease: Further insights from the CARE-CR study (2023)
Journal Article
James, E., Goodall, S., Nichols, S., Walker, K., Carroll, S., O’Doherty, A. F., & Ingle, L. (2023). Serum transthyretin and aminotransferases are associated with lean mass in people with coronary heart disease: Further insights from the CARE-CR study. Frontiers in Medicine, 10, 1094733. https://doi.org/10.3389/fmed.2023.1094733

Background: Low muscle mass disproportionately affects people with coronary heart disease compared to healthy controls but is under-researched and insufficiently treated. Inflammation, poor nutrition, and neural decline might contribute to low muscle... Read More about Serum transthyretin and aminotransferases are associated with lean mass in people with coronary heart disease: Further insights from the CARE-CR study.

Metabolic risk is associated with sociodemographic characteristics in adolescents from both rural and urban regions from southern Brazil (2022)
Journal Article
de Souza, S., Francisco de Castro Silveira, J., Marques, K. C., Gaya, A. R., Franke, S. I. R., Renner, J. D. P., Hobkirk, J. P., Carroll, S., & Reuter, C. P. (2022). Metabolic risk is associated with sociodemographic characteristics in adolescents from both rural and urban regions from southern Brazil. BMC Pediatrics, 22(1), 324. https://doi.org/10.1186/s12887-022-03386-z

Background: The prevalence of several cardiovascular metabolic disorders are increasingly cause for concern in adolescents worldwide. Given the complex interrelations between metabolic risk (MR) and sociodemographic variables, the present study aims... Read More about Metabolic risk is associated with sociodemographic characteristics in adolescents from both rural and urban regions from southern Brazil.

Ratings of perceived exertion at the ventilatory anaerobic threshold in people with coronary heart disease: A CARE CR study (2021)
Journal Article
Nichols, S., Engin, B., Carroll, S., Buckley, J., & Ingle, L. (2021). Ratings of perceived exertion at the ventilatory anaerobic threshold in people with coronary heart disease: A CARE CR study. Annals of physical and rehabilitation medicine, 64(6), 101462. https://doi.org/10.1016/j.rehab.2020.101462

Background: Exercise prescription guidelines for individuals undergoing cardiovascular rehabilitation (CR) are often based on heart rate training zones and rating of perceived exertion (RPE). United Kingdom guidelines indicate that patients should ex... Read More about Ratings of perceived exertion at the ventilatory anaerobic threshold in people with coronary heart disease: A CARE CR study.

Love is in the hair: arginine methylation of human hair proteins as novel cardiovascular biomarkers (2021)
Journal Article
Marsden, A. J., Riley, D. R., Birkett, S., Rodriguez-Barucg, Q., Guinn, B. a., Carroll, S., Ingle, L., Sathyapalan, T., & Beltran-Alvarez, P. (2021). Love is in the hair: arginine methylation of human hair proteins as novel cardiovascular biomarkers. Amino acids. https://doi.org/10.1007/s00726-021-03024-5

Cardiovascular disease is the major cause of death worldwide. Extensive cardiovascular biomarkers are available using blood tests but very few, if any, investigations have described non-invasive tests for cardiovascular biomarkers based on readily av... Read More about Love is in the hair: arginine methylation of human hair proteins as novel cardiovascular biomarkers.

Is a verification phase useful for confirming maximal oxygen uptake in apparently healthy adults? A systematic review and meta-analysis (2021)
Journal Article
Costa, V. A. B., Midgley, A. W., Carroll, S., Astorino, T. A., de Paula, T., Farinatti, P., & Cunha, F. A. (2021). Is a verification phase useful for confirming maximal oxygen uptake in apparently healthy adults? A systematic review and meta-analysis. PLoS ONE, 16(2 February), e0247057. https://doi.org/10.1371/journal.pone.0247057

© 2021 Costa et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are cred... Read More about Is a verification phase useful for confirming maximal oxygen uptake in apparently healthy adults? A systematic review and meta-analysis.

