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Bioassay complexities – exploring challenges in aquatic chemosensory research (2024)
Journal Article
Hardege, J., Fletcher, N., Burnett, J., Ohnstad, H., & Bartels-Hardege, H. (2024). Bioassay complexities – exploring challenges in aquatic chemosensory research. Frontiers in ecology and evolution, 11, Article 1293585. https://doi.org/10.3389/fevo.2023.1293585

Chemosensory science, the study of how organisms produce and assess olfactory information is central to our understanding of how organisms interact and gain information about their environment. Signalling cue identification in aquatic systems lags ou... Read More about Bioassay complexities – exploring challenges in aquatic chemosensory research.

The physiological and behavioural responses of the shore crab Carcinus meanas (L) to near-future levels of ocean acidification. (2023)
Thesis
Monaghan, A. (2023). The physiological and behavioural responses of the shore crab Carcinus meanas (L) to near-future levels of ocean acidification. (Thesis). University of Hull. Retrieved from https://hull-repository.worktribe.com/output/4564060

Ocean acidification as a result of increased anthropogenic Carbon Dioxide is a widely documented threat to marine life as a whole. According to current predictions, ocean pH is set to continue its hereto unprecedented level of decrease throughout the... Read More about The physiological and behavioural responses of the shore crab Carcinus meanas (L) to near-future levels of ocean acidification..

Hermit crabs as model species for investigating the behavioural responses to pollution (2023)
Journal Article
Briffa, M., Arnott, G., & Hardege, J. D. (2024). Hermit crabs as model species for investigating the behavioural responses to pollution. The Science of the total environment, 906, Article 167360. https://doi.org/10.1016/j.scitotenv.2023.167360

Human impacts on the environment affect organisms at all levels of biological organisation and ultimately can change their phenotype. Over time, phenotypic change may arise due to selection but individual phenotypes are also subject to change via gen... Read More about Hermit crabs as model species for investigating the behavioural responses to pollution.

Heat induces multiomic and phenotypic stress propagation in zebrafish embryos (2023)
Journal Article
Feugere, L., Bates, A., Emagbetere, T., Chapman, E., Malcolm, L., Bulmer, K., …Wollenberg Valero, K. C. (2023). Heat induces multiomic and phenotypic stress propagation in zebrafish embryos. PNAS Nexus, 2(5), Article pgad137. https://doi.org/10.1093/pnasnexus/pgad137

Heat alters biology from molecular to ecological levels, but may also have unknown indirect effects. This includes the concept that animals exposed to abiotic stress can induce stress in naive receivers. Here, we provide a comprehensive picture of th... Read More about Heat induces multiomic and phenotypic stress propagation in zebrafish embryos.

The Readiness of Water Molecules to Split into Hydrogen + Oxygen: A Proposed New Aspect of Water Splitting (2023)
Journal Article
Schäfer, H., Schuster, A., Kunis, S., Bookholt, T., Hardege, J., Ruewe, K., & Brune, J. (in press). The Readiness of Water Molecules to Split into Hydrogen + Oxygen: A Proposed New Aspect of Water Splitting. Advanced materials, Article 2300099. https://doi.org/10.1002/adma.202300099

The potential of the anode, at which the evolution of oxygen begins, is a key parameter that describes how well water is split in water electrolyzers. Research efforts related to electrocatalytically initiated water splitting that aim at reducing the... Read More about The Readiness of Water Molecules to Split into Hydrogen + Oxygen: A Proposed New Aspect of Water Splitting.

Becoming nose-blind—Climate change impacts on chemical communication (2022)
Journal Article
Roggatz, C. C., Saha, M., Blanchard, S., Schirrmacher, P., Fink, P., Verheggen, F., & Hardege, J. D. (2022). Becoming nose-blind—Climate change impacts on chemical communication. Global change biology, https://doi.org/10.1111/gcb.16209

Chemical communication via infochemicals plays a pivotal role in ecological interactions, allowing organisms to sense their environment, locate predators, food, habitats, or mates. A growing number of studies suggest that climate change-associated st... Read More about Becoming nose-blind—Climate change impacts on chemical communication.

