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Outputs (140)

Impact of Exercise Training Response on Quality of Life and Cardiovascular Risk Factor Profiles in People with Coronary Artery Disease: Insights from the HIIT or MISS UK trial (2024)
Journal Article
Ingle, L., Powell, R., Begg, B., Birkett, S., Nichols, S., Ennis, S., …McGregor, G. (in press). Impact of Exercise Training Response on Quality of Life and Cardiovascular Risk Factor Profiles in People with Coronary Artery Disease: Insights from the HIIT or MISS UK trial. Archives of physical medicine and rehabilitation, https://doi.org/10.1016/j.apmr.2024.03.002

Objective: To compare the characteristics of “responders” and “non-responders” to 8-weeks of exercise training to determine differences in key cardiovascular disease outcomes in people with coronary artery disease (CAD). Design: Secondary analysis o... Read More about Impact of Exercise Training Response on Quality of Life and Cardiovascular Risk Factor Profiles in People with Coronary Artery Disease: Insights from the HIIT or MISS UK trial.

Inter- and Intra-Observer Reliability and Agreement of O2Pulse Inflection during Cardiopulmonary Exercise Testing: A Comparison of Subjective and Novel Objective Methodology (2024)
Journal Article
Nickolay, T., McGregor, G., Powell, R., Begg, B., Birkett, S., Nichols, S., …Ingle, L. (2024). Inter- and Intra-Observer Reliability and Agreement of O2Pulse Inflection during Cardiopulmonary Exercise Testing: A Comparison of Subjective and Novel Objective Methodology. PLoS ONE, 19(3), Article e0299486. https://doi.org/10.1371/journal.pone.0299486

Cardiopulmonary exercise testing (CPET) is the ‘gold standard’ method for evaluating functional capacity, with oxygen pulse (O2Pulse) inflections serving as a potential indicator of myocardial ischaemia. However, the reliability and agreement of iden... Read More about Inter- and Intra-Observer Reliability and Agreement of O2Pulse Inflection during Cardiopulmonary Exercise Testing: A Comparison of Subjective and Novel Objective Methodology.

High INtensity Interval Training In pATiEnts with intermittent claudication (INITIATE): a qualitative acceptability study (2024)
Journal Article
Pymer, S., Harwood, A., Ibeggazene, S., McGregor, G., Huang, C., Nicholls, A., …Twiddy, M. (2024). High INtensity Interval Training In pATiEnts with intermittent claudication (INITIATE): a qualitative acceptability study. Annals of vascular surgery, 102, Article 17-24. https://doi.org/10.1016/j.avsg.2023.11.043

Introduction A novel high-intensity interval training (HIIT) programme has demonstrated feasibility for patients with intermittent claudication (IC). The aim of this study was to explore patient perspectives of the HIIT programme to inform refinemen... Read More about High INtensity Interval Training In pATiEnts with intermittent claudication (INITIATE): a qualitative acceptability study.

High-intensity interval training in patients with intermittent claudication (2023)
Journal Article
Pymer, S., Harwood, A. E., Prosser, J., Waddell, A., Rhavindhran, B., McGregor, G., …Chetter, I. C. (2023). High-intensity interval training in patients with intermittent claudication. Journal of vascular surgery, 78(4), 1048-1056.e4. https://doi.org/10.1016/j.jvs.2023.05.045

Objective: Provision, uptake, adherence, and completion rates for supervised exercise programs (SEP) for intermittent claudication (IC) are low. A shorter, more time-efficient, 6-week, high-intensity interval training (HIIT) program may be an effecti... Read More about High-intensity interval training in patients with intermittent claudication.

A randomised controlled, feasibility study to establish the acceptability of early outpatient review and early cardiac rehabilitation compared to standard practice after cardiac surgery and viability of a future large-scale trial (FARSTER) (2023)
Journal Article
Ngaage, D., Mitchell, N., Dean, A., Mitchell, A., Hinde, S., Akowuah, E., …Watson, J. (2023). A randomised controlled, feasibility study to establish the acceptability of early outpatient review and early cardiac rehabilitation compared to standard practice after cardiac surgery and viability of a future large-scale trial (FARSTER). Pilot and Feasibility Studies, 9(1), Article 79. https://doi.org/10.1186/s40814-023-01304-3

Objective: To determine the acceptability and feasibility of delivering early outpatient review following cardiac surgery and early cardiac rehabilitation (CR), compared to standard practice to establish if a future large-scale trial is achievable. M... Read More about A randomised controlled, feasibility study to establish the acceptability of early outpatient review and early cardiac rehabilitation compared to standard practice after cardiac surgery and viability of a future large-scale trial (FARSTER).

Serum transthyretin and aminotransferases are associated with lean mass in people with coronary heart disease: Further insights from the CARE-CR study (2023)
Journal Article
James, E., Goodall, S., Nichols, S., Walker, K., Carroll, S., O’Doherty, A. F., & Ingle, L. (2023). Serum transthyretin and aminotransferases are associated with lean mass in people with coronary heart disease: Further insights from the CARE-CR study. Frontiers in Medicine, 10, Article 1094733. https://doi.org/10.3389/fmed.2023.1094733

Background: Low muscle mass disproportionately affects people with coronary heart disease compared to healthy controls but is under-researched and insufficiently treated. Inflammation, poor nutrition, and neural decline might contribute to low muscle... Read More about Serum transthyretin and aminotransferases are associated with lean mass in people with coronary heart disease: Further insights from the CARE-CR study.

High-intensity interval training in cardiac rehabilitation: a multi-centre randomized controlled trial (2023)
Journal Article
McGregor, G., Powell, R., Begg, B., Birkett, S. T., Nichols, S., Ennis, S., …Shave, R. (2023). High-intensity interval training in cardiac rehabilitation: a multi-centre randomized controlled trial. European Journal of Preventive Cardiology, 30(9), 745-755. https://doi.org/10.1093/eurjpc/zwad039

BACKGROUND: There is a lack of international consensus regarding the prescription of high-intensity interval training (HIIT) for people with coronary artery disease (CAD) attending cardiac rehabilitation (CR). AIMS: To assess the clinical effectivene... Read More about High-intensity interval training in cardiac rehabilitation: a multi-centre randomized controlled trial.

Effects of exercise prescribed at different levels of claudication pain on walking performance in patients with intermittent claudication: a protocol for a randomised controlled trial (2022)
Journal Article
Birkett, S., Sinclair, J., Seed, S., Pymer, S., Caldow, E., Ingle, L., …Egun, A. (2022). Effects of exercise prescribed at different levels of claudication pain on walking performance in patients with intermittent claudication: a protocol for a randomised controlled trial. Therapeutic Advances in Cardiovascular Disease, 16, https://doi.org/10.1177/17539447221108817

Background: Peripheral artery disease affects over 236 million people globally and the classic symptom is intermittent claudication (IC) which is associated with reduction in physical activity. The evidence that supervised exercise programmes (SEPs)... Read More about Effects of exercise prescribed at different levels of claudication pain on walking performance in patients with intermittent claudication: a protocol for a randomised controlled trial.

Substituting bouts of sedentary behavior with physical activity: adopting positive lifestyle choices in people with a history of cancer (2022)
Journal Article
Ingle, L., Ruilova, S., Cui, Y., DeClercq, V., Sweeney, E., Yu, Z. M., & Forbes, C. C. (2022). Substituting bouts of sedentary behavior with physical activity: adopting positive lifestyle choices in people with a history of cancer. Cancer Causes and Control, https://doi.org/10.1007/s10552-022-01592-9

Purpose: To determine in people with a history of cancer, whether substituting sitting time with other daily activities (i.e., sleeping, walking, moderate and vigorous physical activity) was associated with changes in waist circumference (WC), an imp... Read More about Substituting bouts of sedentary behavior with physical activity: adopting positive lifestyle choices in people with a history of cancer.

Validity and reliability of the movement assessment battery second edition test in children with and without motor impairment: A prospective cohort study (2022)
Journal Article
Ghayour Najafabadi, M., Saghaei, B., Shariat, A., Ingle, L., Babazadeh-Zavieh, S. S., Shojaei, M., & Daneshfar, A. (2022). Validity and reliability of the movement assessment battery second edition test in children with and without motor impairment: A prospective cohort study. Annals of Medicine and Surgery, 77, Article 103672. https://doi.org/10.1016/j.amsu.2022.103672

Background: Examining the reliability and validity of the second edition movement assessment battery test (MABC-2) in children with and without motor impairment. Materials and methods: In this prospective cohort study, the MABC-2 test and development... Read More about Validity and reliability of the movement assessment battery second edition test in children with and without motor impairment: A prospective cohort study.

A pilot study examining the safety and effectiveness of 8-weeks of early cardiac rehabilitation on physical function and psychological well-being in patients following aortic root replacement (2022)
Journal Article
Najafabadi, M., Niazi, S., Mortazavian, S., Khah, A., & Ingle, L. (2022). A pilot study examining the safety and effectiveness of 8-weeks of early cardiac rehabilitation on physical function and psychological well-being in patients following aortic root replacement. Physiotherapy Practice and Research, 43(1), 37-43. https://doi.org/10.3233/PPR-210541

AIM: To determine the effects of a structured, moderate-intensity, early cardiac rehabilitation (CR) program on physical function and psychological wellbeing in patients following aortic root replacement. MATERIALS AND METHODS: Patients were randomly... Read More about A pilot study examining the safety and effectiveness of 8-weeks of early cardiac rehabilitation on physical function and psychological well-being in patients following aortic root replacement.

Effects of aquatic therapy on balance in older adults: a systematic review and meta-analysis (2021)
Journal Article
Shariat, A., Ghayour Najafabadi, M., Ghannadi, S., Nakhostin-Ansari, A., Hakakzadeh, A., Shaw, B. S., …Cleland, J. A. (2021). Effects of aquatic therapy on balance in older adults: a systematic review and meta-analysis. European Geriatric Medicine, https://doi.org/10.1007/s41999-021-00577-2

Purpose: Balance is a key component of movement for daily activities, especially in older adults. Previous studies examining aquatic therapy as an effective way for improving balance have yielded inconsistent findings. The current systematic review a... Read More about Effects of aquatic therapy on balance in older adults: a systematic review and meta-analysis.

The Rating of Perceived Exertion at the Ventilatory Anaerobic Threshold in Patients with Coronary Heart Disease - Prescribing Implications for Exercise-Based Cardiovascular Rehabilitation: A CARE CR study (2021)
Journal Article
Nichols, S., Engin, B., Carroll, S., Buckley, J., & Ingle, L. (2021). The Rating of Perceived Exertion at the Ventilatory Anaerobic Threshold in Patients with Coronary Heart Disease - Prescribing Implications for Exercise-Based Cardiovascular Rehabilitation: A CARE CR study. Annals of physical and rehabilitation medicine, 64(6), Article 101462. https://doi.org/10.1016/j.rehab.2020.101462

Background: Exercise prescription guidelines for patients undertaking cardiovascular rehabilitation (CR) are based on heart rate training zones and ratings of perceived exertion (RPE). In the UK, guidelines indicate that patients should exercise at a... Read More about The Rating of Perceived Exertion at the Ventilatory Anaerobic Threshold in Patients with Coronary Heart Disease - Prescribing Implications for Exercise-Based Cardiovascular Rehabilitation: A CARE CR study.

Ratings of perceived exertion at the ventilatory anaerobic threshold in people with coronary heart disease: A CARE CR study (2021)
Journal Article
Nichols, S., Engin, B., Carroll, S., Buckley, J., & Ingle, L. (2021). Ratings of perceived exertion at the ventilatory anaerobic threshold in people with coronary heart disease: A CARE CR study. Annals of physical and rehabilitation medicine, 64(6), Article 101462. https://doi.org/10.1016/j.rehab.2020.101462

Background: Exercise prescription guidelines for individuals undergoing cardiovascular rehabilitation (CR) are often based on heart rate training zones and rating of perceived exertion (RPE). United Kingdom guidelines indicate that patients should ex... Read More about Ratings of perceived exertion at the ventilatory anaerobic threshold in people with coronary heart disease: A CARE CR study.

