The adaptation, face, and content validation of a needs assessment tool: progressive disease for people with interstitial lung disease (2016)
Journal Article
Boland, J. W., Reigada, C., Yorke, J., Hart, S. P., Bajwah, S., Ross, J., …Johnson, M. J. (2016). The adaptation, face, and content validation of a needs assessment tool: progressive disease for people with interstitial lung disease. Journal of palliative medicine, 19(5), 549-555. https://doi.org/10.1089/jpm.2015.0355

Background: Irrreversible interstitial lung disease (ILD) is associated with high morbidity and mortality. Palliative care needs of patients and caregivers are not routinely assessed; there is no tool to identify needs and triage support in clinical... Read More about The adaptation, face, and content validation of a needs assessment tool: progressive disease for people with interstitial lung disease.

Coagulation and anticoagulation in idiopathic pulmonary fibrosis (2015)
Journal Article
Crooks, M. G., & Hart, S. P. (2015). Coagulation and anticoagulation in idiopathic pulmonary fibrosis. European Respiratory Review, 24(137), 392-399. https://doi.org/10.1183/16000617.00008414

Idiopathic pulmonary fibrosis (IPF) is an incurable, progressive interstitial lung disease with a prognosis that is worse than that of many cancers. Epidemiological studies have demonstrated a link between IPF and thrombotic vascular events. Coagulat... Read More about Coagulation and anticoagulation in idiopathic pulmonary fibrosis.

Magnetoencephalography to investigate central perception of exercise-induced breathlessness in people with chronic lung disease: A feasibility pilot (2015)
Journal Article
Johnson, M. J., Simpson, M. I., Currow, D. C., Millman, R. E., Hart, S. P., & Green, G. (2015). Magnetoencephalography to investigate central perception of exercise-induced breathlessness in people with chronic lung disease: A feasibility pilot. BMJ open, 5(6), Article ARTN e007535. https://doi.org/10.1136/bmjopen-2014-007535

Objectives: Neuroimaging in chronic breathlessness is challenging. The study objective was to test the feasibility of magnetoencephalography (MEG) for functional neuroimaging of people with chronic breathlessness. Design: Feasibility pilot study. Set... Read More about Magnetoencephalography to investigate central perception of exercise-induced breathlessness in people with chronic lung disease: A feasibility pilot.

Autonomic dysregulation: A mechanism of asthma death (2014)
Journal Article
Morjaria, J. B., Rowland, T., Tailor, P., Hyder, S., Wright, C. E., Hart, S. P., & Morice, A. H. (2014). Autonomic dysregulation: A mechanism of asthma death. European respiratory journal, 44(5), 1357-1360. https://doi.org/10.1183/09031936.00076414

Increased platelet reactivity in idiopathic pulmonary fibrosis is mediated by a plasma factor (2014)
Journal Article
Crooks, M. G., Fahim, A., Naseem, K. M., Morice, A. H., & Hart, S. P. (2014). Increased platelet reactivity in idiopathic pulmonary fibrosis is mediated by a plasma factor. PLoS ONE, 9(10), Article ARTN e111347. https://doi.org/10.1371/journal.pone.0111347

Introduction Idiopathic Pulmonary Fibrosis (IPF) is a progressive, incurable fibrotic interstitial lung disease with a prognosis worse than many cancers. Its pathogenesis is poorly understood. Activated platelets can release pro-fibrotic mediators th... Read More about Increased platelet reactivity in idiopathic pulmonary fibrosis is mediated by a plasma factor.

Increased platelet binding to circulating monocytes in idiopathic pulmonary fibrosis. (2014)
Journal Article
Fahim, A., Crooks, M. G., Morice, A. H., & Hart, S. P. (2014). Increased platelet binding to circulating monocytes in idiopathic pulmonary fibrosis. Lung, 192(2), 277-284. https://doi.org/10.1007/s00408-013-9546-5

Purpose Idiopathic pulmonary fibrosis (IPF) is the most common idiopathic interstitial pneumonia and its prognosis is poor. Epidemiological evidence suggests an association of IPF with vascular disease and thrombotic tendency, which may be related to... Read More about Increased platelet binding to circulating monocytes in idiopathic pulmonary fibrosis..

Serum carcinoembryonic antigen correlates with severity of idiopathic pulmonary fibrosis (2012)
Journal Article
Fahim, A., Crooks, M., Wilmot, R., Campbell, A. P., Morice, A., & Hart, S. (2012). Serum carcinoembryonic antigen correlates with severity of idiopathic pulmonary fibrosis. Respirology : official journal of the Asian Pacific Society of Respirology, 17(8), 1247-1252. https://doi.org/10.1111/j.1440-1843.2012.02231.x

Background and objective: Idiopathic pulmonary fibrosis (IPF) is the commonest idiopathic interstitial pneumonia and carries a poor prognosis. Epidemiological evidence suggests that patients with IPF have an increased risk of developing lung cancer.... Read More about Serum carcinoembryonic antigen correlates with severity of idiopathic pulmonary fibrosis.

Idiopathic Pulmonary Fibrosis is Associated with Circulating Antiepithelial Antibodies (2012)
Journal Article
Fahim, A., Chong, M. C., Crooks, M. G., & Hart, S. P. (2012). Idiopathic Pulmonary Fibrosis is Associated with Circulating Antiepithelial Antibodies. Lung, 190(4), 451-458. https://doi.org/10.1007/s00408-012-9390-z

PurposeIdiopathic pulmonary fibrosis (IPF) is a restrictive fibrotic lung disease of uncertain etiology. Alveolar epithelial injury may be one of the inciting triggers in the pathogenesis of this disorder. We hypothesized that circulating antibodies... Read More about Idiopathic Pulmonary Fibrosis is Associated with Circulating Antiepithelial Antibodies.

Characterization of the effects of cross-linking of macrophage CD44 associated with increased phagocytosis of apoptotic PMN (2012)
Journal Article
Hart, S. P., Rossi, A. G., Haslett, C., & Dransfield, I. (2012). Characterization of the effects of cross-linking of macrophage CD44 associated with increased phagocytosis of apoptotic PMN. PLoS ONE, 7(3), e33142. https://doi.org/10.1371/journal.pone.0033142

Control of macrophage capacity for apoptotic cell clearance by soluble mediators such as cytokines, prostaglandins and lipoxins, serum proteins, and glucocorticoids may critically determine the rate at which inflammation resolves. Previous studies su... Read More about Characterization of the effects of cross-linking of macrophage CD44 associated with increased phagocytosis of apoptotic PMN.

Copy number variation of FCGR3B is associated with susceptibility to idiopathic pulmonary fibrosis (2010)
Journal Article
Bournazos, S., Bournazou, I., Murchison, J. T., Wallace, W. A., McFarlane, P., Hirani, N., …Hart, S. P. (2011). Copy number variation of FCGR3B is associated with susceptibility to idiopathic pulmonary fibrosis. Respiration, 81(2), 142-149. https://doi.org/10.1159/000321997

Background: Several genes exhibit copy number variation (CNV), including FCGR3B which encodes the IgG receptor FcγRIIIb. Engagement of Fcγ receptors by IgG complexes may contribute to the pathogenesis of idiopathic pulmonary fibrosis (IPF). Objective... Read More about Copy number variation of FCGR3B is associated with susceptibility to idiopathic pulmonary fibrosis.