Modelling Antifouling compounds of Macroalgal Holobionts in Current and Future pH Conditions (2022)
Journal Article
Hardege, J. D., Roggatz, C. C., & Saha, M. (2022). Modelling Antifouling compounds of Macroalgal Holobionts in Current and Future pH Conditions. Journal of Chemical Ecology, https://doi.org/10.1007/s10886-021-01340-4

Marine macroalgae are important ecosystem engineers in marine coastal habitats. Macroalgae can be negatively impacted through excessive colonization by harmful bacteria, fungi, microalgae, and macro-colonisers and thus employ a range of chemical comp... Read More about Modelling Antifouling compounds of Macroalgal Holobionts in Current and Future pH Conditions.

A pheromone bouquet controls the reproductive behaviour of the male shore crab, Carcinus maenas (2021)
Journal Article
Fletcher, N., Terschak, J. A., Bartels-Hardege, H. D., Bublitz, R., Schirrmacher, P., & Hardege, J. D. (2022). A pheromone bouquet controls the reproductive behaviour of the male shore crab, Carcinus maenas. Aquatic ecology, 56, 419–427. https://doi.org/10.1007/s10452-021-09930-w

The reproduction of many brachyuran crustaceans involves the formation of mating pairs often around the time of the female moult with attraction of a sexual partner and mating behaviour controlled by sex pheromones. In shore crabs, Carcinus maenas, f... Read More about A pheromone bouquet controls the reproductive behaviour of the male shore crab, Carcinus maenas.

Behavioural stress propagation in benthic invertebrates caused by acute pH drop-induced metabolites (2021)
Journal Article
Feugere, L., Angell, L., Fagents, J., Nightingale, R., Rowland, K., Skinner, S., …Wollenberg Valero, K. C. (2021). Behavioural stress propagation in benthic invertebrates caused by acute pH drop-induced metabolites. Frontiers in Marine Science, 8, Article 773870. https://doi.org/10.3389/fmars.2021.773870

Studies on pH stress in marine animals typically focus on direct or species-specific aspects. We here test the hypothesis that a drop to pH = 7.6 indirectly affects the intra- and interspecific interactions of benthic invertebrates by means of chemic... Read More about Behavioural stress propagation in benthic invertebrates caused by acute pH drop-induced metabolites.

The Nereid on the rise: Platynereis as a model system (2021)
Journal Article
Özpolat, B. D., Randel, N., Williams, E. A., Bezares-Calderón, L. A., Andreatta, G., Balavoine, G., …Arendt, D. (2021). The Nereid on the rise: Platynereis as a model system. EvoDevo, 12(1), Article 10. https://doi.org/10.1186/s13227-021-00180-3

The Nereid Platynereis dumerilii (Audouin and Milne Edwards (Annales des Sciences Naturelles 1:195–269, 1833) is a marine annelid that belongs to the Nereididae, a family of errant polychaete worms. The Nereid shows a pelago-benthic life cycle: as a... Read More about The Nereid on the rise: Platynereis as a model system.

Acidification can directly affect olfaction in marine organisms (2021)
Journal Article
Porteus, C. S., Roggatz, C. C., Velez, Z., Hardege, J. D., & Hubbard, P. C. (2021). Acidification can directly affect olfaction in marine organisms. The journal of experimental biology, 224(14), https://doi.org/10.1242/jeb.237941

In the past decade, many studies have investigated the effects of low pH/high CO2 as a proxy for ocean acidification on olfactory-mediated behaviours of marine organisms. The effects of ocean acidification on the behaviour of fish vary from very larg... Read More about Acidification can directly affect olfaction in marine organisms.

Ocean Acidification Amplifies the Olfactory Response to 2-Phenylethylamine: Altered Cue Reception as a Mechanistic Pathway? (2021)
Journal Article
Hardege, J. D., Schirrmacher, P., Roggatz, C. C., & Benoit, D. M. (in press). Ocean Acidification Amplifies the Olfactory Response to 2-Phenylethylamine: Altered Cue Reception as a Mechanistic Pathway?. Journal of Chemical Ecology, https://doi.org/10.1007/s10886-021-01276-9

With carbon dioxide (CO2) levels rising dramatically, climate change threatens marine environments. Due to increasing CO2 concentrations in the ocean, pH levels are expected to drop by 0.4 units by the end of the century. There is an urgent need to u... Read More about Ocean Acidification Amplifies the Olfactory Response to 2-Phenylethylamine: Altered Cue Reception as a Mechanistic Pathway?.