A Systematic Review of Exercise Prescription in Patients with Intermittent Claudication: Does Pain Matter? (2021)
Journal Article
Seed, S., Harwood, A., Sinclair, J., Pymer, S., Caldow, E., Ingle, L., …Birkett, S. (in press). A Systematic Review of Exercise Prescription in Patients with Intermittent Claudication: Does Pain Matter?. Annals of vascular surgery, https://doi.org/10.1016/j.avsg.2021.06.025

Background: Current guidelines for intermittent claudication advocate exercise at moderate to maximal claudication pain. However, adherence rates to supervised exercise programmes (SEP) remain poor and claudication pain is a contributing factor. Limi... Read More about A Systematic Review of Exercise Prescription in Patients with Intermittent Claudication: Does Pain Matter?.

The associations between physical activity intensity, cardiorespiratory fitness, and non-alcoholic fatty liver disease (2021)
Journal Article
Kerr, C., Waterworth, S., Brodie, D., Sandercock, G., & Ingle, L. (2021). The associations between physical activity intensity, cardiorespiratory fitness, and non-alcoholic fatty liver disease. Journal of Gastroenterology and Hepatology, 36(12), 3508-3514. https://doi.org/10.1111/jgh.15672

Background and Aim: High levels of physical activity and cardiorespiratory fitness may protect against non-alcoholic fatty liver disease. We investigated whether different physical activity intensities and cardiorespiratory fitness were independent p... Read More about The associations between physical activity intensity, cardiorespiratory fitness, and non-alcoholic fatty liver disease.

Provision of exercise services in patients with peripheral artery disease in the United Kingdom (2021)
Journal Article
Harwood, A. E., Pymer, S., Ibeggazene, S., Ingle, L., Caldow, E., & Birkett, S. T. (in press). Provision of exercise services in patients with peripheral artery disease in the United Kingdom. Vascular, https://doi.org/10.1177/17085381211035259

Objectives: Supervised exercise programmes (SEPs) are a vital treatment for people with intermittent claudication, leading improvements in walking distance and quality of life and are recommended in multiple national and international guidelines. We... Read More about Provision of exercise services in patients with peripheral artery disease in the United Kingdom.

Love is in the hair: arginine methylation of human hair proteins as novel cardiovascular biomarkers (2021)
Journal Article
Marsden, A. J., Riley, D. R., Birkett, S., Rodriguez-Barucg, Q., Guinn, B. A., Carroll, S., …Beltran-Alvarez, P. (in press). Love is in the hair: arginine methylation of human hair proteins as novel cardiovascular biomarkers. Amino acids, https://doi.org/10.1007/s00726-021-03024-5

Cardiovascular disease is the major cause of death worldwide. Extensive cardiovascular biomarkers are available using blood tests but very few, if any, investigations have described non-invasive tests for cardiovascular biomarkers based on readily av... Read More about Love is in the hair: arginine methylation of human hair proteins as novel cardiovascular biomarkers.

Aquatic Therapy for improving Lower Limbs Function in Post-stroke Survivors: A Systematic Review with Meta-Analysis (2021)
Journal Article
Ghayour Najafabadi, M., Shariat, A., Dommerholt, J., Hakakzadeh, A., Nakhostin-Ansari, A., Selk-Ghaffari, M., …Cleland, J. A. (in press). Aquatic Therapy for improving Lower Limbs Function in Post-stroke Survivors: A Systematic Review with Meta-Analysis. Topics in Stroke Rehabilitation, 1-17. https://doi.org/10.1080/10749357.2021.1929011

Background: Lower limb disability is common in chronic stroke patients, and aquatic therapy is one of the modalities used for the rehabilitation of these patients. Objectives: To summarize the evidence of the effects of aquatic therapy on lower limb... Read More about Aquatic Therapy for improving Lower Limbs Function in Post-stroke Survivors: A Systematic Review with Meta-Analysis.

An Updated Systematic Review and Meta-Analysis of Home-based Exercise Programmes for Individuals with Intermittent Claudication. (2021)
Journal Article
Pymer, S., Ibeggazene, S., Palmer, J., Tew, G., Ingle, L., Smith, G., …Harwood, A. (2021). An Updated Systematic Review and Meta-Analysis of Home-based Exercise Programmes for Individuals with Intermittent Claudication. Journal of vascular surgery, 74(6), 2076-2085.e20

Objectives: Supervised exercise programmes (SEP) are effective for improving walking distance in patients with intermittent claudication (IC) but provision and uptake rates are sub-optimal. Access to such programmes has also been halted by the Corona... Read More about An Updated Systematic Review and Meta-Analysis of Home-based Exercise Programmes for Individuals with Intermittent Claudication..

A systematic review of exercise testing in patients with intermittent claudication: A focus on test standardisation and reporting quality in randomised controlled trials of exercise interventions (2021)
Journal Article
Birkett, S., Harwood, A., Caldow, E., Ibeggazene, S., Ingle, L., & Pymer, S. (2021). A systematic review of exercise testing in patients with intermittent claudication: A focus on test standardisation and reporting quality in randomised controlled trials of exercise interventions. PLoS ONE, 16(5 May), Article e0249277. https://doi.org/10.1371/journal.pone.0249277

A systematic review was conducted to identify the range of terminology used in studies to describe maximum walking distance and the exercise testing protocols, and testing modalities used to measure it in patients with intermittent claudication. A se... Read More about A systematic review of exercise testing in patients with intermittent claudication: A focus on test standardisation and reporting quality in randomised controlled trials of exercise interventions.

A double-blind randomized controlled trial for the effects of dry needling on upper limb dysfunction in patients with stroke (2021)
Journal Article
Tavakol, Z., Shariat, A., Ansari, N., Ghannadi, S., Honarpishe, R., Dommerholt, J., …Ingle, L. (2021). A double-blind randomized controlled trial for the effects of dry needling on upper limb dysfunction in patients with stroke. Acupuncture and Electro-Therapeutics Research, 45(2-4), 115-124. https://doi.org/10.3727/036012921X16112663844923

Spasticity is one of the main complications of a stroke. This double-blind, randomized controlled trial aimed to compare the result of three sessions of dry needling (DN) versus sham DN on the affected upper limbs in post-stroke survivors. We recruit... Read More about A double-blind randomized controlled trial for the effects of dry needling on upper limb dysfunction in patients with stroke.

Sudden cardiac death in athletes: A mini-review (2020)
Journal Article
Soori, R., Gharehlo, A., Hashemi, N., Hashemi, N., & Ingle, L. (2020). Sudden cardiac death in athletes: A mini-review. World Heart Journal, 21(1), 71-76

Elite young athletes with clinically silent cardiovascular disorders are at risk of sudden cardiac death (SCD) in competitive sports activity. SCD is caused by a variety of conditions; in middle-aged/senior athletes, atherosclerotic coronary artery d... Read More about Sudden cardiac death in athletes: A mini-review.

Considering the feasibility, tolerability and safety of high intensity interval training as a novel treatment for patients with intermittent claudication (2020)
Journal Article
Pymer, S., Ibeggazene, S., Palmer, J., Smith, G. E., Carroll, S., Ingle, L., …Chetter, I. C. (2021). Considering the feasibility, tolerability and safety of high intensity interval training as a novel treatment for patients with intermittent claudication. Journal of Cardiopulmonary Rehabilitation and Prevention, 41(3), 188-193. https://doi.org/10.1097/HCR.0000000000000551

Considering the Feasibility, Tolerability and Safety of High-Intensity Interval Training as a Novel Treatment for Patients with Intermittent Claudication. Structured Abstract Purpose: This study assessed the feasibility, tolerability, safety and... Read More about Considering the feasibility, tolerability and safety of high intensity interval training as a novel treatment for patients with intermittent claudication.

Exercise training for intermittent claudication: A narrative review and summary of guidelines for practitioners (2020)
Journal Article
Harwood, A., Pymer, S., Ingle, L., Doherty, P., Chetter, I. C., Parmenter, B., …Tew, G. (2020). Exercise training for intermittent claudication: A narrative review and summary of guidelines for practitioners. BMJ Open Sport and Exercise Medicine, 6(1), Article e000897. https://doi.org/10.1136/bmjsem-2020-000897

Peripheral artery disease (PAD) is caused by atherosclerotic narrowing of the arteries supplying the lower limbs often resulting in intermittent claudication, evident as pain or cramping while walking. Supervised exercise training elicits clinically... Read More about Exercise training for intermittent claudication: A narrative review and summary of guidelines for practitioners.

Normative reference values for estimated cardiorespiratory fitness in apparently healthy British men and women (2020)
Journal Article
Ingle, L., Rigby, A., Brodie, D., & Sandercock, G. (2020). Normative reference values for estimated cardiorespiratory fitness in apparently healthy British men and women. PLoS ONE, 15(10), Article e0240099. https://doi.org/10.1371/journal.pone.0240099

Copyright: © 2020 Ingle et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and sour... Read More about Normative reference values for estimated cardiorespiratory fitness in apparently healthy British men and women.

Presurgery exercise-based conditioning interventions (prehabilitation) in adults undergoing lower limb surgery for peripheral arterial disease (Review) (2020)
Journal Article
Palmer, J., Pymer, S., Smith, G. E., Harwood, A., Ingle, L., Huang, C., & Chetter, I. C. (2020). Presurgery exercise-based conditioning interventions (prehabilitation) in adults undergoing lower limb surgery for peripheral arterial disease (Review). The Cochrane database of systematic reviews, 2020(9), Article CD013407. https://doi.org/10.1002/14651858.CD013407.pub2

Copyright © 2020 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd. Background: Lower limb peripheral arterial disease (PAD) is a type of cardiovascular disease where the blood vessels that carry the blood to the legs are hardened and... Read More about Presurgery exercise-based conditioning interventions (prehabilitation) in adults undergoing lower limb surgery for peripheral arterial disease (Review).

Presurgery exercise-based conditioning interventions (prehabilitation) in adults undergoing lower limb surgery for peripheral arterial disease. (2020)
Journal Article
Palmer, J., Pymer, S., Smith, G. E., Elizabeth Harwood, A., Ingle, L., Huang, C., & Chetter, I. C. (2020). Presurgery exercise-based conditioning interventions (prehabilitation) in adults undergoing lower limb surgery for peripheral arterial disease. Cochrane Database of Systematic Reviews, Article CD013407. https://doi.org/10.1002/14651858.CD013407.pub2

Background Lower limb peripheral arterial disease (PAD) is a type of cardiovascular disease where the blood vessels that carry the blood to the legs are hardened and narrowed. The most severe manifestation of PAD is critical limb ischaemia (CLI). Th... Read More about Presurgery exercise-based conditioning interventions (prehabilitation) in adults undergoing lower limb surgery for peripheral arterial disease..

Characterising the application of the “progressive overload” principle of exercise training within cardiac rehabilitation: a United Kingdom-based community programme (2020)
Journal Article
Khushhal, A., Nichols, S., Carroll, S., Abt, G., & Ingle, L. (in press). Characterising the application of the “progressive overload” principle of exercise training within cardiac rehabilitation: a United Kingdom-based community programme. PLoS ONE, 15(8), Article e0237197. https://doi.org/10.1371/journal.pone.0237197

BACKGROUND: Recent concerns have cast doubt over the effectiveness of cardiac rehabilitation [CR] programmes for improving cardiorespiratory fitness [CRF] in patients with a history of cardiac disease in the United Kingdom [UK]. We aimed to character... Read More about Characterising the application of the “progressive overload” principle of exercise training within cardiac rehabilitation: a United Kingdom-based community programme.