The effects of exercise to promote quality of life in individuals with traumatic brain injuries: a systematic review (2020)
Journal Article
O'Caroll, G., King, S. L., Carroll, S., Perry, J., & Vanicek, N. (2020). The effects of exercise to promote quality of life in individuals with traumatic brain injuries: a systematic review. Brain Injury, 1-13. https://doi.org/10.1080/02699052.2020.1812117

© 2020 Taylor & Francis Group, LLC. Objective: To systematically review the effects of exercise interventions that may enhance quality of life (QOL) in individuals with traumatic brain injury (TBI). Methods: A systematic search was conducted using... Read More about The effects of exercise to promote quality of life in individuals with traumatic brain injuries: a systematic review.

Considering the feasibility, tolerability and safety of high intensity interval training as a novel treatment for patients with intermittent claudication (2020)
Journal Article
Pymer, S., Ibeggazene, S., Palmer, J., Smith, G. E., Carroll, S., Ingle, L., Harwood, A., & Chetter, I. C. (2021). Considering the feasibility, tolerability and safety of high intensity interval training as a novel treatment for patients with intermittent claudication [HIIT for Intermittent Claudication]. Journal of Cardiopulmonary Rehabilitation and Prevention, 41(3), 188-193. https://doi.org/10.1097/HCR.0000000000000551

Considering the Feasibility, Tolerability and Safety of High-Intensity Interval Training as a Novel Treatment for Patients with Intermittent Claudication.

Structured Abstract
Purpose: This study assessed the feasibility, tolerability, safety and... Read More about Considering the feasibility, tolerability and safety of high intensity interval training as a novel treatment for patients with intermittent claudication.

Characterising the application of the “progressive overload” principle of exercise training within cardiac rehabilitation: a United Kingdom-based community programme (2020)
Journal Article
Khushhal, A., Nichols, S., Carroll, S., Abt, G., & Ingle, L. (2020). Characterising the application of the “progressive overload” principle of exercise training within cardiac rehabilitation: a United Kingdom-based community programme. PLoS ONE, 15(8), e0237197. https://doi.org/10.1371/journal.pone.0237197

BACKGROUND: Recent concerns have cast doubt over the effectiveness of cardiac rehabilitation [CR] programmes for improving cardiorespiratory fitness [CRF] in patients with a history of cardiac disease in the United Kingdom [UK]. We aimed to character... Read More about Characterising the application of the “progressive overload” principle of exercise training within cardiac rehabilitation: a United Kingdom-based community programme.

high INtensity Interval Training In pATiEnts with intermittent claudication (INITIATE): protocol for a multi-centre, proof-of-concept, prospective interventional study (2020)
Journal Article
Pymer, S., Harwood, A., Ibeggazene, S., McGregor, G., Huang, C., Twiddy, M., Nicholls, A. R., Ingle, L., Carroll, S., Long, J., Rooms, M., & Chetter, I. C. (2020). high INtensity Interval Training In pATiEnts with intermittent claudication (INITIATE): protocol for a multi-centre, proof-of-concept, prospective interventional study. BMJ open, 10(7), e038825. https://doi.org/10.1136/bmjopen-2020-038825

Introduction: The first-line recommended treatment for patients with intermittent claudication (IC), is a supervised exercise programme (SEP), which includes a minimum of 2 hours exercise per week over a 12-week period. However, provision, uptake, an... Read More about high INtensity Interval Training In pATiEnts with intermittent claudication (INITIATE): protocol for a multi-centre, proof-of-concept, prospective interventional study.