Uridine-5'-tri-phosphate is a candidate component of the soluble sex pheromone bouquet in a marine shrimp, Lysmata wurdemanni (2020)
Journal Article
Zhang, D., Liu, X., Harley, M. A., & Hardege, J. D. (2020). Uridine-5'-tri-phosphate is a candidate component of the soluble sex pheromone bouquet in a marine shrimp, Lysmata wurdemanni. Marine ecology progress series, 640, 139-146. https://doi.org/10.3354/meps13294

Characterisation of distance sex pheromones in decapods is challenging, although great efforts have been made in this field in the past 50 yr. In a previous study, we identified a component of the distance (soluble) sex pheromone bouquet of the peppe... Read More about Uridine-5'-tri-phosphate is a candidate component of the soluble sex pheromone bouquet in a marine shrimp, Lysmata wurdemanni.

Saxitoxin and tetrodotoxin bioavailability increases in future oceans (2019)
Journal Article
Roggatz, C. C., Fletcher, N., Benoit, D. M., Algar, A. C., Doroff, A., Wright, B., …Hardege, J. D. (2019). Saxitoxin and tetrodotoxin bioavailability increases in future oceans. Nature Climate Change, 9(11), 840-844. https://doi.org/10.1038/s41558-019-0589-3

© 2019, The Author(s), under exclusive licence to Springer Nature Limited. Increasing atmospheric CO2 levels are largely absorbed by the ocean, decreasing surface water pH1. In combination with increasing ocean temperatures, these changes have been i... Read More about Saxitoxin and tetrodotoxin bioavailability increases in future oceans.

Short-and medium-term exposure to ocean acidification reduces olfactory sensitivity in gilthead seabream (2019)
Journal Article
Velez, Z., Roggatz, C. C., Benoit, D. M., Hardege, J., & Hubbard, P. C. (2019). Short-and medium-term exposure to ocean acidification reduces olfactory sensitivity in gilthead seabream. Frontiers in Physiology, 10, Article 731. https://doi.org/10.3389/fphys.2019.00731

The effects of ocean acidification on fish are only partially understood. Studies on olfaction are mostly limited to behavioural alterations of coral reef fish; studies on temperate species and/or with economic importance are scarce. The current stu... Read More about Short-and medium-term exposure to ocean acidification reduces olfactory sensitivity in gilthead seabream.

Free-sustaining three-dimensional S235 steel-based porous electrocatalyst for highly efficient and durable oxygen evolution (2018)
Journal Article
Han, W., Kuepper, K., Hou, P., Akram, W., Eickmeier, H., Hardege, J., …Schäfer, H. (2018). Free-sustaining three-dimensional S235 steel-based porous electrocatalyst for highly efficient and durable oxygen evolution. ChemSusChem, 11(20), 3661-3671. https://doi.org/10.1002/cssc.201801351

A novel oxygen evolution reaction (OER) catalyst (3D S235-P steel) based on steel S235 substrate has been successfully prepared via a facile one-step surface modification. The standard Carbon Manganese steel was phosphorizated superficially leading t... Read More about Free-sustaining three-dimensional S235 steel-based porous electrocatalyst for highly efficient and durable oxygen evolution.

Target gene expression studies on Platynereis dumerilii and Platynereis cfr massiliensis at the shallow CO2 vents off Ischia, Italy (2017)
Journal Article
Wäge, J., Rotchell, J. M., Gambi, M., & Hardege, J. D. (2018). Target gene expression studies on Platynereis dumerilii and Platynereis cfr massiliensis at the shallow CO2 vents off Ischia, Italy. Estuarine, coastal and shelf science, 207, 351-358. https://doi.org/10.1016/j.ecss.2017.11.012

© 2017 Elsevier Ltd Many studies predict negative effects of ocean acidification on marine organisms, potentially leading to loss of biodiversity and ecosystem function. Research on species inhabiting naturally high pCO2 environments, such as volcani... Read More about Target gene expression studies on Platynereis dumerilii and Platynereis cfr massiliensis at the shallow CO2 vents off Ischia, Italy.