Current insights into exercise-based cardiac rehabilitation in patients with coronary heart disease and chronic heart failure (2020)
Journal Article
Nichols, S., McGregor, G., Breckon, J., & Ingle, L. (in press). Current insights into exercise-based cardiac rehabilitation in patients with coronary heart disease and chronic heart failure. International journal of sports medicine, https://doi.org/10.1055/a-1198-5573

Cardiac rehabilitation is a package of lifestyle secondary prevention strategies designed for patients with coronary heart disease and chronic heart failure. A community-based cardiac rehabilitation programme provides patients with a structured exerc... Read More about Current insights into exercise-based cardiac rehabilitation in patients with coronary heart disease and chronic heart failure.

high INtensity Interval Training In pATiEnts with intermittent claudication (INITIATE): protocol for a multi-centre, proof-of-concept, prospective interventional study (2020)
Journal Article
Pymer, S., Harwood, A., Ibeggazene, S., McGregor, G., Huang, C., Twiddy, M., …Chetter, I. C. (2020). high INtensity Interval Training In pATiEnts with intermittent claudication (INITIATE): protocol for a multi-centre, proof-of-concept, prospective interventional study. BMJ open, 10(7), Article e038825. https://doi.org/10.1136/bmjopen-2020-038825

Introduction: The first-line recommended treatment for patients with intermittent claudication (IC), is a supervised exercise programme (SEP), which includes a minimum of 2 hours exercise per week over a 12-week period. However, provision, uptake, an... Read More about high INtensity Interval Training In pATiEnts with intermittent claudication (INITIATE): protocol for a multi-centre, proof-of-concept, prospective interventional study.

The Effect of Dry Needling on Lower Limb Dysfunction in Poststroke Survivors (2020)
Journal Article
Ghannadi, S., Shariat, A., Ansari, N., Tavakol, Z., Honarpishe, R., Hakakzadeh, A., …Ingle, L. (2020). The Effect of Dry Needling on Lower Limb Dysfunction in Poststroke Survivors. Journal of Stroke and Cerebrovascular Diseases, 29(6), Article 104814. https://doi.org/10.1016/j.jstrokecerebrovasdis.2020.104814

Background: Spasticity is one of the main complications in poststroke survivors leading to difficulties in walking and standing resulting in high levels of disability. Objective: The aim of the study was to investigate the effects of deep dry needlin... Read More about The Effect of Dry Needling on Lower Limb Dysfunction in Poststroke Survivors.

Routine exercise-based cardiac rehabilitation does not increase aerobic fitness: A CARE CR study (2020)
Journal Article
Nichols, S., Taylor, C., Goodman, T., Page, R., Kallvikbacka-Bennett, A., Nation, F., …Ingle, L. (2020). Routine exercise-based cardiac rehabilitation does not increase aerobic fitness: A CARE CR study. International journal of cardiology, 305, 25-34. https://doi.org/10.1016/j.ijcard.2020.01.044

© 2020 The Authors Background: Recent evidence suggests that routine exercise-based cardiac rehabilitation (CR) may not lead to a substantial increase in estimated peak oxygen uptake (V̇O2peak). This could reduce the potential benefits of CR and expl... Read More about Routine exercise-based cardiac rehabilitation does not increase aerobic fitness: A CARE CR study.

A comprehensive screening protocol to identify incidence of lower back pain in military office workers (2020)
Journal Article
Alizadeh, R., Shariat, A., Hakakzadeh, A., Selk-Ghaffari, M., Damavandi, P., Honarpishe, R., & Ingle, L. (2020). A comprehensive screening protocol to identify incidence of lower back pain in military office workers. Journal of Pain Management, 13(1), 35-40

Military workers experience different types of lower back pain (LBP), but there is little evidence concerning the incidence of LBP in this group, especially in Asian countries. One of the most common forms of LBP is discogenic low back pain (DLBP) wh... Read More about A comprehensive screening protocol to identify incidence of lower back pain in military office workers.

Test–retest repeatability of the NX-16: a three-dimensional (3D) body scanner in a male cohort (2019)
Journal Article
Turpin, R. L., Douglas, C. C., Gleadall-Siddall, D. O., Turpin, R., Douglas, C., Ingle, L., & Garrett, A. T. (2020). Test–retest repeatability of the NX-16: a three-dimensional (3D) body scanner in a male cohort. Sport Sciences for Health, 16(2), 337-346. https://doi.org/10.1007/s11332-019-00611-8

© 2019, The Author(s). Purpose: Whole-body three-dimensional scanning is a tool utilised for the collection of body girths, volume, and surface area measurements. Few studies have investigated the validity and repeatability of this technology. The ai... Read More about Test–retest repeatability of the NX-16: a three-dimensional (3D) body scanner in a male cohort.

Concurrent impact of bilateral multiple joint functional electrical stimulation and treadmill walking on gait and spasticity in post-stroke survivors: a pilot study (2019)
Journal Article
Hakakzadeh, A., Shariat, A., Honarpishe, R., Moradi, V., Ghannadi, S., Sangelaji, B., …Ingle, L. (in press). Concurrent impact of bilateral multiple joint functional electrical stimulation and treadmill walking on gait and spasticity in post-stroke survivors: a pilot study. Physiotherapy theory and practice, https://doi.org/10.1080/09593985.2019.1685035

Background: Stroke causes multi-joint gait deficits, so a major objective of post-stroke rehabilitation is to regain normal gait function. Design and Setting: A case series completed at a neuroscience institute. Aim: The aim of the study was to deter... Read More about Concurrent impact of bilateral multiple joint functional electrical stimulation and treadmill walking on gait and spasticity in post-stroke survivors: a pilot study.

The impact of modified exercise and relaxation therapy on chronic lower back pain in office workers: a randomized clinical trial (2019)
Journal Article
Shaw, I., Shaw, B. S., Shariat, A., Alizadeh, R., Moradi, V., Afsharnia, E., …Ingle, L. (2019). The impact of modified exercise and relaxation therapy on chronic lower back pain in office workers: a randomized clinical trial. Journal of Exercise Rehabilitation, 15(5), 703-708. https://doi.org/10.12965/jer.1938490.245

This study aimed to evaluate the effectiveness of a modified package of exercise therapy combined with relaxation on pain intensity, range of motion (ROM), anxiety, and quality of life (QoL) in office workers with chronic lower back pain. In this cli... Read More about The impact of modified exercise and relaxation therapy on chronic lower back pain in office workers: a randomized clinical trial.

Multimodal impact of acupuncture, exercise therapy, and concurrent functional electrical stimulation on osteoarthritis of the knee: a case report (2019)
Journal Article
Hakakzadeh, A., Shariat, A., Moradi, V., Ingle, L., Honarpishe, R., Noormohammadpour, P., & Ansari, N. N. (2019). Multimodal impact of acupuncture, exercise therapy, and concurrent functional electrical stimulation on osteoarthritis of the knee: a case report. Acupuncture and Electro-Therapeutics Research, 44(2), 135-145. https://doi.org/10.3727/036012919X15650315071942

Knee osteoarthritis (OA) causes functional limitation in weight-bearing activities including walking. To investigate the multimodal impact of acupuncture, exercise therapy, and concurrent functional electrical stimulation (FES) on knee osteoarthritis... Read More about Multimodal impact of acupuncture, exercise therapy, and concurrent functional electrical stimulation on osteoarthritis of the knee: a case report.

Presurgery conditioning interventions (prehabilitation) in adults undergoing lower limb surgery for peripheral arterial disease (2019)
Journal Article
Palmer, J., Pymer, S., Smith, G. E., Harwood, A. E., Ingle, L., Huang, C., & Chetter, I. C. (2019). Presurgery conditioning interventions (prehabilitation) in adults undergoing lower limb surgery for peripheral arterial disease. The Cochrane database of systematic reviews, 2019(9), Article CD013407. https://doi.org/10.1002/14651858.cd013407

This is a protocol for a Cochrane Review (Intervention). The objectives are as follows: To assess the effectiveness of prehabilitation (preoperative exercise, either alone or in combination with nutritional or psychological interventions or both)... Read More about Presurgery conditioning interventions (prehabilitation) in adults undergoing lower limb surgery for peripheral arterial disease.

Effects of kinesiotaping on knee osteoarthritis: A literature review (2019)
Journal Article
Abolhasani, M., Moradi, V., Halabchi, F., Afsharnia, E., Ingle, L., Shariat, A., & Hakakzadeh, A. (2019). Effects of kinesiotaping on knee osteoarthritis: A literature review. Journal of Exercise Rehabilitation, 15(4), 498-503. https://doi.org/10.12965/jer.1938364.182

The purpose of this review was to determine the current evidence-base for the efficacy of kinesiotaping in patients with osteoarthritis. Search-ing was undertaken using MEDLINE, Embase, Scopus, Web of Science, Physiotherapy Evidence Database (PEDro)... Read More about Effects of kinesiotaping on knee osteoarthritis: A literature review.

Exercise training as a mediator for enhancing coronary collateral circulation: A review of the evidence (2019)
Journal Article
Nickolay, T., Nichols, S., Ingle, L., & Hoye, A. (2020). Exercise training as a mediator for enhancing coronary collateral circulation: A review of the evidence. Current Cardiology Reviews, 16(3), 212-220. https://doi.org/10.2174/1573403X15666190819144336

Coronary collateral vessels supply blood to areas of myocardium at risk after arterial occlusion. Flow through these channels is driven by a pressure gradient between the donor and the occluded artery. Concomitant with increased collateral flow is an... Read More about Exercise training as a mediator for enhancing coronary collateral circulation: A review of the evidence.

Quantification of exercise training dose in phase III cardiac rehabilitation : a UK perspective (2019)
Thesis
Khushhal, A. (2019). Quantification of exercise training dose in phase III cardiac rehabilitation : a UK perspective. (Thesis). University of Hull. Retrieved from https://hull-repository.worktribe.com/output/4222067

The Apple watch was a new technology first introduced in 2015. At that time, its validity and reliability for measuring stepping frequency and heart rate monitoring during exercise was unknown. Current evidence indicates that the effectiveness of car... Read More about Quantification of exercise training dose in phase III cardiac rehabilitation : a UK perspective.

Effect of intensive neuromuscular electrical stimulation on chronic neck pain: A case report (2019)
Journal Article
Ansari, N. N., Ingle, L., Tavakol, Z., Shariat, A., Ghannadi, S., Noureddin, N., …Haghighi, F. (2019). Effect of intensive neuromuscular electrical stimulation on chronic neck pain: A case report. Journal of Pain Management, 12(2), 173-177

© Nova Science Publishers, Inc. Chronic neck pain is a relatively common problem that can interfere with daily activities, and it is often experienced following musculoskeletal injuries. To identify the impact of intensive neuromuscular electrical st... Read More about Effect of intensive neuromuscular electrical stimulation on chronic neck pain: A case report.

A systematic review of high-intensity interval training as an exercise intervention for intermittent claudication (2019)
Journal Article
Pymer, S., Palmer, J., Harwood, A. E., Ingle, L., Smith, G. E., & Chetter, I. C. (2019). A systematic review of high-intensity interval training as an exercise intervention for intermittent claudication. Journal of vascular surgery, https://doi.org/10.1016/j.jvs.2019.03.050

Background Intermittent claudication (IC) is the most common symptom of peripheral arterial disease, which significantly affects walking ability, functional capacity and quality of life. Supervised exercise programs (SEP) are recommended as first-lin... Read More about A systematic review of high-intensity interval training as an exercise intervention for intermittent claudication.

Insufficient exercise intensity for clinical benefit? Monitoring and quantification of a community-based Phase III cardiac rehabilitation programme: A United Kingdom perspective (2019)
Journal Article
Khushhal, A., Nichols, S., Carroll, S., Abt, G., & Ingle, L. (in press). Insufficient exercise intensity for clinical benefit? Monitoring and quantification of a community-based Phase III cardiac rehabilitation programme: A United Kingdom perspective. PLoS ONE, 14(6), Article e0217654. https://doi.org/10.1371/journal.pone.0217654

Abstract: Background: In recent years, criticism of the percentage range approach for individualised exercise prescription has intensified and we were concerned that sub-optimal exercise dose (especially intensity) may be in part responsible for the... Read More about Insufficient exercise intensity for clinical benefit? Monitoring and quantification of a community-based Phase III cardiac rehabilitation programme: A United Kingdom perspective.