Routine exercise-based cardiac rehabilitation does not increase aerobic fitness: A CARE CR study (2020)
Journal Article
Nichols, S., Taylor, C., Goodman, T., Page, R., Kallvikbacka-Bennett, A., Nation, F., Clark, A. L., Birkett, S. T., Carroll, S., & Ingle, L. (2020). Routine exercise-based cardiac rehabilitation does not increase aerobic fitness: A CARE CR study. International journal of cardiology, 305, 25-34. https://doi.org/10.1016/j.ijcard.2020.01.044

© 2020 The Authors Background: Recent evidence suggests that routine exercise-based cardiac rehabilitation (CR) may not lead to a substantial increase in estimated peak oxygen uptake (V̇O2peak). This could reduce the potential benefits of CR and expl... Read More about Routine exercise-based cardiac rehabilitation does not increase aerobic fitness: A CARE CR study.

The effect of atorvastatin (and subsequent metformin) on adipose tissue acylation-stimulatory-protein concentration and inflammatory biomarkers in overweight/obese women with polycystic ovary syndrome (2019)
Journal Article
Sathyapalan, T., Hobkirk, J. P., Javed, Z., Carroll, S., Coady, A. M., Pemberton, P., Smith, A., Cianflone, K., & Atkin, S. L. (2019). The effect of atorvastatin (and subsequent metformin) on adipose tissue acylation-stimulatory-protein concentration and inflammatory biomarkers in overweight/obese women with polycystic ovary syndrome. Frontiers in endocrinology, 10(JUN), 394. https://doi.org/10.3389/fendo.2019.00394

Copyright © 2019 Sathyapalan, Hobkirk, Javed, Carroll, Coady, Pemberton, Smith, Cianflone and Atkin. Background: Atorvastatin has been shown to improve cardiovascular risk (CVR) indices in women with polycystic ovary syndrome (PCOS). Low-grade chroni... Read More about The effect of atorvastatin (and subsequent metformin) on adipose tissue acylation-stimulatory-protein concentration and inflammatory biomarkers in overweight/obese women with polycystic ovary syndrome.

Insufficient exercise intensity for clinical benefit? Monitoring and quantification of a community-based Phase III cardiac rehabilitation programme: A United Kingdom perspective (2019)
Journal Article
Khushhal, A., Nichols, S., Carroll, S., Abt, G., & Ingle, L. (2019). Insufficient exercise intensity for clinical benefit? Monitoring and quantification of a community-based Phase III cardiac rehabilitation programme: A United Kingdom perspective. PLoS ONE, 14(6), e0217654. https://doi.org/10.1371/journal.pone.0217654

Abstract:
Background: In recent years, criticism of the percentage range approach for individualised exercise prescription has intensified and we were concerned that sub-optimal exercise dose (especially intensity) may be in part responsible for the... Read More about Insufficient exercise intensity for clinical benefit? Monitoring and quantification of a community-based Phase III cardiac rehabilitation programme: A United Kingdom perspective.

Influence of appendicular skeletal muscle mass on resting metabolic equivalents in patients with cardiovascular disease: Implications for exercise training and prescription (2019)
Journal Article
Nichols, S., O'Doherty, A., Carroll, S., & Ingle, L. (2019). Influence of appendicular skeletal muscle mass on resting metabolic equivalents in patients with cardiovascular disease: Implications for exercise training and prescription. European Journal of Preventive Cardiology. https://doi.org/10.1177/2047487319856432

Cardiorespiratory fitness as a predictor of short‐term and lifetime estimated cardiovascular disease risk (2019)
Journal Article
Swainson, M. G., Ingle, L., & Carroll, S. (2019). Cardiorespiratory fitness as a predictor of short‐term and lifetime estimated cardiovascular disease risk [Normative fitness thresholds and CVD risk]. Scandinavian Journal of Medicine and Science in Sports, 29(9), 1402-1413. https://doi.org/10.1111/sms.13468

Development of cardiovascular disease (CVD) remains a public health concern for young-to-middle-aged adults, now exacerbated by the increasing prevalence of obesity and sedentary lifestyles. Cardiorespiratory fitness (CRF) improves the reclassificati... Read More about Cardiorespiratory fitness as a predictor of short‐term and lifetime estimated cardiovascular disease risk.