The sibling polychaetes Platynereis dumerilii and Platynereis massiliensis in the Mediterranean Sea: are phylogeographic patterns related to exposure to ocean acidification? (2017)
Journal Article
Wäge, J., Valvassori, G., Hardege, J. D., Schulze, A., & Gambi, M. C. (2017). The sibling polychaetes Platynereis dumerilii and Platynereis massiliensis in the Mediterranean Sea: are phylogeographic patterns related to exposure to ocean acidification?. Marine Biology, 164(10), Article 199. https://doi.org/10.1007/s00227-017-3222-x

High pCO2 environments, such as volcanic carbon dioxide (CO2) vents, which mimic predicted near-future scenarios of ocean acidification (OA), offer an opportunity to examine effects of low pH conditions on marine biodiversity and adaptation/acclimati... Read More about The sibling polychaetes Platynereis dumerilii and Platynereis massiliensis in the Mediterranean Sea: are phylogeographic patterns related to exposure to ocean acidification?.

Cyanobacteria and microcystin contamination in untreated and treated drinking water in Ghana (2017)
Journal Article
Addico, G. N. D., Hardege, J. D., Kohoutek, J., DeGraft-Johnson, K. A. A., & Babica, P. (2017). Cyanobacteria and microcystin contamination in untreated and treated drinking water in Ghana. Advances in oceanography and limnology, 8(1), https://doi.org/10.4081/aiol.2017.6323

© 2017, Page Press Publications. All rights reserved. Although cyanobacterial blooms and cyanotoxins represent a worldwide-occurring phenomenon, there are large differences among different countries in cyanotoxin-related human health risk assessment,... Read More about Cyanobacteria and microcystin contamination in untreated and treated drinking water in Ghana.

Electro-oxidation of Ni42 steel: A highly active bifunctional electrocatalyst (2016)
Journal Article
Schäfer, H., Chevrier, D. M., Zhang, P., Stangl, J., Müller-Buschbaum, K., Hardege, J. D., …Schmidt, M. (2016). Electro-oxidation of Ni42 steel: A highly active bifunctional electrocatalyst. Advanced Functional Materials, 26(35), 6402-6417. https://doi.org/10.1002/adfm.201601581

Janus type water‐splitting catalysts have attracted highest attention as a tool of choice for solar to fuel conversion. AISI Ni42 steel is upon harsh anodization converted into a bifunctional electrocatalyst. Oxygen evolution reaction (OER) and hydro... Read More about Electro-oxidation of Ni42 steel: A highly active bifunctional electrocatalyst.

Short-term effects of CO₂-induced low pH exposure on target gene expression in Platynereis dumerilii (2016)
Journal Article
Wäge, J., Rohr, S., Hardege, J. D., & Rotchell, J. M. (2016). Short-term effects of CO₂-induced low pH exposure on target gene expression in Platynereis dumerilii. Journal of Marine Biology and Oceanography, 5(2), https://doi.org/10.4172/2324-8661.1000155

Objective: Increasing atmospheric CO₂ concentration are causing changes to the seawater carbonate chemistry, lowering the pH and we study potential impacts of these changes at the molecular level in a non-calcifying, marine polychaete species Platyne... Read More about Short-term effects of CO₂-induced low pH exposure on target gene expression in Platynereis dumerilii.

Ocean acidification affects marine chemical communication by changing structure and function of peptide signalling molecules (2016)
Journal Article
Roggatz, C. C., Lorch, M., Hardege, J. D., & Benoit, D. M. (2016). Ocean acidification affects marine chemical communication by changing structure and function of peptide signalling molecules. Global change biology, 22(12), 3914-3926. https://doi.org/10.1111/gcb.13354

Ocean acidification is a global challenge that faces marine organisms in the near future with a predicted rapid drop in pH of up to 0.4 units by the end of this century. Effects of the change in ocean carbon chemistry and pH on the development, growt... Read More about Ocean acidification affects marine chemical communication by changing structure and function of peptide signalling molecules.