Influence of appendicular skeletal muscle mass on resting metabolic equivalents in patients with cardiovascular disease: Implications for exercise training and prescription (2019)
Journal Article
Nichols, S., O'Doherty, A., Carroll, S., & Ingle, L. (in press). Influence of appendicular skeletal muscle mass on resting metabolic equivalents in patients with cardiovascular disease: Implications for exercise training and prescription. European Journal of Preventive Cardiology, https://doi.org/10.1177/2047487319856432

Cardiorespiratory fitness as a predictor of short‐term and lifetime estimated cardiovascular disease risk (2019)
Journal Article
Swainson, M. G., Ingle, L., & Carroll, S. (2019). Cardiorespiratory fitness as a predictor of short‐term and lifetime estimated cardiovascular disease risk. Scandinavian Journal of Medicine and Science in Sports, 29(9), 1402-1413. https://doi.org/10.1111/sms.13468

Development of cardiovascular disease (CVD) remains a public health concern for young-to-middle-aged adults, now exacerbated by the increasing prevalence of obesity and sedentary lifestyles. Cardiorespiratory fitness (CRF) improves the reclassificati... Read More about Cardiorespiratory fitness as a predictor of short‐term and lifetime estimated cardiovascular disease risk.

Does exercise prescription based on estimated heart rate training zones exceed the ventilatory anaerobic threshold in patients with coronary heart disease undergoing usual-care cardiovascular rehabilitation? : a United Kingdom perspective (2019)
Journal Article
Pymer, S., Nichols, S., Prosser, J., Birkett, S., Carroll, S., & Ingle, L. (in press). Does exercise prescription based on estimated heart rate training zones exceed the ventilatory anaerobic threshold in patients with coronary heart disease undergoing usual-care cardiovascular rehabilitation? : a United Kingdom perspective. European Journal of Preventive Cardiology, https://doi.org/10.1177/2047487319852711

Background: In the United Kingdom (UK), exercise intensity is prescribed from a fixed percentage range (% heart rate reserve; %HRR) in cardiac rehabilitation (CR) programmes. We aimed to determine the accuracy of this approach by comparing it with an... Read More about Does exercise prescription based on estimated heart rate training zones exceed the ventilatory anaerobic threshold in patients with coronary heart disease undergoing usual-care cardiovascular rehabilitation? : a United Kingdom perspective.

The effects of low-volume high-intensity interval training and circuit training on maximal oxygen uptake (2019)
Journal Article
Birkett, S. T., Nichols, S., Sawrey, R., Gleadall-Siddall, D., McGregor, G., & Ingle, L. (2019). The effects of low-volume high-intensity interval training and circuit training on maximal oxygen uptake. Sport Sciences for Health, 15(2), 443–451. https://doi.org/10.1007/s11332-019-00552-2

Purpose High-intensity interval training (HIIT) and circuit training (CT) are popular methods of exercise, eliciting improvements in cardiorespiratory fitness (CRF). However, direct comparisons of these two training methods are limited. We investiga... Read More about The effects of low-volume high-intensity interval training and circuit training on maximal oxygen uptake.

Home-based exercise programmes for individuals with intermittent claudication: A protocol for an updated systematic review and meta-analysis (2018)
Journal Article
Pymer, S. A., Tew, G. A., Palmer, J., Ingle, L., Smith, G. E., Chetter, I. C., & Harwood, A. E. (2018). Home-based exercise programmes for individuals with intermittent claudication: A protocol for an updated systematic review and meta-analysis. SAGE Open Medicine, 6, https://doi.org/10.1177/2050312118818295

Background: The aim of this updated review is to consider the evidence base for the effectiveness of home-based exercise programmes as a treatment option for improving walking distance in patients with intermittent claudication. Methods: The Medline,... Read More about Home-based exercise programmes for individuals with intermittent claudication: A protocol for an updated systematic review and meta-analysis.

Low skeletal muscle mass is associated with low aerobic capacity and increased mortality risk in patients with coronary heart disease - a CARE CR study (2018)
Journal Article
Nichols, S., O'Doherty, A. F., Taylor, C., Clark, A. L., Carroll, S., & Ingle, L. (2019). Low skeletal muscle mass is associated with low aerobic capacity and increased mortality risk in patients with coronary heart disease - a CARE CR study. Clinical physiology and functional imaging, 39(1), 93-102. https://doi.org/10.1111/cpf.12539

BACKGROUND In patients with chronic heart failure, there is a positive linear relationship between skeletal muscle mass (SMM) and peak oxygen consumption (V˙O2peak ); an independent predictor of all-cause mortality. We investigated the association b... Read More about Low skeletal muscle mass is associated with low aerobic capacity and increased mortality risk in patients with coronary heart disease - a CARE CR study.

The BASES expert statement on exercise training for people with intermittent claudication due to peripheral arterial disease (2018)
Report
Tew, G., Harwood, A., Ingle, L., Chetter, I., & Doherty, P. (2018). The BASES expert statement on exercise training for people with intermittent claudication due to peripheral arterial disease. Leeds: British Association of Sports & Exercise Science

Lower-limb peripheral arterial disease (PAD) is a type of cardiovascular disease in which the blood vessels (arteries) that carry blood to the legs and feet are hardened and narrowed or blocked by the build-up of fatty plaques (called atheroma). It a... Read More about The BASES expert statement on exercise training for people with intermittent claudication due to peripheral arterial disease.

Is cardiorespiratory fitness related to cardiometabolic health and all-cause mortality risk in patients with coronary heart disease? A CARE CR study (2018)
Journal Article
Nichols, S., Taylor, C., Page, R., Kallvikbacka-Bennett, A., Nation, F., Goodman, T., …Ingle, L. (2018). Is cardiorespiratory fitness related to cardiometabolic health and all-cause mortality risk in patients with coronary heart disease? A CARE CR study. Sports Medicine - Open, 4(1), https://doi.org/10.1186/s40798-018-0138-z

© 2018, The Author(s). Background: Higher cardiorespiratory fitness (CRF) is associated with lower morbidity and mortality in patients with coronary heart disease (CHD). The mechanisms for this are not fully understood. A more favourable cardiometabo... Read More about Is cardiorespiratory fitness related to cardiometabolic health and all-cause mortality risk in patients with coronary heart disease? A CARE CR study.

Preferred exercise modalities in patients with intermittent claudication (2018)
Journal Article
Harwood, A., Hitchman, L. H., Ingle, L., Doherty, P., & Chetter, I. C. (2018). Preferred exercise modalities in patients with intermittent claudication. Journal of Vascular Nursing, 36(2), 81-84. https://doi.org/10.1016/j.jvn.2017.12.002

Conventional supervised exercise programs (SEPs) for claudicants are traditionally based on time-constrained, group-based structured programs usually at a hospital site. Uptake of an SEP is poor, despite the high-level evidence demonstrating its clin... Read More about Preferred exercise modalities in patients with intermittent claudication.

CARE CR-Cardiovascular and cardiorespiratory Adaptations to Routine Exercise-based Cardiac Rehabilitation: a study protocol for a community-based controlled study with criterion methods (2018)
Journal Article
Nichols, S., Nation, F., Goodman, T., Clark, A. L., Carroll, S., & Ingle, L. (2018). CARE CR-Cardiovascular and cardiorespiratory Adaptations to Routine Exercise-based Cardiac Rehabilitation: a study protocol for a community-based controlled study with criterion methods. BMJ open, 8(1), e019216. https://doi.org/10.1136/bmjopen-2017-019216

Introduction Cardiac rehabilitation (CR) reduces all-cause and cardiovascular mortality in patients with coronary heart disease (CHD). Much of this improvement has been attributed to the beneficial effects of structured exercise training. However, UK... Read More about CARE CR-Cardiovascular and cardiorespiratory Adaptations to Routine Exercise-based Cardiac Rehabilitation: a study protocol for a community-based controlled study with criterion methods.

The effects of acute interval exercise and strawberry intake on postprandial lipemia (2017)
Journal Article
O’Doherty, A., Jones, H. S., Sathyapalan, T., Ingle, L., & Carroll, S. (2017). The effects of acute interval exercise and strawberry intake on postprandial lipemia. Medicine and Science in Sports and Exercise, 49(11), 2315-2323. https://doi.org/10.1249/MSS.0000000000001341

Purpose: Raised postprandial triglycerides (TAG) and related oxidative stresses are strongly associated with increased cardiovascular disease (CVD) risk. Acute exercise and strawberry ingestion independently ameliorate postprandial lipid excursions a... Read More about The effects of acute interval exercise and strawberry intake on postprandial lipemia.

The effects of acute exercise and nutritional interventions on postprandial lipid metabolism (2017)
Thesis
O'Doherty, A. F. (2017). The effects of acute exercise and nutritional interventions on postprandial lipid metabolism. (Thesis). University of Hull. Retrieved from https://hull-repository.worktribe.com/output/4221286

Raised postprandial triglycerides (TG) is an independent risk factor for cardio-metabolic disorders. This is due, in part, to the increases in circulating remnant lipoproteins after TG have been transported for storage or hydrolysis. Raised TG, are a... Read More about The effects of acute exercise and nutritional interventions on postprandial lipid metabolism.

Estimated peak functional capacity: an accurate method for assessing change in peak oxygen consumption after cardiac rehabilitation? (2017)
Journal Article
Nichols, S., Gleadall-Siddall, D. O., Antony, R., Clark, A. L., Cleland, J. G. F., Carroll, S., & Ingle, L. (2018). Estimated peak functional capacity: an accurate method for assessing change in peak oxygen consumption after cardiac rehabilitation?. Clinical physiology and functional imaging, 38(4), 681-688. https://doi.org/10.1111/cpf.12468

Summary Objective Cardiopulmonary exercise testing (CPET) is the ‘gold standard’ method of determining VO2peak. When CPET is unavailable, VO2peak may be estimated from treadmill or cycle ergometer workloads and expressed as estimated metabolic equiva... Read More about Estimated peak functional capacity: an accurate method for assessing change in peak oxygen consumption after cardiac rehabilitation?.

A randomized controlled trial to establish the impact of aquatic exercise training on functional capacity, balance, and perceptions of fatigue in female patients with multiple sclerosis (2017)
Journal Article
Kargarfard, M., Shariat, A., Ingle, L., Cleland, J. A., & Kargarfard, M. (2018). A randomized controlled trial to establish the impact of aquatic exercise training on functional capacity, balance, and perceptions of fatigue in female patients with multiple sclerosis. Archives of physical medicine and rehabilitation, 99(2), 234-241. https://doi.org/10.1016/j.apmr.2017.06.015

Objective: To assess the effects of 8-weeks aquatic exercise training on functional capacity, balance, and perceptions of fatigue in women with multiple sclerosis (MS). Design: A randomized controlled design. Setting: Referral center of a multiple sc... Read More about A randomized controlled trial to establish the impact of aquatic exercise training on functional capacity, balance, and perceptions of fatigue in female patients with multiple sclerosis.

Exercise dose and all-cause mortality within extended cardiac rehabilitation: a cohort study (2017)
Journal Article
Taylor, C., Tsakirides, C., Moxon, J., Moxon, J. W., Dudfield, M., Witte, K., …Carroll, S. (2017). Exercise dose and all-cause mortality within extended cardiac rehabilitation: a cohort study. Open heart, 4(2), e000623. https://doi.org/10.1136/openhrt-2017-000623

Aims: To investigate the relationship between exercise participation, exercise ‘dose’ expressed as metabolic equivalent (MET) hours (h) per week, and prognosis in individuals attending an extended, community-based exercise rehabilitation programme. M... Read More about Exercise dose and all-cause mortality within extended cardiac rehabilitation: a cohort study.

Validity and reliability of the Apple Watch for measuring heart rate during exercise (2017)
Journal Article
Khushhal, A., Nichols, S., Evans, W., Gleadall-Siddall, D., Page, R., O'Doherty, A. F., …Abt, G. (2017). Validity and reliability of the Apple Watch for measuring heart rate during exercise. SMIO / Sports Medicine International Open, 1(6), E206-E211. https://doi.org/10.1055/s-0043-120195

We examined the validity and reliability of the Apple Watch heart rate sensor during and in recovery from exercise. Twenty-one males completed treadmill exercise while wearing two Apple Watches (left and right wrists) and a Polar S810i monitor (crite... Read More about Validity and reliability of the Apple Watch for measuring heart rate during exercise.

Validity of telemetric-derived measures of heart rate variability: a systematic review (2016)
Journal Article
Board, E. M., Ispoglou, T., & Ingle, L. (2016). Validity of telemetric-derived measures of heart rate variability: a systematic review. Journal of exercise physiology online / American Society of Exercise Physiologists, 19(6), 64-84

Heart rate variability (HRV) is a widely accepted indirect measure of autonomic function with widespread application across many settings. Although traditionally measured from the 'gold standard' criterion electrocardiography (ECG), the development o... Read More about Validity of telemetric-derived measures of heart rate variability: a systematic review.

