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Projects (23)

SURPASS EARLY: A Randomised, Open-Label, Parallel-Group, Two-Arm, Phase 4 Study to Evaluate the Long-Term Efficacy and Safety of Tirzepatide Compared with Intensified Conventional Care in Adults When Initiating Treatment Early in the Course of Type 2 Diabetes Sep 1, 2022 - Aug 31, 2027
A Randomised, Open-Label, Parallel-Group, Two-Arm, Phase 4 Study to Evaluate the Long-Term Efficacy and Safety of Tirzepatide Compared with Intensified Conventional Care in Adults When Initiating Treatment Early in the Course of Type 2 Diabetes (SURP... Read More about SURPASS EARLY: A Randomised, Open-Label, Parallel-Group, Two-Arm, Phase 4 Study to Evaluate the Long-Term Efficacy and Safety of Tirzepatide Compared with Intensified Conventional Care in Adults When Initiating Treatment Early in the Course of Type 2 Diabetes.

CRN funding - HYPER AID Aug 1, 2022 - Mar 31, 2023
0.5 funding for Dana Schofield for 8 months from 01/08/2022 - 31/03/2023
Support a concerted effort to maximise recruitment to this Diabetes study in Yorkshire and Humber. Although recruitment target has been met, global recruitment (national... Read More about CRN funding - HYPER AID.

Development and pilot of the “Living with Polycystic Ovary Syndrome (PCOS)” structured education programme Apr 1, 2019 - Sep 30, 2021
Polycystic ovary syndrome (PCOS) is the most common endocrine condition in reproductive age group females and it is associated with various clinical features including irregular periods, male-pattern hair loss from the head and excess hair in other b... Read More about Development and pilot of the “Living with Polycystic Ovary Syndrome (PCOS)” structured education programme.

TSB Costs (Study 1, 2, 3 & 4): In vitro and in vivo assessment of polyphenol extracts on cardiovascular indices Jan 1, 2012 - Aug 1, 2016
Evidence suggests dietary plant polyphenols are associated with reducing indices of cardiovascular disease such as endothelial dysfunction, insulin resistance and hypertension. The key objectives of this translational research proposal are to study a... Read More about TSB Costs (Study 1, 2, 3 & 4): In vitro and in vivo assessment of polyphenol extracts on cardiovascular indices.

PIONEER5: Efficacy and safety of oral semaglutide versus placebo in subjects with type 2 diabetes and moderate renal impairment Nov 1, 2016 - Oct 31, 2019
Primary objective:
To compare the effect of once-daily dosing of 14 mg oral semaglutide versus placebo, both in combination with metformin and/or sulfonylurea, basal insulin alone or metformin in combination with basal insulin on glycaemic con... Read More about PIONEER5: Efficacy and safety of oral semaglutide versus placebo in subjects with type 2 diabetes and moderate renal impairment.