Seizure control by decanoic acid through direct AMPA receptor inhibition (2015)
Journal Article
Chang, P., Augustin, K., Boddum, K., Williams, S., Sun, M., Terschak, J. A., …Williams, R. S. (2016). Seizure control by decanoic acid through direct AMPA receptor inhibition. Brain, 139(2), 431-443. https://doi.org/10.1093/brain/awv325

The medium chain triglyceride ketogenic diet is an established treatment for drug-resistant epilepsy that increases plasma levels of decanoic acid and ketones. Recently, decanoic acid has been shown to provide seizure control in vivo, yet its mechani... Read More about Seizure control by decanoic acid through direct AMPA receptor inhibition.

Exposure to low pH induces molecular level changes in the marine worm, Platynereis dumerilii (2015)
Journal Article
Wäge, J., Lerebours, A., Hardege, J. D., & Rotchell, J. M. (2016). Exposure to low pH induces molecular level changes in the marine worm, Platynereis dumerilii. Ecotoxicology and environmental safety, 124(February), 105-110. https://doi.org/10.1016/j.ecoenv.2015.10.008

© 2015 Elsevier Inc. Fossil fuel emissions and changes in net land use lead to an increase in atmospheric CO 2 concentration and a subsequent decrease of ocean pH. Noticeable effects on organisms' calcification rate, shell structure and energy metabo... Read More about Exposure to low pH induces molecular level changes in the marine worm, Platynereis dumerilii.

Oxidized mild steel S235: an efficient anode for the electrocatalytically initiated water-splitting (2015)
Journal Article
Schäfer, H., Küpper, K., Wollschläger, J., Kashaev, N., Hardege, J., Walder, L., …Dorn, F. (2015). Oxidized mild steel S235: an efficient anode for the electrocatalytically initiated water-splitting. ChemSusChem, 8(18), 3099-3110. https://doi.org/10.1002/cssc.201500666

The surface of steel S235 was oxidized by Cl₂ gas and checked for its electrocatalytic efficiency regarding oxygen formation in aqueous solution. If exposed to humid Cl₂ gas for 110 min, steel S235 became an electrocatalyst that exhibits an overpoten... Read More about Oxidized mild steel S235: an efficient anode for the electrocatalytically initiated water-splitting.

Stainless steel made to rust: a robust water-splitting catalyst with benchmark characteristics (2015)
Journal Article
Schäfer, H., Sadaf, S., Walder, L., Kuepper, K., Dinklage, S., Wollschläger, J., …Daum, D. (2015). Stainless steel made to rust: a robust water-splitting catalyst with benchmark characteristics. Energy & environmental science, 8(9), 2685-2697. https://doi.org/10.1039/c5ee01601k

The oxygen evolution reaction (OER) is known as the efficiency-limiting step for the electrochemical cleavage of water mainly due to the large overpotentials commonly used materials on the anode side cause. Since Ni–Fe oxides reduce overpotentials oc... Read More about Stainless steel made to rust: a robust water-splitting catalyst with benchmark characteristics.

Effects of low seawater pH on the marine polychaete Platynereis dumerilii (2015)
Journal Article
Wäge, J., Hardege, J. D., Larsson, T. A., Simakov, O., Chapman, E. C., Arendt, D., & Rotchell, J. M. (2015). Effects of low seawater pH on the marine polychaete Platynereis dumerilii. Marine pollution bulletin, 95(1), 166-172. https://doi.org/10.1016/j.marpolbul.2015.04.027

An important priority for any organism is to maintain internal cellular homeostasis including acidbase balance. Yet, the molecular level impacts of changing environmental conditions, such as low pH, remain uncharacterised. Herein, we isolate partial... Read More about Effects of low seawater pH on the marine polychaete Platynereis dumerilii.

Adaptation and acclimatization to ocean acidification in marine ectotherms: an in situ transplant experiment with polychaetes at a shallow CO₂ vent system (2013)
Journal Article
Calosi, P., Rastrick, S. P., Lombardi, C., de Guzman, H. J., Davidson, L., Jahnke, M., …Gambi, M. C. (2013). Adaptation and acclimatization to ocean acidification in marine ectotherms: an in situ transplant experiment with polychaetes at a shallow CO₂ vent system. Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 368(1627), 0-0. https://doi.org/10.1098/rstb.2012.0444

Metabolic rate determines the physiological and life-history performances of ectotherms. Thus, the extent to which such rates are sensitive and plastic to environmental perturbation is central to an organism's ability to function in a changing enviro... Read More about Adaptation and acclimatization to ocean acidification in marine ectotherms: an in situ transplant experiment with polychaetes at a shallow CO₂ vent system.