Characterization of the metabolically healthy phenotype in overweight and obese British men (2016)
Journal Article
Ingle, L., Swainson, M., Brodie, D., & Sandercock, G. R. (2017). Characterization of the metabolically healthy phenotype in overweight and obese British men. Preventive Medicine, 94, 7-11. https://doi.org/10.1016/j.ypmed.2016.11.001

We calculated the prevalence of the metabolically healthy but obese (MHO) phenotype in (n=9 177) British men (age 48.9±7.4 years) attending preventive health screening between 2000 and 2009. We examined differences in cardiorespiratory fitness (Fitne... Read More about Characterization of the metabolically healthy phenotype in overweight and obese British men.

High-intensity interval training versus moderate-intensity steady-state training in UK cardiac rehabilitation programmes (HIIT or MISS UK): study protocol for a multicentre randomised controlled trial and economic evaluation (2016)
Journal Article
McGregor, G., Nichols, S., Hamborg, T., Bryning, L., Tudor-Edwards, R., Markland, D., …Backx, K. (2016). High-intensity interval training versus moderate-intensity steady-state training in UK cardiac rehabilitation programmes (HIIT or MISS UK): study protocol for a multicentre randomised controlled trial and economic evaluation. BMJ open, 6(11), e012843. https://doi.org/10.1136/bmjopen-2016-012843

Introduction: Current international guidelines for cardiac rehabilitation (CR) advocate moderate-intensity exercise training (MISS, moderate-intensity steady state). This recommendation predates significant advances in medical therapy for coronary he... Read More about High-intensity interval training versus moderate-intensity steady-state training in UK cardiac rehabilitation programmes (HIIT or MISS UK): study protocol for a multicentre randomised controlled trial and economic evaluation.

Associations between cardiorespiratory fitness and the metabolic syndrome in British men (2016)
Journal Article
Ingle, L., Mellis, M., Brodie, D., & Sandercock, G. R. (2017). Associations between cardiorespiratory fitness and the metabolic syndrome in British men. Heart, 103(7), 524-528. https://doi.org/10.1136/heartjnl-2016-310142

Background: Age and body mass index (BMI) are positively associated with the development of the metabolic syndrome (MetS). Cardiorespiratory fitness (CRF) can attenuate BMI-related increases in prevalence of MetS, but the nature of this association a... Read More about Associations between cardiorespiratory fitness and the metabolic syndrome in British men.

The repeatability of the abbreviated (4-h) Oral Fat Tolerance Test and influence of prior acute aerobic exercise (2016)
Journal Article
O’Doherty, A. F., Sathyapalan, T., Rigby, A. S., Ingle, L., & Carroll, S. (2018). The repeatability of the abbreviated (4-h) Oral Fat Tolerance Test and influence of prior acute aerobic exercise. European Journal of Nutrition, 57(1), 309-318. https://doi.org/10.1007/s00394-016-1320-z

© 2016 The Author(s) Purpose: The Oral Fat Tolerance Test (OFTT) is regarded as a repeatable measure used to assess postprandial triglyceride (TAG) levels, with higher levels observed in cardio-metabolic disorders. Acute aerobic exercise intervention... Read More about The repeatability of the abbreviated (4-h) Oral Fat Tolerance Test and influence of prior acute aerobic exercise.

Effects of exercise-based cardiac rehabilitation on cardiorespiratory fitness: A meta-analysis of UK studies (2016)
Journal Article
Ingle, L., Almodhy, M., & Sandercock, G. R. (2016). Effects of exercise-based cardiac rehabilitation on cardiorespiratory fitness: A meta-analysis of UK studies. International journal of cardiology, 221, 644-651. https://doi.org/10.1016/j.ijcard.2016.06.101

Background: Exercise-based cardiac rehabilitation can promote meaningful improvements in cardiorespiratory fitness (fitness) but the magnitude of such improvements varies according to local characteristics of exercise programmes. We aimed to determin... Read More about Effects of exercise-based cardiac rehabilitation on cardiorespiratory fitness: A meta-analysis of UK studies.

Submaximal fitness and mortality risk reduction in coronary heart disease: A retrospective cohort study of community-based exercise rehabilitation (2016)
Journal Article
Taylor, C., Tsakirides, C., Moxon, J., Moxon, J. W., Dudfield, M., Witte, K. K., …Carroll, S. (2016). Submaximal fitness and mortality risk reduction in coronary heart disease: A retrospective cohort study of community-based exercise rehabilitation. BMJ open, 6(6), Article e011125. https://doi.org/10.1136/bmjopen-2016-011125

Objectives To examine the association between submaximal cardiorespiratory fitness (sCRF) and all-cause mortality in a cardiac rehabilitation (CR) cohort. Design Retrospective cohort study of participants entering CR between 26 May 1993 and 16 Octob... Read More about Submaximal fitness and mortality risk reduction in coronary heart disease: A retrospective cohort study of community-based exercise rehabilitation.

Physical activity profiles and selected muscular fitness variables in English schoolchildren: A north–south divide? (2016)
Journal Article
Ingle, L., Stephenson, A., & Sandercock, G. R. (2016). Physical activity profiles and selected muscular fitness variables in English schoolchildren: A north–south divide?. European journal of sport science : the official journal of the European College of Sport Science, 16(8), 1187-1196. https://doi.org/10.1080/17461391.2016.1183714

Introduction: The aim of the study was to compare and contrast habitual physical activity profiles and muscular fitness in schoolchildren from northern and southern regions of England. Methods: Data were collected from two secondary schools in the No... Read More about Physical activity profiles and selected muscular fitness variables in English schoolchildren: A north–south divide?.

The cardiorespiratory and vascular adaptations to a routine UK exercise based cardiac rehabilitation programme (2015)
Thesis
Nichols, S. J. (2015). The cardiorespiratory and vascular adaptations to a routine UK exercise based cardiac rehabilitation programme. (Thesis). University of Hull. Retrieved from https://hull-repository.worktribe.com/output/4218451

Introduction: Recent data suggests that UK cardiac rehabilitation (CR) programmes do not substantially improve cardiorespiratory fitness (CRF) or patient survival. The exercise dose prescribed as part of a routine CR programme may be insufficient. Th... Read More about The cardiorespiratory and vascular adaptations to a routine UK exercise based cardiac rehabilitation programme.

The effect of structured exercise training on endothelial function in patients with coronary artery disease (2015)
Thesis
Du Preez, T. L. (2015). The effect of structured exercise training on endothelial function in patients with coronary artery disease. (Thesis). University of Hull. Retrieved from https://hull-repository.worktribe.com/output/4218497

Background: Endothelial function and arterial stiffness have shown to be predictive of cardiovascular risk. Aim: The study sought to investigate the effect of a current 8-week exercise based cardiac rehabilitation (CR) programme in the UK on endo... Read More about The effect of structured exercise training on endothelial function in patients with coronary artery disease.

A clinician's guide to cardiopulmonary exercise testing 2: test interpretation (2015)
Journal Article
Nichols, S., Taylor, C., & Ingle, L. (2015). A clinician's guide to cardiopulmonary exercise testing 2: test interpretation. British journal of hospital medicine, 76(5), 281-289. https://doi.org/10.12968/hmed.2015.76.5.281

Data obtained from cardiopulmonary exercise testing offer additional interpretive power over conventional exercise tolerance testing. When used correctly, these data allow improved clinical decision making in patients with cardiometabolic and respira... Read More about A clinician's guide to cardiopulmonary exercise testing 2: test interpretation.

A clinician's guide to cardiopulmonary exercise testing 1: An introduction (2015)
Journal Article
Nichols, S., Taylor, C., & Ingle, L. (2015). A clinician's guide to cardiopulmonary exercise testing 1: An introduction. British journal of hospital medicine, 76(4), 192-195. https://doi.org/10.12968/hmed.2015.76.4.192

Compared to standard exercise tolerance testing, cardiopulmonary exercise testing is a reliable and powerful tool that can be used for risk stratification, exercise prescription and clinical diagnosis.

Impact of exercise-induced bronchoconstriction on athletic performance and airway health in rugby union players (2014)
Journal Article
Dickinson, J., Ingle, L., Greenwell, J., & Spiteri, D. B. (2014). Impact of exercise-induced bronchoconstriction on athletic performance and airway health in rugby union players. International sportmed journal for FIMS ISMJ, 15(4), 333-342

All rights reserved. Background: There is emerging evidence that the prevalence of exercise-induced bronchospasm (EIB) is significantly under-reported in many sports. There is little known about the potential performance improvement that may exist wh... Read More about Impact of exercise-induced bronchoconstriction on athletic performance and airway health in rugby union players.

Cardiometabolic health benefits of a six-week high-intensity interval training intervention : a case study (2014)
Journal Article
Siddall-Gleadall, D., Gritt, J., Burke, R., O'Carroll, G., Bray, J., Ingle, L., & Garrett, A. (2014). Cardiometabolic health benefits of a six-week high-intensity interval training intervention : a case study. Journal of sports sciences, 32(Supplement 2), s28-s32. https://doi.org/10.1080/02640414.2014.968381

Regular physical activity is recommended for patients diagnosed with impaired glucose tolerance (IGT) and Type 2 Diabetes. However, "lack of time" is a common cited barrier in achieving the recommended weekly physical activity guidelines. High-intens... Read More about Cardiometabolic health benefits of a six-week high-intensity interval training intervention : a case study.

Cardiopulmonary exercise testing: an overview (2014)
Journal Article
McGregor, G., & Ingle, L. (2014). Cardiopulmonary exercise testing: an overview. British journal of cardiac nursing, 9(11), 541-543. https://doi.org/10.12968/bjca.2014.9.11.541

A cardiopulmonary exercise test (CPEX or CPET) is an exercise tolerance test which combines the standard measures of electrocardiography (ECG) and blood pressure with ventilatory gas exchange data. Despite having been available for many years, CPEX h... Read More about Cardiopulmonary exercise testing: an overview.

Effectiveness of a six-week high-intensity interval training programme on cardiometabolic markers in sedentary males (2014)
Conference Proceeding
Gleadall-Siddall, D., Burke, R., Gritt, J., O'Carroll, G., Bray, J., Ingle, L., & Garrett, A. (2014). Effectiveness of a six-week high-intensity interval training programme on cardiometabolic markers in sedentary males. . https://doi.org/10.1080/02640414.2014.968390

High-intensity interval training (HIT) has been proposed as an effective, time efficient strategy to elicit similar cardiometabolic health benefits as traditional moderate-intensity endurance training. This is an important consideration as "lack of t... Read More about Effectiveness of a six-week high-intensity interval training programme on cardiometabolic markers in sedentary males.

Variability of automated carotid intima-media thickness measurements by novice operators (2014)
Journal Article
Nichols, S., Milner, M., Meijer, R., Carroll, S., & Ingle, L. (2016). Variability of automated carotid intima-media thickness measurements by novice operators. Clinical physiology and functional imaging, 36(1), 25-32. https://doi.org/10.1111/cpf.12189

Carotid intima-media thickness (C-IMT) measurements provide a non-invasive assessment of sub-clinical atherosclerosis. The aim of the study was to assess the inter- and intra-observer variability of automated C-IMT measurements undertaken by two novi... Read More about Variability of automated carotid intima-media thickness measurements by novice operators.

The relation between repeated 6-minute walk test performance and outcome in patients with chronic heart failure (2014)
Journal Article
Ingle, L., Cleland, J. G., & Clark, A. L. (2014). The relation between repeated 6-minute walk test performance and outcome in patients with chronic heart failure. Annals of physical and rehabilitation medicine, 57(4), 244-253. https://doi.org/10.1016/j.rehab.2014.03.004

Objective: To assess the prognostic implications of the 6-minute walk test (6-MWT) distance measured twice, one year apart, in a large sample of patients with chronic heart failure (CHF) followed for an extended period ( > . 8. years from baseline).... Read More about The relation between repeated 6-minute walk test performance and outcome in patients with chronic heart failure.