Divergence of scent pheromones in allopatric populations of Acanthodactylus boskianus (Squamata: Lacertidae) (2013)
Journal Article
Khannoon, E. R., Lunt, D. H., Schulz, S., & Hardege, J. (2013). Divergence of scent pheromones in allopatric populations of Acanthodactylus boskianus (Squamata: Lacertidae). Zoological Science, 30(5), 380-385. https://doi.org/10.2108/zsj.30.380

The evolutionary phenomena associated with divergence in chemical signals between populations of the same species help to understand the process of speciation. Animals detect and react to semiochemicals and pheromones used in communication. Compariso... Read More about Divergence of scent pheromones in allopatric populations of Acanthodactylus boskianus (Squamata: Lacertidae).

Identification of a female sex pheromone in Carcinus maenas (2011)
Journal Article
Hardege, J. D., Bartels-Hardege, H. D., Fletcher, N., Terschak, J. A., Harley, M., Smith, M. A., …Bublitz, R. (2011). Identification of a female sex pheromone in Carcinus maenas. Marine ecology progress series, 436, 177-189. https://doi.org/10.3354/meps09226

Despite major progress in our understanding of animal signaling systems, the identification of chemical signals in aquatic organisms is still in its infancy. Exemplary for this is the lack of structural knowledge of crustacean sex pheromones despite... Read More about Identification of a female sex pheromone in Carcinus maenas.

Analytical challenges and the development of biomarkers to measure and to monitor the effects of ocean acidification (2011)
Journal Article
Hardege, J., Rotchell, J., Terschak, J., & Greenway, G. (2011). Analytical challenges and the development of biomarkers to measure and to monitor the effects of ocean acidification. Trends in Analytical Chemistry, 30(8), 1320-1326. https://doi.org/10.1016/j.trac.2011.07.004

Changing ocean-carbonate chemistry caused by oceanic uptake of anthropogenic atmospheric carbon dioxide leads to the formation of carbonic acid, thus lowering the pH of the sea with predictions of a decrease from current levels at 8.15 to 7.82 by the... Read More about Analytical challenges and the development of biomarkers to measure and to monitor the effects of ocean acidification.

Simultaneously hermaphroditic shrimp use lipophilic cuticular hydrocarbons as contact sex pheromones (2011)
Journal Article
Hardege, J. D., Harley, M. A., Lin, J., Terschak, J. A., & Zhang, D. (2011). Simultaneously hermaphroditic shrimp use lipophilic cuticular hydrocarbons as contact sex pheromones. PLoS ONE, 6(4), e17720. https://doi.org/10.1371/journal.pone.0017720

Successful mating is essentially a consequence of making the right choices at the correct time. Animals use specific strategies to gain information about a potential mate, which is then applied to decision-making processes. Amongst the many informati... Read More about Simultaneously hermaphroditic shrimp use lipophilic cuticular hydrocarbons as contact sex pheromones.

The fecal odor of sick hedgehogs (Erinaceus europaeus) mediates olfactory attraction of the tick Ixodes hexagonus (2011)
Journal Article
Bunnell, T., Hanisch, K., Hardege, J. D., & Breithaupt, T. (2011). The fecal odor of sick hedgehogs (Erinaceus europaeus) mediates olfactory attraction of the tick Ixodes hexagonus. Journal of Chemical Ecology, 37(4), 340-347. https://doi.org/10.1007/s10886-011-9936-1

Parasite loads of animals vary among individuals, but the underlying mechanisms have not been fully identified. Here, we investigated whether health status of hedgehogs (Erinaceus europaeus) is correlated with tick burden, and whether chemical cues l... Read More about The fecal odor of sick hedgehogs (Erinaceus europaeus) mediates olfactory attraction of the tick Ixodes hexagonus.

New compounds, sexual differences, and age-related variations in the femoral gland secretions of the lacertid lizard Acanthodactylus boskianus (2011)
Journal Article
Khannoon, E. R., Flachsbarth, B., El-Gendy, A., Mazik, K., Hardege, J. D., & Schulz, S. (2011). New compounds, sexual differences, and age-related variations in the femoral gland secretions of the lacertid lizard Acanthodactylus boskianus. Biochemical Systematics and Ecology, 39(2), 95-101. https://doi.org/10.1016/j.bse.2011.01.008

Integumental gland secretions in lizards have been postulated to play a role as semiochemicals, but few studies have analysed the chemical nature of the gland secretions used in communication. We analysed the femoral gland secretions of Acanthodactyl... Read More about New compounds, sexual differences, and age-related variations in the femoral gland secretions of the lacertid lizard Acanthodactylus boskianus.

Biological responses to contaminants in the Humber Estuary: disentangling complex relationships (2011)
Journal Article
García-Alonso, J., Greenway, G., Munshi, A., Gómez, J., Mazik, K., Knight, A. W., …Elliott, M. (2011). Biological responses to contaminants in the Humber Estuary: disentangling complex relationships. Marine environmental research, 71(4), 295-303. https://doi.org/10.1016/j.marenvres.2011.02.004

Due to the ecological importance of estuaries, it is necessary to understand the biological effects that potentially toxic contaminants induce in bioindicator species. A key aspect is whether effects at lower levels of biological organisation transfe... Read More about Biological responses to contaminants in the Humber Estuary: disentangling complex relationships.

Evidence that 1-methyl-L-tryptophan is a food-related odorant for the Senegalese sole (Solea senegalensis) (2011)
Journal Article
Velez, Z., Hubbard, P. C., Hardege, J. D., Welham, K. J., Barata, E. N., & Canário, A. V. M. (2011). Evidence that 1-methyl-L-tryptophan is a food-related odorant for the Senegalese sole (Solea senegalensis). Aquaculture, 314(1-4), 153-158. https://doi.org/10.1016/j.aquaculture.2011.01.025

Nocturnal animals often rely heavily on olfactory cues to locate their food. This is especially true for fish whose prey live buried in the substrate. The aim of the current study was to identify non-polar odorants released by the ragworm (Hediste di... Read More about Evidence that 1-methyl-L-tryptophan is a food-related odorant for the Senegalese sole (Solea senegalensis).

Microscreening toxicity system based on living magnetic yeast and gradient chips (2010)
Journal Article
García-Alonso, J., Fakhrullin, R. F., Paunov, V. N., Shen, Z., Hardege, J. D., Pamme, N., …Greenway, G. M. (2011). Microscreening toxicity system based on living magnetic yeast and gradient chips. Analytical and Bioanalytical Chemistry, 400(4), 1009-1013. https://doi.org/10.1007/s00216-010-4241-3

There is an increasing demand for easy and cost-effective methods to screen the toxicological impact of the growing number of chemical mixtures being generated by industry. Such a screening method has been developed using viable, genetically modified... Read More about Microscreening toxicity system based on living magnetic yeast and gradient chips.

Experience matters: Females use smell to select experienced males for paternal care (2009)
Journal Article
Fletcher, N., Storey, E. J., Johnson, M., Reish, D. J., & Hardege, J. D. (2009). Experience matters: Females use smell to select experienced males for paternal care. PLoS ONE, 4(11), e7672. https://doi.org/10.1371/journal.pone.0007672

Mate choice and mating preferences often rely on the information content of signals exchanged between potential partners. In species where a female's reproduction is the terminal event in life it is to be expected that females choose high quality mal... Read More about Experience matters: Females use smell to select experienced males for paternal care.

Characterization of a sex pheromone in a simultaneous hermaphroditic shrimp, Lysmata wurdemanni (2009)
Journal Article
Zhang, D., Lin, J., Harley, M., & Hardege, J. D. (2010). Characterization of a sex pheromone in a simultaneous hermaphroditic shrimp, Lysmata wurdemanni. Marine Biology, 157(1), 1-6. https://doi.org/10.1007/s00227-009-1290-2

Olfactory chemical cues have been described to play important roles in the control of mate recognition in many decapod crustaceans. However, we still know very little about the chemical characteristics of the cues that coordinate pre-copulative behav... Read More about Characterization of a sex pheromone in a simultaneous hermaphroditic shrimp, Lysmata wurdemanni.