The long-term prognostic significance of 6-minute walk test distance in patients with chronic heart failure (2014)
Journal Article
Ingle, L., Cleland, J. G., & Clark, A. L. (2014). The long-term prognostic significance of 6-minute walk test distance in patients with chronic heart failure. Biomed research international, 2014, 1-7. https://doi.org/10.1155/2014/505969

Background. The 6-minute walk test (6-MWT) is used to assess patients with chronic heart failure (CHF). The prognostic significance of the 6-MWT distance during long-term followup ( > 5 years) is unclear. Methods. 1,667 patients (median [inter-quarti... Read More about The long-term prognostic significance of 6-minute walk test distance in patients with chronic heart failure.

Development of a composite model derived from cardiopulmonary exercise tests to predict mortality risk in patients with mild-to-moderate heart failure (2014)
Journal Article
Ingle, L., Rigby, A. S., Sloan, R., Carroll, S., Goode, K. M., Cleland, J. G., & Clark, A. L. (2014). Development of a composite model derived from cardiopulmonary exercise tests to predict mortality risk in patients with mild-to-moderate heart failure. Heart, 100(10), 781-786. https://doi.org/10.1136/heartjnl-2013-304614

Objective: Cardiopulmonary exercise testing (CPET) is used to predict outcome in patients with mild-to-moderate heart failure (HF). Single CPET-derived variables are often used, but we wanted to see if a composite score achieved better predictive pow... Read More about Development of a composite model derived from cardiopulmonary exercise tests to predict mortality risk in patients with mild-to-moderate heart failure.

Variability in heart rate recovery measurements over 1 year in healthy, middle-aged adults (2014)
Journal Article
Mellis, M. G., Ingle, L., & Carroll, S. (2014). Variability in heart rate recovery measurements over 1 year in healthy, middle-aged adults. International journal of sports medicine, 35(2), 135-138. https://doi.org/10.1055/s-0033-1349091

This study assessed the longer-term (12-month) variability in post-exercise heart rate recovery following a submaximal exercise test. Longitudinal data was analysed for 97 healthy middle-aged adults (74 male, 23 female) from 2 occasions, 12 months ap... Read More about Variability in heart rate recovery measurements over 1 year in healthy, middle-aged adults.

The variability of high intensity exercise tests in pre-pubertal boys (2013)
Journal Article
Ingle, L., & Tolfrey, K. (2013). The variability of high intensity exercise tests in pre-pubertal boys. International journal of sports medicine, 34(12), 1063-1069. https://doi.org/10.1055/s-0032-1327714

The aim of the study was to determine the variability of different performance tests during high intensity exercise in active, untrained pre- and early pubertal boys. Participants were habituated to the Wingate anaerobic test (WAnT), force-velocity t... Read More about The variability of high intensity exercise tests in pre-pubertal boys.

Effects of reducing inspired oxygen concentration for one hour in patients with chronic heart failure: implications for air travel (2013)
Journal Article
Hobkirk, J. P., Damy, T., Walters, M., Bennett, A., Smith, S. J., Ingle, L., …Cleland, J. G. (2013). Effects of reducing inspired oxygen concentration for one hour in patients with chronic heart failure: implications for air travel. European journal of heart failure, 15(5), 505-510. https://doi.org/10.1093/eurjhf/hft003

AimsThe objective of this study was to establish the acute effects of hypoxia on clinical, spirometric, haemodynamic, and echocardiographic variables. Reducing inspired oxygen to 15%, as experienced during commercial air travel, decreases arterial ox... Read More about Effects of reducing inspired oxygen concentration for one hour in patients with chronic heart failure: implications for air travel.

Abnormalities of the ventilatory equivalent for carbon dioxide in patients with chronic heart failure (2012)
Journal Article
Ingle, L., Sloan, R., Carroll, S., Goode, K., Cleland, J. G., & Clark, A. L. (2012). Abnormalities of the ventilatory equivalent for carbon dioxide in patients with chronic heart failure. Pulmonary Medicine, 2012, 589164. https://doi.org/10.1155/2012/589164

Introduction. The relation between minute ventilation (VE) and carbon dioxide production (VCO(2)) can be characterised by the instantaneous ratio of ventilation to carbon dioxide production, the ventilatory equivalent for CO(2) (VEqCO(2)). We hypothe... Read More about Abnormalities of the ventilatory equivalent for carbon dioxide in patients with chronic heart failure.

Cardiorespiratory fitness and heart rate recovery in obese premenopausal women (2012)
Journal Article
Carroll, S., Marshall, P., Ingle, L., & Borkoles, E. (2012). Cardiorespiratory fitness and heart rate recovery in obese premenopausal women. Scandinavian Journal of Medicine and Science in Sports, 22(6), e133-e139. https://doi.org/10.1111/j.1600-0838.2012.01522.x

Post-exercise heart rate recovery (HRR) has been proposed as a measure of cardiac autonomic dysfunction in apparently healthy adults. We aimed to determine the effects of a lifestyle intervention on HRR among clinically obese premenopausal women. A r... Read More about Cardiorespiratory fitness and heart rate recovery in obese premenopausal women.

Physical activity and cardiovascular mortality risk: possible protective mechanisms? (2012)
Journal Article
Hamer, M., Ingle, L., Carroll, S., & Stamatakis, E. (2012). Physical activity and cardiovascular mortality risk: possible protective mechanisms?. Medicine and Science in Sports and Exercise, 44(1), 84-88. https://doi.org/10.1249/mss.0b013e3182251077

INTRODUCTION: The biological mechanisms through which increased physical activity or structured exercise training lowers the risk of recurrent cardiac events are incompletely understood. We examined the extent to which modification of primary risk ma... Read More about Physical activity and cardiovascular mortality risk: possible protective mechanisms?.

Influence of step length on 6-minute walk test performance in patients with chronic heart failure (2011)
Journal Article
Pepera, G. K., Sandercock, G. R., Sloan, R., Cleland, J. J., Ingle, L., & Clark, A. L. (2012). Influence of step length on 6-minute walk test performance in patients with chronic heart failure. Physiotherapy, 98(4), 325-329. https://doi.org/10.1016/j.physio.2011.08.005

Objective: To investigate the influence of gait parameters including step length and walking speed during performance of the 6-minute walking test (6MWT) in patients with chronic heart failure (CHF). Design: Observational study. Setting: Specialist h... Read More about Influence of step length on 6-minute walk test performance in patients with chronic heart failure.

Differential Improvements in Lipid Profiles and Framingham Recurrent Risk Score in Patients With and Without Diabetes Mellitus Undergoing Long-Term Cardiac Rehabilitation (2011)
Journal Article
Carroll, S., Tsakirides, C., Hobkirk, J., Moxon, J. W. D., Dudfield, M., & Ingle, L. (2011). Differential Improvements in Lipid Profiles and Framingham Recurrent Risk Score in Patients With and Without Diabetes Mellitus Undergoing Long-Term Cardiac Rehabilitation. Archives of physical medicine and rehabilitation, 92(9), 1382-1387. https://doi.org/10.1016/j.apmr.2011.04.013

OBJECTIVE: To determine whether lipid profiles and recurrent coronary heart disease (CHD) risk could be modified in patients with and without diabetes mellitus undergoing long-term cardiac rehabilitation (CR). DESIGN: Retrospective analysis of patien... Read More about Differential Improvements in Lipid Profiles and Framingham Recurrent Risk Score in Patients With and Without Diabetes Mellitus Undergoing Long-Term Cardiac Rehabilitation.

Benefit of adding lifestyle-related risk factors for prediction of cardiovascular death among cardiac patients. (2011)
Journal Article
Carroll, S., Ingle, L., Hamer, M., & Stamatakis, E. (2013). Benefit of adding lifestyle-related risk factors for prediction of cardiovascular death among cardiac patients. International journal of cardiology, 163(2), 196-200. https://doi.org/10.1016/j.ijcard.2011.06.001

OBJECTIVE: The aim of our study was to evaluate the efficacy of the addition of lifestyle related variables to the existing Framingham risk score (FRS) for predicting cardiovascular death in patients with pre-existing cardiovascular disease (CVD). DE... Read More about Benefit of adding lifestyle-related risk factors for prediction of cardiovascular death among cardiac patients..

Benefit of adding lifestyle-related risk factors for prediction of cardiovascular death among cardiac patients (2011)
Journal Article
Ingle, L., Carroll, S., Stamatakis, E., & Hamer, M. (2013). Benefit of adding lifestyle-related risk factors for prediction of cardiovascular death among cardiac patients. International journal of cardiology, 163(2), 196-200. https://doi.org/10.1016/j.ijcard.2011.06.001

Objective: The aim of our study was to evaluate the efficacy of the addition of lifestyle related variables to the existing Framingham risk score (FRS) for predicting cardiovascular death in patients with pre-existing cardiovascular disease (CVD). De... Read More about Benefit of adding lifestyle-related risk factors for prediction of cardiovascular death among cardiac patients.

Effects of high and low concentration carbohydrate solution on endurance performance consumed prior to and during intense, intermittent exercise (2011)
Journal Article
Ingle, L., Cooke, C., & King, R. (2011). Effects of high and low concentration carbohydrate solution on endurance performance consumed prior to and during intense, intermittent exercise. Medicina Sportiva, 15(2), 62-67

The aim of the study was to compare the effects of high and low concentration carbohydrate (CHO) solutions on the endurance performance of recreational, male soccer players consumed prior to and during intense, intermittent exercise. Methods: Seven p... Read More about Effects of high and low concentration carbohydrate solution on endurance performance consumed prior to and during intense, intermittent exercise.

Prognostic significance of different measures of the ventilation-carbon dioxide relation in patients with suspected heart failure (2011)
Journal Article
Ingle, L., Sloan, R., Carroll, S., Goode, K., Cleland, J. G., & Clark, A. L. (2011). Prognostic significance of different measures of the ventilation-carbon dioxide relation in patients with suspected heart failure. European journal of heart failure, 13(5), 537-542. https://doi.org/10.1093/eurjhf/hfq238

Aims We studied the prognostic significance of the ventilatory equivalent of carbon dioxide production (VEqCO 2 ) at different time-points of a maximal cardiopulmonary exercise test (CPET) in patients with suspected heart failure (HF). Methods and re... Read More about Prognostic significance of different measures of the ventilation-carbon dioxide relation in patients with suspected heart failure.

Experiences of air travel in patients with chronic heart failure (2011)
Journal Article
Ingle, L., Hobkirk, J., Damy, T., Nabb, S., Clark, A. L., & Cleland, J. G. (2012). Experiences of air travel in patients with chronic heart failure. International journal of cardiology, 158(1), 66-70. https://doi.org/10.1016/j.ijcard.2010.12.101

AIM: To conduct a survey in a representative cohort of ambulatory patients with stable, well managed chronic heart failure (CHF) to discover their experiences of air travel. METHODS: An expert panel including a cardiologist, an exercise scientist, an... Read More about Experiences of air travel in patients with chronic heart failure.

Impact of a short-term, moderate intensity, lower volume circuit resistance training programme on metabolic risk factors in overweight/obese type 2 diabetics (2010)
Journal Article
Hazley, L., Ingle, L., Tsakirides, C., Carroll, S., & Nagi, D. (2010). Impact of a short-term, moderate intensity, lower volume circuit resistance training programme on metabolic risk factors in overweight/obese type 2 diabetics. Research in Sports Medicine, 18(4), 251-262. https://doi.org/10.1080/15438627.2010.510049

The purpose of this study was to evaluate the effects of an 8-week, low frequency, hospital-based resistance training programme on metabolic risk factors in type 2 diabetic patients. Participants were self-selected into either an 8-week resistance tr... Read More about Impact of a short-term, moderate intensity, lower volume circuit resistance training programme on metabolic risk factors in overweight/obese type 2 diabetics.

Cardiac output does not limit submaximal exercise capacity in patients with chronic heart failure (2010)
Journal Article
Shelton, R. J., Ingle, L., Rigby, A. S., Witte, K. K., Cleland, J. G., & Clark, A. L. (2010). Cardiac output does not limit submaximal exercise capacity in patients with chronic heart failure. European journal of heart failure, 12(9), 983-989. https://doi.org/10.1093/eurjhf/hfq086

Aims Mechanisms of exercise limitation in patients with chronic heart failure (CHF) are incompletely understood. During matched submaximal, fixed-rate exercise, oxygen uptake is similar in patients and healthy controls. However, the importance of ca... Read More about Cardiac output does not limit submaximal exercise capacity in patients with chronic heart failure.

Pre-participation cardiac screening in young athletes: models and criteria (2010)
Journal Article
Ingle, L. (2010). Pre-participation cardiac screening in young athletes: models and criteria. British journal of cardiac nursing, 5(9), 426-431. https://doi.org/10.12968/bjca.2010.5.9.78127

This is the second of two review articles focusing on the value of preparticipation cardiac screening in young athletes. The article focuses on the efficacy of the resting 12-lead electrocardiogram (ECG), physical examination, and medical history que... Read More about Pre-participation cardiac screening in young athletes: models and criteria.

Pre-participation cardiac screening: considerations for young athletes (2010)
Journal Article
Ingle, L. (2010). Pre-participation cardiac screening: considerations for young athletes. British journal of cardiac nursing, 5(8), 381-384. https://doi.org/10.12968/bjca.2010.5.8.66249

This article is the first of two focusing on the utility and evidence base for pre-participation cardiac screening in competitive athletic populations. The second article will focus on the diagnostic value of different screening modalities used in th... Read More about Pre-participation cardiac screening: considerations for young athletes.

Screening for cardiovascular risk in patients with anorexia nervosa (2010)
Journal Article
Ingle, L. (2010). Screening for cardiovascular risk in patients with anorexia nervosa. British journal of cardiac nursing, 5(7), 332-337. https://doi.org/10.12968/bjca.2010.5.7.48926

In young people, especially females, a high importance is placed on body image and physical appearance. Unfortunately, misperceptions of the ideal body shape can encourage a pre-occupation with weight loss strategies. Long-term, these strategies may... Read More about Screening for cardiovascular risk in patients with anorexia nervosa.

Detraining effect of the post-season on selected aerobic and anaerobic performance variables in national league rugby union players: a focus on positional status (2010)
Journal Article
Nirmalendran, R., & Ingle, L. (2010). Detraining effect of the post-season on selected aerobic and anaerobic performance variables in national league rugby union players: a focus on positional status. Medicina Sportiva, 14(4), 161-168

Introduction: The study aimed to assess the effects of 6 weeks post-season detraining in relation to player position on selected anaerobic, aerobic and anthropometric characteristics in sub-elite rugby union players. Methods: 34 English National Div... Read More about Detraining effect of the post-season on selected aerobic and anaerobic performance variables in national league rugby union players: a focus on positional status.

Derivation and validation of a simple clinical risk-model in heart failure based on 6 minute walk test performance and NT-proBNP status - Do we need specificity for sex and beta-blockers? (2009)
Journal Article
Frankenstein, L., Goode, K., Ingle, L., Remppis, A., Schellberg, D., Nelles, M., …Zugck, C. (2011). Derivation and validation of a simple clinical risk-model in heart failure based on 6 minute walk test performance and NT-proBNP status - Do we need specificity for sex and beta-blockers?. International journal of cardiology, 147(1), 74-78. https://doi.org/10.1016/j.ijcard.2009.08.005

BACKGROUND It is unclear whether risk prediction strategies in chronic heart failure (CHF) need to be specific for sex or beta-blockers. We examined this problem and developed and validated the consequent risk models based on 6-minute-walk-test and N... Read More about Derivation and validation of a simple clinical risk-model in heart failure based on 6 minute walk test performance and NT-proBNP status - Do we need specificity for sex and beta-blockers?.

A review of the six-minute walk test: Its implication as a self-administered assessment tool (2009)
Journal Article
Ingle, L. (2009). A review of the six-minute walk test: Its implication as a self-administered assessment tool. European journal of cardiovascular nursing : journal of the Working Group on Cardiovascular Nursing of the European Society of Cardiology, 8(3), 232-234. https://doi.org/10.1016/j.ejcnurse.2009.01.002

I read with interest the review article by Du and colleagues published in the European Journal of Cardiovascular Nursing in July 2008. The concept that the six-minute walk test (6-MWT) could be adapted as a patient-reported outcome measure of functio... Read More about A review of the six-minute walk test: Its implication as a self-administered assessment tool.

Impact of different diagnostic criteria on the prevalence and prognostic significance of exertional oscillatory ventilation in patients with chronic heart failure (2009)
Journal Article
Ingle, L., Isted, A., Witte, K. K., Cleland, J. G., & Clark, A. L. (2009). Impact of different diagnostic criteria on the prevalence and prognostic significance of exertional oscillatory ventilation in patients with chronic heart failure. European journal of cardiovascular prevention and rehabilitation, 16(4), 451-456. https://doi.org/10.1097/HJR.0b013e32832a4f54

INTRODUCTION: Exertional oscillatory ventilation (EOV) occurs in many patients with chronic heart failure. Two different definitions of EOV have been proposed by Corrá and Leite. We aimed to compare the prevalence of EOV and its prognostic significan... Read More about Impact of different diagnostic criteria on the prevalence and prognostic significance of exertional oscillatory ventilation in patients with chronic heart failure.

An evaluation of a primary and secondary care cardiac rehabilitation service pathway (2009)
Journal Article
Trotman-Beasty, A., McKenna, J., & Ingle, L. (2009). An evaluation of a primary and secondary care cardiac rehabilitation service pathway. British journal of cardiac nursing, 4(4), 178-184

Background: The aim of the study was to assess the synergy between patient treatment pathways in two large primary care trusts (PCTs) and general practices for patients following myocardial infarction (MI) and after completing a 12-week cardiac rehab... Read More about An evaluation of a primary and secondary care cardiac rehabilitation service pathway.

Prognostic Significance of the Double Pressure Reserve in Patients with Chronic Heart Failure (2009)
Journal Article
Ingle, L., & Clark, A. (2009). Prognostic Significance of the Double Pressure Reserve in Patients with Chronic Heart Failure. Open Heart Failure Journal, 2, 1-5. https://doi.org/10.2174/1876535100902010001

Abstract: Introduction: The double pressure reserve (DPR) has recently been shown to have greater prognostic power than metabolic equivalents, heart rate indices, and systolic blood pressure in healthy subjects. It is unclear whether DPR offers any... Read More about Prognostic Significance of the Double Pressure Reserve in Patients with Chronic Heart Failure.

Physical activity readiness in patient withdrawals from cardiac rehabilitation. (2009)
Journal Article
Rivett, M. J., Tsakirides, C., Pringle, A., Carroll, S., Ingle, L., & Dudfield, M. (2009). Physical activity readiness in patient withdrawals from cardiac rehabilitation. British Journal of Nursing, 18(3), 188-191. https://doi.org/10.12968/bjon.2009.18.3.39050

BACKGROUND: Adherence to cardiac rehabilitation (CR) programmes may be an important element for improving and maintaining physical activity (PA) behaviour in secondary prevention. Little is known about the PA behaviour in patients who have withdrawn... Read More about Physical activity readiness in patient withdrawals from cardiac rehabilitation..

Hospital versus community-based phase III cardiac rehabilitation. (2009)
Journal Article
Blake, E., Tsakirides, C., & Ingle, L. (2009). Hospital versus community-based phase III cardiac rehabilitation. British Journal of Nursing, 18(2), 116-122. https://doi.org/10.12968/bjon.2009.18.2.37867

AIM: to compare patient and staff perceptions of phase III cardiac rehabilitation delivered in a hospital versus community setting. METHOD: data were collected by semi-structured interviews with staff and patients. Patients and staff members were int... Read More about Hospital versus community-based phase III cardiac rehabilitation..

The prognostic value of individual NT-proBNP values in chronic heart failure does not change with advancing age (2009)
Journal Article
Frankenstein, L., Clark, A. L., Goode, K., Ingle, L., Remppis, A., Schellberg, D., …Zugck, C. (2009). The prognostic value of individual NT-proBNP values in chronic heart failure does not change with advancing age. Heart, 95(10), 825-829. https://doi.org/10.1136/hrt.2008.158626

Background: It is unclear whether age-related increases in N-terminal pro-brain natriuretic peptide (NT-proBNP) represent a normal physiological process - possibly affecting the prognostic power - of NT-proBNP - or reflect age-related subclinical pat... Read More about The prognostic value of individual NT-proBNP values in chronic heart failure does not change with advancing age.

Perception of symptoms is out of proportion to cardiac pathology in patients with "diastolic heart failure" (2008)
Journal Article
Ingle, L., Cleland, J. G., & Clark, A. L. (2008). Perception of symptoms is out of proportion to cardiac pathology in patients with "diastolic heart failure". Heart, 94(6), 748-753. https://doi.org/10.1136/hrt.2007.131144

Background: Epidemiological studies suggest that "diastolic heart failure" (DHF) is common and has a prognosis similar to that of systolic heart failure (SHF). We wanted to assess whether patients with breathlessness who were being treated for DHF ha... Read More about Perception of symptoms is out of proportion to cardiac pathology in patients with "diastolic heart failure".

Prognostic value and diagnostic potential of cardiopulmonary exercise testing in patients with chronic heart failure (2008)
Journal Article
Ingle, L. (2008). Prognostic value and diagnostic potential of cardiopulmonary exercise testing in patients with chronic heart failure. European journal of heart failure, 10(2), 112-118. https://doi.org/10.1016/j.ejheart.2007.12.011

Cardiopulmonary exercise testing (CPET) is a well established technique for stratifying cardiovascular risk in patients with chronic heart failure (CHF). Important prognostic variables include a reduced peak oxygen uptake which has a central use in c... Read More about Prognostic value and diagnostic potential of cardiopulmonary exercise testing in patients with chronic heart failure.

Combining the ventilatory response to exercise and peak oxygen consumption is no better than peak oxygen consumption alone in predicting mortality in chronic heart failure (2008)
Journal Article
Ingle, L., Witte, K. K., Cleland, J. G. F., & Clark, A. L. (2008). Combining the ventilatory response to exercise and peak oxygen consumption is no better than peak oxygen consumption alone in predicting mortality in chronic heart failure. European journal of heart failure, 10(1), 85-88. https://doi.org/10.1016/j.ejheart.2007.10.010

Background: A low peak oxygen uptake (pV(O2)) and steep V-E/V-CO2 slope are independently associated with a worse prognosis in patients with chronic heart failure (CHF). We wished to confirm whether combining these variables as a ratio would lead to... Read More about Combining the ventilatory response to exercise and peak oxygen consumption is no better than peak oxygen consumption alone in predicting mortality in chronic heart failure.

Perception of symptoms is out of proportion to cardiac pathology in patients with "diastolic heart failure'' (2007)
Journal Article
Ingle, L., Cleland, J. G. F., & Clark, A. L. (2008). Perception of symptoms is out of proportion to cardiac pathology in patients with "diastolic heart failure''. Heart, 94(6), 748-753. https://doi.org/10.1136/hrt.2007.131144

Background: Epidemiological studies suggest that "diastolic heart failure'' (DHF) is common and has a prognosis similar to that of systolic heart failure (SHF). We wanted to assess whether patients with breathlessness who were being treated for DHF h... Read More about Perception of symptoms is out of proportion to cardiac pathology in patients with "diastolic heart failure''.

Value of the 6-minute walk test in older patients with chronic heart failure (2007)
Journal Article
Ingle, L. (2007). Value of the 6-minute walk test in older patients with chronic heart failure. Cardiology in review, 24(10), 29-32

We assessed the prognostic value of the 6-minute walk test (6-MWT) among 1592 subjects with differing degrees of left ventricular systolic dysfunction (LVSD). We found that the 6-MWT was an independent predictor of mortality, particularly among patie... Read More about Value of the 6-minute walk test in older patients with chronic heart failure.

The prognostic value of cardiopulmonary exercise testing with a peak respiratory exchange ratio of < 1.0 in patients with chronic heart failure (2007)
Journal Article
Ingle, L., Witte, K. K., Cleland, J. G., & Clark, A. L. (2008). The prognostic value of cardiopulmonary exercise testing with a peak respiratory exchange ratio of < 1.0 in patients with chronic heart failure. International journal of cardiology, 127(1), 88-92. https://doi.org/10.1016/j.ijcard.2007.04.075

Background: Peak oxygen consumption derived from a maximal cardiopulmonary exercise test (CPET) is a standard prognostic indicator in patients with chronic heart failure (CHF). Tests with a peak respiratory exchange ratio (pRER) < 1.0 are often tak... Read More about The prognostic value of cardiopulmonary exercise testing with a peak respiratory exchange ratio of < 1.0 in patients with chronic heart failure.