Identification, release and olfactory detection of bile salts in the intestinal fluid of the Senegalese sole (Solea senegalensis) (2009)
Journal Article
Velez, Z., Hubbard, P. C., Welham, K., Hardege, J., Barata, E. N., & Canário, A. V. M. (2009). Identification, release and olfactory detection of bile salts in the intestinal fluid of the Senegalese sole (Solea senegalensis). Journal of comparative physiology. A, Sensory, neural, and behavioral physiology, 195(7), 691-698. https://doi.org/10.1007/s00359-009-0444-5

Olfactory sensitivity to bile salts is wide-spread in teleosts; however, which bile salts are released in sufficient quantities to be detected is unclear. The current study identified bile salts in the intestinal and bile fluids of Solea senegalensis... Read More about Identification, release and olfactory detection of bile salts in the intestinal fluid of the Senegalese sole (Solea senegalensis).

The cost of conflict: agonistic encounters influence responses to chemical signals in the European shore crab (2008)
Journal Article
Fletcher, N., & Hardege, J. D. (2009). The cost of conflict: agonistic encounters influence responses to chemical signals in the European shore crab. Animal behaviour, 77(2), 357-361. https://doi.org/10.1016/j.anbehav.2008.10.007

The determination of an individual's behaviour often relies upon complex signals that convey messages about the environment it inhabits. In aquatic environments such signals take varied and conflicting forms including chemical cues indicating food or... Read More about The cost of conflict: agonistic encounters influence responses to chemical signals in the European shore crab.

Interspecific activity of the sex pheromone of the European shore crab (Carcinus maenas) (2008)
Journal Article
Bublitz, R., Sainte-Marie, B., Newcomb-Hodgetts, C., Fletcher, N., Smith, M., & Hardege, J. (2008). Interspecific activity of the sex pheromone of the European shore crab (Carcinus maenas). Behaviour, 145(10), 1465-1478. https://doi.org/10.1163/156853908785765872

The recent identification of uridine diphosphate (UDP) as the female sex-pheromone in the European shore crab Carcinus maenas demonstrated not only the link between moult and pheromone production, but also how it may have evolved from a 'simple' meta... Read More about Interspecific activity of the sex pheromone of the European shore crab (Carcinus maenas).

A prototype microfluidic chip using fluorescent yeast for detection of toxic compounds (2008)
Journal Article
García-Alonso, J., Greenway, G. M., Hardege, J. D., & Haswell, S. J. (2009). A prototype microfluidic chip using fluorescent yeast for detection of toxic compounds. Biosensors & bioelectronics, 24(5), 1508-1511. https://doi.org/10.1016/j.bios.2008.07.074

A microfluidic chip has been developed to enable the screening of chemicals for environmental toxicity. The microfluidic approach offers several advantages over macro-scale systems for toxicity screening, including low cost and flexibility in design.... Read More about A prototype microfluidic chip using fluorescent yeast for detection of toxic compounds.

Finding females: pheromone-guided reproductive tracking behavior by male Nereis succinea in the marine environment (2008)
Journal Article
Ram, J. L., Fei, X., Danaher, S. M., Lu, S., Breithaupt, T., & Hardege, J. D. (2008). Finding females: pheromone-guided reproductive tracking behavior by male Nereis succinea in the marine environment. The journal of experimental biology, 211(5), 757-765. https://doi.org/10.1242/jeb.012773

Pheromones trigger reproductive responses of many marine organisms, but little is known about how pheromones mediate mate-finding behavior in the marine environment. This paper investigates whether the tetrapeptide nereithione (cysteine-glutathione d... Read More about Finding females: pheromone-guided reproductive tracking behavior by male Nereis succinea in the marine environment.

Sex-specific mediation of foraging in the shore crab, Carcinus maenas (2007)
Journal Article
Hayden, D., Jennings, A., Müller, C., Pascoe, D., Bublitz, R., Webb, H., …Hardege, J. (2007). Sex-specific mediation of foraging in the shore crab, Carcinus maenas. Hormones and Behavior, 52(2), 162-168. https://doi.org/10.1016/j.yhbeh.2007.03.004

Experiments were conducted to investigate the sex-specific differences to feeding responses of the shore crab Carcinus maenas throughout the year. Results demonstrate that female shore crabs exhibit stronger feeding responses than males throughout th... Read More about Sex-specific mediation of foraging in the shore crab, Carcinus maenas.