Changes in body composition in patients with left ventricular systolic dysfunction initiated on beta-blocker therapy (2007)
Journal Article
Ingle, L., Rigby, A. S., Carroll, S., Butterly, R., King, R. F., Cooke, C. B., …Clark, A. L. (2007). Changes in body composition in patients with left ventricular systolic dysfunction initiated on beta-blocker therapy. Experimental and Clinical Cardiology, 12(1), 46-47

Background: Increasing body mass index, cholesterol and body fat are associated with a better prognosis in patients with left ventricular systolic dysfunction (LVSD). Beta-blocker usage is associated with changes in body composition and increased bod... Read More about Changes in body composition in patients with left ventricular systolic dysfunction initiated on beta-blocker therapy.

Cardiorespiratory requirements of the 6-min walk test in older patients with left ventricular systolic dysfunction and no major structural heart disease (2007)
Journal Article
Ingle, L., Wilkinson, M., Carroll, S., Boyes, C., Butterly, R., King, R., …Clark, A. (2007). Cardiorespiratory requirements of the 6-min walk test in older patients with left ventricular systolic dysfunction and no major structural heart disease. International journal of sports medicine, 28(8), 678-684. https://doi.org/10.1055/s-2007-964886

The six-minute walk test (6-MWT) is widely used to assess functional status in patients with chronic heart failure (CHF). The aims of the present study were: (1) to compare metabolic gas exchange during the 6-MWT in older patients with left ventricul... Read More about Cardiorespiratory requirements of the 6-min walk test in older patients with left ventricular systolic dysfunction and no major structural heart disease.

Theoretical rationale and practical recommendations for cardiopulmonary exercise testing in patients with chronic heart failure (2007)
Journal Article
Ingle, L. (2007). Theoretical rationale and practical recommendations for cardiopulmonary exercise testing in patients with chronic heart failure. Heart Failure Reviews, 12(1), 12-22. https://doi.org/10.1007/s10741-007-9000-y

The syndrome of chronic heart failure (CHF) becomes increasingly prevalent in older patients, and while mortality rates are declining in most cardiovascular diseases, both prevalence and mortality in CHF remain high. The heart is unable to meet the d... Read More about Theoretical rationale and practical recommendations for cardiopulmonary exercise testing in patients with chronic heart failure.

Prognostic value of the 6 min walk test and self-perceived symptom severity in older patients with chronic heart failure (2007)
Journal Article
Ingle, L., Rigby, A. S., Carroll, S., Butterly, R., King, R. F., Cooke, C. B., …Clark, A. L. (2007). Prognostic value of the 6 min walk test and self-perceived symptom severity in older patients with chronic heart failure. European Heart Journal, 28(5), 560-568. https://doi.org/10.1093/eurheartj/ehl527

Background: The 6 min walk test (6-MWT) is a simple and popular test for evaluating functional status in patients with chronic heart failure (CHF). However, the prognostic value of the 6-MWT in a large, representative sample of CHF patients, and in p... Read More about Prognostic value of the 6 min walk test and self-perceived symptom severity in older patients with chronic heart failure.

Efficacy of lifestyle intervention on peak exercise cardiac power output and reserve in premenopausal obese females: A randomised pilot study (2007)
Journal Article
Carroll, S., Marshall, P., Borkoles, E., Ingle, L., Barker, D., & Tan, L. B. (2007). Efficacy of lifestyle intervention on peak exercise cardiac power output and reserve in premenopausal obese females: A randomised pilot study. International journal of cardiology, 119(2), 147-155. https://doi.org/10.1016/j.ijcard.2006.07.099

Background: Clinically obese women have a two-fold increased risk for the development of heart failure. Among younger premenopausal females, obesity has been associated with cardiac remodelling and impaired resting systolic and diastolic function. Ho... Read More about Efficacy of lifestyle intervention on peak exercise cardiac power output and reserve in premenopausal obese females: A randomised pilot study.

Prognostic value of the VE/VCO2 slope calculated from different time intervals in patients with suspected heart failure (2006)
Journal Article
Ingle, L., Goode, K., Carroll, S., Sloan, R., Boyes, C., Cleland, J. G., & Clark, A. L. (2007). Prognostic value of the VE/VCO2 slope calculated from different time intervals in patients with suspected heart failure. International journal of cardiology, 118(3), 350-355. https://doi.org/10.1016/j.ijcard.2006.07.105

Background: Maximal exercises testing, whether involving cycling- or walking-based protocols, are often not well tolerated in patients with chronic heart failure (CHF). The peak oxygen consumption and the slope of the relation between ventilation (V... Read More about Prognostic value of the VE/VCO2 slope calculated from different time intervals in patients with suspected heart failure.

The effect of a complex training and detraining programme on selected strength and power variables in early pubertal boys (2006)
Journal Article
Ingle, L., Sleap, M., & Tolfrey, K. (2006). The effect of a complex training and detraining programme on selected strength and power variables in early pubertal boys. Journal of sports sciences, 24(9), 987-997. https://doi.org/10.1080/02640410500457117

Complex training, a combination of resistance training and plyometrics is growing in popularity, despite limited support for its efficacy. In pre- and early pubertal children, the study of complex training has been limited, and to our knowledge an ex... Read More about The effect of a complex training and detraining programme on selected strength and power variables in early pubertal boys.

Participants' perceptions of a lifestyle approach to promoting physical activity: targeting deprived communities in Kingston-Upon-Hull (2006)
Journal Article
Wormald, H., Waters, H., Sleap, M., & Ingle, L. (2006). Participants' perceptions of a lifestyle approach to promoting physical activity: targeting deprived communities in Kingston-Upon-Hull. BMC public health, 6, Article 202. https://doi.org/10.1186/1471-2458-6-202

Background: The health benefits of an active lifestyle have been extensively documented and generally accepted. In the UK, declining physical activity levels are a major contributing factor to a number of public health concerns such as obesity and co... Read More about Participants' perceptions of a lifestyle approach to promoting physical activity: targeting deprived communities in Kingston-Upon-Hull.

Clinical determinants of poor six-minute walk test performance in patients with left ventricular systolic dysfunction and no major structural heart disease (2006)
Journal Article
Ingle, L., Rigby, A. S., Nabb, S., Jones, P. K., Clark, A. L., & Cleland, J. G. (2006). Clinical determinants of poor six-minute walk test performance in patients with left ventricular systolic dysfunction and no major structural heart disease. European journal of heart failure, 8(3), 321-325. https://doi.org/10.1016/j.ejheart.2005.08.006

Background: The clinical determinants of six-minute walk test (6-MWT) performance in patients with left ventricular systolic dysfunction (LVSD) have rarely been investigated, and it is not clear whether they differ from patients referred for the asse... Read More about Clinical determinants of poor six-minute walk test performance in patients with left ventricular systolic dysfunction and no major structural heart disease.

Poor relationship between exercise capacity and spirometric measurements in patients with more symptomatic heart failure (2005)
Journal Article
Ingle, L., Shelton, R. J., Cleland, J. G., & Clark, A. L. (2005). Poor relationship between exercise capacity and spirometric measurements in patients with more symptomatic heart failure. Journal of cardiac failure, 11(8), 619-623. https://doi.org/10.1016/j.cardfail.2005.06.430

Background: The origin of exercise limitation in patients with chronic heart failure (CHF) is multifactorial, and the relative contributions of different abnormalities may vary with severity of heart failure symptoms. The aim of the current study was... Read More about Poor relationship between exercise capacity and spirometric measurements in patients with more symptomatic heart failure.

Clinical trials update from the European Society of Cardiology Heart Failure meeting and the American College of Cardiology: Darbepoetin alfa study, ECHOS, and ASCOT-BPLA (2005)
Journal Article
Cleland, J. G., Coletta, A. P., Clark, A. L., Velavan, P., & Ingle, L. (2005). Clinical trials update from the European Society of Cardiology Heart Failure meeting and the American College of Cardiology: Darbepoetin alfa study, ECHOS, and ASCOT-BPLA. European journal of heart failure, 7(5), 937-939. https://doi.org/10.1016/j.ejheart.2005.07.001

This article provides information and a commentary on landmark trials presented at the European Society of Cardiology Heart Failure meeting held in June 2005, relevant to the pathophysiology, prevention and treatment of heart failure. All reports sho... Read More about Clinical trials update from the European Society of Cardiology Heart Failure meeting and the American College of Cardiology: Darbepoetin alfa study, ECHOS, and ASCOT-BPLA.

The reproducibility and sensitivity of the 6-min walk test in elderly patients with chronic heart failure (2005)
Journal Article
Ingle, L., Shelton, R. J., Rigby, A. S., Nabb, S., Clark, A. L., & Cleland, J. G. (2005). The reproducibility and sensitivity of the 6-min walk test in elderly patients with chronic heart failure. European Heart Journal, 26(17), 1742-1751. https://doi.org/10.1093/eurheartj/ehi259

Aims: The 6-min walk test (6-MWT) is used to estimate functional capacity. However, in elderly patients with chronic heart failure (CHF): (i) 1 year reproducibility of the 6-MWT; (ii) sensitivity of the 6-MWT to self-perceived changes in symptoms of... Read More about The reproducibility and sensitivity of the 6-min walk test in elderly patients with chronic heart failure.

Longitudinal myocardial dysfunction in healthy older subjects as a manifestation of cardiac ageing (2005)
Journal Article
Nikitin, N. P., Witte, K. K., Ingle, L., Clark, A. L., Farnsworth, T. A., & Cleland, J. G. (2005). Longitudinal myocardial dysfunction in healthy older subjects as a manifestation of cardiac ageing. Age and ageing, 34(4), 343-349. https://doi.org/10.1093/ageing/afi043

Background: Abnormalities of longitudinal left ventricular (LV) contraction and relaxation may be early markers of cardiac disease. This study was designed to assess the relationship between long-axis LV function and age in healthy subjects. Methods:... Read More about Longitudinal myocardial dysfunction in healthy older subjects as a manifestation of cardiac ageing.

Clinical trials update from the Heart Failure Society of America: EMOTE, HERB-CHF, BEST genetic sub-study and RHYTHM-ICD (2004)
Journal Article
Lalukota, K., Cleland, J. G., Ingle, L., Clark, A. L., & Coletta, A. P. (2004). Clinical trials update from the Heart Failure Society of America: EMOTE, HERB-CHF, BEST genetic sub-study and RHYTHM-ICD. European journal of heart failure, 6(7), 953-955. https://doi.org/10.1016/j.ejheart.2004.10.003

This article summarises key presentations relevant to the pathophysiology, prevention or treatment of heart failure, from the Heart Failure Society of America annual meeting held in Toronto, Canada. Data from the EnoxiMone in intravenous inOTropE-dep... Read More about Clinical trials update from the Heart Failure Society of America: EMOTE, HERB-CHF, BEST genetic sub-study and RHYTHM-ICD.

GP exercise referral schemes: improving the patient's experience (2004)
Journal Article
Wormald, H., & Ingle, L. (2004). GP exercise referral schemes: improving the patient's experience. The Health education journal, 63(4), 362-373. https://doi.org/10.1177/001789690406300407

Objective: The main objective of this study was to explore patients' perceptions of general practitioner (GP) exercise referral (ER) schemes with a view to providing a better service for future patients. Design: A qualitative focus group methodology.... Read More about GP exercise referral schemes: improving the patient's experience.

Influence of intervals of radiant heat on performance and pacing dynamics during rowing exercise
Book Chapter
Ingle, L., Butterly, R., & Lander, P. Influence of intervals of radiant heat on performance and pacing dynamics during rowing exercise.

Abstract: The purpose of this study was to investigate whether intervals of radiant heat during thermoneutral exercise altered either the performance outcome or the dynamics of pacing within the exercise bout. Eleven male participants ( ; 56 ± 12 ml∙... Read More about Influence of intervals of radiant heat on performance and pacing dynamics during rowing exercise.